DK3241550T3 - Anvendelse af (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol til behandling af inflammatoriske smerter - Google Patents

Anvendelse af (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol til behandling af inflammatoriske smerter Download PDF

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Publication number
DK3241550T3
DK3241550T3 DK17020237.8T DK17020237T DK3241550T3 DK 3241550 T3 DK3241550 T3 DK 3241550T3 DK 17020237 T DK17020237 T DK 17020237T DK 3241550 T3 DK3241550 T3 DK 3241550T3
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DK
Denmark
Prior art keywords
alkyl
hydrogen
optionally substituted
och
hydroxy
Prior art date
Application number
DK17020237.8T
Other languages
English (en)
Inventor
Klaus Schiene
Günter Haase
Babette-Yvonne Kögel
Elmar Friderichs
Ulrich Jahnel
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32395002&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3241550(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10254785A external-priority patent/DE10254785A1/de
Priority claimed from DE2003126103 external-priority patent/DE10326103A1/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Application granted granted Critical
Publication of DK3241550T3 publication Critical patent/DK3241550T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
DK17020237.8T 2002-11-22 2003-11-18 Anvendelse af (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol til behandling af inflammatoriske smerter DK3241550T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10254785A DE10254785A1 (de) 2002-11-22 2002-11-22 Kombination ausgewählter Analgetika mit COX II-Inhibitoren
DE2003126103 DE10326103A1 (de) 2003-06-06 2003-06-06 Kombination ausgewählter Analgetika mit COX II-Inhibitoren
EP03775368.8A EP1562567B1 (de) 2002-11-22 2003-11-18 Kombination ausgewählter analgetika mit cox ii-inhibitoren

Publications (1)

Publication Number Publication Date
DK3241550T3 true DK3241550T3 (da) 2020-08-24

Family

ID=32395002

Family Applications (4)

Application Number Title Priority Date Filing Date
DK07014417.5T DK1839654T3 (da) 2002-11-22 2003-11-18 Anvendelse af (1R, 2R)-3-(3-dimenthylamino-1-ethyl-2-methylpropyl)- phenol til behandling af betændelsessmerte
DK05027145T DK1685829T3 (da) 2002-11-22 2003-11-18 Anvendelse af (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexan-1,3-diol til behandling af betændelsessmerte
DK17020237.8T DK3241550T3 (da) 2002-11-22 2003-11-18 Anvendelse af (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol til behandling af inflammatoriske smerter
DK03775368.8T DK1562567T3 (da) 2002-11-22 2003-11-18 Kombination af udvalgte analgetika med COX II-hæmmere

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK07014417.5T DK1839654T3 (da) 2002-11-22 2003-11-18 Anvendelse af (1R, 2R)-3-(3-dimenthylamino-1-ethyl-2-methylpropyl)- phenol til behandling af betændelsessmerte
DK05027145T DK1685829T3 (da) 2002-11-22 2003-11-18 Anvendelse af (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexan-1,3-diol til behandling af betændelsessmerte

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03775368.8T DK1562567T3 (da) 2002-11-22 2003-11-18 Kombination af udvalgte analgetika med COX II-hæmmere

Country Status (13)

Country Link
US (7) US7786160B2 (da)
EP (6) EP1562567B1 (da)
AT (2) ATE465726T1 (da)
AU (1) AU2003283410A1 (da)
CY (4) CY1108141T1 (da)
DE (2) DE50312678D1 (da)
DK (4) DK1839654T3 (da)
ES (4) ES2819854T3 (da)
HU (2) HUE051024T2 (da)
LT (1) LT1562567T (da)
PT (4) PT3241550T (da)
SI (4) SI1839654T1 (da)
WO (1) WO2004047823A1 (da)

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PL2012764T3 (pl) * 2006-04-28 2011-04-29 Gruenenthal Gmbh Kombinacja farmaceutyczna zawierająca 3-(3-dimetyloamino-1-etylo-2-metylopropylo)fenol i Paracetamol
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DE102007022790A1 (de) * 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose
KR101972299B1 (ko) * 2007-11-23 2019-08-16 그뤼넨탈 게엠베하 타펜타돌 조성물
EP2085081A1 (de) 2008-02-04 2009-08-05 Grünenthal GmbH 3-(2-Dimethylaminomethyl-cyclohexyl)-phenol gegen polyneuropathischen Schmerz
US20100063009A1 (en) * 2008-09-05 2010-03-11 Gruenenthal Gmbh Pharmaceutical Combination Comprising 6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1.3-diol and an NSAID
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
CN102202660A (zh) * 2008-09-05 2011-09-28 格吕伦塔尔有限公司 包含6-二甲氨基甲基-1-(3-甲氧基-苯基)-环己烷-1,3-二醇和扑热息痛的药物组合
BRPI0921725A2 (pt) * 2008-10-30 2016-01-05 Grüenthal GmbH formas de dosagem potentes do tapentadol
SI2424514T1 (sl) * 2009-04-30 2017-05-31 Gruenenthal Gmbh Tapentadol za zdravljenje revmatoidne artritične bolečine
WO2011023392A1 (en) * 2009-08-28 2011-03-03 Grünenthal GmbH Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol or 6-dimethylaminomethyl-1-(3-hydroxy-phenyl)-cyclohexane-1,3-diol and an antiepileptic
CN104276960B (zh) * 2014-09-26 2016-09-28 安徽省逸欣铭医药科技有限公司 盐酸他喷他多和塞来昔布共晶及其组合物和制备方法

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Also Published As

Publication number Publication date
DE50312678D1 (de) 2010-06-10
EP3662904A1 (de) 2020-06-10
PT1685829E (pt) 2008-05-15
AU2003283410A1 (en) 2004-06-18
EP1839654A2 (de) 2007-10-03
US20070249724A1 (en) 2007-10-25
CY1110246T1 (el) 2015-01-14
ATE391498T1 (de) 2008-04-15
EP1562567A1 (de) 2005-08-17
EP3241550A1 (de) 2017-11-08
SI1685829T1 (sl) 2008-08-31
ATE465726T1 (de) 2010-05-15
HUE051024T2 (hu) 2021-03-01
US20100280129A1 (en) 2010-11-04
CY1119082T1 (el) 2018-01-10
LT1562567T (lt) 2017-08-25
US8003701B2 (en) 2011-08-23
US8420691B2 (en) 2013-04-16
US20100280017A1 (en) 2010-11-04
US8618177B2 (en) 2013-12-31
EP1685829A1 (de) 2006-08-02
DE50309605D1 (de) 2008-05-21
ES2304659T3 (es) 2008-10-16
EP1839654A3 (de) 2007-11-07
PT1562567T (pt) 2017-08-24
PT3241550T (pt) 2020-08-11
EP1839654B1 (de) 2010-04-28
DK1839654T3 (da) 2010-08-16
ES2345062T3 (es) 2010-09-14
US7786160B2 (en) 2010-08-31
US10471079B2 (en) 2019-11-12
US20050277687A1 (en) 2005-12-15
ES2819854T3 (es) 2021-04-19
DK1562567T3 (da) 2017-07-17
EP1562567B1 (de) 2017-06-14
SI1839654T1 (sl) 2010-08-31
US20130109733A1 (en) 2013-05-02
ES2640404T3 (es) 2017-11-02
PT1839654E (pt) 2010-07-06
US8404749B2 (en) 2013-03-26
HUE033042T2 (en) 2017-11-28
CY1108141T1 (el) 2014-04-09
EP1839654B9 (de) 2012-01-11
CY1123286T1 (el) 2021-12-31
EP1685829B1 (de) 2008-04-09
EP3241550B1 (de) 2020-07-22
US20160279150A1 (en) 2016-09-29
SI1562567T1 (sl) 2017-09-29
EP1908460A1 (de) 2008-04-09
SI3241550T1 (sl) 2020-11-30
WO2004047823A1 (de) 2004-06-10
DK1685829T3 (da) 2008-07-21
US20100280126A1 (en) 2010-11-04

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