TW201238950A - NAMPT and rock inhibitors - Google Patents

NAMPT and rock inhibitors Download PDF

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Publication number
TW201238950A
TW201238950A TW100141323A TW100141323A TW201238950A TW 201238950 A TW201238950 A TW 201238950A TW 100141323 A TW100141323 A TW 100141323A TW 100141323 A TW100141323 A TW 100141323A TW 201238950 A TW201238950 A TW 201238950A
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TW
Taiwan
Prior art keywords
phenyl
dihydro
isoindole
carboxamide
amine
Prior art date
Application number
TW100141323A
Other languages
English (en)
Chinese (zh)
Inventor
Michael L Curtin
Bryan K Sorensen
Howard R Heyman
Richard F Clark
Kevin R Woller
Omar J Shah
Michael MICHAELIDES
Chris Tse
Anil Vasudevan
Helmut Mack
Todd M Hansen
Ramzi Sweis
Marina A Pliushchev
Original Assignee
Abbott Lab
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Application filed by Abbott Lab filed Critical Abbott Lab
Publication of TW201238950A publication Critical patent/TW201238950A/zh

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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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