ATE172641T1 - Verwendung von fumagillol und seinen derivaten zur herstellung von arzneimitteln gegen darminfektionen - Google Patents
Verwendung von fumagillol und seinen derivaten zur herstellung von arzneimitteln gegen darminfektionenInfo
- Publication number
- ATE172641T1 ATE172641T1 AT96909200T AT96909200T ATE172641T1 AT E172641 T1 ATE172641 T1 AT E172641T1 AT 96909200 T AT96909200 T AT 96909200T AT 96909200 T AT96909200 T AT 96909200T AT E172641 T1 ATE172641 T1 AT E172641T1
- Authority
- AT
- Austria
- Prior art keywords
- fumagillol
- derivatives
- production
- medicinal products
- products against
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9503549 | 1995-03-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE172641T1 true ATE172641T1 (de) | 1998-11-15 |
Family
ID=9477436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96909200T ATE172641T1 (de) | 1995-03-27 | 1996-03-26 | Verwendung von fumagillol und seinen derivaten zur herstellung von arzneimitteln gegen darminfektionen |
Country Status (25)
Country | Link |
---|---|
US (1) | US5900431A (de) |
EP (1) | EP0817626B1 (de) |
JP (1) | JP3260378B2 (de) |
KR (1) | KR100286920B1 (de) |
CN (1) | CN1072485C (de) |
AP (1) | AP646A (de) |
AT (1) | ATE172641T1 (de) |
AU (1) | AU706161B2 (de) |
CA (1) | CA2216623C (de) |
CZ (1) | CZ286821B6 (de) |
DE (1) | DE69600879T2 (de) |
DK (1) | DK0817626T3 (de) |
EA (1) | EA000150B1 (de) |
ES (1) | ES2128846T3 (de) |
FR (1) | FR06C0014I2 (de) |
HU (1) | HU224028B1 (de) |
IS (1) | IS2048B (de) |
NO (1) | NO315968B1 (de) |
NZ (1) | NZ304906A (de) |
OA (1) | OA10515A (de) |
PL (1) | PL183378B1 (de) |
SK (1) | SK283883B6 (de) |
TR (1) | TR199701048T1 (de) |
UA (1) | UA41446C2 (de) |
WO (1) | WO1996030010A2 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL183378B1 (pl) * | 1995-03-27 | 2002-06-28 | Assist Publ Hopitaux De Paris | Zastosowanie fumagilolu i jego pochodnych do wytwarzania jelitowych środków przeciwinfekcyjnych |
EP0799616A1 (de) * | 1996-04-01 | 1997-10-08 | Takeda Chemical Industries, Ltd. | Orale Zubereitung enthaltend ein Fumagillolderivat |
DK1156829T3 (da) * | 1999-02-26 | 2007-09-10 | Sanofi Aventis | Stabil formulering indeholdende fumagillin |
JP3265394B1 (ja) * | 2001-03-14 | 2002-03-11 | 泰三 矢野 | アクリル系樹脂手袋 |
DE10341887A1 (de) * | 2003-09-09 | 2005-03-31 | Leopold Kostal Gmbh & Co. Kg | Elektrisches Schaltermodul |
FR2886855B1 (fr) * | 2005-06-08 | 2009-07-17 | Agronomique Inst Nat Rech | Utilisation de la fumagilline et de ses derives pour augmenter la biodisponibilite des lactones macrocyliques |
EP2217283A2 (de) * | 2007-11-28 | 2010-08-18 | Mersana Therapeutics, Inc. | Biokompatible, biologisch abbaubare fumagillin-analogkonjugate |
US8865746B2 (en) * | 2008-07-18 | 2014-10-21 | Zafgen, Inc. | Methods of treating an overweight or obese subject |
US8642650B2 (en) | 2008-12-04 | 2014-02-04 | Zafgen, Inc. | Methods of treating an overweight or obese subject |
US20120004162A1 (en) | 2008-12-04 | 2012-01-05 | Vath James E | Methods of Treating an Overweight or Obese Subject |
WO2013055385A2 (en) | 2011-10-03 | 2013-04-18 | Zafgen Corporation | Methods of treating age related disorders |
MX337575B (es) | 2009-10-09 | 2016-03-10 | Zafgen Corp | Compuestos de sulfona y métodos para lafabricación y uso de éstos. |
BR112012016793A2 (pt) | 2010-01-08 | 2018-07-31 | Zafgen Corp | compostos tipo fumagilol e métodos de fazer e usar os mesmos |
WO2011085198A1 (en) | 2010-01-08 | 2011-07-14 | Zafgen Corporation | Metap-2 inhibitor for use in treating benign prostatic hypertrophy (bph) |
WO2011127304A2 (en) | 2010-04-07 | 2011-10-13 | Zafgen Corporation | Methods of treating an overweight subject |
KR20130043207A (ko) | 2010-07-22 | 2013-04-29 | 자프겐 인크. | 트리시클릭 화합물 및 이의 제조 및 사용 방법 |
KR101892768B1 (ko) | 2010-11-09 | 2018-08-28 | 자프겐 인크. | Metap-2 저해제의 결정질 고체 및 그의 제조 및 이용 방법 |
WO2012075020A1 (en) | 2010-11-29 | 2012-06-07 | Zafgen Corporation | Treatment of obesity using non-daily administration of 6 - 0 - (4 - dimethylaminoethoxy) cinnamoyl fumagillol |
MX344238B (es) | 2011-01-26 | 2016-12-07 | Zafgen Inc | Compuestos de tetrazol y métodos para preparar y usar los mismos. |
CN103534244B (zh) | 2011-03-08 | 2016-10-12 | 扎夫根股份有限公司 | 氧杂螺[2.5]辛烷衍生物及类似物 |
WO2012154678A1 (en) | 2011-05-06 | 2012-11-15 | Zafgen Corporation | Tricyclic sulfonamide compounds and methods of making and using same |
AU2012253760B2 (en) | 2011-05-06 | 2016-02-04 | Zafgen, Inc. | Tricyclic pyrazole sulfonamide compounds and methods of making and using same |
BR112013028534A2 (pt) | 2011-05-06 | 2016-09-06 | Zafgen Inc | compostos tricíclicos parcialmente saturados e métodos para produção e utilização dos mesmos |
AU2013209723B2 (en) | 2012-01-18 | 2016-11-24 | Zafgen, Inc. | Tricyclic sulfonamide compounds and methods of making and using same |
US9440943B2 (en) | 2012-01-18 | 2016-09-13 | Zafgen, Inc. | Tricyclic sulfone compounds and methods of making and using same |
US9260419B2 (en) | 2012-05-07 | 2016-02-16 | Zafgen, Inc. | Polymorphic salt of a metap-2 inhibitor and methods of making and using same |
CN104363905A (zh) | 2012-05-08 | 2015-02-18 | 扎夫根股份有限公司 | 用metap2抑制剂治疗下丘脑性肥胖 |
EP2850079B1 (de) | 2012-05-09 | 2018-05-02 | Zafgen, Inc. | Fumigillol derivate,verfahren zu deren herstellung und deren verwendung |
MX2015005733A (es) | 2012-11-05 | 2016-02-10 | Zafgen Inc | Compuestos triciclicos para usarse en el tratamiento y/o control de obesidad. |
AU2013337282A1 (en) | 2012-11-05 | 2015-05-21 | Zafgen, Inc. | Tricyclic compounds and methods of making and using same |
NZ707773A (en) | 2012-11-05 | 2019-05-31 | Zafgen Inc | Methods of treating liver diseases |
EP2968250B1 (de) | 2013-03-14 | 2019-06-19 | Zafgen, Inc. | Verfahren zur behandlung von nierenerkrankungen und anderen störungen |
CN106432255A (zh) | 2015-08-11 | 2017-02-22 | 扎夫根公司 | 烟曲霉素醇螺环化合物和制备和使用其的方法 |
AR105671A1 (es) | 2015-08-11 | 2017-10-25 | Zafgen Inc | Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso |
CN106591389B (zh) * | 2015-10-15 | 2019-10-11 | 中国科学院微生物研究所 | 一种利用烟曲霉菌生产烟曲霉素的方法 |
CN105622593B (zh) * | 2016-02-25 | 2018-06-26 | 中国农业科学院蜜蜂研究所 | 一种烟曲霉素的提取方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2791530A (en) * | 1953-08-31 | 1957-05-07 | Abbott Lab | Stabilized fumagillin compositions |
JPH0629278B2 (ja) * | 1985-06-26 | 1994-04-20 | 藤沢薬品工業株式会社 | オキサスピロオクタン化合物 |
US5135920A (en) * | 1988-11-16 | 1992-08-04 | Takeda Chemical Industries, Ltd. | Angiostatic agents |
EP0541716A1 (de) * | 1990-07-27 | 1993-05-19 | Repligen Corporation | Neuartige methoden und zusammensetzungen zur behandlung von gefässerkrankungen |
US5328930A (en) * | 1993-03-01 | 1994-07-12 | Emory University | Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin |
PL183378B1 (pl) * | 1995-03-27 | 2002-06-28 | Assist Publ Hopitaux De Paris | Zastosowanie fumagilolu i jego pochodnych do wytwarzania jelitowych środków przeciwinfekcyjnych |
EP0799616A1 (de) * | 1996-04-01 | 1997-10-08 | Takeda Chemical Industries, Ltd. | Orale Zubereitung enthaltend ein Fumagillolderivat |
CA2210600A1 (en) * | 1996-07-17 | 1998-01-17 | Takashi Houkan | Inhibitor of tumor metastasis or recurrence |
WO1998005293A2 (en) * | 1996-08-02 | 1998-02-12 | The Children's Medical Center Corporation | Method of regulating the female reproductive system through angiogenesis inhibitors |
-
1996
- 1996-03-26 PL PL96322470A patent/PL183378B1/pl unknown
- 1996-03-26 AT AT96909200T patent/ATE172641T1/de active
- 1996-03-26 JP JP52900196A patent/JP3260378B2/ja not_active Expired - Lifetime
- 1996-03-26 TR TR97/01048T patent/TR199701048T1/xx unknown
- 1996-03-26 KR KR1019970706675A patent/KR100286920B1/ko not_active IP Right Cessation
- 1996-03-26 CZ CZ19973049A patent/CZ286821B6/cs not_active IP Right Cessation
- 1996-03-26 DE DE69600879T patent/DE69600879T2/de not_active Expired - Lifetime
- 1996-03-26 CA CA002216623A patent/CA2216623C/en not_active Expired - Lifetime
- 1996-03-26 US US08/913,360 patent/US5900431A/en not_active Expired - Lifetime
- 1996-03-26 EA EA199700267A patent/EA000150B1/ru not_active IP Right Cessation
- 1996-03-26 ES ES96909200T patent/ES2128846T3/es not_active Expired - Lifetime
- 1996-03-26 AP APAP/P/1997/001092A patent/AP646A/en active
- 1996-03-26 EP EP96909200A patent/EP0817626B1/de not_active Expired - Lifetime
- 1996-03-26 DK DK96909200T patent/DK0817626T3/da active
- 1996-03-26 WO PCT/FR1996/000448 patent/WO1996030010A2/fr active IP Right Grant
- 1996-03-26 CN CN96192923A patent/CN1072485C/zh not_active Expired - Lifetime
- 1996-03-26 SK SK1307-97A patent/SK283883B6/sk not_active IP Right Cessation
- 1996-03-26 NZ NZ304906A patent/NZ304906A/xx not_active IP Right Cessation
- 1996-03-26 AU AU52786/96A patent/AU706161B2/en not_active Expired
- 1996-03-26 HU HU9801220A patent/HU224028B1/hu active IP Right Grant
- 1996-03-26 UA UA97094765A patent/UA41446C2/uk unknown
-
1997
- 1997-09-11 IS IS4557A patent/IS2048B/is unknown
- 1997-09-26 OA OA70088A patent/OA10515A/fr unknown
- 1997-09-26 NO NO19974466A patent/NO315968B1/no not_active IP Right Cessation
-
2006
- 2006-04-04 FR FR06C0014C patent/FR06C0014I2/fr active Active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |