SI1685829T1 - Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine - Google Patents

Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine

Info

Publication number
SI1685829T1
SI1685829T1 SI200331224T SI200331224T SI1685829T1 SI 1685829 T1 SI1685829 T1 SI 1685829T1 SI 200331224 T SI200331224 T SI 200331224T SI 200331224 T SI200331224 T SI 200331224T SI 1685829 T1 SI1685829 T1 SI 1685829T1
Authority
SI
Slovenia
Prior art keywords
alkyl
hydrogen
optionally substituted
phenyl
och
Prior art date
Application number
SI200331224T
Other languages
English (en)
Inventor
Klaus Dr Schiene
Gunter Haase
Babette-Yvonne Dr Kogel
Elmar Dr Friderichs
Urich Dr Jahnel
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32395002&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1685829(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10254785A external-priority patent/DE10254785A1/de
Priority claimed from DE2003126103 external-priority patent/DE10326103A1/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of SI1685829T1 publication Critical patent/SI1685829T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI200331224T 2002-11-22 2003-11-18 Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine SI1685829T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10254785A DE10254785A1 (de) 2002-11-22 2002-11-22 Kombination ausgewählter Analgetika mit COX II-Inhibitoren
DE2003126103 DE10326103A1 (de) 2003-06-06 2003-06-06 Kombination ausgewählter Analgetika mit COX II-Inhibitoren
EP05027145A EP1685829B1 (de) 2002-11-22 2003-11-18 Verwendung von (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexan-1,3-diol zur Behandlung von Entzündungsschmerz

Publications (1)

Publication Number Publication Date
SI1685829T1 true SI1685829T1 (sl) 2008-08-31

Family

ID=32395002

Family Applications (4)

Application Number Title Priority Date Filing Date
SI200331224T SI1685829T1 (sl) 2002-11-22 2003-11-18 Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine
SI200332616T SI3241550T1 (sl) 2002-11-22 2003-11-18 Uporaba (1R, 2R) -3- (3-dimetilimanino-1-etil-2-metil-propil)-fenola za zdravljenje vnetnih bolečin
SI200331816T SI1839654T1 (sl) 2002-11-22 2003-11-18 Uporaba (1R, 2R)-3-(3-dimetilamino-1-etil-2-metil- propil)-fenola za zdravljenje vnetne bolečine
SI200332541T SI1562567T1 (sl) 2002-11-22 2003-11-18 Kombinacija izbranih analgetikov s COX II-zaviralci

Family Applications After (3)

Application Number Title Priority Date Filing Date
SI200332616T SI3241550T1 (sl) 2002-11-22 2003-11-18 Uporaba (1R, 2R) -3- (3-dimetilimanino-1-etil-2-metil-propil)-fenola za zdravljenje vnetnih bolečin
SI200331816T SI1839654T1 (sl) 2002-11-22 2003-11-18 Uporaba (1R, 2R)-3-(3-dimetilamino-1-etil-2-metil- propil)-fenola za zdravljenje vnetne bolečine
SI200332541T SI1562567T1 (sl) 2002-11-22 2003-11-18 Kombinacija izbranih analgetikov s COX II-zaviralci

Country Status (13)

Country Link
US (7) US7786160B2 (sl)
EP (6) EP1839654B9 (sl)
AT (2) ATE391498T1 (sl)
AU (1) AU2003283410A1 (sl)
CY (4) CY1108141T1 (sl)
DE (2) DE50309605D1 (sl)
DK (4) DK1839654T3 (sl)
ES (4) ES2640404T3 (sl)
HU (2) HUE051024T2 (sl)
LT (1) LT1562567T (sl)
PT (4) PT1839654E (sl)
SI (4) SI1685829T1 (sl)
WO (1) WO2004047823A1 (sl)

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LT1562567T (lt) 2002-11-22 2017-08-25 Grünenthal GmbH Pasirinktų analgetikų ir cox-ii slopiklių derinys
DE10356362A1 (de) 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen
US20070254960A1 (en) * 2006-04-28 2007-11-01 Gruenenthal Gmbh Pharmaceutical combination
EP2012764B1 (en) 2006-04-28 2011-01-12 Grünenthal GmbH Pharmaceutical combination comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol
ES2358763T3 (es) * 2006-04-28 2011-05-13 Grünenthal GmbH Combinación farmacéutica que comprende 3-(3-dimetilamino-1-etil-2-metilpropil)fenol y un nsaid.
DE102007012165A1 (de) * 2007-03-12 2008-09-18 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
DE102007022790A1 (de) * 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose
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EP2085081A1 (de) 2008-02-04 2009-08-05 Grünenthal GmbH 3-(2-Dimethylaminomethyl-cyclohexyl)-phenol gegen polyneuropathischen Schmerz
EP2331087A1 (en) * 2008-09-05 2011-06-15 Grünenthal GmbH Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3 diol and paracetamol
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
RU2011112445A (ru) * 2008-09-05 2012-10-10 Грюненталь ГмбХ (DE) Фармацевтическая комбинация, которая содержит 6-диметиламинометил-1-(3-метоксифенил)-циклогексан-1,3-диол и нпвс
JP6216489B2 (ja) * 2008-10-30 2017-10-18 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 新規の、効力のあるタペンタドール剤形
KR20120015332A (ko) * 2009-04-30 2012-02-21 그뤼넨탈 게엠베하 류마티스성 통증을 치료하기 위한 １?페닐?３?디메틸아미노프로판 화합물의 용도
WO2011023392A1 (en) * 2009-08-28 2011-03-03 Grünenthal GmbH Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol or 6-dimethylaminomethyl-1-(3-hydroxy-phenyl)-cyclohexane-1,3-diol and an antiepileptic
CN104276960B (zh) * 2014-09-26 2016-09-28 安徽省逸欣铭医药科技有限公司 盐酸他喷他多和塞来昔布共晶及其组合物和制备方法

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Also Published As

Publication number Publication date
US20100280126A1 (en) 2010-11-04
CY1119082T1 (el) 2018-01-10
HUE051024T2 (hu) 2021-03-01
DK1562567T3 (en) 2017-07-17
ES2304659T3 (es) 2008-10-16
US20100280129A1 (en) 2010-11-04
US20160279150A1 (en) 2016-09-29
PT1839654E (pt) 2010-07-06
EP1839654B9 (de) 2012-01-11
AU2003283410A1 (en) 2004-06-18
DK1839654T3 (da) 2010-08-16
US8618177B2 (en) 2013-12-31
EP1685829B1 (de) 2008-04-09
SI3241550T1 (sl) 2020-11-30
SI1562567T1 (sl) 2017-09-29
EP1562567A1 (de) 2005-08-17
EP1839654B1 (de) 2010-04-28
US20130109733A1 (en) 2013-05-02
LT1562567T (lt) 2017-08-25
EP3662904A1 (de) 2020-06-10
EP1839654A2 (de) 2007-10-03
CY1108141T1 (el) 2014-04-09
EP1908460A1 (de) 2008-04-09
PT1562567T (pt) 2017-08-24
DE50312678D1 (de) 2010-06-10
EP1562567B1 (de) 2017-06-14
PT1685829E (pt) 2008-05-15
CY1123286T1 (el) 2021-12-31
PT3241550T (pt) 2020-08-11
ATE465726T1 (de) 2010-05-15
EP1839654A3 (de) 2007-11-07
US8420691B2 (en) 2013-04-16
ES2345062T3 (es) 2010-09-14
US20050277687A1 (en) 2005-12-15
EP1685829A1 (de) 2006-08-02
WO2004047823A1 (de) 2004-06-10
US8003701B2 (en) 2011-08-23
EP3241550B1 (de) 2020-07-22
SI1839654T1 (sl) 2010-08-31
US10471079B2 (en) 2019-11-12
US8404749B2 (en) 2013-03-26
ES2819854T3 (es) 2021-04-19
US7786160B2 (en) 2010-08-31
HUE033042T2 (en) 2017-11-28
DE50309605D1 (de) 2008-05-21
ATE391498T1 (de) 2008-04-15
EP3241550A1 (de) 2017-11-08
DK3241550T3 (da) 2020-08-24
ES2640404T3 (es) 2017-11-02
US20070249724A1 (en) 2007-10-25
DK1685829T3 (da) 2008-07-21
US20100280017A1 (en) 2010-11-04
CY1110246T1 (el) 2015-01-14

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