CY1110246T1 - Χρησιμοποιηση (1r,2r)-3(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης για τη θεραπεια φλεγμονωδους πονου - Google Patents

Χρησιμοποιηση (1r,2r)-3(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης για τη θεραπεια φλεγμονωδους πονου

Info

Publication number
CY1110246T1
CY1110246T1 CY20101100665T CY101100665T CY1110246T1 CY 1110246 T1 CY1110246 T1 CY 1110246T1 CY 20101100665 T CY20101100665 T CY 20101100665T CY 101100665 T CY101100665 T CY 101100665T CY 1110246 T1 CY1110246 T1 CY 1110246T1
Authority
CY
Cyprus
Prior art keywords
alkyl
hydrogen
optionally substituted
och
hydroxy
Prior art date
Application number
CY20101100665T
Other languages
English (en)
Inventor
Klaus Dr Schiene
Günter Haase
Babette-Yvonne Dr Kögel
Elmar Dr Friiderichs
Ulrich Dr Jahnel
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32395002&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110246(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10254785A external-priority patent/DE10254785A1/de
Priority claimed from DE2003126103 external-priority patent/DE10326103A1/de
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of CY1110246T1 publication Critical patent/CY1110246T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Abstract

Χρησιμοποίηση (1R,2R)-3(3-διμεθυλαμινο-1-αιθυλο-προπυλο)-φαινόλης για τη θεραπεία φλεγμονώδους πόνου.
CY20101100665T 2002-11-22 2010-07-15 Χρησιμοποιηση (1r,2r)-3(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης για τη θεραπεια φλεγμονωδους πονου CY1110246T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10254785A DE10254785A1 (de) 2002-11-22 2002-11-22 Kombination ausgewählter Analgetika mit COX II-Inhibitoren
DE2003126103 DE10326103A1 (de) 2003-06-06 2003-06-06 Kombination ausgewählter Analgetika mit COX II-Inhibitoren
EP07014417A EP1839654B9 (de) 2002-11-22 2003-11-18 Verwendung von (1R, 2R)-3-(3-Dimenthylamino-1-ethyl-2-methyl-propyl)-phenol zur Behandlung von Entzündungsschmerz

Publications (1)

Publication Number Publication Date
CY1110246T1 true CY1110246T1 (el) 2015-01-14

Family

ID=32395002

Family Applications (4)

Application Number Title Priority Date Filing Date
CY20081100631T CY1108141T1 (el) 2002-11-22 2008-06-12 Χρησιμοποιηση (1rs,3rs,6rs)-6-διμεθυλαμινομεθυλο-1-(3-μεθοξυφαινυλο)-κυκλοεξανο-1,3-διολης για τη θεραπεια φλεγμονωδους πονου
CY20101100665T CY1110246T1 (el) 2002-11-22 2010-07-15 Χρησιμοποιηση (1r,2r)-3(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης για τη θεραπεια φλεγμονωδους πονου
CY20171100762T CY1119082T1 (el) 2002-11-22 2017-07-18 Συνδυασμος επιλεγμενων αναλγητικων με αναστολεις cox ii
CY20201100793T CY1123286T1 (el) 2002-11-22 2020-08-25 Χρηση (1r,2r)-3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολης για την αγωγη του φλεγμονωδους πονου

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20081100631T CY1108141T1 (el) 2002-11-22 2008-06-12 Χρησιμοποιηση (1rs,3rs,6rs)-6-διμεθυλαμινομεθυλο-1-(3-μεθοξυφαινυλο)-κυκλοεξανο-1,3-διολης για τη θεραπεια φλεγμονωδους πονου

Family Applications After (2)

Application Number Title Priority Date Filing Date
CY20171100762T CY1119082T1 (el) 2002-11-22 2017-07-18 Συνδυασμος επιλεγμενων αναλγητικων με αναστολεις cox ii
CY20201100793T CY1123286T1 (el) 2002-11-22 2020-08-25 Χρηση (1r,2r)-3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολης για την αγωγη του φλεγμονωδους πονου

Country Status (13)

Country Link
US (7) US7786160B2 (el)
EP (6) EP3241550B1 (el)
AT (2) ATE391498T1 (el)
AU (1) AU2003283410A1 (el)
CY (4) CY1108141T1 (el)
DE (2) DE50312678D1 (el)
DK (4) DK1685829T3 (el)
ES (4) ES2819854T3 (el)
HU (2) HUE033042T2 (el)
LT (1) LT1562567T (el)
PT (4) PT1685829E (el)
SI (4) SI1685829T1 (el)
WO (1) WO2004047823A1 (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3241550B1 (de) 2002-11-22 2020-07-22 Grünenthal GmbH (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol zur behandlung von entzündungsschmerz
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen
PL2012763T3 (pl) * 2006-04-28 2011-08-31 Gruenenthal Gmbh Kombinacja farmaceutyczna zawierająca 3-(3-dimetyloamino-1-etylo-2-metylo-propylo)-fenol i NSAID
CA2650423C (en) * 2006-04-28 2014-08-12 Gruenenthal Gmbh Pharmaceutical combination comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol and paracetamol
US20070254960A1 (en) * 2006-04-28 2007-11-01 Gruenenthal Gmbh Pharmaceutical combination
DE102007012165A1 (de) * 2007-03-12 2008-09-18 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
DE102007022790A1 (de) * 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose
NZ601529A (en) * 2007-11-23 2014-06-27 Gruenenthal Chemie Tapentadol compositions
EP2085081A1 (de) * 2008-02-04 2009-08-05 Grünenthal GmbH 3-(2-Dimethylaminomethyl-cyclohexyl)-phenol gegen polyneuropathischen Schmerz
KR20110059634A (ko) * 2008-09-05 2011-06-02 그뤼넨탈 게엠베하 6-디메틸아미노메틸-1-(3-메톡시-페닐)-사이클로헥산-1,3디올 및 파라세타몰을 포함하는 약제학적 병용물
RU2011112445A (ru) * 2008-09-05 2012-10-10 Грюненталь ГмбХ (DE) Фармацевтическая комбинация, которая содержит 6-диметиламинометил-1-(3-метоксифенил)-циклогексан-1,3-диол и нпвс
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
PT2352494T (pt) * 2008-10-30 2019-11-15 Gruenenthal Gmbh Novas e potentes formas de dosagem de tapentadol
WO2010124856A1 (en) * 2009-04-30 2010-11-04 Grünenthal GmbH Use of 1-phenyl-3-dimethylaminopropane compounds for treating rheumatoid pain
WO2011023392A1 (en) * 2009-08-28 2011-03-03 Grünenthal GmbH Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol or 6-dimethylaminomethyl-1-(3-hydroxy-phenyl)-cyclohexane-1,3-diol and an antiepileptic
CN104276960B (zh) * 2014-09-26 2016-09-28 安徽省逸欣铭医药科技有限公司 盐酸他喷他多和塞来昔布共晶及其组合物和制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4612008A (en) 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US5516803A (en) * 1991-10-30 1996-05-14 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
US5472711A (en) 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
US5330761A (en) 1993-01-29 1994-07-19 Edward Mendell Co. Inc. Bioadhesive tablet for non-systemic use products
US5455046A (en) 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5399362A (en) 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
DE4425459C2 (de) 1994-07-19 1997-11-27 Meinecke Ag H Woltmannzähler
IT1276322B1 (it) 1994-07-21 1997-10-28 Vbc Srl Procedimento per la purificazione dell'idrossido di magnesio
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
RS49982B (sr) 1997-09-17 2008-09-29 Euro-Celtique S.A., Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
EP0945134A1 (de) 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
ES2141688B1 (es) * 1998-11-06 2001-02-01 Vita Invest Sa Nuevos esteres derivados de compuestos fenil-ciclohexil sustituidos.
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
CN1349423A (zh) * 1999-03-01 2002-05-15 奥索-麦克尼尔药品公司 包含曲马多物质和选择性cox－2抑制剂药物的组合物
BR0008059A (pt) 1999-12-08 2002-03-26 Pharmacia Corp Composições de valdecoxib
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
MY120279A (en) 2000-05-26 2005-09-30 Pharmacia Corp Use of a celecoxib composition for fast pain relief
DE10049483A1 (de) 2000-09-29 2002-05-02 Gruenenthal Gmbh Substituierte 1-Aminobutan-3-ol-Derivate
DE10059411A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10059412A1 (de) 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie der Harninkontinenz
DE10109763A1 (de) * 2001-02-28 2002-09-05 Gruenenthal Gmbh Pharmazeutische Salze
UA78529C2 (en) * 2001-10-10 2007-04-10 Wyeth Corp Derivatives of [[2-(amino-3,4-dioxo-1-cyclobutene-1-yl)amino]alkyl] acid for treating pain
PE20030527A1 (es) * 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
DE10225315A1 (de) * 2002-06-06 2003-12-24 Gruenenthal Gmbh Wirkstoffsalze und Ester von 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl- pentan-3-ol und 3-(3-Dimethylamino-1-ethyl-1-hydroxy-2-methyl- propyl)-phenol
DE10250083A1 (de) * 2002-06-17 2003-12-24 Gruenenthal Gmbh Gegen Missbrauch gesicherte Darreichungsform
DE10233048A1 (de) * 2002-07-19 2004-01-29 Grünenthal GmbH Verwendung von 1-Phenyl-3dimethylamino-propanverbindungen zur Therapie von depressiven Symptomatiken
EP3241550B1 (de) 2002-11-22 2020-07-22 Grünenthal GmbH (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol zur behandlung von entzündungsschmerz

Also Published As

Publication number Publication date
AU2003283410A1 (en) 2004-06-18
PT1562567T (pt) 2017-08-24
EP3241550A1 (de) 2017-11-08
DK1839654T3 (da) 2010-08-16
US20130109733A1 (en) 2013-05-02
EP1839654A3 (de) 2007-11-07
HUE033042T2 (en) 2017-11-28
EP1839654B9 (de) 2012-01-11
PT1685829E (pt) 2008-05-15
EP1685829A1 (de) 2006-08-02
US7786160B2 (en) 2010-08-31
US20070249724A1 (en) 2007-10-25
DE50309605D1 (de) 2008-05-21
US20100280017A1 (en) 2010-11-04
US20100280129A1 (en) 2010-11-04
ATE465726T1 (de) 2010-05-15
US20050277687A1 (en) 2005-12-15
EP1839654B1 (de) 2010-04-28
EP1908460A1 (de) 2008-04-09
DK1562567T3 (en) 2017-07-17
EP1839654A2 (de) 2007-10-03
EP1562567B1 (de) 2017-06-14
ATE391498T1 (de) 2008-04-15
LT1562567T (lt) 2017-08-25
DK1685829T3 (da) 2008-07-21
CY1119082T1 (el) 2018-01-10
US20160279150A1 (en) 2016-09-29
CY1108141T1 (el) 2014-04-09
ES2345062T3 (es) 2010-09-14
EP3241550B1 (de) 2020-07-22
DE50312678D1 (de) 2010-06-10
DK3241550T3 (da) 2020-08-24
US20100280126A1 (en) 2010-11-04
PT3241550T (pt) 2020-08-11
HUE051024T2 (hu) 2021-03-01
ES2819854T3 (es) 2021-04-19
WO2004047823A1 (de) 2004-06-10
US8003701B2 (en) 2011-08-23
US8420691B2 (en) 2013-04-16
SI1839654T1 (sl) 2010-08-31
SI3241550T1 (sl) 2020-11-30
SI1562567T1 (sl) 2017-09-29
PT1839654E (pt) 2010-07-06
EP3662904A1 (de) 2020-06-10
EP1562567A1 (de) 2005-08-17
ES2304659T3 (es) 2008-10-16
US8404749B2 (en) 2013-03-26
CY1123286T1 (el) 2021-12-31
EP1685829B1 (de) 2008-04-09
US8618177B2 (en) 2013-12-31
US10471079B2 (en) 2019-11-12
SI1685829T1 (sl) 2008-08-31
ES2640404T3 (es) 2017-11-02

Similar Documents

Publication Publication Date Title
CY1123286T1 (el) Χρηση (1r,2r)-3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολης για την αγωγη του φλεγμονωδους πονου
HRP20110078T1 (hr) Postupak reduciranja alfa, beta nezasićenih ketona u opioidnim sastavima
BR0210468A (pt) Derivados 6-(aril-amido ou aril-amidometil)-naftalen-2-ilóxi-acìdicos como inibidores de inibidor de ativador de plasminogênio tipo-1 (pai-1)
AR012660A1 (es) Uso de compuestos de quinazolina para la manufactura de un medicamento util para el tratamiento de enfermedades poliquisticas del rinon.
MXPA02005604A (es) Aminobenzofenonas como inhibidores de il-1beta y tnf-alfa.
HK1125648A1 (en) Aminoacid derivatives containing a disulfanyl group in the form of mixed disulfanyl and aminopeptidase n inhibitors
RS49684B (sr) Upotreba derivata 7-(2-oksa-5,8- diazabiciklo[4.3.0]non-8-il)-hinolon- karbonske kiseline i nafthiridonkarbonske kiseline za pripremanje leka za terapiju helikobakter-pilori infekcija i sa time povezanim gastroduodenalnim oboljenjima
RU2008146816A (ru) Фармацевтическая комбинация, содержащая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и парацетамол
DE602005016659D1 (de) Wässrige zusammensetzung mit einem thiazol-derivat
RU2006102355A (ru) Средство, снижающее содержание холестерина в сыворотке крови, или средство для предотвращения или терапии атеросклероза
DE602005009126D1 (de) Benzoxazine zur vorbeugung oder behandlung der durch morphinderivaten verursachte hyperalgesia
PE20011079A1 (es) Derivados de acido 1,2,3,4-tetrahidroquinolin-2-carboxilico sustituidos, procedimientos para su preparacion, y composiciones que los comprenden
BRPI0513943A (pt) uso de um composto ou de um sal farmaceuticamente aceitável
AR040203A1 (es) Combinacion de un inhibidor del reflujo y una imidazopiridina para el tratamiento de la gerd
AR053122A1 (es) Monohidrato de di-s-camsilato de 5((2r,5s)-5-metil-4-propilmorfolin-2-il)piridin-2-amina, agonista de dopamina
AR012124A1 (es) Un procedimiento para la preparacion de derivados de tiazolidinadiona, derivados de tiazolidinadiona, su uso y preparados farmaceuticos que contienen a dichos derivados.
AR009484A1 (es) Un compuesto de acido n-sustituido-2-amino-4-fenil-4-oxo-butanoico, su utilizacion como inhibidor de la quinurenina-3-hidroxilasa y una composicionfarmaceutica que lo comprende.
AR052263A1 (es) Derivado de diazabiciclononeno
ATE500833T1 (de) Pharmazeutische zusammensetzungen zur verhütung oder behandlung von hirnödemen
GB0412865D0 (en) Chemical compounds
DE502005003538D1 (de) Herstellung von fluorierten 1,3-Benzodioxanen
TH70879A (th) อนุพันธ์ของ 5-(ไพริดิน-3-อิล)-1-แอซาไบไซโคล[3.2.1]ออกเทน, การเตรียมสาร และการประยุกต์ใช้สารในการบำบัดรักษา
TW351667B (en) Antibacterial-antifungal composition
RU99100316A (ru) Новые производные аминокислот и их применение в качестве ингибиторов тромбина
UY25608A1 (es) Procedimiento e intermedios para preparar naftiridonas