TW201125581A - Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors - Google Patents

Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors Download PDF

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Publication number
TW201125581A
TW201125581A TW099134471A TW99134471A TW201125581A TW 201125581 A TW201125581 A TW 201125581A TW 099134471 A TW099134471 A TW 099134471A TW 99134471 A TW99134471 A TW 99134471A TW 201125581 A TW201125581 A TW 201125581A
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Taiwan
Prior art keywords
ngf
antibody
seq
ser
amino acid
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TW099134471A
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English (en)
Chinese (zh)
Inventor
Kenneth D Wild Jr
James J S Treanor
Haichun Huang
Heather Inoue
Tie J Zhang
Frank Martin
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Amgen Inc
Medarex Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43466840&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW201125581(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc, Medarex Inc filed Critical Amgen Inc
Publication of TW201125581A publication Critical patent/TW201125581A/zh

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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Virology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
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TW099134471A 2009-10-09 2010-10-08 Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors TW201125581A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/576,522 US9260514B2 (en) 2003-07-15 2009-10-09 Methods of treating conditions caused by increased expression of nerve growth factor (NGF) or increased sensitivity to NGF using anti-NGF neutralizing antibodies as selective NGF pathway inhibitors

Publications (1)

Publication Number Publication Date
TW201125581A true TW201125581A (en) 2011-08-01

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ID=43466840

Family Applications (1)

Application Number Title Priority Date Filing Date
TW099134471A TW201125581A (en) 2009-10-09 2010-10-08 Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors

Country Status (28)

Country Link
US (1) US9260514B2 (https=)
EP (2) EP3028717A1 (https=)
JP (3) JP2013507385A (https=)
KR (1) KR101528393B1 (https=)
CN (1) CN102762228A (https=)
AR (1) AR078569A1 (https=)
AU (2) AU2010308418A1 (https=)
BR (1) BR112012008282A2 (https=)
CA (1) CA2775924A1 (https=)
CL (1) CL2012000881A1 (https=)
CO (1) CO6541558A2 (https=)
CR (1) CR20120198A (https=)
EA (1) EA201290189A1 (https=)
IL (1) IL218885A0 (https=)
MA (1) MA33724B1 (https=)
ME (1) ME00226B (https=)
MT (1) MTP4289B (https=)
MX (1) MX343748B (https=)
MY (1) MY172283A (https=)
NZ (2) NZ625391A (https=)
PE (1) PE20121028A1 (https=)
PH (1) PH12012500668A1 (https=)
SG (1) SG10201603945RA (https=)
TN (1) TN2012000136A1 (https=)
TW (1) TW201125581A (https=)
UA (1) UA102775C2 (https=)
WO (1) WO2011049758A1 (https=)
ZA (1) ZA201203135B (https=)

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SG175436A1 (en) 2009-05-04 2011-12-29 Abbott Res Bv Antibodies against nerve growth factor (ngf) with enhanced in vivo stability
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
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