DE69523438D1 - Orale metoprolol-dosisform des typs "einmal täglich" - Google Patents

Orale metoprolol-dosisform des typs "einmal täglich"

Info

Publication number
DE69523438D1
DE69523438D1 DE69523438T DE69523438T DE69523438D1 DE 69523438 D1 DE69523438 D1 DE 69523438D1 DE 69523438 T DE69523438 T DE 69523438T DE 69523438 T DE69523438 T DE 69523438T DE 69523438 D1 DE69523438 D1 DE 69523438D1
Authority
DE
Germany
Prior art keywords
metoprolol
day
once
type
dosing form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69523438T
Other languages
English (en)
Other versions
DE69523438T2 (de
Inventor
Anand R Baichwal
Troy W Mccall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penwest Pharmaceuticals Co
Original Assignee
Mendell Edward Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mendell Edward Co Inc filed Critical Mendell Edward Co Inc
Application granted granted Critical
Publication of DE69523438D1 publication Critical patent/DE69523438D1/de
Publication of DE69523438T2 publication Critical patent/DE69523438T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE69523438T 1994-04-25 1995-04-06 Orale metoprolol-dosisform des typs "einmal täglich" Expired - Fee Related DE69523438T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/232,719 US5399362A (en) 1994-04-25 1994-04-25 Once-a-day metoprolol oral dosage form
PCT/US1995/004118 WO1995028917A1 (en) 1994-04-25 1995-04-06 Once-a-day metoprolol oral dosage form

Publications (2)

Publication Number Publication Date
DE69523438D1 true DE69523438D1 (de) 2001-11-29
DE69523438T2 DE69523438T2 (de) 2002-05-16

Family

ID=22874261

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69533492T Expired - Fee Related DE69533492T2 (de) 1994-04-25 1995-04-06 Orale Metoprolol-Dosisform des Typs "einmal täglich"
DE69523438T Expired - Fee Related DE69523438T2 (de) 1994-04-25 1995-04-06 Orale metoprolol-dosisform des typs "einmal täglich"

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69533492T Expired - Fee Related DE69533492T2 (de) 1994-04-25 1995-04-06 Orale Metoprolol-Dosisform des Typs "einmal täglich"

Country Status (16)

Country Link
US (1) US5399362A (de)
EP (3) EP1110542B1 (de)
JP (1) JPH08512062A (de)
KR (1) KR0184339B1 (de)
CN (1) CN1131028C (de)
AT (2) ATE275395T1 (de)
AU (1) AU684944B2 (de)
CA (1) CA2164619C (de)
DE (2) DE69533492T2 (de)
DK (2) DK1110542T3 (de)
ES (2) ES2161882T3 (de)
FI (1) FI118001B (de)
HU (1) HU226375B1 (de)
IL (1) IL113325A (de)
PT (2) PT723435E (de)
WO (1) WO1995028917A1 (de)

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CA2452871C (en) 2001-07-06 2011-10-04 Endo Pharmaceuticals, Inc. Oxymorphone controlled release formulations
US8329216B2 (en) * 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
JP2005022975A (ja) * 2001-08-09 2005-01-27 Wakunaga Pharmaceut Co Ltd 徐放性医薬組成物
US20030091635A1 (en) * 2001-09-26 2003-05-15 Baichwal Anand R. Opioid formulations having reduced potential for abuse
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AU2003230805A1 (en) * 2002-04-05 2003-10-27 Penwest Pharmaceuticals Co. Sustained release metoprolol formulations
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US7314640B2 (en) * 2003-07-11 2008-01-01 Mongkol Sriwongjanya Formulation and process for drug loaded cores
AU2004273958A1 (en) * 2003-09-19 2005-03-31 Penwest Pharmaceuticals Co. Chronotherapeutic dosage forms
AP2006003585A0 (en) * 2003-09-19 2006-04-30 Penwest Pharmaceuticals Co Delayed release dosage forms.
WO2005077331A1 (en) * 2004-02-11 2005-08-25 Athpharma Limited Chronotherapeutic compositions and methods of their use
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US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
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US20090124650A1 (en) * 2007-06-21 2009-05-14 Endo Pharmaceuticals, Inc. Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instructions on Effects of Alcohol
US20100160274A1 (en) * 2007-09-07 2010-06-24 Sharon Sageman 7-KETO DHEA for Psychiatric Use
US20110207718A1 (en) 2008-08-06 2011-08-25 Gosforth Centre (Holdings) Pty Ltd. Compositions and methods for treating psychiatric disorders
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US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
CN101716157B (zh) * 2008-10-09 2013-02-27 北京德众万全药物技术开发有限公司 一种美托洛尔口服药物组合物及其制备方法
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
WO2011023392A1 (en) 2009-08-28 2011-03-03 Grünenthal GmbH Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol or 6-dimethylaminomethyl-1-(3-hydroxy-phenyl)-cyclohexane-1,3-diol and an antiepileptic
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
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GB201111712D0 (en) 2011-07-08 2011-08-24 Gosforth Ct Holdings Pty Ltd Pharmaceutical compositions
CN102552196B (zh) * 2011-12-20 2013-08-14 中国药科大学 利用喷雾干燥法制备琥珀酸美托洛尔缓释微囊的方法
US9320725B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
US9308196B2 (en) 2012-05-18 2016-04-12 Gruenenthal Gmbh Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
US9345689B2 (en) 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US8912226B2 (en) 2012-05-18 2014-12-16 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSAR
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9320729B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US20150133516A1 (en) 2013-11-13 2015-05-14 Brian K. Adams Methods and Compositions for Treating ADHD
WO2017004526A1 (en) 2015-07-02 2017-01-05 University Of Louisville Research Foundation, Inc. EDIBLE PLANT-DERIVED MICROVESICLE COMPOSITIONS FOR DELIVERY OF miRNA AND METHODS FOR TREATMENT OF CANCER

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Also Published As

Publication number Publication date
WO1995028917A1 (en) 1995-11-02
EP0723435A4 (de) 1996-11-06
EP1110542A3 (de) 2001-09-19
ES2161882T3 (es) 2001-12-16
EP0723435B1 (de) 2001-10-24
ATE275395T1 (de) 2004-09-15
FI956210A (fi) 1995-12-22
ES2223669T3 (es) 2005-03-01
FI118001B (fi) 2007-05-31
EP1470816A3 (de) 2005-03-02
EP1470816A2 (de) 2004-10-27
MX9600024A (es) 1998-11-30
IL113325A (en) 1999-03-12
DK1110542T3 (da) 2005-01-10
US5399362A (en) 1995-03-21
HU9503457D0 (en) 1996-02-28
FI956210A0 (fi) 1995-12-22
DE69523438T2 (de) 2002-05-16
DK0723435T3 (da) 2002-02-11
HUT75103A (en) 1997-04-28
CN1131028C (zh) 2003-12-17
CA2164619A1 (en) 1995-11-02
DE69533492D1 (de) 2004-10-14
DE69533492T2 (de) 2005-01-27
HU226375B1 (en) 2008-10-28
AU684944B2 (en) 1998-01-08
EP1110542B1 (de) 2004-09-08
KR0184339B1 (ko) 1999-05-01
EP1110542A2 (de) 2001-06-27
EP0723435A1 (de) 1996-07-31
PT1110542E (pt) 2005-01-31
ATE207345T1 (de) 2001-11-15
CN1127470A (zh) 1996-07-24
PT723435E (pt) 2002-02-28
AU2355695A (en) 1995-11-16
IL113325A0 (en) 1995-07-31
CA2164619C (en) 2000-06-20
JPH08512062A (ja) 1996-12-17

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: PENWEST PHARMACEUTICALS CO., PATTERSON, N.Y., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee