IT1256870B - Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva - Google Patents
Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettivaInfo
- Publication number
- IT1256870B IT1256870B ITTO920114A ITTO920114A IT1256870B IT 1256870 B IT1256870 B IT 1256870B IT TO920114 A ITTO920114 A IT TO920114A IT TO920114 A ITTO920114 A IT TO920114A IT 1256870 B IT1256870 B IT 1256870B
- Authority
- IT
- Italy
- Prior art keywords
- antiallergic
- bis
- ring
- tetrazole derivatives
- cytoprotective activity
- Prior art date
Links
- YTNLBRCAVHCUPD-UHFFFAOYSA-N 5-(1$l^{2},2,3,4-tetrazol-5-yl)-1$l^{2},2,3,4-tetrazole Chemical class [N]1N=NN=C1C1=NN=N[N]1 YTNLBRCAVHCUPD-UHFFFAOYSA-N 0.000 title 1
- 230000003266 anti-allergic effect Effects 0.000 title 1
- 230000001120 cytoprotective effect Effects 0.000 title 1
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical group NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 abstract 2
- -1 1H-tetrazol-5yl Chemical group 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Abstract
Composti N-fenil-benzamidici ed N-piridinil-benzamidici farmaceuticamente attivi aventi formula (I): (FORMULA I) dove A è l'anello benzenico oppure l'anello piridinico ed R1 e R2 sono entrambi il gruppo (1H-tetrazol-5yl) ed in cui se R1 è situato nelle posizioni orto oppure meta al gruppo benzamidico, R2 è posto in orto, meta oppure para dell'anello A, mentre se R1 è situato in posizione para al gruppo benzamidico, R2 può essere in posizione orto oppure meta dell'anello A ed i loro sali farmaceuticamente accettabili.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITTO920114A IT1256870B (it) | 1992-02-13 | 1992-02-13 | Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva |
PCT/EP1993/000326 WO1993016053A1 (en) | 1992-02-13 | 1993-02-11 | Novel bistetrazol derivatives having an antiallergic and cytoprotective activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITTO920114A IT1256870B (it) | 1992-02-13 | 1992-02-13 | Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva |
Publications (3)
Publication Number | Publication Date |
---|---|
ITTO920114A0 ITTO920114A0 (it) | 1992-02-13 |
ITTO920114A1 ITTO920114A1 (it) | 1993-08-13 |
IT1256870B true IT1256870B (it) | 1995-12-27 |
Family
ID=11410046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITTO920114A IT1256870B (it) | 1992-02-13 | 1992-02-13 | Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva |
Country Status (2)
Country | Link |
---|---|
IT (1) | IT1256870B (it) |
WO (1) | WO1993016053A1 (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4798410B2 (ja) * | 1999-06-25 | 2011-10-19 | 日本農薬株式会社 | ベンズアミド誘導体及び農園芸用殺虫剤並びにその使用方法 |
KR100429442B1 (ko) * | 1999-06-25 | 2004-05-03 | 니혼노야쿠가부시키가이샤 | 벤즈아미드 유도체, 농원예용 살충제 및 그의 사용 방법 |
MY120647A (en) * | 2000-12-20 | 2005-11-30 | Nihon Nohyaku Co Ltd | Benzamide derivatives and agricultural and horticultural insecticides and method for using thereof. |
ATE316085T1 (de) | 2001-08-15 | 2006-02-15 | Du Pont | Mit heterocyclen ortho-substituierte aryl amide zur bekämpfung wirbelloser schädlinge |
US7078423B2 (en) | 2002-07-18 | 2006-07-18 | Inotek Pharmaceuticals Corporation | 5-Aryltetrazole compounds, compositions thereof, and uses therefor |
US7087631B2 (en) | 2002-07-18 | 2006-08-08 | Inotek Pharmaceuticals Corporation | Aryltetrazole compounds, and compositions thereof |
US7037927B2 (en) | 2003-10-16 | 2006-05-02 | Abbott Laboratories | Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor |
CN104159587A (zh) | 2012-01-06 | 2014-11-19 | 南佛罗里达大学 | 组合物、使用方法、以及治疗方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4994479A (en) * | 1985-04-03 | 1991-02-19 | Yamanouchi Pharmaceutical Co., Ltd. | Phenylene derivatives and anti-allergic use thereof |
ZA882251B (en) * | 1987-04-06 | 1989-11-29 | Riker Laboratories Inc | Substituted di-t-butylphenols |
IT1232252B (it) * | 1989-02-22 | 1992-01-28 | Rotta Research Lab | Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione |
-
1992
- 1992-02-13 IT ITTO920114A patent/IT1256870B/it active IP Right Grant
-
1993
- 1993-02-11 WO PCT/EP1993/000326 patent/WO1993016053A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO1993016053A1 (en) | 1993-08-19 |
ITTO920114A0 (it) | 1992-02-13 |
ITTO920114A1 (it) | 1993-08-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19990129 |