TR200103146T2 - 3-Deoksi-desmikozin türevleri ve bunları hazırlama işlemi - Google Patents

3-Deoksi-desmikozin türevleri ve bunları hazırlama işlemi

Info

Publication number
TR200103146T2
TR200103146T2 TR2001/03146T TR200103146T TR200103146T2 TR 200103146 T2 TR200103146 T2 TR 200103146T2 TR 2001/03146 T TR2001/03146 T TR 2001/03146T TR 200103146 T TR200103146 T TR 200103146T TR 200103146 T2 TR200103146 T2 TR 200103146T2
Authority
TR
Turkey
Prior art keywords
desmicosin
deoxy
derivatives
desmikozin
preparation process
Prior art date
Application number
TR2001/03146T
Other languages
English (en)
Inventor
Narandja Amalija
Lopotar Nevenka
Djerek Marko
Pavlovic Drazen
Original Assignee
Pliva Farmaceutska Industrija, Dionicko Dru�Tvo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Farmaceutska Industrija, Dionicko Dru�Tvo filed Critical Pliva Farmaceutska Industrija, Dionicko Dru�Tvo
Publication of TR200103146T2 publication Critical patent/TR200103146T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Mevcut bulus formül I' in 3-deoksi desmikozin türevleri ile ilgilidir, burada tripil korunmus olan desmikozinden baslayarak ilk asamada C-3' de bir oksidasyon gerçeklestirilmektedir ve daha sonra, istege bagli olarak, çift baglarin hidrojenlenmesini ve epoksidasyonunu, oksiran halkasinin bir indirgeyici açilisi izlemektedir. Mevcut bulus ayrica formül II' nin 3-deoksi-desmikozin türevleri ile de ilgilidir, burada ilk asamada triasetil desmikozin hidrojenlenmekte ve daha sonra, bir ara mezilat araciligiyla, bir 2,3-didehidro türrevine dönüstürülmekte; ya da 2,3-didehidro-desmikozin, oksiran halkasinin bir indirgeyici açilisi tarafindan takip edilen epoksidasyon reaksiyonlarina maruz birakilmaktadir.
TR2001/03146T 1999-05-03 2000-05-02 3-Deoksi-desmikozin türevleri ve bunları hazırlama işlemi TR200103146T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR990129A HRP990129B1 (en) 1999-05-03 1999-05-03 New compounds of 3-deoxy-desmycosin class and process for the preparation thereof

Publications (1)

Publication Number Publication Date
TR200103146T2 true TR200103146T2 (tr) 2002-05-21

Family

ID=10946915

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03146T TR200103146T2 (tr) 1999-05-03 2000-05-02 3-Deoksi-desmikozin türevleri ve bunları hazırlama işlemi

Country Status (31)

Country Link
US (1) US6504035B1 (tr)
EP (1) EP1175428B1 (tr)
JP (1) JP2002543212A (tr)
KR (1) KR100679903B1 (tr)
CN (1) CN1191263C (tr)
AT (1) ATE238332T1 (tr)
AU (1) AU767549B2 (tr)
BG (1) BG106172A (tr)
BR (1) BR0010250A (tr)
CA (1) CA2368249A1 (tr)
CZ (1) CZ296455B6 (tr)
DE (1) DE60002314T2 (tr)
DK (1) DK1175428T3 (tr)
EA (1) EA004059B1 (tr)
EE (1) EE04594B1 (tr)
ES (1) ES2198302T3 (tr)
GE (1) GEP20032927B (tr)
HK (1) HK1050010A1 (tr)
HR (1) HRP990129B1 (tr)
HU (1) HUP0201140A3 (tr)
IL (1) IL145989A0 (tr)
IS (1) IS6117A (tr)
MX (1) MXPA01011089A (tr)
NO (1) NO320141B1 (tr)
NZ (1) NZ515280A (tr)
PL (1) PL352027A1 (tr)
SK (1) SK283967B6 (tr)
TR (1) TR200103146T2 (tr)
UA (1) UA66927C2 (tr)
WO (1) WO2000066602A1 (tr)
ZA (1) ZA200108482B (tr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8405087D0 (en) * 1984-02-27 1984-04-04 Omura S Antibiotic
GB2171991B (en) * 1985-03-06 1988-08-17 Satoshi Omura Novel macrolide derivatives, process for preparing same, and antibacterial compositions thereof
JPS62221695A (ja) * 1986-03-24 1987-09-29 Microbial Chem Res Found タイロシンオキシム誘導体およびその製造法
YU45033B (en) * 1987-04-14 1991-06-30 Pliva Zagreb Process for preparing 10,11,12,13-tetrahydro derivative
JPH05230094A (ja) * 1992-02-26 1993-09-07 Asahi Chem Ind Co Ltd マイシナマイシン誘導体

Also Published As

Publication number Publication date
HUP0201140A2 (en) 2002-08-28
HRP990129A2 (en) 2001-12-31
SK15682001A3 (sk) 2002-06-04
EE200100571A (et) 2003-02-17
ES2198302T3 (es) 2004-02-01
US6504035B1 (en) 2003-01-07
ZA200108482B (en) 2002-12-24
CN1191263C (zh) 2005-03-02
UA66927C2 (uk) 2004-06-15
JP2002543212A (ja) 2002-12-17
EP1175428B1 (en) 2003-04-23
EP1175428A1 (en) 2002-01-30
CA2368249A1 (en) 2000-11-09
PL352027A1 (en) 2003-07-28
NZ515280A (en) 2002-12-20
GEP20032927B (en) 2003-03-25
NO20015347D0 (no) 2001-11-01
CZ296455B6 (cs) 2006-03-15
IL145989A0 (en) 2002-07-25
KR100679903B1 (ko) 2007-02-28
DE60002314D1 (de) 2003-05-28
DE60002314T2 (de) 2004-03-04
MXPA01011089A (es) 2002-07-22
NO320141B1 (no) 2005-10-31
WO2000066602A9 (en) 2001-12-20
NO20015347L (no) 2001-11-01
DK1175428T3 (da) 2003-08-11
HUP0201140A3 (en) 2003-03-28
KR20020007396A (ko) 2002-01-26
CN1362963A (zh) 2002-08-07
BG106172A (bg) 2002-07-31
EA200101169A1 (ru) 2002-04-25
HK1050010A1 (zh) 2003-06-06
CZ20013821A3 (cs) 2002-03-13
WO2000066602A1 (en) 2000-11-09
AU4134900A (en) 2000-11-17
EA004059B1 (ru) 2003-12-25
ATE238332T1 (de) 2003-05-15
IS6117A (is) 2001-10-19
SK283967B6 (sk) 2004-06-08
BR0010250A (pt) 2002-02-19
AU767549B2 (en) 2003-11-13
EE04594B1 (et) 2006-02-15
HRP990129B1 (en) 2003-10-31

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