ES2070148T3 - Derivado de la glicerina y utilizacion farmacologica del mismo. - Google Patents

Derivado de la glicerina y utilizacion farmacologica del mismo.

Info

Publication number
ES2070148T3
ES2070148T3 ES89112204T ES89112204T ES2070148T3 ES 2070148 T3 ES2070148 T3 ES 2070148T3 ES 89112204 T ES89112204 T ES 89112204T ES 89112204 T ES89112204 T ES 89112204T ES 2070148 T3 ES2070148 T3 ES 2070148T3
Authority
ES
Spain
Prior art keywords
glycerin
derivative
same
pharmacological use
pharmacological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89112204T
Other languages
English (en)
Inventor
Kazuo Okano
Osamu Asano
Naoyuki Shimomura
Tetsuya Kawahara
Shinya Abe
Shuhei Miyazawa
Mitsuaki Miyamoto
Hiroyuki Yoshimura
Koukichi Harada
Junsaku Nagaoka
Tsutomu Kawata
Tsutomu Yoshimura
Hiromasa Suzuki
Shigeru Souda
Yoshimasa Machida
Kouichi Katayama
Isao Yamatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ES2070148T3 publication Critical patent/ES2070148T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

UN DERIVADO DE GLICERINA TENIENDO LA SIGUIENTE FORMULA (I) O (I'') Y UNA SAL FARMACOLOGICAMENTE ACEPTABLE DE ELLOS, TENIENDO USO EN EL TRATAMIENTO DE MALES CAUSADOS POR EL FACTOR DE ACTIVACION DE PLAQUETAS.
ES89112204T 1988-07-04 1989-07-04 Derivado de la glicerina y utilizacion farmacologica del mismo. Expired - Lifetime ES2070148T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16638688 1988-07-04

Publications (1)

Publication Number Publication Date
ES2070148T3 true ES2070148T3 (es) 1995-06-01

Family

ID=15830457

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89112204T Expired - Lifetime ES2070148T3 (es) 1988-07-04 1989-07-04 Derivado de la glicerina y utilizacion farmacologica del mismo.

Country Status (20)

Country Link
US (1) US5037827A (es)
EP (1) EP0353474B1 (es)
JP (1) JP2766319B2 (es)
KR (1) KR910006127B1 (es)
CN (1) CN1041920C (es)
AT (1) ATE120734T1 (es)
AU (1) AU621634B2 (es)
CA (1) CA1334753C (es)
DD (1) DD297814A5 (es)
DE (1) DE68922035T2 (es)
DK (1) DK329189A (es)
ES (1) ES2070148T3 (es)
FI (1) FI97883C (es)
GR (1) GR3015704T3 (es)
HU (2) HU208119B (es)
NO (1) NO177495C (es)
NZ (1) NZ229789A (es)
PH (1) PH26045A (es)
PT (1) PT91051B (es)
RU (1) RU2040521C1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5136040A (en) * 1991-02-26 1992-08-04 Eli Lilly And Company Preparation of substituted tetrahydropyridines
JP3298883B2 (ja) * 1992-06-30 2002-07-08 ポハン アイアン アンド スチール カンパニー リミテッド 強力なｐａｆ拮抗剤としての新規な環式脂質誘導体
US5700817A (en) * 1992-06-30 1997-12-23 Pohang Iron & Steel Co., Ltd. Cyclic lipid derivatives as potent PAF antagonists
JPH07285866A (ja) * 1994-02-22 1995-10-31 Eisai Co Ltd 臓器障害予防・治療・改善剤
US5854279A (en) * 1996-06-04 1998-12-29 Eisai Co., Ltd Therapeutic agent for dermatosis
US6177067B1 (en) 1996-08-09 2001-01-23 Shiseido Company, Ltd. Hair revitalizing tonic composition containing a 2,2-dimethylpropanediol compound and use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2965419D1 (en) * 1979-02-19 1983-07-07 Bbc Brown Boveri & Cie Exhaust-gas driven turbocharger having two stages
ZA8410014B (en) * 1983-12-30 1985-08-28 Hoffmann La Roche Glycerol derivatives
DK160818C (da) * 1983-12-30 1991-10-07 Hoffmann La Roche N-ring-holdige glycerolderivater, fremgangsmaade til fremstilling deraf, anvendelse deraf til fremstilling af et blodpladeaktiveringsfaktorhaemmende middel samt laegemidler indeholdende en saadan forbindelse
US4737518A (en) * 1984-04-03 1988-04-12 Takeda Chemical Industries, Ltd. Lipid derivatives, their production and use
DE3586746D1 (de) * 1984-04-03 1992-11-19 Takeda Chemical Industries Ltd Lipidderivate, ihre produktion und verwendung.
US4863941A (en) * 1985-06-18 1989-09-05 Hoffmann-La Roche Inc. Glycerol derivatives
JPH0815643B2 (ja) * 1988-05-19 1996-02-21 新日本製鐵株式会社 幅可変薄スラブ連続鋳造機の湯面レベル制御方法

Also Published As

Publication number Publication date
JPH02131467A (ja) 1990-05-21
DD297814A5 (de) 1992-01-23
CN1039414A (zh) 1990-02-07
EP0353474A2 (en) 1990-02-07
NO177495C (no) 1995-09-27
ATE120734T1 (de) 1995-04-15
HU9202211D0 (en) 1992-12-28
US5037827A (en) 1991-08-06
DK329189A (da) 1990-01-05
NO177495B (no) 1995-06-19
FI893099A (fi) 1990-01-05
AU3721389A (en) 1990-01-04
EP0353474A3 (en) 1991-03-27
FI893099A0 (fi) 1989-06-26
DE68922035D1 (de) 1995-05-11
CA1334753C (en) 1995-03-14
HU208119B (en) 1993-08-30
PH26045A (en) 1992-01-29
FI97883B (fi) 1996-11-29
PT91051A (pt) 1990-02-08
CN1041920C (zh) 1999-02-03
JP2766319B2 (ja) 1998-06-18
RU2040521C1 (ru) 1995-07-25
NO892743L (no) 1990-01-05
FI97883C (fi) 1997-03-10
DE68922035T2 (de) 1995-09-14
GR3015704T3 (en) 1995-07-31
HUT52478A (en) 1990-07-28
NO892743D0 (no) 1989-07-03
KR910006127B1 (ko) 1991-08-13
EP0353474B1 (en) 1995-04-05
KR900001654A (ko) 1990-02-27
PT91051B (pt) 1995-06-30
AU621634B2 (en) 1992-03-19
DK329189D0 (da) 1989-07-03
NZ229789A (en) 1991-04-26
HUT62855A (en) 1993-06-28

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