TNSN96090A1 - Procede pour la purification optique de composes - Google Patents

Procede pour la purification optique de composes

Info

Publication number
TNSN96090A1
TNSN96090A1 TNPCT/SE1995/000817A TNSN96090A TNSN96090A1 TN SN96090 A1 TNSN96090 A1 TN SN96090A1 TN SN96090 A TNSN96090 A TN SN96090A TN SN96090 A1 TNSN96090 A1 TN SN96090A1
Authority
TN
Tunisia
Prior art keywords
compounds
optical purification
purification
optical
sulfoxides
Prior art date
Application number
TNPCT/SE1995/000817A
Other languages
English (en)
Inventor
Unge Sverker Von
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20397468&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TNSN96090(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Publication of TNSN96090A1 publication Critical patent/TNSN96090A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN PROCEDE POUR LA PURIFICATION OPTIQUE DES ENANTIOMERES SIMPLES D'UN CERTAIN NOMBRE DE DERIVES 2-SULFINYL-1H-BENZIMIDAZOLE ET D'AUTRES SULFOXYDES STRUCTURALEMENT LIES, A PARTIR DE LEURS PREPARATIONS RESPECTIVES AYANT SUBI UN ENRICHISSEMENT ENANTIOMERE
TNPCT/SE1995/000817A 1995-07-03 1996-07-02 Procede pour la purification optique de composes TNSN96090A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9500817 1995-07-03

Publications (1)

Publication Number Publication Date
TNSN96090A1 true TNSN96090A1 (fr) 2005-03-15

Family

ID=20397468

Family Applications (1)

Application Number Title Priority Date Filing Date
TNPCT/SE1995/000817A TNSN96090A1 (fr) 1995-07-03 1996-07-02 Procede pour la purification optique de composes

Country Status (37)

Country Link
US (1) US5929244A (fr)
EP (2) EP1498416A1 (fr)
JP (1) JP4195507B2 (fr)
KR (1) KR100451078B1 (fr)
CN (1) CN1098261C (fr)
AT (1) ATE418549T1 (fr)
AU (1) AU698638B2 (fr)
BR (1) BR9609450A (fr)
CA (1) CA2226184C (fr)
CZ (1) CZ295430B6 (fr)
DE (1) DE69637788D1 (fr)
DK (1) DK0836601T3 (fr)
DZ (1) DZ2057A1 (fr)
EE (1) EE03444B1 (fr)
ES (1) ES2318850T3 (fr)
HK (1) HK1010193A1 (fr)
HR (1) HRP960232A2 (fr)
HU (1) HUP9901717A3 (fr)
IL (1) IL122811A (fr)
IS (1) IS2666B (fr)
MA (1) MA23921A1 (fr)
MY (1) MY114018A (fr)
NO (1) NO313008B1 (fr)
NZ (1) NZ311842A (fr)
PL (1) PL186702B1 (fr)
PT (1) PT836601E (fr)
RS (1) RS49826B (fr)
RU (1) RU2144031C1 (fr)
SA (1) SA96170103B1 (fr)
SI (1) SI0836601T1 (fr)
SK (1) SK284780B6 (fr)
TN (1) TNSN96090A1 (fr)
TR (1) TR199701754T1 (fr)
TW (1) TW444010B (fr)
UA (1) UA49838C2 (fr)
WO (1) WO1997002261A1 (fr)
ZA (1) ZA965205B (fr)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
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HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6051570A (en) * 1997-05-30 2000-04-18 Dr. Reddy's Research Foundation Benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
JP2002501897A (ja) * 1998-01-30 2002-01-22 セプラコール， インク． Ｒ−ランソプラゾール組成物及び方法
SE9900274D0 (sv) 1999-01-28 1999-01-28 Astra Ab New compound
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
EP1191025B1 (fr) 1999-06-30 2005-06-22 Takeda Pharmaceutical Company Limited Cristaux de lansoprazole
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
ES2511774T3 (es) * 2000-05-15 2014-10-23 Takeda Pharmaceutical Company Limited Formas cristalinas de (R)-lansoprazol
CA2417311C (fr) 2000-08-04 2012-07-10 Takeda Chemical Industries, Ltd. Sels cristallins de metal alcalin et de lansoprazole et methode de production et utilisation connexes
TWI290922B (en) 2000-12-01 2007-12-11 Takeda Chemical Industries Ltd Production method of crystals
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0104295D0 (sv) * 2001-12-18 2001-12-18 Astrazeneca Ab New process
EP1469839A2 (fr) * 2002-01-25 2004-10-27 Santarus, Inc. Administration par voie muqueuse d'inhibiteurs de la pompe a protons
EP2596792A1 (fr) 2002-10-16 2013-05-29 Takeda Pharmaceutical Company Limited Préparations solides stables
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
DE10254167A1 (de) 2002-11-20 2004-06-09 Icon Genetics Ag Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen
SI1575941T1 (sl) 2002-12-06 2012-08-31 Nycomed Gmbh Postopek za pripravo (S)-pantoprazola
CA2507807C (fr) 2002-12-06 2013-10-22 Altana Pharma Ag Procede de preparation de composes actifs optiquement purs inhibiteurs de la pompe a protons
JP2006518751A (ja) * 2003-02-20 2006-08-17 サンタラス インコーポレイティッド 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物
RU2005129513A (ru) * 2003-02-28 2006-03-10 Рэнбакси Лабораториз Лимитед (In) Полиморфы s-омепразола
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
TWI337877B (en) * 2003-07-18 2011-03-01 Santarus Inc Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
FR2863609A1 (fr) * 2003-12-15 2005-06-17 Isochem Sa Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2570916C (fr) 2004-06-16 2013-06-11 Tap Pharmaceutical Products, Inc. Forme posologique d'ipp a doses multiples
EP1801110A1 (fr) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Sel d'arginine d'ésoméprazole
US7553857B2 (en) 2005-12-23 2009-06-30 Lek Pharmaceuticals D.D. S-omeprazole magnesium
US7786309B2 (en) * 2006-06-09 2010-08-31 Apotex Pharmachem Inc. Process for the preparation of esomeprazole and salts thereof
FR2909380B1 (fr) * 2006-12-04 2009-02-20 Sidem Pharma Sa Sa Conglomerats de sels de potassium de tenatoprazole
EP1947099A1 (fr) 2007-01-18 2008-07-23 LEK Pharmaceuticals D.D. Procédé pour l'élimination de solvant des sels d'oméprazole
BRPI0813191B1 (pt) * 2007-06-15 2021-09-08 Emcure Pharmaceuticals Limited Processo de sulfoxidação de compostos biologicamente ativos
CN101323609B (zh) * 2007-06-15 2013-05-01 成都福瑞生物工程有限公司 不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法
FR2920428B1 (fr) * 2007-08-29 2012-06-15 Univ Rouen Procede de dedoublement de sels de l'omeprazole
JP2011513202A (ja) 2008-03-10 2011-04-28 武田薬品工業株式会社 ベンズイミダゾール化合物の結晶
WO2010058409A2 (fr) 2008-11-18 2010-05-27 Hetero Research Foundation Purification optique d'esoméprazole
KR101001646B1 (ko) * 2008-12-12 2010-12-17 한미약품 주식회사 (ｒ)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체
WO2011004387A2 (fr) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Procédé de préparation de formes polymorphes du dexlansoprazole
WO2011058569A1 (fr) 2009-11-12 2011-05-19 Hetero Research Foundation Procédé de dédoublement de l'oméprazole
CA2788147A1 (fr) 2010-01-29 2011-08-04 Ranbaxy Laboratories Limited Procede pour la preparation de formes cristallines de dexlansoprazole
KR102091211B1 (ko) * 2014-07-30 2020-03-19 가부시키가이샤 아에타스 파루마 1,4-벤조티아제핀-1-옥사이드 유도체의 광학 이성질체, 및 그것을 사용한 의약 조성물
ES2615637T3 (es) * 2015-03-06 2017-06-07 F.I.S.- Fabbrica Italiana Sintetici S.P.A. Procedimiento mejorado para la purificación óptica del esomeprazol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU4640985A (en) * 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
DE69011645T2 (de) * 1989-11-29 1995-01-12 Toa Eiyo Ltd Cycloheptenopyridinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Antiulkusmitteln.
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
IS4232A (is) * 1993-12-06 1995-06-07 Astra Aktiebolag Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds

Also Published As

Publication number Publication date
KR19990028631A (ko) 1999-04-15
DE69637788D1 (de) 2009-02-05
RU2144031C1 (ru) 2000-01-10
EP0836601B1 (fr) 2008-12-24
CZ421197A3 (cs) 1998-06-17
EP1498416A1 (fr) 2005-01-19
EE03444B1 (et) 2001-06-15
SA96170103B1 (ar) 2006-07-30
KR100451078B1 (ko) 2004-11-16
SI0836601T1 (sl) 2009-04-30
BR9609450A (pt) 1999-03-02
DK0836601T3 (da) 2009-03-16
ZA965205B (en) 1997-01-03
IL122811A (en) 2000-11-21
RS49826B (sr) 2008-08-07
NO976030L (no) 1998-02-09
HUP9901717A3 (en) 2002-03-28
NO313008B1 (no) 2002-07-29
ATE418549T1 (de) 2009-01-15
WO1997002261A1 (fr) 1997-01-23
NO976030D0 (no) 1997-12-22
MX9800160A (es) 1998-03-31
EE9700368A (et) 1998-06-15
TW444010B (en) 2001-07-01
IL122811A0 (en) 1998-08-16
JPH11508590A (ja) 1999-07-27
AU6324096A (en) 1997-02-05
SK179397A3 (en) 1998-09-09
YU37696A (sh) 1999-03-04
MA23921A1 (fr) 1996-12-31
UA49838C2 (uk) 2002-10-15
CA2226184A1 (fr) 1997-01-23
PL324394A1 (en) 1998-05-25
CA2226184C (fr) 2008-08-05
CN1193971A (zh) 1998-09-23
HK1010193A1 (en) 1999-06-17
HUP9901717A2 (hu) 2000-04-28
SK284780B6 (sk) 2005-11-03
CZ295430B6 (cs) 2005-08-17
US5929244A (en) 1999-07-27
DZ2057A1 (fr) 2002-10-20
NZ311842A (en) 1998-12-23
IS4638A (is) 1997-12-22
TR199701754T1 (xx) 1998-04-21
MY114018A (en) 2002-07-31
CN1098261C (zh) 2003-01-08
ES2318850T3 (es) 2009-05-01
AU698638B2 (en) 1998-11-05
PL186702B1 (pl) 2004-02-27
PT836601E (pt) 2009-02-17
IS2666B (is) 2010-08-15
HRP960232A2 (en) 1998-02-28
JP4195507B2 (ja) 2008-12-10
EP0836601A1 (fr) 1998-04-22

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