TR200001056T2 - Hızlı çözülen farmasötik terkipler. - Google Patents
Hızlı çözülen farmasötik terkipler.Info
- Publication number
- TR200001056T2 TR200001056T2 TR2000/01056T TR200001056T TR200001056T2 TR 200001056 T2 TR200001056 T2 TR 200001056T2 TR 2000/01056 T TR2000/01056 T TR 2000/01056T TR 200001056 T TR200001056 T TR 200001056T TR 200001056 T2 TR200001056 T2 TR 200001056T2
- Authority
- TR
- Turkey
- Prior art keywords
- rapidly dissolving
- pharmaceutical compositions
- dissolving pharmaceutical
- pharmaceutical composition
- tetrahydropyrolo
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- -1 4-bromo-2-fluoro-benzyl Chemical group 0.000 abstract 1
- 102000016912 Aldehyde Reductase Human genes 0.000 abstract 1
- 108010053754 Aldehyde reductase Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/499—Spiro-condensed pyrazines or piperazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Bu bulus, kuvvetli bir aldoz redüktaz inhibitör etkisi olan (R)-2-(4-bromo-2-floro-benzil) -1,2,3,4-tetrahidropirrolo [1,2-a]pirazin-4-spiro-3'-pirrolidin-1, 2',3,5'-tetron' un (bundan sonra "AS-3201" olarak geçecektir) hizli çözülen bir farmasötik terkip ile ilgilidir. Bu farmasötik terkip hem gelismis erime özelliklerine sahip olup hem de biyolojik bakimdan kolay elde edilebilmektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP30663597 | 1997-10-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200001056T2 true TR200001056T2 (tr) | 2000-09-21 |
Family
ID=17959478
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/01056T TR200001056T2 (tr) | 1997-10-20 | 1998-10-15 | Hızlı çözülen farmasötik terkipler. |
Country Status (22)
Country | Link |
---|---|
US (2) | US7141249B2 (tr) |
EP (1) | EP1033132B1 (tr) |
KR (1) | KR100571614B1 (tr) |
CN (1) | CN1156277C (tr) |
AT (1) | ATE296101T1 (tr) |
AU (1) | AU740299B2 (tr) |
BR (1) | BR9814090A (tr) |
CA (1) | CA2306883C (tr) |
CZ (1) | CZ299018B6 (tr) |
DE (1) | DE69830333T2 (tr) |
ES (1) | ES2242298T3 (tr) |
HK (1) | HK1030359A1 (tr) |
HU (1) | HUP0004132A3 (tr) |
ID (1) | ID23915A (tr) |
NO (1) | NO319049B1 (tr) |
NZ (1) | NZ503796A (tr) |
PL (1) | PL191533B1 (tr) |
PT (1) | PT1033132E (tr) |
RU (1) | RU2203665C2 (tr) |
TR (1) | TR200001056T2 (tr) |
TW (1) | TW592728B (tr) |
WO (1) | WO1999020277A1 (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9814090A (pt) * | 1997-10-20 | 2000-10-03 | Dainippon Pharmaceutical Co | Composição de drogas rapidamente solúvel |
BRPI0611409B8 (pt) | 2005-05-26 | 2021-05-25 | Dainippon Sumitomo Pharma Co | preparação oral compreendendo lurasidona |
KR20110044780A (ko) | 2008-08-14 | 2011-04-29 | 교린 세이야꾸 가부시키 가이샤 | 안정화된 의약 조성물 |
CN105769809A (zh) * | 2014-12-23 | 2016-07-20 | 上海星泰医药科技有限公司 | 提高生物利用度的雷尼司他及其制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK607188A (da) * | 1987-11-02 | 1989-06-22 | Merck & Co Inc | Tablet indeholdende en phthalazineddikesyreforbindelse |
TW202450B (tr) | 1991-06-26 | 1993-03-21 | Dainippon Pharmaceutical Co | |
JPH0518672A (ja) * | 1991-07-09 | 1993-01-26 | Daido Steel Co Ltd | 熱処理炉の冷却域における炉体構造 |
DE4141351A1 (de) * | 1991-12-14 | 1993-06-17 | Basf Ag | Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung |
DE4400464A1 (de) * | 1994-01-11 | 1995-07-13 | Bayer Ag | Endoparasitizide Mittel |
DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
TWI238064B (en) * | 1995-06-20 | 2005-08-21 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
US6458811B1 (en) * | 1996-03-26 | 2002-10-01 | Eli Lilly And Company | Benzothiophenes formulations containing same and methods |
DK1038525T3 (da) * | 1997-10-20 | 2004-08-02 | Dainippon Pharmaceutical Co | Stabiliseret farmaceutisk præparat af tetrahydropyrrolo[1,2-a]pyrazin-4-spiro-3'-pyrrolidin |
BR9814090A (pt) * | 1997-10-20 | 2000-10-03 | Dainippon Pharmaceutical Co | Composição de drogas rapidamente solúvel |
-
1998
- 1998-10-15 BR BR9814090-6A patent/BR9814090A/pt not_active Application Discontinuation
- 1998-10-15 PL PL340045A patent/PL191533B1/pl not_active IP Right Cessation
- 1998-10-15 US US09/529,715 patent/US7141249B2/en not_active Expired - Fee Related
- 1998-10-15 AT AT98947883T patent/ATE296101T1/de active
- 1998-10-15 TR TR2000/01056T patent/TR200001056T2/tr unknown
- 1998-10-15 PT PT98947883T patent/PT1033132E/pt unknown
- 1998-10-15 RU RU2000112538/14A patent/RU2203665C2/ru not_active IP Right Cessation
- 1998-10-15 ES ES98947883T patent/ES2242298T3/es not_active Expired - Lifetime
- 1998-10-15 CZ CZ20001418A patent/CZ299018B6/cs not_active IP Right Cessation
- 1998-10-15 CA CA002306883A patent/CA2306883C/en not_active Expired - Fee Related
- 1998-10-15 CN CNB98812372XA patent/CN1156277C/zh not_active Expired - Fee Related
- 1998-10-15 ID IDW20000676A patent/ID23915A/id unknown
- 1998-10-15 EP EP98947883A patent/EP1033132B1/en not_active Expired - Lifetime
- 1998-10-15 NZ NZ503796A patent/NZ503796A/en not_active IP Right Cessation
- 1998-10-15 DE DE69830333T patent/DE69830333T2/de not_active Expired - Lifetime
- 1998-10-15 HU HU0004132A patent/HUP0004132A3/hu unknown
- 1998-10-15 AU AU94619/98A patent/AU740299B2/en not_active Ceased
- 1998-10-15 KR KR1020007004191A patent/KR100571614B1/ko not_active IP Right Cessation
- 1998-10-15 WO PCT/JP1998/004658 patent/WO1999020277A1/ja active IP Right Grant
- 1998-10-19 TW TW087117258A patent/TW592728B/zh not_active IP Right Cessation
-
2000
- 2000-04-18 NO NO20002049A patent/NO319049B1/no not_active IP Right Cessation
-
2001
- 2001-01-29 HK HK01100617A patent/HK1030359A1/xx not_active IP Right Cessation
-
2006
- 2006-08-03 US US11/498,147 patent/US20060269599A1/en not_active Abandoned
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