TR199701048T1 - Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�. - Google Patents

Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�.

Info

Publication number
TR199701048T1
TR199701048T1 TR97/01048T TR9701048T TR199701048T1 TR 199701048 T1 TR199701048 T1 TR 199701048T1 TR 97/01048 T TR97/01048 T TR 97/01048T TR 9701048 T TR9701048 T TR 9701048T TR 199701048 T1 TR199701048 T1 TR 199701048T1
Authority
TR
Turkey
Prior art keywords
fumagilol
rlanmas
revlerinin
kullan
enfeksiyonlar
Prior art date
Application number
TR97/01048T
Other languages
English (en)
Turkish (tr)
Inventor
Molina Jean-Michel
Derouin Francis
Original Assignee
Sanofi
Assistance Publique-Hopitaux De Paris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi, Assistance Publique-Hopitaux De Paris filed Critical Sanofi
Publication of TR199701048T1 publication Critical patent/TR199701048T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TR97/01048T 1995-03-27 1996-03-26 Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�. TR199701048T1 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9503549 1995-03-27

Publications (1)

Publication Number Publication Date
TR199701048T1 true TR199701048T1 (xx) 1998-01-21

Family

ID=9477436

Family Applications (1)

Application Number Title Priority Date Filing Date
TR97/01048T TR199701048T1 (xx) 1995-03-27 1996-03-26 Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�.

Country Status (25)

Country Link
US (1) US5900431A (en:Method)
EP (1) EP0817626B1 (en:Method)
JP (1) JP3260378B2 (en:Method)
KR (1) KR100286920B1 (en:Method)
CN (1) CN1072485C (en:Method)
AP (1) AP646A (en:Method)
AT (1) ATE172641T1 (en:Method)
AU (1) AU706161B2 (en:Method)
CA (1) CA2216623C (en:Method)
CZ (1) CZ286821B6 (en:Method)
DE (1) DE69600879T2 (en:Method)
DK (1) DK0817626T3 (en:Method)
EA (1) EA000150B1 (en:Method)
ES (1) ES2128846T3 (en:Method)
FR (1) FR06C0014I2 (en:Method)
HU (1) HU224028B1 (en:Method)
IS (1) IS2048B (en:Method)
NO (1) NO315968B1 (en:Method)
NZ (1) NZ304906A (en:Method)
OA (1) OA10515A (en:Method)
PL (1) PL183378B1 (en:Method)
SK (1) SK283883B6 (en:Method)
TR (1) TR199701048T1 (en:Method)
UA (1) UA41446C2 (en:Method)
WO (1) WO1996030010A2 (en:Method)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1072485C (zh) * 1995-03-27 2001-10-10 萨诺费合成实验室 夫马菌醇及其衍生物用于制备抗肠道感染药物的用途
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
DK1156829T3 (da) * 1999-02-26 2007-09-10 Sanofi Aventis Stabil formulering indeholdende fumagillin
JP3265394B1 (ja) * 2001-03-14 2002-03-11 泰三 矢野 アクリル系樹脂手袋
DE10341887A1 (de) * 2003-09-09 2005-03-31 Leopold Kostal Gmbh & Co. Kg Elektrisches Schaltermodul
FR2886855B1 (fr) * 2005-06-08 2009-07-17 Agronomique Inst Nat Rech Utilisation de la fumagilline et de ses derives pour augmenter la biodisponibilite des lactones macrocyliques
EP2217283A2 (en) * 2007-11-28 2010-08-18 Mersana Therapeutics, Inc. Biocompatible biodegradable fumagillin analog conjugates
NZ590732A (en) * 2008-07-18 2012-09-28 Zafgen Inc Methods of treating an overweight or obese subject using fumagillin
WO2010065883A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Method of treating an overweight or obese subject
WO2013055385A2 (en) 2011-10-03 2013-04-18 Zafgen Corporation Methods of treating age related disorders
US20120004162A1 (en) 2008-12-04 2012-01-05 Vath James E Methods of Treating an Overweight or Obese Subject
MX337575B (es) 2009-10-09 2016-03-10 Zafgen Corp Compuestos de sulfona y métodos para lafabricación y uso de éstos.
BR112012016793A2 (pt) 2010-01-08 2018-07-31 Zafgen Corp compostos tipo fumagilol e métodos de fazer e usar os mesmos
WO2011085198A1 (en) 2010-01-08 2011-07-14 Zafgen Corporation Metap-2 inhibitor for use in treating benign prostatic hypertrophy (bph)
US20130266578A1 (en) 2010-04-07 2013-10-10 Thomas E. Hughes Methods of treating an overweight subject
JP5913310B2 (ja) 2010-07-22 2016-04-27 ザフゲン，インコーポレイテッド 三環式化合物ならびにその作製および使用方法
PH12013500934A1 (en) 2010-11-09 2022-10-24 Zafgen Inc Crystalline solids of a metap-2 inhibitor and methods of making and using same
WO2012075020A1 (en) 2010-11-29 2012-06-07 Zafgen Corporation Treatment of obesity using non-daily administration of 6 - 0 - (4 - dimethylaminoethoxy) cinnamoyl fumagillol
KR20140006888A (ko) 2011-01-26 2014-01-16 자프겐 인크. 테트라졸화합물, 그리고, 이를 제조하는 방법 및 이를 이용하는 방법
BR112013023056A2 (pt) 2011-03-08 2018-10-09 Zafgen Inc derivados de oxaespiro [2,5] octano e análogos
WO2012154676A1 (en) 2011-05-06 2012-11-15 Zafgen Corporation Partially saturated tricyclic compounds and methods of making and using same
US9187494B2 (en) 2011-05-06 2015-11-17 Zafgen, Inc. Aryl-substituted tricyclic sulfonamides as methionyl aminopeptidase 2 modulators
MX343688B (es) 2011-05-06 2016-11-16 Zafgen Inc Compuestos tricíclicos de sulfonamida y pirazolo y métodos para su fabricación y uso.
EP2804856B1 (en) 2012-01-18 2017-03-15 Zafgen, Inc. Tricyclic sulfone compounds and methods of making and using same
EP2804866B1 (en) 2012-01-18 2016-11-16 Zafgen, Inc. Tricyclic sulfonamide compounds and methods of making and using same
KR20150016303A (ko) 2012-05-07 2015-02-11 자프겐 인크. 6-o-(4-디메틸아미노에톡시) 신나모일 푸마지롤의 옥살레이트 염의 다형체 염 및 이의 제조 및 사용 방법
EP2846792B1 (en) 2012-05-08 2018-08-15 Zafgen, Inc. Treating hypothalamic obesity with metap2 inhibitors
AU2013259620B2 (en) 2012-05-09 2017-05-18 Zafgen, Inc. Fumigillol type compounds and methods of making and using same
SG11201503521QA (en) 2012-11-05 2015-06-29 Zafgen Inc Methods of treating liver diseases
CA2890344A1 (en) 2012-11-05 2014-05-08 Zafgen, Inc. Tricyclic compounds for use in the treatment and/or control of obesity
CA2890342A1 (en) 2012-11-05 2014-05-08 Zafgen, Inc. Tricyclic compounds and methods of making and using same
US9597309B2 (en) 2013-03-14 2017-03-21 Zafgen, Inc. Methods of treating renal disease and other disorders
AR105671A1 (es) 2015-08-11 2017-10-25 Zafgen Inc Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso
CN106432255A (zh) 2015-08-11 2017-02-22 扎夫根公司 烟曲霉素醇螺环化合物和制备和使用其的方法
CN106591389B (zh) * 2015-10-15 2019-10-11 中国科学院微生物研究所 一种利用烟曲霉菌生产烟曲霉素的方法
CN105622593B (zh) * 2016-02-25 2018-06-26 中国农业科学院蜜蜂研究所 一种烟曲霉素的提取方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2791530A (en) * 1953-08-31 1957-05-07 Abbott Lab Stabilized fumagillin compositions
JPH0629278B2 (ja) * 1985-06-26 1994-04-20 藤沢薬品工業株式会社 オキサスピロオクタン化合物
US5135920A (en) * 1988-11-16 1992-08-04 Takeda Chemical Industries, Ltd. Angiostatic agents
WO1992002240A2 (en) * 1990-07-27 1992-02-20 Repligen Corporation Novel methods and compositions for treatment of angiogenic diseases
US5328930A (en) 1993-03-01 1994-07-12 Emory University Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin
CN1072485C (zh) * 1995-03-27 2001-10-10 萨诺费合成实验室 夫马菌醇及其衍生物用于制备抗肠道感染药物的用途
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
CA2210600A1 (en) * 1996-07-17 1998-01-17 Takashi Houkan Inhibitor of tumor metastasis or recurrence
AU3968597A (en) * 1996-08-02 1998-02-25 Children's Medical Center Corporation Method of regulating the female reproductive system through angiogenesis inhibitors

Also Published As

Publication number Publication date
CN1072485C (zh) 2001-10-10
SK283883B6 (sk) 2004-04-06
IS2048B (is) 2005-09-15
SK130797A3 (en) 1998-03-04
UA41446C2 (uk) 2001-09-17
EA199700267A1 (ru) 1998-04-30
CA2216623C (en) 2005-05-31
KR100286920B1 (ko) 2001-04-16
MX9707150A (es) 1998-07-31
CA2216623A1 (en) 1996-10-03
OA10515A (fr) 2002-04-24
JP3260378B2 (ja) 2002-02-25
KR19980703271A (ko) 1998-10-15
AP646A (en) 1998-04-27
NO974466L (no) 1997-09-26
HUP9801220A2 (hu) 1999-09-28
EP0817626B1 (fr) 1998-10-28
PL322470A1 (en) 1998-02-02
EP0817626A2 (fr) 1998-01-14
PL183378B1 (pl) 2002-06-28
WO1996030010A2 (fr) 1996-10-03
DK0817626T3 (da) 1999-07-12
CZ286821B6 (en) 2000-07-12
NO315968B1 (no) 2003-11-24
DE69600879T2 (de) 1999-06-02
IS4557A (is) 1997-09-11
CZ304997A3 (en) 1997-12-17
HUP9801220A3 (en) 2001-10-29
FR06C0014I2 (en:Method) 2006-12-29
US5900431A (en) 1999-05-04
FR06C0014I1 (en:Method) 2006-11-17
AP9701092A0 (en) 1997-10-31
AU5278696A (en) 1996-10-16
HU224028B1 (hu) 2005-05-30
WO1996030010A3 (fr) 1996-11-28
ES2128846T3 (es) 1999-05-16
CN1179715A (zh) 1998-04-22
JPH11506421A (ja) 1999-06-08
EA000150B1 (ru) 1998-10-29
AU706161B2 (en) 1999-06-10
DE69600879D1 (de) 1998-12-03
NO974466D0 (no) 1997-09-26
NZ304906A (en) 1999-06-29
ATE172641T1 (de) 1998-11-15

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