SE9703374D0 - A new combination - Google Patents

A new combination

Info

Publication number
SE9703374D0
SE9703374D0 SE9703374A SE9703374A SE9703374D0 SE 9703374 D0 SE9703374 D0 SE 9703374D0 SE 9703374 A SE9703374 A SE 9703374A SE 9703374 A SE9703374 A SE 9703374A SE 9703374 D0 SE9703374 D0 SE 9703374D0
Authority
SE
Sweden
Prior art keywords
combination
pct
enantiomer
cyclobutyl
sec
Prior art date
Application number
SE9703374A
Other languages
English (en)
Inventor
Stefan Berg
Svante Ross
Seth-Olov Thorberg
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9703374A priority Critical patent/SE9703374D0/sv
Publication of SE9703374D0 publication Critical patent/SE9703374D0/sv
Priority to ZA987810A priority patent/ZA987810B/xx
Priority to TW087114345A priority patent/TW568786B/zh
Priority to ES98944374T priority patent/ES2216307T3/es
Priority to NZ503174A priority patent/NZ503174A/en
Priority to DK98944374T priority patent/DK1021183T3/da
Priority to SK284-2000A priority patent/SK2842000A3/sk
Priority to PL98339370A priority patent/PL339370A1/xx
Priority to RU2000109558/14A priority patent/RU2215528C2/ru
Priority to PCT/SE1998/001600 priority patent/WO1999013876A1/en
Priority to EP98944374A priority patent/EP1021183B1/en
Priority to US09/171,581 priority patent/US6159972A/en
Priority to BR9812234-7A priority patent/BR9812234A/pt
Priority to TR2000/00734T priority patent/TR200000734T2/xx
Priority to KR1020007002821A priority patent/KR20010024075A/ko
Priority to DE69822490T priority patent/DE69822490T2/de
Priority to AU91929/98A priority patent/AU752718B2/en
Priority to PT98944374T priority patent/PT1021183E/pt
Priority to CNB988112493A priority patent/CN1182847C/zh
Priority to IL13477498A priority patent/IL134774A0/xx
Priority to EEP200000143A priority patent/EE04142B1/xx
Priority to JP2000511498A priority patent/JP2001516717A/ja
Priority to SI9830629T priority patent/SI1021183T1/xx
Priority to CA002302383A priority patent/CA2302383A1/en
Priority to HU0100401A priority patent/HUP0100401A3/hu
Priority to AT98944374T priority patent/ATE261728T1/de
Priority to MYPI98004226A priority patent/MY116281A/en
Priority to ARP980104633A priority patent/AR015447A1/es
Priority to IS5408A priority patent/IS5408A/is
Priority to NO20001398A priority patent/NO20001398L/no
Priority to HK00107467A priority patent/HK1032740A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
SE9703374A 1997-09-18 1997-09-18 A new combination SE9703374D0 (sv)

Priority Applications (31)

Application Number Priority Date Filing Date Title
SE9703374A SE9703374D0 (sv) 1997-09-18 1997-09-18 A new combination
ZA987810A ZA987810B (en) 1997-09-18 1998-08-27 A combination of a selective 5HT1A antagonist and a selective h5-HT1B antagonist or partial agonist
TW087114345A TW568786B (en) 1997-09-18 1998-08-29 A combination, pharmaceutical formulation, and kit for use in the treatment of affective disorders
AT98944374T ATE261728T1 (de) 1997-09-18 1998-09-09 Kombination eines selektiven 5-ht1a antagonisten und eines selektiven h5-ht1b antagonisten oder partiellen agonisten
KR1020007002821A KR20010024075A (ko) 1997-09-18 1998-09-09 선택적 5-ＨＴ1Ａ 길항제 및 선택적 ｈ5-ＨＴ1Ｂ 길항제또는 부분 작용제의 배합물
AU91929/98A AU752718B2 (en) 1997-09-18 1998-09-09 A combination of a selective 5-HT1A antagonist and a selective h5-HT1B antagonist or partial agonist
DK98944374T DK1021183T3 (da) 1997-09-18 1998-09-09 En kombination af en selektiv 5-HT 1A-antagonist og en selektiv h5-HT 1B-antagonist eller partiel antagonist
SK284-2000A SK2842000A3 (en) 1997-09-18 1998-09-09 A COMBINATION OF A SELECTIVE 5-HT1A ANTAGONIST AND A SELECTIVEì (54) H5-HT1B ANTAGONIST OR PARTIAL AGONIST
PL98339370A PL339370A1 (en) 1997-09-18 1998-09-09 Composition containing selective antagonist of 5-ht 1a and selective antagonist or partial agonist of h5-ht 1b
RU2000109558/14A RU2215528C2 (ru) 1997-09-18 1998-09-09 Комбинация селективного антагониста 5-нт1a и селективного антагониста или частичного агониста н5-нт1b
PCT/SE1998/001600 WO1999013876A1 (en) 1997-09-18 1998-09-09 A COMBINATION OF A SELECTIVE 5-HT1A ANTAGONIST AND A SELECTIVE h5-HT1B ANTAGONIST OR PARTIAL AGONIST
EP98944374A EP1021183B1 (en) 1997-09-18 1998-09-09 A COMBINATION OF A SELECTIVE 5-HT1A ANTAGONIST AND A SELECTIVE h5-HT1B ANTAGONIST OR PARTIAL AGONIST
US09/171,581 US6159972A (en) 1997-09-18 1998-09-09 Combination of a selective 5-HT1A antagonist and a selective ub. h5-HT.s1B antagonist or partial agonist
BR9812234-7A BR9812234A (pt) 1997-09-18 1998-09-09 Combinação de componentes, uso desta, processos para a preparação da mesma, para o tratamento de distúrbios afetivos, para o tratamento de depressão, e para melhorar o inìcio de ação terapêutica, formulação farmacêutica, e, kit
TR2000/00734T TR200000734T2 (tr) 1997-09-18 1998-09-09 Seçici bir 5-HT1A/5-HT1B antagonistinin veya kısmi antagonistinin bir bileşimi.
ES98944374T ES2216307T3 (es) 1997-09-18 1998-09-09 Una combinacion de un antagonista de 5-ht1a selectivo y un antagonista o agonista parcial de h5-ht1b selectivo.
DE69822490T DE69822490T2 (de) 1997-09-18 1998-09-09 KOMBINATION EINES SELEKTIVEN 5-HT1A ANTAGONISTEN UND EINES SELEKTIVEN h5-HT1B ANTAGONISTEN ODER PARTIELLEN AGONISTEN
NZ503174A NZ503174A (en) 1997-09-18 1998-09-09 A synergistic combination of a benzopyran selective 5-HT 1A antagonist and a selective h5-HT 1B antagonist or partial agonist
PT98944374T PT1021183E (pt) 1997-09-18 1998-09-09 Combinacao de um antagonista selectivo para 5-htla e de um antagonista selectivo para hs-ht1b ou agonista parcial
CNB988112493A CN1182847C (zh) 1997-09-18 1998-09-09 选择性5－HT1A拮抗剂和选择性h5－HT1B拮抗剂或部分激动剂的联用产品
IL13477498A IL134774A0 (en) 1997-09-18 1998-09-09 A COMBINATION OF A SELECTIVE 5-HT1A ANTAGONIST AND A SELECTIVE h5-HT1B ANTAGONIST OR PARTIAL AGONIST
EEP200000143A EE04142B1 (et) 1997-09-18 1998-09-09 Selektiivse 5-HT 1A antagonisti kombinatsioon selektiivse h5-HT 1B antagonisti või osalise agonistiga
JP2000511498A JP2001516717A (ja) 1997-09-18 1998-09-09 選択的５−ＨＴ１Ａアンタゴニストおよび選択的ｈ５−ＨＴ１Ｂアンタゴニストまたは部分的アゴニストの組み合わせ
SI9830629T SI1021183T1 (en) 1997-09-18 1998-09-09 A COMBINATION OF A SELECTIVE 5-HT1A ANTAGONIST AND A SELECTIVE h5-HT1B ANTAGONIST OR PARTIAL AGONIST
CA002302383A CA2302383A1 (en) 1997-09-18 1998-09-09 A combination of a selective 5-ht1a antagonist and a selective h5-ht1b antagonist or partial agonist
HU0100401A HUP0100401A3 (en) 1997-09-18 1998-09-09 Medicaments containing a combination of a selective 5-ht1a antagonist and a selective h5-ht1b antagonist or partial agonist, and method for producing
MYPI98004226A MY116281A (en) 1997-09-18 1998-09-16 A combination of a selective 5-ht 1a antagonist and a selective h5-ht 1b antagonist or partial agonist.
ARP980104633A AR015447A1 (es) 1997-09-18 1998-09-17 COMBINACIoN DE UN ANTAGONISTA DE 5HT1A SELECTIVO Y UN ANTAGONISTA O AGONISTA PARCIAL DE H5-HT1B SELECTIVO, PROCESO PARA SU PREPARACIoN, FORMULACIONES FARMACÉUTICAS QUE LO CONTIENEN, SU USO PARA LA MANUFACTURA DE UN MEDICAMENTO PARA EL TRATAMIENTO DE TRASTORNOS AFECTIVOS Y KIT QUE CONTIENE DICHA COMB
IS5408A IS5408A (is) 1997-09-18 2000-03-15 Samsetning valvísra 5-HT1A mótlyfja og valvíss h5-HT1B mótlyfs eða gerandefnis með hlutaverkun
NO20001398A NO20001398L (no) 1997-09-18 2000-03-17 Kombinasjon av en 5-HT1A antagonist og en selektiv h5-HT1B antagonist eller partial antagonist
HK00107467A HK1032740A1 (en) 1997-09-18 2000-11-22 A combination of a selective 5-ht1a antagonist and a selective h5-ht1b antagonist or partial agonist

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9703374A SE9703374D0 (sv) 1997-09-18 1997-09-18 A new combination

Publications (1)

Publication Number Publication Date
SE9703374D0 true SE9703374D0 (sv) 1997-09-18

Family

ID=20408294

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9703374A SE9703374D0 (sv) 1997-09-18 1997-09-18 A new combination

Country Status (30)

Country Link
US (1) US6159972A (sv)
EP (1) EP1021183B1 (sv)
JP (1) JP2001516717A (sv)
KR (1) KR20010024075A (sv)
CN (1) CN1182847C (sv)
AR (1) AR015447A1 (sv)
AT (1) ATE261728T1 (sv)
AU (1) AU752718B2 (sv)
BR (1) BR9812234A (sv)
CA (1) CA2302383A1 (sv)
DE (1) DE69822490T2 (sv)
DK (1) DK1021183T3 (sv)
EE (1) EE04142B1 (sv)
ES (1) ES2216307T3 (sv)
HK (1) HK1032740A1 (sv)
HU (1) HUP0100401A3 (sv)
IL (1) IL134774A0 (sv)
IS (1) IS5408A (sv)
MY (1) MY116281A (sv)
NO (1) NO20001398L (sv)
NZ (1) NZ503174A (sv)
PL (1) PL339370A1 (sv)
PT (1) PT1021183E (sv)
RU (1) RU2215528C2 (sv)
SE (1) SE9703374D0 (sv)
SK (1) SK2842000A3 (sv)
TR (1) TR200000734T2 (sv)
TW (1) TW568786B (sv)
WO (1) WO1999013876A1 (sv)
ZA (1) ZA987810B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9601110D0 (sv) 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives
WO2002066454A1 (en) * 2001-02-21 2002-08-29 Sankyo Company, Limited Chromene derivatives
JP5080716B2 (ja) * 2001-07-20 2012-11-21 サイコジェニックス・インコーポレーテッド 注意欠陥・多動性障害の治療
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
USD969016S1 (en) 2021-06-28 2022-11-08 Koninklijke Asscher Diamant Maatschappij B.V. Rose oval diamond article

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9410512D0 (en) * 1994-05-25 1994-07-13 Smithkline Beecham Plc Novel treatment
SE9501567D0 (sv) * 1995-04-27 1995-04-27 Astra Ab A new combination
FI961247A0 (fi) * 1996-03-18 1996-03-18 Finnish Peroxides Ab Oy Foerfarande foer loesning av uppsvaellningsproblem i en avfalls vattenreningsanordning foer kontroll av traodartiga bakterier
SE9601110D0 (sv) * 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Also Published As

Publication number Publication date
KR20010024075A (ko) 2001-03-26
EP1021183B1 (en) 2004-03-17
US6159972A (en) 2000-12-12
MY116281A (en) 2003-12-31
EP1021183A1 (en) 2000-07-26
ATE261728T1 (de) 2004-04-15
IL134774A0 (en) 2001-04-30
DE69822490D1 (de) 2004-04-22
IS5408A (is) 2000-03-15
AR015447A1 (es) 2001-05-02
AU752718B2 (en) 2002-09-26
HK1032740A1 (en) 2001-08-03
PL339370A1 (en) 2000-12-18
WO1999013876A1 (en) 1999-03-25
RU2215528C2 (ru) 2003-11-10
AU9192998A (en) 1999-04-05
CA2302383A1 (en) 1999-03-25
SK2842000A3 (en) 2000-09-12
NO20001398D0 (no) 2000-03-17
HUP0100401A2 (hu) 2002-01-28
TW568786B (en) 2004-01-01
NO20001398L (no) 2000-04-04
JP2001516717A (ja) 2001-10-02
EE200000143A (et) 2001-02-15
PT1021183E (pt) 2004-07-30
EE04142B1 (et) 2003-10-15
CN1182847C (zh) 2005-01-05
NZ503174A (en) 2002-03-01
BR9812234A (pt) 2000-07-18
DK1021183T3 (da) 2004-07-05
TR200000734T2 (tr) 2000-11-21
CN1279609A (zh) 2001-01-10
ZA987810B (en) 1999-02-18
HUP0100401A3 (en) 2003-01-28
DE69822490T2 (de) 2005-03-03
ES2216307T3 (es) 2004-10-16

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