TR199900842A2 - Sübstitüe edilmis trisiklik bilesikler. - Google Patents
Sübstitüe edilmis trisiklik bilesikler.Info
- Publication number
- TR199900842A2 TR199900842A2 TR1999/00842A TR9900842A TR199900842A2 TR 199900842 A2 TR199900842 A2 TR 199900842A2 TR 1999/00842 A TR1999/00842 A TR 1999/00842A TR 9900842 A TR9900842 A TR 9900842A TR 199900842 A2 TR199900842 A2 TR 199900842A2
- Authority
- TR
- Turkey
- Prior art keywords
- ikler
- edilmi
- bstit
- tricyclic
- bile
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
Abstract
Yeni bir trisiklikler sinifi yani sira bu gibi bilesiklerin, septik sok gibi durumlari tedavi etmek üzere, sPLA2 araciligi ile meydana gelen yag asidi tahliyesini engellemek için kullanimlari açiklanmistir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6216598A | 1998-04-17 | 1998-04-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199900842A2 true TR199900842A2 (tr) | 2000-09-21 |
Family
ID=22040624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1999/00842A TR199900842A2 (tr) | 1998-04-17 | 1999-04-16 | Sübstitüe edilmis trisiklik bilesikler. |
Country Status (27)
Country | Link |
---|---|
EP (2) | EP1156050B1 (tr) |
JP (1) | JP4435325B2 (tr) |
KR (1) | KR19990083234A (tr) |
CN (1) | CN1235968A (tr) |
AR (1) | AR018185A1 (tr) |
AT (2) | ATE254128T1 (tr) |
AU (1) | AU757454B2 (tr) |
BR (1) | BR9901275A (tr) |
CA (1) | CA2269256A1 (tr) |
CO (1) | CO5080728A1 (tr) |
CZ (1) | CZ137199A3 (tr) |
DE (2) | DE69914951T2 (tr) |
EA (1) | EA003129B1 (tr) |
ES (2) | ES2210979T3 (tr) |
HU (1) | HUP9901219A1 (tr) |
ID (1) | ID23219A (tr) |
IL (1) | IL129484A0 (tr) |
NO (1) | NO991823L (tr) |
NZ (1) | NZ335252A (tr) |
PE (1) | PE20000472A1 (tr) |
PL (1) | PL332564A1 (tr) |
SG (1) | SG106035A1 (tr) |
SV (1) | SV1999000052A (tr) |
TR (1) | TR199900842A2 (tr) |
TW (1) | TW555760B (tr) |
YU (1) | YU19099A (tr) |
ZA (1) | ZA992773B (tr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1011670A4 (en) * | 1997-08-28 | 2004-10-27 | Lilly Co Eli | PROCESS FOR TREATING NON-RHUMATOID POLYARTHRITIS |
WO2001074817A1 (fr) * | 2000-03-30 | 2001-10-11 | Yamanouchi Pharmaceutical Co., Ltd. | Derives d'hydrazide |
WO2002005796A2 (en) * | 2000-07-14 | 2002-01-24 | Eli Lilly And Company | Use of a spla2 inhibitor for the treatment of sepsis |
ATE329905T1 (de) * | 2000-12-18 | 2006-07-15 | Lilly Co Eli | Tetracyclische derivate als spla2 inhibitoren |
JP2004525154A (ja) * | 2001-03-28 | 2004-08-19 | イーライ・リリー・アンド・カンパニー | sPLA2インヒビターとしての置換カルバゾール |
WO2003014082A1 (en) * | 2001-08-09 | 2003-02-20 | Eli Lilly And Company | Cyclopenta ` b ! indole derivatives as spla2 inhibitors |
WO2003016277A1 (en) * | 2001-08-09 | 2003-02-27 | Eli Lilly And Company | Cyclohept`b!indole derivatives as spla2 inhibitors |
US6992100B2 (en) | 2001-12-06 | 2006-01-31 | Eli Lilly And Company | sPLA2 inhibitors |
US7608626B2 (en) | 2004-11-01 | 2009-10-27 | Wyeth | Substituted indolizines and derivatives as CNS agents |
AU2009204048B2 (en) | 2008-01-11 | 2013-08-01 | Albany Molecular Research, Inc. | (1-azinone) -substituted pyridoindoles as MCH antagonists |
WO2011003021A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
US8993765B2 (en) | 2010-12-21 | 2015-03-31 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof |
EP2697223B1 (en) * | 2011-04-14 | 2016-07-13 | Actelion Pharmaceuticals Ltd. | 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators |
DK2825541T3 (en) | 2012-03-16 | 2016-10-03 | Vitae Pharmaceuticals Inc | LIVER-X-receptor modulators |
BR112014022780A8 (pt) | 2012-03-16 | 2021-06-15 | Vitae Pharmaceuticals Inc | composto modulador de receptor de fígado x, composição farmacêutica que o compreende e seu uso |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3979391A (en) * | 1972-11-22 | 1976-09-07 | Sterling Drug Inc. | 1,2,3,4-Tetrahydrocarbazoles |
PT95692A (pt) * | 1989-10-27 | 1991-09-13 | American Home Prod | Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase |
IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
IL109309A (en) * | 1993-04-16 | 2000-06-29 | Lilly Co Eli | 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them |
WO1996003383A1 (en) * | 1994-07-21 | 1996-02-08 | Eli Lilly And Company | INDOLIZINE sPLA2 INHIBITORS |
ATE203744T1 (de) * | 1995-12-13 | 2001-08-15 | Lilly Co Eli | Naphthyl-acetamide als spla2-inhibitoren |
JP2001503055A (ja) * | 1996-10-30 | 2001-03-06 | イーライ・リリー・アンド・カンパニー | 置換三環化合物群 |
JP2001517707A (ja) * | 1997-09-26 | 2001-10-09 | イーライ・リリー・アンド・カンパニー | 嚢胞性繊維症の処置方法 |
CA2310250A1 (en) * | 1997-11-14 | 1999-05-27 | August Masaru Watanabe | Treatment for alzheimer's disease |
-
1999
- 1999-04-15 IL IL12948499A patent/IL129484A0/xx unknown
- 1999-04-15 ID IDP990342D patent/ID23219A/id unknown
- 1999-04-16 EA EA199900304A patent/EA003129B1/ru not_active IP Right Cessation
- 1999-04-16 NO NO991823A patent/NO991823L/no not_active Application Discontinuation
- 1999-04-16 AT AT99302969T patent/ATE254128T1/de not_active IP Right Cessation
- 1999-04-16 EP EP01203116A patent/EP1156050B1/en not_active Expired - Lifetime
- 1999-04-16 CN CN99108097A patent/CN1235968A/zh active Pending
- 1999-04-16 TW TW088106131A patent/TW555760B/zh not_active IP Right Cessation
- 1999-04-16 YU YU19099A patent/YU19099A/sh unknown
- 1999-04-16 DE DE69914951T patent/DE69914951T2/de not_active Expired - Fee Related
- 1999-04-16 ES ES99302969T patent/ES2210979T3/es not_active Expired - Lifetime
- 1999-04-16 AT AT01203116T patent/ATE259818T1/de not_active IP Right Cessation
- 1999-04-16 JP JP10965699A patent/JP4435325B2/ja not_active Expired - Fee Related
- 1999-04-16 KR KR1019990013439A patent/KR19990083234A/ko not_active Application Discontinuation
- 1999-04-16 SV SV1999000052A patent/SV1999000052A/es not_active Application Discontinuation
- 1999-04-16 CZ CZ991371A patent/CZ137199A3/cs unknown
- 1999-04-16 SG SG9901844A patent/SG106035A1/en unknown
- 1999-04-16 TR TR1999/00842A patent/TR199900842A2/tr unknown
- 1999-04-16 AR ARP990101769A patent/AR018185A1/es not_active Application Discontinuation
- 1999-04-16 PL PL99332564A patent/PL332564A1/xx not_active Application Discontinuation
- 1999-04-16 CA CA002269256A patent/CA2269256A1/en not_active Abandoned
- 1999-04-16 ES ES01203116T patent/ES2213668T3/es not_active Expired - Lifetime
- 1999-04-16 CO CO99022891A patent/CO5080728A1/es unknown
- 1999-04-16 EP EP99302969A patent/EP0950661B1/en not_active Expired - Lifetime
- 1999-04-16 DE DE69912670T patent/DE69912670T2/de not_active Expired - Fee Related
- 1999-04-16 NZ NZ335252A patent/NZ335252A/xx unknown
- 1999-04-16 ZA ZA9902773A patent/ZA992773B/xx unknown
- 1999-04-16 BR BR9901275-8A patent/BR9901275A/pt not_active IP Right Cessation
- 1999-04-16 AU AU23818/99A patent/AU757454B2/en not_active Ceased
- 1999-04-16 PE PE1999000321A patent/PE20000472A1/es not_active Application Discontinuation
- 1999-04-16 HU HU9901219A patent/HUP9901219A1/hu unknown
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