TR199701254T1 - 5-HT alis inhibitörünün selektif 5-HT1A antagonistiyle kombinasyonu. - Google Patents
5-HT alis inhibitörünün selektif 5-HT1A antagonistiyle kombinasyonu.Info
- Publication number
- TR199701254T1 TR199701254T1 TR97/01254T TR9701254T TR199701254T1 TR 199701254 T1 TR199701254 T1 TR 199701254T1 TR 97/01254 T TR97/01254 T TR 97/01254T TR 9701254 T TR9701254 T TR 9701254T TR 199701254 T1 TR199701254 T1 TR 199701254T1
- Authority
- TR
- Turkey
- Prior art keywords
- combination
- selective
- combinations
- inhibitor
- ht1a antagonist
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Mevcut bulus bir 5-HT yeniden alis inhibitörü olan bir birinci komponent (a) ile formül I'e göre olan selektif 5-HT1A antagonisti olan bir ikinci konponent'ten (b) olusan bir kombinasyon, ki burada R1 n-propil ya da siklobutil'i ifade etmekte; R2 izopropil, tertier butil, siklobutil, siklopentil ya da sikloheksil'i; R3 hidrojen'i; R4 hidrojen ya da metil'i ifade etmektedir; (R) -enantiyomerin serbest baz ya da bunun ispençiyari kabul edilebilir tuzlari olarak söz konusu kombinasyonu, bunlarin hazirlanmasi, söz konusu kombinasyonlari ihtiva eden ispençiyari formülasyonlari, söz konusu kombinasyonlarin depresyon, endise ve OCD gibi rahatsizliklarin etkili tedavi edilmesi için kullanimi ve buna yönelik usul ve ayrica söz konusu bu kombinasyonlari ihtiva eden bir cihaz ile ilgilidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9501567A SE9501567D0 (sv) | 1995-04-27 | 1995-04-27 | A new combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199701254T1 true TR199701254T1 (tr) | 1998-02-21 |
Family
ID=20398119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR97/01254T TR199701254T1 (tr) | 1995-04-27 | 1996-04-23 | 5-HT alis inhibitörünün selektif 5-HT1A antagonistiyle kombinasyonu. |
Country Status (30)
| Country | Link |
|---|---|
| US (5) | US5962514A (tr) |
| EP (1) | EP0822813B1 (tr) |
| JP (1) | JPH11504037A (tr) |
| KR (1) | KR100419810B1 (tr) |
| CN (1) | CN1102386C (tr) |
| AR (1) | AR002990A1 (tr) |
| AT (1) | ATE216579T1 (tr) |
| BR (1) | BR9608252A (tr) |
| CA (1) | CA2218181A1 (tr) |
| CZ (1) | CZ335697A3 (tr) |
| DE (1) | DE69620878T2 (tr) |
| DK (1) | DK0822813T3 (tr) |
| EE (1) | EE03553B1 (tr) |
| ES (1) | ES2175089T3 (tr) |
| HK (1) | HK1002853A1 (tr) |
| HU (1) | HUP9801946A3 (tr) |
| IL (1) | IL117988A0 (tr) |
| IS (1) | IS1821B (tr) |
| NO (1) | NO317057B1 (tr) |
| NZ (1) | NZ306602A (tr) |
| PL (1) | PL183997B1 (tr) |
| PT (1) | PT822813E (tr) |
| RU (1) | RU2183955C2 (tr) |
| SE (1) | SE9501567D0 (tr) |
| SK (1) | SK282060B6 (tr) |
| TR (1) | TR199701254T1 (tr) |
| TW (1) | TW458777B (tr) |
| WO (1) | WO1996033710A1 (tr) |
| YU (1) | YU25696A (tr) |
| ZA (1) | ZA962982B (tr) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9501567D0 (sv) * | 1995-04-27 | 1995-04-27 | Astra Ab | A new combination |
| SE9703374D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | A new combination |
| AU4100699A (en) * | 1998-05-28 | 1999-12-13 | Sepracor, Inc. | Compositions and methods employing r(-) fluoxetine and other active ingredients |
| SE9803157D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| SE9803155D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| SE9803158D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| SE9803156D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| AR021155A1 (es) * | 1999-07-08 | 2002-06-12 | Lundbeck & Co As H | Tratamiento de desordenes neuroticos |
| UA77650C2 (en) * | 1999-12-06 | 2007-01-15 | Lundbeck & Co As H | Use of serotonin reuptake inhibitor in combination with deramcyclane |
| US6331233B1 (en) | 2000-02-02 | 2001-12-18 | Honeywell International Inc. | Tantalum sputtering target with fine grains and uniform texture and method of manufacture |
| ES2269467T3 (es) | 2000-10-13 | 2007-04-01 | Neurosearch A/S | Tratamiento de transtornos afectivos por la accion combinada de un agonista del receptor nicotinico y una sustancia monoaminergenica. |
| US20030166554A1 (en) * | 2001-01-16 | 2003-09-04 | Genset, S.A. | Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists |
| US20030185754A1 (en) * | 2001-01-16 | 2003-10-02 | Genset, S.A. | Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists |
| CA2445843A1 (en) * | 2001-05-01 | 2002-11-07 | H. Lundbeck A/S | The use of enantiomeric pure escitalopram |
| US7034059B2 (en) | 2001-07-02 | 2006-04-25 | Sepracor Inc. | Methods of using norfluoxetine |
| US6855735B2 (en) | 2002-03-20 | 2005-02-15 | Temple University Of The Commonwealth System Of Higher Education | Ketamine treatment of restless legs syndrome |
| KR20050040921A (ko) * | 2002-08-15 | 2005-05-03 | 와이어쓰 | 체온조절 기능장애 치료를 위한 5ＨＴ2ａ 수용체의 항진제 |
| US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
| US7695601B2 (en) * | 2006-05-09 | 2010-04-13 | The United States Of America As Represented By The Secretary Of The Army | Electrochemical test apparatus and method for its use |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| WO2015006643A2 (en) * | 2013-07-12 | 2015-01-15 | Immuneering Corporation | Systems, methods, and environment for automated review of genomic data to identify downregulated and/or upregulated gene expression indicative of a disease or condition |
| CA3049464A1 (en) | 2017-02-14 | 2018-08-23 | Research Triangle Institute | Proline-based neuropeptide ff receptor modulators |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4698342A (en) * | 1985-07-16 | 1987-10-06 | Serotonin Industries Of Charleston | Method and compositions for controlling pain, depression and sedation |
| US5616610A (en) * | 1989-12-22 | 1997-04-01 | Astra Aktiebolag | (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans |
| US5420151A (en) * | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
| SE9501567D0 (sv) * | 1995-04-27 | 1995-04-27 | Astra Ab | A new combination |
-
1995
- 1995-04-27 SE SE9501567A patent/SE9501567D0/xx unknown
-
1996
- 1996-04-15 ZA ZA962982A patent/ZA962982B/xx unknown
- 1996-04-15 TW TW085104481A patent/TW458777B/zh not_active IP Right Cessation
- 1996-04-21 IL IL11798896A patent/IL117988A0/xx not_active IP Right Cessation
- 1996-04-23 PT PT96912370T patent/PT822813E/pt unknown
- 1996-04-23 HU HU9801946A patent/HUP9801946A3/hu unknown
- 1996-04-23 ES ES96912370T patent/ES2175089T3/es not_active Expired - Lifetime
- 1996-04-23 WO PCT/SE1996/000526 patent/WO1996033710A1/en active IP Right Grant
- 1996-04-23 DE DE69620878T patent/DE69620878T2/de not_active Expired - Fee Related
- 1996-04-23 CZ CZ973356A patent/CZ335697A3/cs unknown
- 1996-04-23 US US08/640,896 patent/US5962514A/en not_active Expired - Fee Related
- 1996-04-23 TR TR97/01254T patent/TR199701254T1/tr unknown
- 1996-04-23 DK DK96912370T patent/DK0822813T3/da active
- 1996-04-23 KR KR1019970707592A patent/KR100419810B1/ko not_active IP Right Cessation
- 1996-04-23 JP JP8532425A patent/JPH11504037A/ja not_active Ceased
- 1996-04-23 EE EE9700245A patent/EE03553B1/xx not_active IP Right Cessation
- 1996-04-23 NZ NZ306602A patent/NZ306602A/en unknown
- 1996-04-23 RU RU97119427/14A patent/RU2183955C2/ru active
- 1996-04-23 AT AT96912370T patent/ATE216579T1/de not_active IP Right Cessation
- 1996-04-23 CA CA002218181A patent/CA2218181A1/en not_active Abandoned
- 1996-04-23 SK SK1429-97A patent/SK282060B6/sk unknown
- 1996-04-23 BR BR9608252A patent/BR9608252A/pt not_active Application Discontinuation
- 1996-04-23 PL PL96323083A patent/PL183997B1/pl unknown
- 1996-04-23 EP EP96912370A patent/EP0822813B1/en not_active Expired - Lifetime
- 1996-04-23 CN CN96194810A patent/CN1102386C/zh not_active Expired - Fee Related
- 1996-04-25 AR ARP960102323A patent/AR002990A1/es not_active Application Discontinuation
- 1996-04-26 YU YU25696A patent/YU25696A/sh unknown
-
1997
- 1997-10-09 IS IS4585A patent/IS1821B/is unknown
- 1997-10-24 NO NO19974921A patent/NO317057B1/no unknown
-
1998
- 1998-03-10 HK HK98101990A patent/HK1002853A1/xx not_active IP Right Cessation
-
1999
- 1999-07-09 US US09/351,069 patent/US6169098B1/en not_active Expired - Fee Related
- 1999-07-09 US US09/351,070 patent/US6172105B1/en not_active Expired - Fee Related
- 1999-07-09 US US09/351,071 patent/US6184219B1/en not_active Expired - Fee Related
- 1999-07-09 US US09/349,590 patent/US6184218B1/en not_active Expired - Fee Related
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