FR2636330B1 - Procede de preparation de derives de morphinane - Google Patents
Procede de preparation de derives de morphinaneInfo
- Publication number
- FR2636330B1 FR2636330B1 FR8811930A FR8811930A FR2636330B1 FR 2636330 B1 FR2636330 B1 FR 2636330B1 FR 8811930 A FR8811930 A FR 8811930A FR 8811930 A FR8811930 A FR 8811930A FR 2636330 B1 FR2636330 B1 FR 2636330B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- morphinane derivatives
- morphinane
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8811930A FR2636330B1 (fr) | 1988-09-13 | 1988-09-13 | Procede de preparation de derives de morphinane |
EP89402472A EP0359647A1 (fr) | 1988-09-13 | 1989-09-11 | Procédé de préparation de dérivés de morphinane |
US07/406,248 US5071985A (en) | 1988-09-13 | 1989-09-12 | Process for the preparation of morphinane derivatives |
JP1236808A JPH02121993A (ja) | 1988-09-13 | 1989-09-12 | モルフィナン誘導体の製造方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8811930A FR2636330B1 (fr) | 1988-09-13 | 1988-09-13 | Procede de preparation de derives de morphinane |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2636330A1 FR2636330A1 (fr) | 1990-03-16 |
FR2636330B1 true FR2636330B1 (fr) | 1990-11-30 |
Family
ID=9369944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8811930A Expired - Fee Related FR2636330B1 (fr) | 1988-09-13 | 1988-09-13 | Procede de preparation de derives de morphinane |
Country Status (4)
Country | Link |
---|---|
US (1) | US5071985A (fr) |
EP (1) | EP0359647A1 (fr) |
JP (1) | JPH02121993A (fr) |
FR (1) | FR2636330B1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5668285A (en) * | 1986-10-31 | 1997-09-16 | The United States Of America As Represented By The Department Of Health And Human Services | Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates |
EP0846694A1 (fr) | 1992-01-23 | 1998-06-10 | Toray Industries, Inc. | Dérivés de morphinane et utilisation en médicine |
KR950000705A (ko) * | 1993-06-19 | 1995-01-03 | 권기범 | 14-치환 몰피난 유도체 및 이를 함유하는 의약 |
US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
CA2486157C (fr) | 2002-05-17 | 2013-04-16 | Jenken Biosciences, Inc. | Composes opioides et de type opioide et leurs utilisations |
AU2003263574A1 (en) | 2002-05-31 | 2003-12-19 | Patel, Hetalkumar, Virendrabhai | A process for the preparation of phenylcarbamates |
US8017622B2 (en) * | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US20080125592A1 (en) | 2006-10-17 | 2008-05-29 | Penick Corporation | Process for preparing oxymorphone, naltrexone, and buprenorphine |
AU2007313103C1 (en) | 2006-10-17 | 2014-01-30 | Penick Corporation | Process for preparing oxymorphone |
CA2674915C (fr) | 2006-10-17 | 2015-06-30 | Penick Corporation | Procede servant a preparer de l'oxymorphone |
GB0624880D0 (en) | 2006-12-14 | 2007-01-24 | Johnson Matthey Plc | Improved method for making analgesics |
US8217175B2 (en) * | 2007-03-23 | 2012-07-10 | Mallinckrodt Llc | Preparation of oxymorphone from oripavine |
US8309727B2 (en) * | 2007-04-16 | 2012-11-13 | Mallinckrodt Llc | Opiate reduction utilizing catalytic hydrogen transfer reaction |
CN102174049A (zh) * | 2011-03-11 | 2011-09-07 | 山东新华制药股份有限公司 | 一种盐酸纳洛酮成盐的制备工艺 |
CN103113378B (zh) * | 2013-02-20 | 2016-04-06 | 北京华素制药股份有限公司 | 一种盐酸羟吗啡酮的合成方法 |
AU2014298257B2 (en) | 2013-08-02 | 2016-11-10 | Macfarlan Smith Limited | Process for the preparation of oxymorphone |
GB201513203D0 (en) | 2015-07-27 | 2015-09-09 | Cambrex Charles City Inc | New process |
EP3252055B1 (fr) | 2016-05-31 | 2018-09-19 | Alcaliber Investigacion Desarrollo e Innovacion SLU | Procédé d'obtention de 3,14-diacetyloxymorphone à partir d'oripavine |
SK592017A3 (sk) | 2017-07-04 | 2019-01-08 | Saneca Pharmaceuticals A. S. | Spôsob prípravy morfínanových zlúčenín |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4265890A (en) * | 1978-07-07 | 1981-05-05 | Smithkline Corporation | 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines |
NO793297L (no) * | 1978-10-19 | 1980-04-22 | Mallinckrodt Inc | Fremgangsmaate til fremstilling av oksymorfon |
US4667037A (en) * | 1985-06-06 | 1987-05-19 | E. I. Du Pont De Nemours And Company | Dealkylation of opioid ethers |
US4707483A (en) * | 1985-12-20 | 1987-11-17 | Smithkline Beckman Corporation | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders |
-
1988
- 1988-09-13 FR FR8811930A patent/FR2636330B1/fr not_active Expired - Fee Related
-
1989
- 1989-09-11 EP EP89402472A patent/EP0359647A1/fr not_active Withdrawn
- 1989-09-12 US US07/406,248 patent/US5071985A/en not_active Expired - Fee Related
- 1989-09-12 JP JP1236808A patent/JPH02121993A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0359647A1 (fr) | 1990-03-21 |
FR2636330A1 (fr) | 1990-03-16 |
JPH02121993A (ja) | 1990-05-09 |
US5071985A (en) | 1991-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |