DE69318715D1 - Pharmakologisch aktive alpha-(tertiär-aminoethyl)-phenylmethanol-derivate - Google Patents

Pharmakologisch aktive alpha-(tertiär-aminoethyl)-phenylmethanol-derivate

Info

Publication number
DE69318715D1
DE69318715D1 DE69318715T DE69318715T DE69318715D1 DE 69318715 D1 DE69318715 D1 DE 69318715D1 DE 69318715 T DE69318715 T DE 69318715T DE 69318715 T DE69318715 T DE 69318715T DE 69318715 D1 DE69318715 D1 DE 69318715D1
Authority
DE
Germany
Prior art keywords
aminoethyl
tertiary
pct
pharmacologically active
active alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69318715T
Other languages
English (en)
Inventor
Nils-Erik Willman
Bengt Sjoegren
Lennart Nordh
Gustav Persson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia and Upjohn AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn AB filed Critical Pharmacia and Upjohn AB
Application granted granted Critical
Publication of DE69318715D1 publication Critical patent/DE69318715D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/70—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
DE69318715T 1992-07-22 1993-07-20 Pharmakologisch aktive alpha-(tertiär-aminoethyl)-phenylmethanol-derivate Expired - Lifetime DE69318715D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9202218A SE9202218D0 (sv) 1992-07-22 1992-07-22 Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation
PCT/SE1993/000635 WO1994002442A1 (en) 1992-07-22 1993-07-20 PHARMACOLOGICALLY ACTIVE α-[TERTIARY-AMINOMETHYL]-BENZENEMETHANOL DERIVATIVES

Publications (1)

Publication Number Publication Date
DE69318715D1 true DE69318715D1 (de) 1998-06-25

Family

ID=20386825

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69318715T Expired - Lifetime DE69318715D1 (de) 1992-07-22 1993-07-20 Pharmakologisch aktive alpha-(tertiär-aminoethyl)-phenylmethanol-derivate

Country Status (22)

Country Link
US (1) US5527821A (de)
EP (1) EP0651735B1 (de)
JP (1) JPH07509699A (de)
KR (1) KR950702522A (de)
CN (1) CN1085543A (de)
AT (1) ATE166339T1 (de)
AU (1) AU672989B2 (de)
BR (1) BR9306870A (de)
CA (1) CA2140781C (de)
CZ (1) CZ13395A3 (de)
DE (1) DE69318715D1 (de)
FI (1) FI950209A (de)
HU (1) HUT72632A (de)
MX (1) MX9304403A (de)
NO (1) NO301760B1 (de)
NZ (1) NZ254309A (de)
RU (1) RU2111205C1 (de)
SE (1) SE9202218D0 (de)
SK (1) SK7695A3 (de)
TW (1) TW261605B (de)
WO (1) WO1994002442A1 (de)
ZA (1) ZA935045B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
JP4085433B2 (ja) * 1997-04-11 2008-05-14 日本新薬株式会社 頻尿・尿失禁治療剤
US6008412A (en) * 1997-10-14 1999-12-28 Eli Lilly And Company Process to make chiral compounds
US6323231B1 (en) 2000-02-17 2001-11-27 Abbott Laboratories Use of α1A adrenoceptor agonists with α1B and α1D antagonism for the treatment of stress urinary incontinence
US6503190B1 (en) 2000-09-29 2003-01-07 Ethicon Endo-Surgery, Inc. Vaginal pessary
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE210031C (de) *
US4349549A (en) * 1981-05-18 1982-09-14 Syntex (U.S.A.) Inc. Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s
PL140232B1 (en) * 1982-07-05 1987-04-30 Warszawskie Zaklady Farma Method of obtaining derivatives of 1-aryl-2-aminoestanole
EP0103830A3 (de) * 1982-09-22 1985-07-31 Bayer Ag Wachstumsfördernde Phenylethylamin-Derivate
EP0213108A3 (de) * 1985-06-26 1987-07-15 Kurt Dr. Burghart Pharmazeutische Zubereitung mit einem Antihypotonikum als wirksames Mittel
CA2061665C (en) * 1991-02-25 2002-04-16 Mark Mortensen Foreman Treatment of lower urinary tract disorders

Also Published As

Publication number Publication date
KR950702522A (ko) 1995-07-29
FI950209A0 (fi) 1995-01-18
SE9202218D0 (sv) 1992-07-22
BR9306870A (pt) 1998-12-08
EP0651735B1 (de) 1998-05-20
EP0651735A1 (de) 1995-05-10
RU95104934A (ru) 1997-04-10
AU4595093A (en) 1994-02-14
JPH07509699A (ja) 1995-10-26
MX9304403A (es) 1994-04-29
NZ254309A (en) 1996-08-27
SK7695A3 (en) 1995-07-11
CA2140781C (en) 1998-09-29
TW261605B (de) 1995-11-01
WO1994002442A1 (en) 1994-02-03
CA2140781A1 (en) 1994-02-03
NO950177L (no) 1995-01-17
AU672989B2 (en) 1996-10-24
CZ13395A3 (en) 1995-11-15
ZA935045B (en) 1994-02-07
RU2111205C1 (ru) 1998-05-20
US5527821A (en) 1996-06-18
FI950209A (fi) 1995-01-18
ATE166339T1 (de) 1998-06-15
NO950177D0 (no) 1995-01-17
HU9500175D0 (en) 1995-03-28
HUT72632A (en) 1996-05-28
NO301760B1 (no) 1997-12-08
CN1085543A (zh) 1994-04-20

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Legal Events

Date Code Title Description
8332 No legal effect for de