DE69533492D1 - Orale Metoprolol-Dosisform des Typs "einmal täglich" - Google Patents

Orale Metoprolol-Dosisform des Typs "einmal täglich"

Info

Publication number
DE69533492D1
DE69533492D1 DE69533492T DE69533492T DE69533492D1 DE 69533492 D1 DE69533492 D1 DE 69533492D1 DE 69533492 T DE69533492 T DE 69533492T DE 69533492 T DE69533492 T DE 69533492T DE 69533492 D1 DE69533492 D1 DE 69533492D1
Authority
DE
Germany
Prior art keywords
metoprolol
dosage form
oral
day
once
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69533492T
Other languages
English (en)
Other versions
DE69533492T2 (de
Inventor
Anand R Baichwal
Troy W Mccall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penwest Pharmaceuticals Co
Original Assignee
Penwest Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penwest Pharmaceuticals Co filed Critical Penwest Pharmaceuticals Co
Application granted granted Critical
Publication of DE69533492D1 publication Critical patent/DE69533492D1/de
Publication of DE69533492T2 publication Critical patent/DE69533492T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE69533492T 1994-04-25 1995-04-06 Orale Metoprolol-Dosisform des Typs "einmal täglich" Expired - Fee Related DE69533492T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US232719 1994-04-25
US08/232,719 US5399362A (en) 1994-04-25 1994-04-25 Once-a-day metoprolol oral dosage form

Publications (2)

Publication Number Publication Date
DE69533492D1 true DE69533492D1 (de) 2004-10-14
DE69533492T2 DE69533492T2 (de) 2005-01-27

Family

ID=22874261

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69533492T Expired - Fee Related DE69533492T2 (de) 1994-04-25 1995-04-06 Orale Metoprolol-Dosisform des Typs "einmal täglich"
DE69523438T Expired - Fee Related DE69523438T2 (de) 1994-04-25 1995-04-06 Orale metoprolol-dosisform des typs "einmal täglich"

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69523438T Expired - Fee Related DE69523438T2 (de) 1994-04-25 1995-04-06 Orale metoprolol-dosisform des typs "einmal täglich"

Country Status (16)

Country Link
US (1) US5399362A (de)
EP (3) EP1110542B1 (de)
JP (1) JPH08512062A (de)
KR (1) KR0184339B1 (de)
CN (1) CN1131028C (de)
AT (2) ATE275395T1 (de)
AU (1) AU684944B2 (de)
CA (1) CA2164619C (de)
DE (2) DE69533492T2 (de)
DK (2) DK0723435T3 (de)
ES (2) ES2161882T3 (de)
FI (1) FI118001B (de)
HU (1) HU226375B1 (de)
IL (1) IL113325A (de)
PT (2) PT723435E (de)
WO (1) WO1995028917A1 (de)

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EP1135106B1 (de) * 1999-09-30 2008-04-09 Penwest Pharmaceuticals Co. Matrixsystem mit verzögerter freisetzung für hochlösliche wirkstoffe
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CN1268338C (zh) * 2001-07-06 2006-08-09 恩德制药公司 用作止痛剂的6－羟基羟吗啡酮的口服给药
US8329216B2 (en) * 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
JP2005022975A (ja) * 2001-08-09 2005-01-27 Wakunaga Pharmaceut Co Ltd 徐放性医薬組成物
CA2459976A1 (en) * 2001-09-26 2003-04-03 Penwest Pharmaceuticals Company Opioid formulations having reduced potential for abuse
US6635675B2 (en) 2001-11-05 2003-10-21 Cypress Bioscience, Inc. Method of treating chronic fatigue syndrome
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EP1499295A4 (de) * 2002-04-05 2006-04-05 Penwest Pharmaceuticals Co Metoprolol-formulierungen mit verzögerter freisetzung
US6936574B2 (en) * 2002-08-30 2005-08-30 Halliburton Energy Services, Inc. Process for controlling gas migration during well cementing
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US7314640B2 (en) * 2003-07-11 2008-01-01 Mongkol Sriwongjanya Formulation and process for drug loaded cores
WO2005027843A2 (en) * 2003-09-19 2005-03-31 Penwest Pharmaceuticals Co. Chronotherapeutic dosage forms
US8389008B2 (en) * 2003-09-19 2013-03-05 Penwest Pharmaceuticals Co. Delayed release dosage forms
JP2007522203A (ja) * 2004-02-11 2007-08-09 アスファーマ・リミテッド 時間療法用組成物とそれらの使用方法
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US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
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US20090124650A1 (en) * 2007-06-21 2009-05-14 Endo Pharmaceuticals, Inc. Method of Treating Pain Utilizing Controlled Release Oxymorphone Pharmaceutical Compositions and Instructions on Effects of Alcohol
US20100160274A1 (en) * 2007-09-07 2010-06-24 Sharon Sageman 7-KETO DHEA for Psychiatric Use
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US20100190752A1 (en) * 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
CN101716157B (zh) * 2008-10-09 2013-02-27 北京德众万全药物技术开发有限公司 一种美托洛尔口服药物组合物及其制备方法
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
AR077987A1 (es) 2009-08-28 2011-10-05 Gruenenthal Gmbh Combinacion farmaceutica que comprende 6-dimetilaminometil-1-(3-metoxifenil)-ciclohexano-1,3-diol o 6-dimetilaminometil-1-(3-hidroxifenil)-ciclohexano-1,3-diol y un antiepileptico
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
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GB201111712D0 (en) 2011-07-08 2011-08-24 Gosforth Ct Holdings Pty Ltd Pharmaceutical compositions
CN102552196B (zh) * 2011-12-20 2013-08-14 中国药科大学 利用喷雾干燥法制备琥珀酸美托洛尔缓释微囊的方法
US8912226B2 (en) 2012-05-18 2014-12-16 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSAR
US9320729B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US9308196B2 (en) 2012-05-18 2016-04-12 Gruenenthal Gmbh Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
US9320725B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
US9345689B2 (en) 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
WO2015073736A1 (en) 2013-11-13 2015-05-21 Arbor Pharmaceuticals, Llc Methods and compositions for treating adhd
WO2017004526A1 (en) 2015-07-02 2017-01-05 University Of Louisville Research Foundation, Inc. EDIBLE PLANT-DERIVED MICROVESICLE COMPOSITIONS FOR DELIVERY OF miRNA AND METHODS FOR TREATMENT OF CANCER

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Also Published As

Publication number Publication date
IL113325A (en) 1999-03-12
CA2164619C (en) 2000-06-20
DE69533492T2 (de) 2005-01-27
EP1110542A2 (de) 2001-06-27
EP0723435B1 (de) 2001-10-24
FI118001B (fi) 2007-05-31
EP0723435A1 (de) 1996-07-31
DE69523438D1 (de) 2001-11-29
DK0723435T3 (da) 2002-02-11
FI956210A0 (fi) 1995-12-22
MX9600024A (es) 1998-11-30
US5399362A (en) 1995-03-21
EP1110542B1 (de) 2004-09-08
EP1470816A3 (de) 2005-03-02
EP0723435A4 (de) 1996-11-06
ATE275395T1 (de) 2004-09-15
ATE207345T1 (de) 2001-11-15
AU684944B2 (en) 1998-01-08
IL113325A0 (en) 1995-07-31
WO1995028917A1 (en) 1995-11-02
CN1127470A (zh) 1996-07-24
CA2164619A1 (en) 1995-11-02
DE69523438T2 (de) 2002-05-16
HUT75103A (en) 1997-04-28
EP1110542A3 (de) 2001-09-19
KR0184339B1 (ko) 1999-05-01
ES2161882T3 (es) 2001-12-16
EP1470816A2 (de) 2004-10-27
HU226375B1 (en) 2008-10-28
ES2223669T3 (es) 2005-03-01
FI956210A (fi) 1995-12-22
DK1110542T3 (da) 2005-01-10
CN1131028C (zh) 2003-12-17
PT723435E (pt) 2002-02-28
PT1110542E (pt) 2005-01-31
JPH08512062A (ja) 1996-12-17
HU9503457D0 (en) 1996-02-28
AU2355695A (en) 1995-11-16

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee