TR199701048T1 - Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�. - Google Patents

Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�.

Info

Publication number
TR199701048T1
TR199701048T1 TR97/01048T TR9701048T TR199701048T1 TR 199701048 T1 TR199701048 T1 TR 199701048T1 TR 97/01048 T TR97/01048 T TR 97/01048T TR 9701048 T TR9701048 T TR 9701048T TR 199701048 T1 TR199701048 T1 TR 199701048T1
Authority
TR
Turkey
Prior art keywords
fumagilol
rlanmas
revlerinin
kullan
enfeksiyonlar
Prior art date
Application number
TR97/01048T
Other languages
English (en)
Turkish (tr)
Inventor
Molina Jean-Michel
Derouin Francis
Original Assignee
Sanofi
Assistance Publique-Hopitaux De Paris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi, Assistance Publique-Hopitaux De Paris filed Critical Sanofi
Publication of TR199701048T1 publication Critical patent/TR199701048T1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TR97/01048T 1995-03-27 1996-03-26 Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�. TR199701048T1 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9503549 1995-03-27

Publications (1)

Publication Number Publication Date
TR199701048T1 true TR199701048T1 (xx) 1998-01-21

Family

ID=9477436

Family Applications (1)

Application Number Title Priority Date Filing Date
TR97/01048T TR199701048T1 (xx) 1995-03-27 1996-03-26 Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�.

Country Status (25)

Country Link
US (1) US5900431A (enExample)
EP (1) EP0817626B1 (enExample)
JP (1) JP3260378B2 (enExample)
KR (1) KR100286920B1 (enExample)
CN (1) CN1072485C (enExample)
AP (1) AP646A (enExample)
AT (1) ATE172641T1 (enExample)
AU (1) AU706161B2 (enExample)
CA (1) CA2216623C (enExample)
CZ (1) CZ286821B6 (enExample)
DE (1) DE69600879T2 (enExample)
DK (1) DK0817626T3 (enExample)
EA (1) EA000150B1 (enExample)
ES (1) ES2128846T3 (enExample)
FR (1) FR06C0014I2 (enExample)
HU (1) HU224028B1 (enExample)
IS (1) IS2048B (enExample)
NO (1) NO315968B1 (enExample)
NZ (1) NZ304906A (enExample)
OA (1) OA10515A (enExample)
PL (1) PL183378B1 (enExample)
SK (1) SK283883B6 (enExample)
TR (1) TR199701048T1 (enExample)
UA (1) UA41446C2 (enExample)
WO (1) WO1996030010A2 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP646A (en) * 1995-03-27 1998-04-27 Sanofi Synthelabo Use of fumagillol and derivatives thereof for preparing medicaments against intestinal infections.
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
DK1156829T3 (da) * 1999-02-26 2007-09-10 Sanofi Aventis Stabil formulering indeholdende fumagillin
JP3265394B1 (ja) * 2001-03-14 2002-03-11 泰三 矢野 アクリル系樹脂手袋
DE10341887A1 (de) * 2003-09-09 2005-03-31 Leopold Kostal Gmbh & Co. Kg Elektrisches Schaltermodul
FR2886855B1 (fr) * 2005-06-08 2009-07-17 Agronomique Inst Nat Rech Utilisation de la fumagilline et de ses derives pour augmenter la biodisponibilite des lactones macrocyliques
EA020251B1 (ru) * 2007-11-28 2014-09-30 Мерсана Терапьютикс, Инк. Биосовместимые и биоразлагаемые конъюгаты аналогов фумагиллина
CA2731020A1 (en) * 2008-07-18 2010-01-21 Zafgen, Inc. Use of antiangiogenic fumagillins in the treatment of obesity
WO2010065883A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Method of treating an overweight or obese subject
US20120004162A1 (en) 2008-12-04 2012-01-05 Vath James E Methods of Treating an Overweight or Obese Subject
KR20120083905A (ko) 2009-10-09 2012-07-26 자프겐 코포레이션 비만의 치료에 사용하기 위한 설폰 화합물
WO2011085198A1 (en) 2010-01-08 2011-07-14 Zafgen Corporation Metap-2 inhibitor for use in treating benign prostatic hypertrophy (bph)
CA2786603C (en) 2010-01-08 2018-02-20 James E. Vath Fumagillol type compounds and methods of making and using same
WO2011127304A2 (en) 2010-04-07 2011-10-13 Zafgen Corporation Methods of treating an overweight subject
KR20130043207A (ko) 2010-07-22 2013-04-29 자프겐 인크. 트리시클릭 화합물 및 이의 제조 및 사용 방법
PH12013500934A1 (en) 2010-11-09 2022-10-24 Zafgen Inc Crystalline solids of a metap-2 inhibitor and methods of making and using same
CA2819251A1 (en) 2010-11-29 2012-06-07 Zafgen Corporation Treatment of obesity using non-daily administration of 6 - 0 - (4 - dimethylaminoethoxy) cinnamoyl fumagillol
CA2825408A1 (en) 2011-01-26 2012-08-02 Zafgen, Inc. Tetrazole compounds and methods of making and using same
JP5876513B2 (ja) 2011-03-08 2016-03-02 ザフゲン,インコーポレイテッド オキサスピロ[2.5]オクタン誘導体および類似体
BR112013028666A2 (pt) 2011-05-06 2017-08-08 Zafgen Inc compostos de pirazolo sulfonamida tricícilos e métodos para fazer e usar o mesmo
BR112013028665A2 (pt) 2011-05-06 2016-09-06 Zafgen Inc compostos de sulfonamida tricíclicos e métodos para fazer e usar os mesmos
KR101979039B1 (ko) 2011-05-06 2019-05-15 자프겐 인크. 부분 포화된 삼환식 화합물 및 그리고 그의 제조방법 및 그를 이용하는 방법
EP2763671A2 (en) 2011-10-03 2014-08-13 Zafgen, Inc. Methods of treating age related disorders
EP2804856B1 (en) 2012-01-18 2017-03-15 Zafgen, Inc. Tricyclic sulfone compounds and methods of making and using same
BR112014017673A8 (pt) 2012-01-18 2017-07-11 Zafgen Inc Compostos de sulfonamida tricíclicos e métodos para fazer e usar os mesmos
EP2847176A1 (en) 2012-05-07 2015-03-18 Zafgen, Inc. Polymorphic salt of the oxalate salt of 6 - o - ( 4 - dimethylaminoethoxy) cinnarnoyl fumagillol and methods of making and using same
BR112014028041A2 (pt) 2012-05-08 2017-06-27 Zafgen Inc tratamento de obesidade hipotalâmica com inibidores de metap2
CA2873574A1 (en) 2012-05-09 2013-11-14 Zafgen, Inc. Fumagillol type compounds and methods of making and using same
CN104918615B (zh) 2012-11-05 2018-10-12 扎夫根股份有限公司 治疗肝病的方法
US9868717B2 (en) 2012-11-05 2018-01-16 Zafgen, Inc. Tricyclic sulphonamide compounds and methods of making and using same
BR112015010225A2 (pt) 2012-11-05 2017-07-11 Zafgen Inc compostos tricíclicos e seus métodos de produção e utilização
AU2014236528A1 (en) 2013-03-14 2015-09-24 Zafgen, Inc. Methods of treating renal disease and other disorders
AR105671A1 (es) 2015-08-11 2017-10-25 Zafgen Inc Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso
CN106432255A (zh) 2015-08-11 2017-02-22 扎夫根公司 烟曲霉素醇螺环化合物和制备和使用其的方法
CN106591389B (zh) * 2015-10-15 2019-10-11 中国科学院微生物研究所 一种利用烟曲霉菌生产烟曲霉素的方法
CN105622593B (zh) * 2016-02-25 2018-06-26 中国农业科学院蜜蜂研究所 一种烟曲霉素的提取方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2791530A (en) * 1953-08-31 1957-05-07 Abbott Lab Stabilized fumagillin compositions
JPH0629278B2 (ja) * 1985-06-26 1994-04-20 藤沢薬品工業株式会社 オキサスピロオクタン化合物
US5135920A (en) * 1988-11-16 1992-08-04 Takeda Chemical Industries, Ltd. Angiostatic agents
CA2082804A1 (en) * 1990-07-27 1992-01-28 Theodore Maione Methods and compositions for treatment of angiogenic diseases
US5328930A (en) 1993-03-01 1994-07-12 Emory University Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin
AP646A (en) * 1995-03-27 1998-04-27 Sanofi Synthelabo Use of fumagillol and derivatives thereof for preparing medicaments against intestinal infections.
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
CA2210600A1 (en) * 1996-07-17 1998-01-17 Takashi Houkan Inhibitor of tumor metastasis or recurrence
WO1998005293A2 (en) * 1996-08-02 1998-02-12 The Children's Medical Center Corporation Method of regulating the female reproductive system through angiogenesis inhibitors

Also Published As

Publication number Publication date
DE69600879D1 (de) 1998-12-03
CZ286821B6 (en) 2000-07-12
WO1996030010A3 (fr) 1996-11-28
CA2216623A1 (en) 1996-10-03
DE69600879T2 (de) 1999-06-02
PL322470A1 (en) 1998-02-02
CN1179715A (zh) 1998-04-22
FR06C0014I1 (enExample) 2006-11-17
EP0817626B1 (fr) 1998-10-28
NO974466L (no) 1997-09-26
HUP9801220A2 (hu) 1999-09-28
AP9701092A0 (en) 1997-10-31
US5900431A (en) 1999-05-04
EA000150B1 (ru) 1998-10-29
NZ304906A (en) 1999-06-29
CN1072485C (zh) 2001-10-10
OA10515A (fr) 2002-04-24
ATE172641T1 (de) 1998-11-15
CZ304997A3 (en) 1997-12-17
IS2048B (is) 2005-09-15
MX9707150A (es) 1998-07-31
AU706161B2 (en) 1999-06-10
SK130797A3 (en) 1998-03-04
SK283883B6 (sk) 2004-04-06
UA41446C2 (uk) 2001-09-17
IS4557A (is) 1997-09-11
NO315968B1 (no) 2003-11-24
AU5278696A (en) 1996-10-16
PL183378B1 (pl) 2002-06-28
HUP9801220A3 (en) 2001-10-29
KR19980703271A (ko) 1998-10-15
JP3260378B2 (ja) 2002-02-25
WO1996030010A2 (fr) 1996-10-03
EP0817626A2 (fr) 1998-01-14
NO974466D0 (no) 1997-09-26
FR06C0014I2 (enExample) 2006-12-29
HU224028B1 (hu) 2005-05-30
CA2216623C (en) 2005-05-31
KR100286920B1 (ko) 2001-04-16
DK0817626T3 (da) 1999-07-12
ES2128846T3 (es) 1999-05-16
AP646A (en) 1998-04-27
JPH11506421A (ja) 1999-06-08
EA199700267A1 (ru) 1998-04-30

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