FI945581A0 - Substituerade (arylalkoxibensyl) aminopropanamidderivat, deras framställning och användning som antiepileptiska, neuroprotektiva och antidepressiva medel - Google Patents

Substituerade (arylalkoxibensyl) aminopropanamidderivat, deras framställning och användning som antiepileptiska, neuroprotektiva och antidepressiva medel

Info

Publication number
FI945581A0
FI945581A0 FI945581A FI945581A FI945581A0 FI 945581 A0 FI945581 A0 FI 945581A0 FI 945581 A FI945581 A FI 945581A FI 945581 A FI945581 A FI 945581A FI 945581 A0 FI945581 A0 FI 945581A0
Authority
FI
Finland
Prior art keywords
neuroprotective
hydrogen
arylalkoxybenzyl
antiepileptic
substituted
Prior art date
Application number
FI945581A
Other languages
English (en)
Finnish (fi)
Other versions
FI945581A (sv
Inventor
Mario Varasi
Philippe Dostert
Paolo Pevarello
Alberto Bonsignori
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI945581A0 publication Critical patent/FI945581A0/sv
Publication of FI945581A publication Critical patent/FI945581A/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI945581A 1993-04-01 1994-11-28 Substituerade (arylalkoxibensyl) aminopropanamidderivat, deras framställning och användning som antiepileptiska, neuroprotektiva och antidepressiva medel FI945581A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939306886A GB9306886D0 (en) 1993-04-01 1993-04-01 Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
PCT/EP1994/000802 WO1994022808A1 (en) 1993-04-01 1994-03-15 Substituted (arylalkoxybenzyl)aminopropanamide derivatives, their preparation and use as anti-epileptic, neuroprotective and antidepressant agents

Publications (2)

Publication Number Publication Date
FI945581A0 true FI945581A0 (sv) 1994-11-28
FI945581A FI945581A (sv) 1994-11-28

Family

ID=10733215

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945581A FI945581A (sv) 1993-04-01 1994-11-28 Substituerade (arylalkoxibensyl) aminopropanamidderivat, deras framställning och användning som antiepileptiska, neuroprotektiva och antidepressiva medel

Country Status (19)

Country Link
US (1) US5446066A (sv)
EP (1) EP0643688B1 (sv)
JP (1) JP3542599B2 (sv)
KR (1) KR950701904A (sv)
CN (1) CN1035938C (sv)
AT (1) ATE168991T1 (sv)
AU (1) AU667164B2 (sv)
CA (1) CA2135783C (sv)
DE (1) DE69412016T2 (sv)
ES (1) ES2122253T3 (sv)
FI (1) FI945581A (sv)
GB (1) GB9306886D0 (sv)
HU (1) HUT68256A (sv)
IL (1) IL108969A (sv)
NZ (1) NZ262907A (sv)
PL (1) PL306537A1 (sv)
RU (1) RU94046141A (sv)
WO (1) WO1994022808A1 (sv)
ZA (1) ZA941963B (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9515412D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
GB9706730D0 (en) * 1997-04-03 1997-05-21 Pharmacia & Upjohn Spa 2-[(3-substituted)-5-Isoxazolymethylaminojalkanamid derivatives
US6479484B1 (en) * 1997-11-21 2002-11-12 Euro-Celtique S.A. Substituted 2-aminoacetamides and the use thereof
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
US6281211B1 (en) 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
DE60022333T2 (de) * 1999-04-09 2006-07-06 Euro-Celtique S.A. Natrium kanalblocker zusammensetzungen und deren verwendung
ATE317280T1 (de) 2001-09-03 2006-02-15 Newron Pharm Spa Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung
US6667327B2 (en) 2002-02-04 2003-12-23 Hoffmann-La Roche Inc. Pyridine amido derivatives
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
AR044007A1 (es) 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
EP1524265A1 (en) * 2003-10-15 2005-04-20 Newron Pharmaceuticals S.p.A. Prolinamide derivatives as sodium and/or calcium channel blockers or selective MAO-B inhibitors
MXPA06004307A (es) * 2003-10-23 2006-06-05 Hoffmann La Roche Derivados de benzazepina como inhibidores de mao-b.
EP1588704A1 (en) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
CN101018546B (zh) * 2004-09-10 2013-06-12 纽朗制药有限公司 作为钠和/或钙通道选择性调节剂的(卤代苄氧基)苄氨基-丙酰胺类
EP1870097A1 (en) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
US4049663A (en) * 1972-06-06 1977-09-20 Allen & Hanburys Limited Ethylene diamine derivatives
DE3010599A1 (de) * 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4728668A (en) * 1985-04-16 1988-03-01 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4725619A (en) * 1985-04-16 1988-02-16 Usv Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4839369A (en) * 1985-04-16 1989-06-13 Rorer Pharmaceutical Corporation Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4631287A (en) * 1985-04-16 1986-12-23 Usv Pharmaceutical Corp. Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation

Also Published As

Publication number Publication date
GB9306886D0 (en) 1993-05-26
KR950701904A (ko) 1995-05-17
IL108969A (en) 1998-10-30
ZA941963B (en) 1994-10-19
DE69412016D1 (de) 1998-09-03
CA2135783A1 (en) 1994-10-13
CN1104017A (zh) 1995-06-21
RU94046141A (ru) 1996-09-27
NZ262907A (en) 1996-02-27
EP0643688B1 (en) 1998-07-29
ES2122253T3 (es) 1998-12-16
ATE168991T1 (de) 1998-08-15
FI945581A (sv) 1994-11-28
AU6284294A (en) 1994-10-24
CA2135783C (en) 2005-06-07
IL108969A0 (en) 1994-06-24
JP3542599B2 (ja) 2004-07-14
DE69412016T2 (de) 1999-02-11
WO1994022808A1 (en) 1994-10-13
HUT68256A (en) 1995-06-28
EP0643688A1 (en) 1995-03-22
CN1035938C (zh) 1997-09-24
JPH07507814A (ja) 1995-08-31
PL306537A1 (en) 1995-04-03
US5446066A (en) 1995-08-29
AU667164B2 (en) 1996-03-07

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Legal Events

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Owner name: PHARMACIA & UPJOHN S.P.A.