SI0836601T1 - Postopek za optično čiščenje enantiomerno obogatenih benzimidazolnih derivatov - Google Patents

Postopek za optično čiščenje enantiomerno obogatenih benzimidazolnih derivatov

Info

Publication number
SI0836601T1
SI0836601T1 SI9630766T SI9630766T SI0836601T1 SI 0836601 T1 SI0836601 T1 SI 0836601T1 SI 9630766 T SI9630766 T SI 9630766T SI 9630766 T SI9630766 T SI 9630766T SI 0836601 T1 SI0836601 T1 SI 0836601T1
Authority
SI
Slovenia
Prior art keywords
enantiomerically enriched
benzimidazole derivatives
optical purification
enriched benzimidazole
purification
Prior art date
Application number
SI9630766T
Other languages
English (en)
Inventor
Unge Sverker Von
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20397468&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI0836601(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SI0836601T1 publication Critical patent/SI0836601T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9630766T 1995-07-03 1996-06-26 Postopek za optično čiščenje enantiomerno obogatenih benzimidazolnih derivatov SI0836601T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9500817 1995-07-03
PCT/SE1996/000841 WO1997002261A1 (en) 1995-07-03 1996-06-26 A process for the optical purification of enantiomerically enriched benzimidazole derivatives
EP96922339A EP0836601B1 (en) 1995-07-03 1996-06-26 A process for the optical purification of enantiomerically enriched benzimidazole derivatives

Publications (1)

Publication Number Publication Date
SI0836601T1 true SI0836601T1 (sl) 2009-04-30

Family

ID=20397468

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630766T SI0836601T1 (sl) 1995-07-03 1996-06-26 Postopek za optično čiščenje enantiomerno obogatenih benzimidazolnih derivatov

Country Status (37)

Country Link
US (1) US5929244A (sl)
EP (2) EP1498416A1 (sl)
JP (1) JP4195507B2 (sl)
KR (1) KR100451078B1 (sl)
CN (1) CN1098261C (sl)
AT (1) ATE418549T1 (sl)
AU (1) AU698638B2 (sl)
BR (1) BR9609450A (sl)
CA (1) CA2226184C (sl)
CZ (1) CZ295430B6 (sl)
DE (1) DE69637788D1 (sl)
DK (1) DK0836601T3 (sl)
DZ (1) DZ2057A1 (sl)
EE (1) EE03444B1 (sl)
ES (1) ES2318850T3 (sl)
HK (1) HK1010193A1 (sl)
HR (1) HRP960232A2 (sl)
HU (1) HUP9901717A3 (sl)
IL (1) IL122811A (sl)
IS (1) IS2666B (sl)
MA (1) MA23921A1 (sl)
MY (1) MY114018A (sl)
NO (1) NO313008B1 (sl)
NZ (1) NZ311842A (sl)
PL (1) PL186702B1 (sl)
PT (1) PT836601E (sl)
RS (1) RS49826B (sl)
RU (1) RU2144031C1 (sl)
SA (1) SA96170103B1 (sl)
SI (1) SI0836601T1 (sl)
SK (1) SK284780B6 (sl)
TN (1) TNSN96090A1 (sl)
TR (1) TR199701754T1 (sl)
TW (1) TW444010B (sl)
UA (1) UA49838C2 (sl)
WO (1) WO1997002261A1 (sl)
ZA (1) ZA965205B (sl)

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US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
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US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
ES2511774T3 (es) * 2000-05-15 2014-10-23 Takeda Pharmaceutical Company Limited Formas cristalinas de (R)-lansoprazol
CA2417311C (en) 2000-08-04 2012-07-10 Takeda Chemical Industries, Ltd. Crystalline alkali metal salts of lansoprazole and their production and use
TWI290922B (en) 2000-12-01 2007-12-11 Takeda Chemical Industries Ltd Production method of crystals
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0104295D0 (sv) * 2001-12-18 2001-12-18 Astrazeneca Ab New process
EP1469839A2 (en) * 2002-01-25 2004-10-27 Santarus, Inc. Transmucosal delivery of proton pump inhibitors
EP2596792A1 (en) 2002-10-16 2013-05-29 Takeda Pharmaceutical Company Limited Stable solid preparations
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
DE10254167A1 (de) 2002-11-20 2004-06-09 Icon Genetics Ag Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen
SI1575941T1 (sl) 2002-12-06 2012-08-31 Nycomed Gmbh Postopek za pripravo (S)-pantoprazola
CA2507807C (en) 2002-12-06 2013-10-22 Altana Pharma Ag Process for preparing optically pure proton pump inhibitors
JP2006518751A (ja) * 2003-02-20 2006-08-17 サンタラス インコーポレイティッド 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物
RU2005129513A (ru) * 2003-02-28 2006-03-10 Рэнбакси Лабораториз Лимитед (In) Полиморфы s-омепразола
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
TWI337877B (en) * 2003-07-18 2011-03-01 Santarus Inc Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
FR2863609A1 (fr) * 2003-12-15 2005-06-17 Isochem Sa Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2570916C (en) 2004-06-16 2013-06-11 Tap Pharmaceutical Products, Inc. Pulsed release dosage form of a ppi
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
US7553857B2 (en) 2005-12-23 2009-06-30 Lek Pharmaceuticals D.D. S-omeprazole magnesium
US7786309B2 (en) * 2006-06-09 2010-08-31 Apotex Pharmachem Inc. Process for the preparation of esomeprazole and salts thereof
FR2909380B1 (fr) * 2006-12-04 2009-02-20 Sidem Pharma Sa Sa Conglomerats de sels de potassium de tenatoprazole
EP1947099A1 (en) 2007-01-18 2008-07-23 LEK Pharmaceuticals D.D. Process for solvent removal from omeprazole salts
BRPI0813191B1 (pt) * 2007-06-15 2021-09-08 Emcure Pharmaceuticals Limited Processo de sulfoxidação de compostos biologicamente ativos
CN101323609B (zh) * 2007-06-15 2013-05-01 成都福瑞生物工程有限公司 不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法
FR2920428B1 (fr) * 2007-08-29 2012-06-15 Univ Rouen Procede de dedoublement de sels de l'omeprazole
JP2011513202A (ja) 2008-03-10 2011-04-28 武田薬品工業株式会社 ベンズイミダゾール化合物の結晶
WO2010058409A2 (en) 2008-11-18 2010-05-27 Hetero Research Foundation Optical purification of esomeprazole
KR101001646B1 (ko) * 2008-12-12 2010-12-17 한미약품 주식회사 (ｒ)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체
WO2011004387A2 (en) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Process for the preparation of dexlansoprazole polymorphic forms
WO2011058569A1 (en) 2009-11-12 2011-05-19 Hetero Research Foundation Process for the resolution of omeprazole
CA2788147A1 (en) 2010-01-29 2011-08-04 Ranbaxy Laboratories Limited Process for the preparation of crystalline forms of dexlansoprazole
KR102091211B1 (ko) * 2014-07-30 2020-03-19 가부시키가이샤 아에타스 파루마 1,4-벤조티아제핀-1-옥사이드 유도체의 광학 이성질체, 및 그것을 사용한 의약 조성물
ES2615637T3 (es) * 2015-03-06 2017-06-07 F.I.S.- Fabbrica Italiana Sintetici S.P.A. Procedimiento mejorado para la purificación óptica del esomeprazol

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JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU4640985A (en) * 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
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HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds

Also Published As

Publication number Publication date
KR19990028631A (ko) 1999-04-15
DE69637788D1 (de) 2009-02-05
RU2144031C1 (ru) 2000-01-10
EP0836601B1 (en) 2008-12-24
CZ421197A3 (cs) 1998-06-17
EP1498416A1 (en) 2005-01-19
EE03444B1 (et) 2001-06-15
SA96170103B1 (ar) 2006-07-30
KR100451078B1 (ko) 2004-11-16
BR9609450A (pt) 1999-03-02
DK0836601T3 (da) 2009-03-16
ZA965205B (en) 1997-01-03
IL122811A (en) 2000-11-21
RS49826B (sr) 2008-08-07
NO976030L (no) 1998-02-09
HUP9901717A3 (en) 2002-03-28
NO313008B1 (no) 2002-07-29
ATE418549T1 (de) 2009-01-15
WO1997002261A1 (en) 1997-01-23
NO976030D0 (no) 1997-12-22
MX9800160A (es) 1998-03-31
EE9700368A (et) 1998-06-15
TW444010B (en) 2001-07-01
IL122811A0 (en) 1998-08-16
JPH11508590A (ja) 1999-07-27
AU6324096A (en) 1997-02-05
SK179397A3 (en) 1998-09-09
YU37696A (sh) 1999-03-04
MA23921A1 (fr) 1996-12-31
UA49838C2 (uk) 2002-10-15
CA2226184A1 (en) 1997-01-23
PL324394A1 (en) 1998-05-25
CA2226184C (en) 2008-08-05
CN1193971A (zh) 1998-09-23
HK1010193A1 (en) 1999-06-17
HUP9901717A2 (hu) 2000-04-28
SK284780B6 (sk) 2005-11-03
CZ295430B6 (cs) 2005-08-17
US5929244A (en) 1999-07-27
DZ2057A1 (fr) 2002-10-20
NZ311842A (en) 1998-12-23
IS4638A (is) 1997-12-22
TNSN96090A1 (fr) 2005-03-15
TR199701754T1 (xx) 1998-04-21
MY114018A (en) 2002-07-31
CN1098261C (zh) 2003-01-08
ES2318850T3 (es) 2009-05-01
AU698638B2 (en) 1998-11-05
PL186702B1 (pl) 2004-02-27
PT836601E (pt) 2009-02-17
IS2666B (is) 2010-08-15
HRP960232A2 (en) 1998-02-28
JP4195507B2 (ja) 2008-12-10
EP0836601A1 (en) 1998-04-22

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