TR199800653T1 - Farmasötik anjiyostatik dipeptid kompozisyonlari ve bunlarin kullanilmasina yönelik metodlar. - Google Patents

Farmasötik anjiyostatik dipeptid kompozisyonlari ve bunlarin kullanilmasina yönelik metodlar.

Info

Publication number
TR199800653T1
TR199800653T1 TR1998/00653T TR9800653T TR199800653T1 TR 199800653 T1 TR199800653 T1 TR 199800653T1 TR 1998/00653 T TR1998/00653 T TR 1998/00653T TR 9800653 T TR9800653 T TR 9800653T TR 199800653 T1 TR199800653 T1 TR 199800653T1
Authority
TR
Turkey
Prior art keywords
methods
pharmaceutical
angiostatic
dipeptide
compositions
Prior art date
Application number
TR1998/00653T
Other languages
English (en)
Inventor
R. Green Lawrence
W. Blasecki John
Original Assignee
Cytran, Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytran, Ltd filed Critical Cytran, Ltd
Publication of TR199800653T1 publication Critical patent/TR199800653T1/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Bir kisiye R'-Glu-Trp-R" nün farmasötik bir preparatinin verilmesi sureti ile kiside neovaskülarizasyonun engellenmesine yönelik metodlar tarif edilmektedir.
TR1998/00653T 1995-10-03 1996-10-02 Farmasötik anjiyostatik dipeptid kompozisyonlari ve bunlarin kullanilmasina yönelik metodlar. TR199800653T1 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53870195A 1995-10-03 1995-10-03
US08/614,764 US5902790A (en) 1995-10-03 1996-03-13 Pharmaceutical angiostatic dipeptide compositions and method of use thereof

Publications (1)

Publication Number Publication Date
TR199800653T1 true TR199800653T1 (tr) 1998-06-22

Family

ID=27065900

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00653T TR199800653T1 (tr) 1995-10-03 1996-10-02 Farmasötik anjiyostatik dipeptid kompozisyonlari ve bunlarin kullanilmasina yönelik metodlar.

Country Status (23)

Country Link
US (4) US5902790A (tr)
EP (1) EP0869808B1 (tr)
JP (2) JP3679129B2 (tr)
KR (1) KR100483779B1 (tr)
CN (1) CN1128636C (tr)
AT (1) ATE332702T1 (tr)
AU (1) AU714846B2 (tr)
BR (1) BR9610838A (tr)
CA (1) CA2233457C (tr)
CZ (1) CZ298345B6 (tr)
DE (1) DE69636343T2 (tr)
DK (1) DK0869808T3 (tr)
EA (1) EA001146B1 (tr)
ES (1) ES2268710T3 (tr)
HU (1) HUP9902105A3 (tr)
IL (1) IL123889A0 (tr)
MX (1) MX9802564A (tr)
NO (1) NO326298B1 (tr)
NZ (1) NZ319907A (tr)
PL (1) PL186123B1 (tr)
SK (1) SK283677B6 (tr)
TR (1) TR199800653T1 (tr)
WO (1) WO1997012625A1 (tr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US6060452A (en) * 1996-03-13 2000-05-09 Cytran, Inc. Analogs of L-Glu-L-Trp having pharmacological activity
WO1999051720A2 (en) * 1998-04-03 1999-10-14 Cytran Ltd. Methods for production of therapeutic cytokines
EP1311269B1 (en) 2000-08-04 2012-02-29 DMI Biosciences, Inc. Method of using diketopiperazines and composition containing them
DE10100052A1 (de) * 2001-01-02 2002-07-11 Inst Medizintechnologie Magdeb Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose
US7229969B2 (en) * 2001-01-02 2007-06-12 Imtm Gmbh Combinations of enzyme inhibitors and the use thereof
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
ES2572975T3 (es) 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
WO2005016326A2 (en) * 2003-07-11 2005-02-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
EP1663223B1 (en) 2003-09-17 2014-01-01 The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services Thalidomide analogs as tnf-alpha modulators
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
CA2569204A1 (en) * 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) * 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
UA96980C2 (ru) * 2007-02-13 2011-12-26 Сайклон Фармасютикалс, Инк. Способ уменьшения степени ухудшения состояния, поражения или повреждения слизистой оболочки
CA2579119C (en) 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
UA98508C2 (ru) * 2007-08-23 2012-05-25 Сайклон Фармасьютикалз, Инк. Иммуномодуляторное производное дипептида для лечения рака легких
US8217047B2 (en) 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
DE102008032828A1 (de) * 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
JP2013537195A (ja) 2010-09-07 2013-09-30 ディエムアイ アクイジション コーポレイション 疾患の治療
MX2014003856A (es) 2011-10-10 2015-01-16 Ampio Pharmaceuticals Inc Dispositivos medicos implantables con tolerancia inmune incrementada y metodos para hacerlos e implantarlos.
CN103841987B (zh) 2011-10-10 2015-06-17 安皮奥制药股份有限公司 退行性关节病的治疗
SG10201605205VA (en) 2011-10-28 2016-08-30 Ampio Pharmaceuticals Inc Treatment of rhinitis
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds
CN102631464B (zh) * 2012-05-18 2013-07-31 崔新明 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法
EP2968315B1 (en) 2013-03-15 2020-06-03 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9375478B1 (en) 2015-01-30 2016-06-28 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
JP2020532586A (ja) 2017-08-31 2020-11-12 シンガポール ヘルス サービシーズ プライベート リミテッド 網膜血管性疾患の処置のためのａｎｇｉｏ−３

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997516A (en) * 1974-07-04 1976-12-14 Takeda Chemical Industries, Ltd. Method for protecting guanidino group and restoring the same
US4191753A (en) * 1978-11-06 1980-03-04 University Of Miami Anti-hypertensive peptide analogs
WO1989006134A1 (en) * 1987-12-30 1989-07-13 Vsesojuzny Kardiologichesky Nauchny Tsentr Akademi Pharmaceutical preparation for treating immunodeficiency conditions
US5728680A (en) * 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
SU1642398A1 (ru) * 1988-12-21 1991-04-15 Ростовский медицинский институт Способ лечени синуитов у детей
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
RU1827255C (ru) * 1990-10-22 1993-07-15 Киевский государственный институт усовершенствования врачей Способ лечени туберкулеза легких
JP3068656B2 (ja) * 1991-03-07 2000-07-24 アピ株式会社 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物
AU668088B2 (en) * 1991-04-01 1996-04-26 Cytran Ltd. Pharmaceutical dipeptide compositions and methods of use thereof
RU2014063C1 (ru) * 1991-04-23 1994-06-15 Сочинский научно-исследовательский институт курортологии и физиотерапии Способ лечения подострых воспалительных заболеваний гениталий
DE69230500D1 (de) * 1991-10-28 2000-02-03 Cytran Ltd Pharmazeutische Dipeptid Zusammensetzungen und Verwendungsmethoden.
WO1995003067A1 (en) * 1993-07-21 1995-02-02 Khavinson Vladimir Khatskelevi Pharmaceutical with immunomodulating activity
EP0745091A4 (en) * 1993-09-24 1998-05-20 Univ Southern California USE OF ANGIOTENSIN II ANALOGS IN TISSUE RECOVERY

Also Published As

Publication number Publication date
NO326298B1 (no) 2008-11-03
NZ319907A (en) 2000-09-29
IL123889A0 (en) 1998-10-30
ES2268710T3 (es) 2007-03-16
HUP9902105A2 (hu) 1999-09-28
NO981436L (no) 1998-05-19
DE69636343T2 (de) 2007-07-19
MX9802564A (es) 1998-11-30
CN1198673A (zh) 1998-11-11
JP2005194287A (ja) 2005-07-21
BR9610838A (pt) 1999-12-21
CA2233457C (en) 2004-08-03
SK42398A3 (en) 1998-10-07
US5902790A (en) 1999-05-11
US6911431B1 (en) 2005-06-28
JP3679129B2 (ja) 2005-08-03
ATE332702T1 (de) 2006-08-15
KR100483779B1 (ko) 2007-03-02
US20060094665A1 (en) 2006-05-04
JPH11504943A (ja) 1999-05-11
EA001146B1 (ru) 2000-10-30
KR19990063958A (ko) 1999-07-26
CA2233457A1 (en) 1997-04-10
SK283677B6 (sk) 2003-11-04
EP0869808B1 (en) 2006-07-12
EP0869808A1 (en) 1998-10-14
CZ298345B6 (cs) 2007-09-05
NO981436D0 (no) 1998-03-30
CZ91398A3 (cs) 1998-11-11
WO1997012625A1 (en) 1997-04-10
AU7254096A (en) 1997-04-28
PL186123B1 (pl) 2003-10-31
DK0869808T3 (da) 2006-11-13
AU714846B2 (en) 2000-01-13
EA199800357A1 (ru) 1998-10-29
HUP9902105A3 (en) 2001-02-28
CN1128636C (zh) 2003-11-26
DE69636343D1 (de) 2006-08-24
PL326149A1 (en) 1998-08-31
US6096713A (en) 2000-08-01

Similar Documents

Publication Publication Date Title
TR199800653T1 (tr) Farmasötik anjiyostatik dipeptid kompozisyonlari ve bunlarin kullanilmasina yönelik metodlar.
NO963053L (no) Kosmetiske eller farmasöytiske preparater inneholdende mangiferin eller derivater derav
DE69523438D1 (de) Orale metoprolol-dosisform des typs "einmal täglich"
LU90987I2 (fr) Copaxone et ses dérivés pharmaceutiquement acceptables
MX171191B (es) Composiciones farmaceuticas de glipizida
MX9700081A (es) Composiciones farmaceuticas de tacrina.
TR199802108T2 (tr) Ibandronat içeren oral farmasötik bir formülasyon.
DK0539479T3 (da) Heterocykliske forbindelser
FR2735369B1 (fr) Compositions pharmaceutiques a base de sel de sodium du diclofenac et de thiocolchicoside
TR200001519T2 (tr) İnsanlardaki Spermatozoa'nın konsantrasyonu ve/veya hareket kabiliyetini artırmak için uygulanması gerekli yöntem ve ilaç terkipleri
FI972434A0 (fi) Lamotrigiiniä sisältävä farmaseuttinen koostumus
BR9611571B1 (pt) composiÇço farmacÊutica estÁvel, kit para administraÇço de ngf e produto medicinal.
YU42397A (sh) Korišćenje raloksifena za pripremu leka
IT1244636B (it) Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
ES2062137T3 (es) Utilizacion de 5'-deoxi-5'-metil-tioadenosina, s-adenosilmetionina y sus sales para la preparacion de composiciones farmaceuticas reductoras de seborrea.
ES2124256T3 (es) Arilmorfolina, preparacion y uso.
ES2187489T3 (es) Composiciones farmaceuticas a base de diclofenac.
ITMI932189A1 (it) Composizioni farmaceutiche contenenti n-acetilcarnosina per il trattamento della cataratta
NO950177L (no) Farmakologisk aktive erivater
ES8801267A1 (es) Procedimiento para preparar derivados de isoquinolinona
AR031508A1 (es) Compuesto polisacarido con actividad inmunoestimulante
KR970009798A (ko) 포유동물에서의 유리 라디칼 손상을 감소시키기 위해 철 킬레이트화 화합물을 사용하는 방법
ECSP951595A (es) Derivados de pirrol case ran 4070/101
MX9101421A (es) Composiciones farmaceuticas que comprenden naproxen y sodio de naproxen e hidrocloruro de pseudoefedrina.