BR9609450A - Processo para a purificação óptica de preparações enriquecidas enanciomericamente e composto - Google Patents
Processo para a purificação óptica de preparações enriquecidas enanciomericamente e compostoInfo
- Publication number
- BR9609450A BR9609450A BR9609450A BR9609450A BR9609450A BR 9609450 A BR9609450 A BR 9609450A BR 9609450 A BR9609450 A BR 9609450A BR 9609450 A BR9609450 A BR 9609450A BR 9609450 A BR9609450 A BR 9609450A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- optical purification
- enriched preparations
- enanciomerically
- enanciomerically enriched
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9500817 | 1995-07-03 | ||
PCT/SE1996/000841 WO1997002261A1 (en) | 1995-07-03 | 1996-06-26 | A process for the optical purification of enantiomerically enriched benzimidazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9609450A true BR9609450A (pt) | 1999-03-02 |
Family
ID=20397468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9609450A BR9609450A (pt) | 1995-07-03 | 1996-06-26 | Processo para a purificação óptica de preparações enriquecidas enanciomericamente e composto |
Country Status (37)
Country | Link |
---|---|
US (1) | US5929244A (pt) |
EP (2) | EP1498416A1 (pt) |
JP (1) | JP4195507B2 (pt) |
KR (1) | KR100451078B1 (pt) |
CN (1) | CN1098261C (pt) |
AT (1) | ATE418549T1 (pt) |
AU (1) | AU698638B2 (pt) |
BR (1) | BR9609450A (pt) |
CA (1) | CA2226184C (pt) |
CZ (1) | CZ295430B6 (pt) |
DE (1) | DE69637788D1 (pt) |
DK (1) | DK0836601T3 (pt) |
DZ (1) | DZ2057A1 (pt) |
EE (1) | EE03444B1 (pt) |
ES (1) | ES2318850T3 (pt) |
HK (1) | HK1010193A1 (pt) |
HR (1) | HRP960232A2 (pt) |
HU (1) | HUP9901717A3 (pt) |
IL (1) | IL122811A (pt) |
IS (1) | IS2666B (pt) |
MA (1) | MA23921A1 (pt) |
MY (1) | MY114018A (pt) |
NO (1) | NO313008B1 (pt) |
NZ (1) | NZ311842A (pt) |
PL (1) | PL186702B1 (pt) |
PT (1) | PT836601E (pt) |
RS (1) | RS49826B (pt) |
RU (1) | RU2144031C1 (pt) |
SA (1) | SA96170103B1 (pt) |
SI (1) | SI0836601T1 (pt) |
SK (1) | SK284780B6 (pt) |
TN (1) | TNSN96090A1 (pt) |
TR (1) | TR199701754T1 (pt) |
TW (1) | TW444010B (pt) |
UA (1) | UA49838C2 (pt) |
WO (1) | WO1997002261A1 (pt) |
ZA (1) | ZA965205B (pt) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
EP0983263A1 (en) * | 1997-05-30 | 2000-03-08 | Dr. Reddy's Research Foundation | Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them |
JP2002501897A (ja) * | 1998-01-30 | 2002-01-22 | セプラコール, インク. | R−ランソプラゾール組成物及び方法 |
SE9900274D0 (sv) | 1999-01-28 | 1999-01-28 | Astra Ab | New compound |
TWI289557B (en) | 1999-06-17 | 2007-11-11 | Takeda Chemical Industries Ltd | A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole |
DE60020967T2 (de) | 1999-06-30 | 2006-05-04 | Takeda Pharmaceutical Co. Ltd. | Kristalle von lansoprazole |
US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
DE60131649T2 (de) | 2000-05-15 | 2008-10-30 | Takeda Pharmaceutical Co. Ltd. | Verfahren zur herstellung eines kristalls |
CA2417311C (en) | 2000-08-04 | 2012-07-10 | Takeda Chemical Industries, Ltd. | Crystalline alkali metal salts of lansoprazole and their production and use |
KR20100002278A (ko) | 2000-12-01 | 2010-01-06 | 다케다 야쿠힌 고교 가부시키가이샤 | (r)- 또는 (s)-란소프라졸의 결정 |
KR100433735B1 (ko) * | 2001-06-27 | 2004-06-04 | 주식회사 씨트리 | 결정형 ⅰ을 갖는 란소프라졸의 제조방법 |
SE0104295D0 (sv) * | 2001-12-18 | 2001-12-18 | Astrazeneca Ab | New process |
US20040006111A1 (en) * | 2002-01-25 | 2004-01-08 | Kenneth Widder | Transmucosal delivery of proton pump inhibitors |
MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
US8697094B2 (en) | 2002-10-16 | 2014-04-15 | Takeda Pharmaceutical Company Limited | Stable solid preparations |
DE10254167A1 (de) | 2002-11-20 | 2004-06-09 | Icon Genetics Ag | Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen |
MXPA05005762A (es) | 2002-12-06 | 2005-08-16 | Altana Pharma Ag | Procedimiento para preparar compuestos activos opticamente puros. |
PL375695A1 (en) | 2002-12-06 | 2005-12-12 | Altana Pharma Ag | Process for preparing (s)-pantoprazole |
US20040248942A1 (en) * | 2003-02-20 | 2004-12-09 | Bonnie Hepburn | Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid |
CA2517714A1 (en) * | 2003-02-28 | 2004-09-10 | Ranbaxy Laboratories Limited | Polymorphs of s-omeprazole |
US20050031700A1 (en) * | 2003-07-18 | 2005-02-10 | Sanatarus, Inc. | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US7005732B2 (en) * | 2003-10-21 | 2006-02-28 | Honeywell International Inc. | Methods and systems for providing MEMS devices with a top cap and upper sense plate |
FR2863609A1 (fr) * | 2003-12-15 | 2005-06-17 | Isochem Sa | Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides |
SE0400410D0 (sv) * | 2004-02-20 | 2004-02-20 | Astrazeneca Ab | New compounds |
US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
EP1768668A2 (en) | 2004-06-16 | 2007-04-04 | Tap Pharmaceutical Products, Inc. | Multiple ppi dosage form |
EP1801110A1 (en) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Esomeprazole arginine salt |
US7553857B2 (en) | 2005-12-23 | 2009-06-30 | Lek Pharmaceuticals D.D. | S-omeprazole magnesium |
US7786309B2 (en) * | 2006-06-09 | 2010-08-31 | Apotex Pharmachem Inc. | Process for the preparation of esomeprazole and salts thereof |
FR2909380B1 (fr) * | 2006-12-04 | 2009-02-20 | Sidem Pharma Sa Sa | Conglomerats de sels de potassium de tenatoprazole |
EP1947099A1 (en) | 2007-01-18 | 2008-07-23 | LEK Pharmaceuticals D.D. | Process for solvent removal from omeprazole salts |
CN101323609B (zh) * | 2007-06-15 | 2013-05-01 | 成都福瑞生物工程有限公司 | 不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法 |
KR101432866B1 (ko) * | 2007-06-15 | 2014-08-26 | 엠큐어 파마슈티컬즈 리미티드 | 생활성 화합물의 설폭사이드화 방법 |
FR2920428B1 (fr) * | 2007-08-29 | 2012-06-15 | Univ Rouen | Procede de dedoublement de sels de l'omeprazole |
PE20091680A1 (es) | 2008-03-10 | 2009-11-16 | Takeda Pharmaceutical | Cristal de compuestos de bencimidazol |
WO2010058409A2 (en) | 2008-11-18 | 2010-05-27 | Hetero Research Foundation | Optical purification of esomeprazole |
KR101001646B1 (ko) * | 2008-12-12 | 2010-12-17 | 한미약품 주식회사 | (r)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체 |
WO2011004387A2 (en) | 2009-06-18 | 2011-01-13 | Matrix Laboratories Ltd | Process for the preparation of dexlansoprazole polymorphic forms |
US8748619B2 (en) | 2009-11-12 | 2014-06-10 | Hetero Research Foundation | Process for the resolution of omeprazole |
AU2011210328A1 (en) | 2010-01-29 | 2012-08-16 | Ranbaxy Laboratories Limited | Process for the preparation of crystalline forms of dexlansoprazole |
US10071996B2 (en) | 2014-07-30 | 2018-09-11 | Aetas Pharma Co., Ltd. | Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same |
EP3064495B1 (en) | 2015-03-06 | 2016-12-14 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Improved process for the preparation of optically pure esomeprazole |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
AU4640985A (en) * | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
ES2057338T3 (es) * | 1989-11-29 | 1994-10-16 | Toa Eiyo Ltd | Derivados de cicloheptenopiridina, procedimiento para su preparacion y agentes antiulcerosos que los contienen. |
DE4035455A1 (de) * | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
IS4232A (is) * | 1993-12-06 | 1995-06-07 | Astra Aktiebolag | Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun |
HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
-
1996
- 1996-05-21 HR HRPCT/SE95/00817A patent/HRP960232A2/hr not_active Application Discontinuation
- 1996-06-19 ZA ZA965205A patent/ZA965205B/xx unknown
- 1996-06-19 SA SA96170103A patent/SA96170103B1/ar unknown
- 1996-06-19 RS YUP-376/96A patent/RS49826B/sr unknown
- 1996-06-22 TW TW085107517A patent/TW444010B/zh not_active IP Right Cessation
- 1996-06-26 CN CN96196465A patent/CN1098261C/zh not_active Expired - Lifetime
- 1996-06-26 TR TR97/01754T patent/TR199701754T1/xx unknown
- 1996-06-26 IL IL12281196A patent/IL122811A/xx not_active IP Right Cessation
- 1996-06-26 BR BR9609450A patent/BR9609450A/pt not_active Application Discontinuation
- 1996-06-26 RU RU98101727A patent/RU2144031C1/ru not_active IP Right Cessation
- 1996-06-26 CZ CZ19974211A patent/CZ295430B6/cs not_active IP Right Cessation
- 1996-06-26 JP JP50506397A patent/JP4195507B2/ja not_active Expired - Lifetime
- 1996-06-26 ES ES96922339T patent/ES2318850T3/es not_active Expired - Lifetime
- 1996-06-26 HU HU9901717A patent/HUP9901717A3/hu not_active Application Discontinuation
- 1996-06-26 DE DE69637788T patent/DE69637788D1/de not_active Expired - Lifetime
- 1996-06-26 SI SI9630766T patent/SI0836601T1/sl unknown
- 1996-06-26 EP EP04024339A patent/EP1498416A1/en not_active Withdrawn
- 1996-06-26 AT AT96922339T patent/ATE418549T1/de active
- 1996-06-26 UA UA97126300A patent/UA49838C2/uk unknown
- 1996-06-26 WO PCT/SE1996/000841 patent/WO1997002261A1/en active IP Right Grant
- 1996-06-26 US US08/676,215 patent/US5929244A/en not_active Expired - Lifetime
- 1996-06-26 CA CA002226184A patent/CA2226184C/en not_active Expired - Lifetime
- 1996-06-26 PL PL96324394A patent/PL186702B1/pl not_active IP Right Cessation
- 1996-06-26 DZ DZ960101A patent/DZ2057A1/fr active
- 1996-06-26 EP EP96922339A patent/EP0836601B1/en not_active Expired - Lifetime
- 1996-06-26 KR KR1019970709953A patent/KR100451078B1/ko not_active IP Right Cessation
- 1996-06-26 NZ NZ311842A patent/NZ311842A/xx not_active IP Right Cessation
- 1996-06-26 EE EE9700368A patent/EE03444B1/xx not_active IP Right Cessation
- 1996-06-26 SK SK1793-97A patent/SK284780B6/sk not_active IP Right Cessation
- 1996-06-26 DK DK96922339T patent/DK0836601T3/da active
- 1996-06-26 PT PT96922339T patent/PT836601E/pt unknown
- 1996-06-26 AU AU63240/96A patent/AU698638B2/en not_active Expired
- 1996-06-28 MA MA24295A patent/MA23921A1/fr unknown
- 1996-07-02 TN TNPCT/SE1995/000817A patent/TNSN96090A1/fr unknown
- 1996-07-03 MY MYPI96002734A patent/MY114018A/en unknown
-
1997
- 1997-01-21 IS IS4638A patent/IS2666B/is unknown
- 1997-12-22 NO NO19976030A patent/NO313008B1/no not_active IP Right Cessation
-
1998
- 1998-09-26 HK HK98110996.6A patent/HK1010193A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Decision: refusal |