ES2161882T3 - Forma de dosificacion oral de metoprolol, de una vez al dia. - Google Patents

Forma de dosificacion oral de metoprolol, de una vez al dia.

Info

Publication number
ES2161882T3
ES2161882T3 ES95917552T ES95917552T ES2161882T3 ES 2161882 T3 ES2161882 T3 ES 2161882T3 ES 95917552 T ES95917552 T ES 95917552T ES 95917552 T ES95917552 T ES 95917552T ES 2161882 T3 ES2161882 T3 ES 2161882T3
Authority
ES
Spain
Prior art keywords
dosage form
metoprolol
day
once
oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95917552T
Other languages
English (en)
Inventor
Anand R Baichwal
Troy W Mccall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mendell Edward Co Inc
Original Assignee
Mendell Edward Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mendell Edward Co Inc filed Critical Mendell Edward Co Inc
Application granted granted Critical
Publication of ES2161882T3 publication Critical patent/ES2161882T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE PRESENTA UNA DOSIS SOLIDA ORAL DE LIBERACION SOSTENIDA DE UNA FORMULACION FARMACEUTICA DE METOPROLOL QUE INCLUYE UN EXCIPIENTE DE LIBERACION SOSTENIDA QUE INCLUYE UN AGENTE GELIFICANTE, UN DILUYENTE FARMACEUTICO INERTE, UN AGENTE DE RETICULACION CATIONICO. LA FORMULACION PROPORCIONA UNA LIBERACION DE METOPROLOL DURANTE AL MENOS 24 HORAS. METODOS DE PREPARACION Y METODOS DE TRATAMIENTO QUE UTILIZAN LAS PREPARACIONES DE LA INVENCION.
ES95917552T 1994-04-25 1995-04-06 Forma de dosificacion oral de metoprolol, de una vez al dia. Expired - Lifetime ES2161882T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/232,719 US5399362A (en) 1994-04-25 1994-04-25 Once-a-day metoprolol oral dosage form

Publications (1)

Publication Number Publication Date
ES2161882T3 true ES2161882T3 (es) 2001-12-16

Family

ID=22874261

Family Applications (2)

Application Number Title Priority Date Filing Date
ES95917552T Expired - Lifetime ES2161882T3 (es) 1994-04-25 1995-04-06 Forma de dosificacion oral de metoprolol, de una vez al dia.
ES01107023T Expired - Lifetime ES2223669T3 (es) 1994-04-25 1995-04-06 Forma oral de dosificacion "una vez al dia" de metoprolol.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES01107023T Expired - Lifetime ES2223669T3 (es) 1994-04-25 1995-04-06 Forma oral de dosificacion "una vez al dia" de metoprolol.

Country Status (16)

Country Link
US (1) US5399362A (es)
EP (3) EP1110542B1 (es)
JP (1) JPH08512062A (es)
KR (1) KR0184339B1 (es)
CN (1) CN1131028C (es)
AT (2) ATE275395T1 (es)
AU (1) AU684944B2 (es)
CA (1) CA2164619C (es)
DE (2) DE69533492T2 (es)
DK (2) DK1110542T3 (es)
ES (2) ES2161882T3 (es)
FI (1) FI118001B (es)
HU (1) HU226375B1 (es)
IL (1) IL113325A (es)
PT (2) PT723435E (es)
WO (1) WO1995028917A1 (es)

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CA2452871C (en) 2001-07-06 2011-10-04 Endo Pharmaceuticals, Inc. Oxymorphone controlled release formulations
US8329216B2 (en) * 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
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US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
CN101716157B (zh) * 2008-10-09 2013-02-27 北京德众万全药物技术开发有限公司 一种美托洛尔口服药物组合物及其制备方法
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations
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US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
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US9345689B2 (en) 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US8912226B2 (en) 2012-05-18 2014-12-16 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSAR
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9320729B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
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Also Published As

Publication number Publication date
WO1995028917A1 (en) 1995-11-02
EP0723435A4 (en) 1996-11-06
EP1110542A3 (en) 2001-09-19
EP0723435B1 (en) 2001-10-24
ATE275395T1 (de) 2004-09-15
FI956210A (fi) 1995-12-22
ES2223669T3 (es) 2005-03-01
FI118001B (fi) 2007-05-31
EP1470816A3 (en) 2005-03-02
EP1470816A2 (en) 2004-10-27
MX9600024A (es) 1998-11-30
IL113325A (en) 1999-03-12
DK1110542T3 (da) 2005-01-10
US5399362A (en) 1995-03-21
HU9503457D0 (en) 1996-02-28
FI956210A0 (fi) 1995-12-22
DE69523438T2 (de) 2002-05-16
DE69523438D1 (de) 2001-11-29
DK0723435T3 (da) 2002-02-11
HUT75103A (en) 1997-04-28
CN1131028C (zh) 2003-12-17
CA2164619A1 (en) 1995-11-02
DE69533492D1 (de) 2004-10-14
DE69533492T2 (de) 2005-01-27
HU226375B1 (en) 2008-10-28
AU684944B2 (en) 1998-01-08
EP1110542B1 (en) 2004-09-08
KR0184339B1 (ko) 1999-05-01
EP1110542A2 (en) 2001-06-27
EP0723435A1 (en) 1996-07-31
PT1110542E (pt) 2005-01-31
ATE207345T1 (de) 2001-11-15
CN1127470A (zh) 1996-07-24
PT723435E (pt) 2002-02-28
AU2355695A (en) 1995-11-16
IL113325A0 (en) 1995-07-31
CA2164619C (en) 2000-06-20
JPH08512062A (ja) 1996-12-17

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