GT199900011A - Nuevos derivados del acido dihidroxihexanoico - Google Patents

Nuevos derivados del acido dihidroxihexanoico

Info

Publication number
GT199900011A
GT199900011A GT199900011A GT199900011A GT199900011A GT 199900011 A GT199900011 A GT 199900011A GT 199900011 A GT199900011 A GT 199900011A GT 199900011 A GT199900011 A GT 199900011A GT 199900011 A GT199900011 A GT 199900011A
Authority
GT
Guatemala
Prior art keywords
acid
new derivatives
dihydroxyhexanic
fòrmula
dihydrohexanoic
Prior art date
Application number
GT199900011A
Other languages
English (en)
Inventor
John Charles Kath
Matthew Frank Brown
Christopher Stanley Poss
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199900011A publication Critical patent/GT199900011A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

LA PRESENTE INVENCIÒN SE REFIERE A NUEVOS DERIVADOS DEL ÀCIDO DIHIDROHEXANOICO SIMBOLIZADOS GENÈRICAMENTE POR LA FÒRMULA (I), DONDE LOS SUSTITUYENTES R REPRESENTAN DIFERENTES POSIBILIDADES DE GRUPO FUNCIONAL DESCRITOS EN EL DOCUMENTO, SE DESCRIBE TAMBIEN PROCEDIMIENTOS PARA SU USO Y COMPOSICIONES FARMACEÙTICAS QUE LOS CONTIENEN.
GT199900011A 1998-02-05 1999-01-27 Nuevos derivados del acido dihidroxihexanoico GT199900011A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7380198P 1998-02-05 1998-02-05

Publications (1)

Publication Number Publication Date
GT199900011A true GT199900011A (es) 2000-07-20

Family

ID=22115885

Family Applications (1)

Application Number Title Priority Date Filing Date
GT199900011A GT199900011A (es) 1998-02-05 1999-01-27 Nuevos derivados del acido dihidroxihexanoico

Country Status (37)

Country Link
EP (1) EP1051405B1 (es)
JP (1) JP3693916B2 (es)
KR (1) KR100385529B1 (es)
CN (1) CN1177834C (es)
AP (1) AP992A (es)
AR (1) AR016175A1 (es)
AT (1) ATE337307T1 (es)
AU (1) AU752407B2 (es)
BG (1) BG104726A (es)
BR (1) BR9907655A (es)
CA (1) CA2320388C (es)
DE (1) DE69932920T2 (es)
DZ (1) DZ2717A1 (es)
EA (1) EA003137B1 (es)
ES (1) ES2268847T3 (es)
GT (1) GT199900011A (es)
HK (1) HK1034969A1 (es)
HR (1) HRP20000529B1 (es)
HU (1) HUP0100832A3 (es)
IL (1) IL137330A0 (es)
IS (1) IS5562A (es)
MA (1) MA26603A1 (es)
MY (1) MY133125A (es)
NO (1) NO20003965D0 (es)
NZ (1) NZ505724A (es)
OA (1) OA11448A (es)
PA (1) PA8467301A1 (es)
PE (1) PE20000243A1 (es)
PL (1) PL342817A1 (es)
SK (1) SK11262000A3 (es)
TN (1) TNSN99013A1 (es)
TR (1) TR200002248T2 (es)
TW (1) TW470744B (es)
UA (1) UA57824C2 (es)
WO (1) WO1999040061A2 (es)
YU (1) YU47100A (es)
ZA (1) ZA99873B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002535358A (ja) * 1999-01-29 2002-10-22 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 移植片拒絶反応及び虚血−再灌流障害の予防方法
BR0013469B1 (pt) * 1999-08-20 2011-01-25 amidas aromáticas heterocìclicas fungicidas, composição fungicida compreendendo as mesmas, bem como método para o controle ou a prevenção de infestação fúngica.
OA12174A (en) * 2000-02-04 2006-05-09 Pfizer Prod Inc Heterocyclic amide derivatives.
EP1498417A1 (en) * 2000-02-04 2005-01-19 Pfizer Products Inc. Heterocyclic amide derivatives
US6740636B2 (en) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
US6746856B2 (en) 2000-08-09 2004-06-08 Pfizer Inc. Microbial conversion of bicyclic heteroaromatic compounds
ATE444060T1 (de) 2001-06-22 2009-10-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren
EP1269994A3 (en) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
TNSN03138A1 (en) 2001-06-22 2005-12-23 Pfizer Prod Inc PHARMACEUTICAL COMPOSITIONS OF ADSORBATES OF AN AMORPHOUS MEDICINAL PRODUCT
DE10152351B4 (de) * 2001-10-18 2005-09-22 Schering Ag Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
CA2474838C (en) 2002-02-01 2009-01-06 Pfizer Products Inc. Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials
BR0309932A (pt) * 2002-05-14 2005-02-09 Pfizer Prod Inc Métodos para a fabricação de derivados de diidro-furan-2-ona
PL373961A1 (en) * 2002-05-14 2005-09-19 Pfizer Products Inc. Dihydroxyhexanoic acid derivatives, their intermediates, and methods of making
RU2005103625A (ru) 2002-08-12 2005-08-20 Пфайзер Продактс Инк. (Us) Фармацевтические композиции полуупорядоченных лекарств и полимеров
EP1539715A1 (en) * 2002-08-12 2005-06-15 Pfizer Products Inc. Crystal forms of quinoxaline-2-carboxylic acid 4-carbamoyl- 1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyl-octyl -amide
US20040087571A1 (en) * 2002-10-30 2004-05-06 Pfizer Inc Methods of using CCR1 antagonists as immunomodulatory agents
US20040097554A1 (en) * 2002-10-30 2004-05-20 Pfizer Inc Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents
BRPI0413277A (pt) 2003-08-04 2006-10-10 Pfizer Prod Inc composições farmacêuticas de adsorvatos de medicamentos amorfos e materiais que formam microfases lipofìlicas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923864A (en) * 1987-12-15 1990-05-08 Pfizer Inc. Certain heterocyclic-hexanamides useful for treating hypertension
PT708085E (pt) * 1994-10-19 2002-11-29 Novartis Ag Eteres antivirais de isosteros de substrato de aspartato protease
DE19708106A1 (de) * 1997-02-28 1998-09-03 Bosch Gmbh Robert Einrichtung und Verfahren zur Information über Verkehrsstörungen

Also Published As

Publication number Publication date
EA003137B1 (ru) 2003-02-27
SK11262000A3 (sk) 2001-01-18
AU1778999A (en) 1999-08-23
PA8467301A1 (es) 2000-05-24
BR9907655A (pt) 2000-10-24
CN1177834C (zh) 2004-12-01
BG104726A (en) 2001-04-30
MY133125A (en) 2007-10-31
UA57824C2 (uk) 2003-07-15
AU752407B2 (en) 2002-09-19
HUP0100832A3 (en) 2002-03-28
TW470744B (en) 2002-01-01
HRP20000529A2 (en) 2001-08-31
IS5562A (is) 2000-07-14
KR20010040684A (ko) 2001-05-15
CN1290255A (zh) 2001-04-04
HRP20000529B1 (en) 2004-12-31
WO1999040061A3 (en) 1999-10-21
WO1999040061A2 (en) 1999-08-12
TR200002248T2 (tr) 2000-12-21
OA11448A (en) 2003-11-18
JP3693916B2 (ja) 2005-09-14
AP9901457A0 (en) 1999-03-31
MA26603A1 (fr) 2004-12-20
CA2320388C (en) 2005-05-03
DZ2717A1 (fr) 2003-09-01
HUP0100832A2 (hu) 2002-02-28
ES2268847T3 (es) 2007-03-16
TNSN99013A1 (fr) 2005-11-10
NO20003965L (es) 2000-10-03
DE69932920T2 (de) 2007-02-08
YU47100A (sh) 2002-11-15
EA200000741A1 (ru) 2001-02-26
AR016175A1 (es) 2001-06-20
PL342817A1 (en) 2001-07-02
ZA99873B (en) 2000-08-04
EP1051405A2 (en) 2000-11-15
KR100385529B1 (ko) 2003-05-27
CA2320388A1 (en) 1999-08-12
IL137330A0 (en) 2001-07-24
DE69932920D1 (de) 2006-10-05
NO20003965D0 (no) 2000-08-04
AP992A (en) 2001-08-06
NZ505724A (en) 2003-02-28
ATE337307T1 (de) 2006-09-15
PE20000243A1 (es) 2000-04-07
JP2002502839A (ja) 2002-01-29
EP1051405B1 (en) 2006-08-23
HK1034969A1 (en) 2001-11-09

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