MX9304403A - Derivados farmacologicamente activos de ó-(aminometilo terciario)-bencenmetanol - Google Patents

Derivados farmacologicamente activos de ó-(aminometilo terciario)-bencenmetanol

Info

Publication number
MX9304403A
MX9304403A MX9304403A MX9304403A MX9304403A MX 9304403 A MX9304403 A MX 9304403A MX 9304403 A MX9304403 A MX 9304403A MX 9304403 A MX9304403 A MX 9304403A MX 9304403 A MX9304403 A MX 9304403A
Authority
MX
Mexico
Prior art keywords
pct
bencenmetanol
pharmacologically active
active derivatives
tertiary aminomethyl
Prior art date
Application number
MX9304403A
Other languages
English (en)
Inventor
Nils-Erik Willman
Lennart Gustav Nordh
Gustav Lennart Persson
Bengt Christer Hans Sjoegren
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of MX9304403A publication Critical patent/MX9304403A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/70—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Abstract

Nuevos compuestos de la fórmula general I: En donde: R1 se selecciona a partir de alquilo, alcoxi, alqueniloxi, arilalcoxi, alquiltio y alqueniltio; R2 se selecciona a partir de halógeno, hidroxi, alquilo, alcoxi, alqueniloxi, alquiltio, alqueniltio, alquilamino, trifluorometilo, ciano, nitro, alquilsulfinilo, alquilsulfonilo y alquilo; R3, R4 cualquiera de los dos independientemente representan alquilo o alquenilo, o R3 y R4 están interconectados para formar un sistema heterocíclico con el átomo de nitrógeno, y contienen opcionalmente uno o más heteroátomos y sales fisiológicamente aceptables, de los mismos, su uso como substancias terapéuticas, especialmente como agentes controladores del aparato urinario, su uso para preparar un medicamento controlador del aparato urinario, compuestos farmacéuticos que los contienen, y métodos para preparar los nuevos compuestos.
MX9304403A 1992-07-22 1993-07-21 Derivados farmacologicamente activos de ó-(aminometilo terciario)-bencenmetanol MX9304403A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9202218A SE9202218D0 (sv) 1992-07-22 1992-07-22 Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation

Publications (1)

Publication Number Publication Date
MX9304403A true MX9304403A (es) 1994-04-29

Family

ID=20386825

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304403A MX9304403A (es) 1992-07-22 1993-07-21 Derivados farmacologicamente activos de ó-(aminometilo terciario)-bencenmetanol

Country Status (22)

Country Link
US (1) US5527821A (es)
EP (1) EP0651735B1 (es)
JP (1) JPH07509699A (es)
KR (1) KR950702522A (es)
CN (1) CN1085543A (es)
AT (1) ATE166339T1 (es)
AU (1) AU672989B2 (es)
BR (1) BR9306870A (es)
CA (1) CA2140781C (es)
CZ (1) CZ13395A3 (es)
DE (1) DE69318715D1 (es)
FI (1) FI950209A0 (es)
HU (1) HUT72632A (es)
MX (1) MX9304403A (es)
NO (1) NO301760B1 (es)
NZ (1) NZ254309A (es)
RU (1) RU2111205C1 (es)
SE (1) SE9202218D0 (es)
SK (1) SK7695A3 (es)
TW (1) TW261605B (es)
WO (1) WO1994002442A1 (es)
ZA (1) ZA935045B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
AU6747698A (en) * 1997-04-11 1998-11-11 Nippon Shinyaku Co. Ltd. Remedies for frequent urination and urinary incontinence
US6008412A (en) * 1997-10-14 1999-12-28 Eli Lilly And Company Process to make chiral compounds
US6323231B1 (en) 2000-02-17 2001-11-27 Abbott Laboratories Use of α1A adrenoceptor agonists with α1B and α1D antagonism for the treatment of stress urinary incontinence
US6503190B1 (en) 2000-09-29 2003-01-07 Ethicon Endo-Surgery, Inc. Vaginal pessary
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE210031C (es) *
US4349549A (en) * 1981-05-18 1982-09-14 Syntex (U.S.A.) Inc. Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s
PL140232B1 (en) * 1982-07-05 1987-04-30 Warszawskie Zaklady Farma Method of obtaining derivatives of 1-aryl-2-aminoestanole
EP0103830A3 (de) * 1982-09-22 1985-07-31 Bayer Ag Wachstumsfördernde Phenylethylamin-Derivate
EP0213108A3 (de) * 1985-06-26 1987-07-15 Kurt Dr. Burghart Pharmazeutische Zubereitung mit einem Antihypotonikum als wirksames Mittel
CA2061665C (en) * 1991-02-25 2002-04-16 Mark Mortensen Foreman Treatment of lower urinary tract disorders

Also Published As

Publication number Publication date
NO301760B1 (no) 1997-12-08
CZ13395A3 (en) 1995-11-15
AU4595093A (en) 1994-02-14
CA2140781A1 (en) 1994-02-03
HU9500175D0 (en) 1995-03-28
SK7695A3 (en) 1995-07-11
BR9306870A (pt) 1998-12-08
RU95104934A (ru) 1997-04-10
SE9202218D0 (sv) 1992-07-22
ZA935045B (en) 1994-02-07
FI950209A (fi) 1995-01-18
NO950177D0 (no) 1995-01-17
ATE166339T1 (de) 1998-06-15
AU672989B2 (en) 1996-10-24
CA2140781C (en) 1998-09-29
NZ254309A (en) 1996-08-27
RU2111205C1 (ru) 1998-05-20
EP0651735A1 (en) 1995-05-10
WO1994002442A1 (en) 1994-02-03
US5527821A (en) 1996-06-18
DE69318715D1 (de) 1998-06-25
TW261605B (es) 1995-11-01
KR950702522A (ko) 1995-07-29
CN1085543A (zh) 1994-04-20
FI950209A0 (fi) 1995-01-18
NO950177L (no) 1995-01-17
JPH07509699A (ja) 1995-10-26
EP0651735B1 (en) 1998-05-20
HUT72632A (en) 1996-05-28

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees