ES2056105T3 - Di-t-butilfenoles sustituidos. - Google Patents
Di-t-butilfenoles sustituidos.Info
- Publication number
- ES2056105T3 ES2056105T3 ES88303037T ES88303037T ES2056105T3 ES 2056105 T3 ES2056105 T3 ES 2056105T3 ES 88303037 T ES88303037 T ES 88303037T ES 88303037 T ES88303037 T ES 88303037T ES 2056105 T3 ES2056105 T3 ES 2056105T3
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- butilfenoles
- group
- compounds
- butylphenoles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/75—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LOS NUEVOS COMPUESTOS QUE SON 2,6-DI-TER-BUTILFENOLES SUSTITUIDOS EN LA POSICION 4 POR UN GRUPO CARBAMILO O ACILAMINO, SUSTITUIDOS A SU VEZ POR UN GRUPO QUE INCLUYE UN SUSTIUYENTE ACIDO, SON UTILES COMO INHIBIDORES DE LA BIOSINTESIS DE LEUCOTRIENOS Y COMO AGENTES ANTIALERGICOS. SE PRESENTAN TAMBIEN METODOS FARMACOLOGICOS PARA EL EMPLEO DE DICHOS COMPUESTOS Y PRODUCTOS INTERMEDIOS DE SINTESIS PARA PREPARARLOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3453787A | 1987-04-06 | 1987-04-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2056105T3 true ES2056105T3 (es) | 1994-10-01 |
Family
ID=21877034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88303037T Expired - Lifetime ES2056105T3 (es) | 1987-04-06 | 1988-04-06 | Di-t-butilfenoles sustituidos. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0286364B1 (es) |
JP (1) | JP2514999B2 (es) |
KR (1) | KR960009115B1 (es) |
AU (1) | AU615182B2 (es) |
CA (1) | CA1322374C (es) |
DE (1) | DE3850598T2 (es) |
DK (1) | DK177088A (es) |
ES (1) | ES2056105T3 (es) |
IL (1) | IL85896A (es) |
NO (1) | NO178619C (es) |
NZ (1) | NZ224079A (es) |
ZA (1) | ZA882251B (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5264578A (en) | 1987-03-20 | 1993-11-23 | Allergan, Inc. | Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity |
NZ226621A (en) * | 1987-11-13 | 1991-12-23 | Riker Laboratories Inc | Di-tert butyl phenols substituted by alkoxy, benzyloxy, or benzylthio groups; pharmaceutical compositions containing them |
US5047555A (en) * | 1988-12-13 | 1991-09-10 | Tanabe Seiyaku Co., Ltd. | 4-aminophenol derivatives and processes for preparing the same |
IT1232252B (it) * | 1989-02-22 | 1992-01-28 | Rotta Research Lab | Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione |
IT1256870B (it) * | 1992-02-13 | 1995-12-27 | Rotta Research Lab | Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva |
US5534641A (en) | 1994-12-29 | 1996-07-09 | Allergan | Acetylenes disubstituted with 2-tetrahydropyranoxyaryl and aryl or heteroaryl groups having retinoid-like biological activity |
US5648514A (en) | 1994-12-29 | 1997-07-15 | Allergan | Substituted acetylenes having retinoid-like biological activity |
US5675033A (en) | 1995-06-06 | 1997-10-07 | Allergan | 2,4-pentadienoic acid derivatives having retinoid-like biological activity |
US5917082A (en) | 1995-06-06 | 1999-06-29 | Allergan Sales, Inc. | 2,4-pentadienoic acid derivatives having retinoid-like biological activity |
US6008204A (en) | 1995-09-01 | 1999-12-28 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
US5958954A (en) | 1995-09-01 | 1999-09-28 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
US5952345A (en) | 1995-09-01 | 1999-09-14 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
US6218128B1 (en) | 1997-09-12 | 2001-04-17 | Allergan Sales, Inc. | Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities |
US5675024A (en) | 1995-11-22 | 1997-10-07 | Allergan | Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity |
US5663357A (en) | 1995-11-22 | 1997-09-02 | Allergan | Substituted heteroarylamides having retinoid-like biological activity |
US5763635A (en) | 1996-06-21 | 1998-06-09 | Allergan | Tetrahydronaphthalene derivatives substituted in the 8 position with alkyhidene groups having retinoid and/or retinoid antagonist-like biological activity |
US6555690B2 (en) | 1996-06-21 | 2003-04-29 | Allergan, Inc. | Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
US5773594A (en) | 1996-06-21 | 1998-06-30 | Allergan | Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
US5741896A (en) | 1996-06-21 | 1998-04-21 | Allergan | O- or S- substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
US5728846A (en) | 1996-12-12 | 1998-03-17 | Allergan | Benzo 1,2-g!-chrom-3-ene and benzo 1,2-g!-thiochrom-3-ene derivatives |
US5760276A (en) * | 1997-03-06 | 1998-06-02 | Allergan | Aryl-and heteroarylcyclohexenyl substituted alkenes having retinoid agonist, antagonist or inverse agonist type biological activity |
US6037488A (en) | 1997-04-19 | 2000-03-14 | Allergan Sales, Inc. | Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity |
US5919970A (en) | 1997-04-24 | 1999-07-06 | Allergan Sales, Inc. | Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity |
WO2000061182A2 (en) * | 1999-04-14 | 2000-10-19 | Allergan Sales, Inc. | Methods and compositions for the treatment and prevention of lung disease involving a selective rar-alpha agonist |
US6369261B1 (en) | 2000-08-29 | 2002-04-09 | Allergan Sales, Inc. | Compounds having activity as inhibitors of cytochrome P450RAI |
US6387951B1 (en) | 2000-08-29 | 2002-05-14 | Allergan Sales, Inc. | Compounds having activity as inhibitors of cytochrome P450RAI |
US6313107B1 (en) | 2000-08-29 | 2001-11-06 | Allergan Sales, Inc. | Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI |
PA8578101A1 (es) * | 2002-08-13 | 2004-05-07 | Warner Lambert Co | Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz |
BR112014016804A8 (pt) | 2012-01-06 | 2017-07-04 | Univ California | composições, métodos de uso e métodos de tratamento |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1453972A (fr) * | 1965-08-12 | 1966-07-22 | Rhone Poulenc Sa | Procédé de stabilisation des polyoléfines et nouveaux agents de stabilisation |
FR2035771A1 (en) * | 1969-03-14 | 1970-12-24 | Aries Robert | Salicylaminophenols having analgesic antipy - etic and antiinflammatory activity |
DE2021133A1 (de) * | 1969-04-30 | 1970-11-12 | Geigy Ag J R | Aroylamidoalkylphenole |
US4128664A (en) * | 1977-05-16 | 1978-12-05 | Riker Laboratories, Inc. | Substituted benzamides as anti-inflammatory agents |
JPS6056130B2 (ja) * | 1978-03-20 | 1985-12-09 | 久光製薬株式会社 | 新規なサリチル酸誘導体 |
DE3521558A1 (de) * | 1985-06-15 | 1986-12-18 | Basf Ag, 6700 Ludwigshafen | 3-t-butyl-4-hydroxiphenylpropionsaeureaminoalkylamidderivate und damit stabilisiertes organisches material |
ZA865090B (en) * | 1985-07-22 | 1988-02-24 | Riker Laboratories Inc | Substituted di-t-butylphenols |
ZA865091B (en) * | 1985-07-22 | 1988-02-24 | Riker Laboratories Inc | Substituted di-t-butylphenols |
US4714776A (en) * | 1985-07-22 | 1987-12-22 | Riker Laboratories, Inc. | Antiallergic agents |
US4667069A (en) * | 1985-08-16 | 1987-05-19 | Ranco Incorporated | Multiple disc pressure responsive control device |
-
1988
- 1988-03-29 IL IL85896A patent/IL85896A/xx not_active IP Right Cessation
- 1988-03-29 ZA ZA882251A patent/ZA882251B/xx unknown
- 1988-03-30 DK DK177088A patent/DK177088A/da not_active Application Discontinuation
- 1988-03-30 NZ NZ224079A patent/NZ224079A/en unknown
- 1988-03-30 CA CA000562945A patent/CA1322374C/en not_active Expired - Fee Related
- 1988-03-31 AU AU14073/88A patent/AU615182B2/en not_active Ceased
- 1988-04-06 ES ES88303037T patent/ES2056105T3/es not_active Expired - Lifetime
- 1988-04-06 NO NO881482A patent/NO178619C/no unknown
- 1988-04-06 DE DE3850598T patent/DE3850598T2/de not_active Expired - Fee Related
- 1988-04-06 JP JP63084984A patent/JP2514999B2/ja not_active Expired - Lifetime
- 1988-04-06 KR KR88003803A patent/KR960009115B1/ko not_active IP Right Cessation
- 1988-04-06 EP EP88303037A patent/EP0286364B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO178619C (no) | 1996-05-02 |
JPH01261379A (ja) | 1989-10-18 |
AU615182B2 (en) | 1991-09-26 |
JP2514999B2 (ja) | 1996-07-10 |
NO881482D0 (no) | 1988-04-06 |
NO178619B (no) | 1996-01-22 |
EP0286364A2 (en) | 1988-10-12 |
ZA882251B (en) | 1989-11-29 |
KR960009115B1 (en) | 1996-07-13 |
AU1407388A (en) | 1988-10-06 |
NZ224079A (en) | 1990-11-27 |
DE3850598D1 (de) | 1994-08-18 |
EP0286364A3 (en) | 1990-08-01 |
IL85896A (en) | 1993-01-14 |
KR880012534A (ko) | 1988-11-28 |
DE3850598T2 (de) | 1995-01-05 |
CA1322374C (en) | 1993-09-21 |
EP0286364B1 (en) | 1994-07-13 |
IL85896A0 (en) | 1988-09-30 |
NO881482L (no) | 1988-10-07 |
DK177088A (da) | 1989-01-12 |
DK177088D0 (da) | 1988-03-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2056105T3 (es) | Di-t-butilfenoles sustituidos. | |
ES2045180T3 (es) | Nuevo procedimiento para la obtencion de 4-aciloxi-3-hidroxietil-azetidinonas. | |
ES2059377T3 (es) | Pirazoles 1,5-diaril-3-sustituidos farmacologicamente activos y procedimiento para sintetizar los mismos. | |
ES2058185T3 (es) | Derivados de camptotecina y procedimiento para su preparacion. | |
IT1206078B (it) | Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico | |
BG45701A3 (en) | Method for preparing of alpha- heterocyclic substituted tolunitriles | |
ES2053778T3 (es) | Procedimiento para la obtencion de derivados del tiazol. | |
ES2055035T3 (es) | Un proceso para la preparacion de un glicosido de antraciclina. | |
ES2072263T3 (es) | Derivados de 4-aminopiridina. | |
ES2051862T3 (es) | Un metodo para producir un medicamento que tiene un efecto catartico. | |
ES2045009T3 (es) | El acido taurohyodesoxicolico para la terapia de calculosis del tracto biliar y de la dispepsia biliar. | |
IT1164821B (it) | Benzammidi eterocicliche sostituite procedimento per la loro produzione e loro impiego come modificatori di comportamento | |
ES2058191T3 (es) | Acidos 2-fenil-4-quinolincarboxilicos substituidos. | |
GT199900011A (es) | Nuevos derivados del acido dihidroxihexanoico | |
BG40481A3 (en) | Method for preparing phenetanolamines | |
BG41126A3 (en) | Method for preparing benzamides | |
BG28568A3 (bg) | Метод за получаване на естери на оксаловата киселина | |
ES2037763T3 (es) | Metodo para preparar compuestos no naturales afines a la ceramida. | |
MX9304424A (es) | Bencimidazoles, medicamentos que contienen estos compuestos y procedimiento para su preparacion. | |
BG35746A3 (en) | Method for preparing 1- cyclohexenylmethylpyrolidines | |
BG43867A3 (en) | Method for preparing of 6- alpha- methylcorticoids | |
HU9203838D0 (en) | Method for producing isohirudin of improved stability | |
BG44203A3 (en) | Method for preparing of 2- oxyindol- 1- carboxamides | |
ES2058269T3 (es) | Di-t-butilfenil-alquil y -bencil-eteres. | |
ES2184150T3 (es) | Uso de derivados de los acidos 7-(1-aminometil-2-oxa-7-aza-biciclo(3.3.0)oct-7il)-quinoloncarboxilico y -naftiridoncarboxilico para el tratamiento de infecciones causadas por helicobacter pylori y de las afecciones gastroduodenales asociadas con ellas. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 286364 Country of ref document: ES |