NO976030D0 - Fremgangsmåte for optisk rensing av enantiomerisk anrikede benzimidazolderivater - Google Patents
Fremgangsmåte for optisk rensing av enantiomerisk anrikede benzimidazolderivaterInfo
- Publication number
- NO976030D0 NO976030D0 NO976030A NO976030A NO976030D0 NO 976030 D0 NO976030 D0 NO 976030D0 NO 976030 A NO976030 A NO 976030A NO 976030 A NO976030 A NO 976030A NO 976030 D0 NO976030 D0 NO 976030D0
- Authority
- NO
- Norway
- Prior art keywords
- enantiomerically enriched
- benzimidazole derivatives
- optical purification
- enriched benzimidazole
- purification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49193995A | 1995-07-03 | 1995-07-03 | |
SE9500817 | 1995-07-03 | ||
PCT/SE1996/000841 WO1997002261A1 (en) | 1995-07-03 | 1996-06-26 | A process for the optical purification of enantiomerically enriched benzimidazole derivatives |
Publications (3)
Publication Number | Publication Date |
---|---|
NO976030D0 true NO976030D0 (no) | 1997-12-22 |
NO976030L NO976030L (no) | 1998-02-09 |
NO313008B1 NO313008B1 (no) | 2002-07-29 |
Family
ID=20397468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19976030A NO313008B1 (no) | 1995-07-03 | 1997-12-22 | Fremgangsmåte for optisk rensing av enantiomerisk anrikede benzimidazolderivater |
Country Status (37)
Country | Link |
---|---|
US (1) | US5929244A (no) |
EP (2) | EP0836601B1 (no) |
JP (1) | JP4195507B2 (no) |
KR (1) | KR100451078B1 (no) |
CN (1) | CN1098261C (no) |
AT (1) | ATE418549T1 (no) |
AU (1) | AU698638B2 (no) |
BR (1) | BR9609450A (no) |
CA (1) | CA2226184C (no) |
CZ (1) | CZ295430B6 (no) |
DE (1) | DE69637788D1 (no) |
DK (1) | DK0836601T3 (no) |
DZ (1) | DZ2057A1 (no) |
EE (1) | EE03444B1 (no) |
ES (1) | ES2318850T3 (no) |
HK (1) | HK1010193A1 (no) |
HR (1) | HRP960232A2 (no) |
HU (1) | HUP9901717A3 (no) |
IL (1) | IL122811A (no) |
IS (1) | IS2666B (no) |
MA (1) | MA23921A1 (no) |
MY (1) | MY114018A (no) |
NO (1) | NO313008B1 (no) |
NZ (1) | NZ311842A (no) |
PL (1) | PL186702B1 (no) |
PT (1) | PT836601E (no) |
RS (1) | RS49826B (no) |
RU (1) | RU2144031C1 (no) |
SA (1) | SA96170103B1 (no) |
SI (1) | SI0836601T1 (no) |
SK (1) | SK284780B6 (no) |
TN (1) | TNSN96090A1 (no) |
TR (1) | TR199701754T1 (no) |
TW (1) | TW444010B (no) |
UA (1) | UA49838C2 (no) |
WO (1) | WO1997002261A1 (no) |
ZA (1) | ZA965205B (no) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
WO1998054172A1 (en) * | 1997-05-30 | 1998-12-03 | Dr. Reddy's Research Foundation | Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them |
AU742620B2 (en) * | 1998-01-30 | 2002-01-10 | Sepracor, Inc. | R-lansoprazole compositions and methods |
SE9900274D0 (sv) | 1999-01-28 | 1999-01-28 | Astra Ab | New compound |
TWI289557B (en) | 1999-06-17 | 2007-11-11 | Takeda Chemical Industries Ltd | A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole |
ES2240113T3 (es) | 1999-06-30 | 2005-10-16 | Takeda Pharmaceutical Company Limited | Cristales de lansoprazol. |
US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
EP1897877B1 (en) | 2000-05-15 | 2014-09-24 | Takeda Pharmaceutical Company Limited | Crystalline forms of (R)-lanzoprazole |
EP1306375B1 (en) | 2000-08-04 | 2006-10-11 | Takeda Pharmaceutical Company Limited | Salts of benzimidazole compound and application thereof |
PL399787A1 (pl) * | 2000-12-01 | 2012-11-05 | Takeda Pharmaceutical Company Ltd. | Krysztaly (R)- lub (S)-2-[[[3-metylo-4-(2,2,2-trifluoroetoksy)-2-pirydynylo]metylo]sulfinylo]-1H-benzimidazolu, kompozycja farmaceutyczna zawierajaca te krysztaly i ich zastosowanie |
KR100433735B1 (ko) * | 2001-06-27 | 2004-06-04 | 주식회사 씨트리 | 결정형 ⅰ을 갖는 란소프라졸의 제조방법 |
SE0104295D0 (sv) * | 2001-12-18 | 2001-12-18 | Astrazeneca Ab | New process |
US20040006111A1 (en) * | 2002-01-25 | 2004-01-08 | Kenneth Widder | Transmucosal delivery of proton pump inhibitors |
MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
CA2502219C (en) | 2002-10-16 | 2012-05-29 | Takeda Pharmaceutical Company Limited | A process for producing an amorphous isomer of lansoprazole |
DE10254167A1 (de) | 2002-11-20 | 2004-06-09 | Icon Genetics Ag | Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen |
MXPA05005762A (es) | 2002-12-06 | 2005-08-16 | Altana Pharma Ag | Procedimiento para preparar compuestos activos opticamente puros. |
ES2383679T3 (es) | 2002-12-06 | 2012-06-25 | Nycomed Gmbh | Procedimiento para la preparación de (S)-pantoprazol |
JP2006518751A (ja) * | 2003-02-20 | 2006-08-17 | サンタラス インコーポレイティッド | 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物 |
US20060247277A1 (en) * | 2003-02-28 | 2006-11-02 | Yatendra Kumar | Polymorphs of s-omeprazole |
MXPA06000524A (es) * | 2003-07-18 | 2006-08-11 | Santarus Inc | Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido. |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US7005732B2 (en) * | 2003-10-21 | 2006-02-28 | Honeywell International Inc. | Methods and systems for providing MEMS devices with a top cap and upper sense plate |
FR2863609A1 (fr) * | 2003-12-15 | 2005-06-17 | Isochem Sa | Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides |
SE0400410D0 (sv) * | 2004-02-20 | 2004-02-20 | Astrazeneca Ab | New compounds |
US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8461187B2 (en) | 2004-06-16 | 2013-06-11 | Takeda Pharmaceuticals U.S.A., Inc. | Multiple PPI dosage form |
EP1801110A1 (en) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Esomeprazole arginine salt |
US7553857B2 (en) | 2005-12-23 | 2009-06-30 | Lek Pharmaceuticals D.D. | S-omeprazole magnesium |
US7786309B2 (en) * | 2006-06-09 | 2010-08-31 | Apotex Pharmachem Inc. | Process for the preparation of esomeprazole and salts thereof |
FR2909380B1 (fr) * | 2006-12-04 | 2009-02-20 | Sidem Pharma Sa Sa | Conglomerats de sels de potassium de tenatoprazole |
EP1947099A1 (en) | 2007-01-18 | 2008-07-23 | LEK Pharmaceuticals D.D. | Process for solvent removal from omeprazole salts |
CN101323609B (zh) * | 2007-06-15 | 2013-05-01 | 成都福瑞生物工程有限公司 | 不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法 |
BRPI0813191B1 (pt) * | 2007-06-15 | 2021-09-08 | Emcure Pharmaceuticals Limited | Processo de sulfoxidação de compostos biologicamente ativos |
FR2920428B1 (fr) * | 2007-08-29 | 2012-06-15 | Univ Rouen | Procede de dedoublement de sels de l'omeprazole |
UA103189C2 (ru) | 2008-03-10 | 2013-09-25 | Такеда Фармасьютикал Компани Лимитед | Кристаллическая форма бензимидазольного соединения |
WO2010058409A2 (en) | 2008-11-18 | 2010-05-27 | Hetero Research Foundation | Optical purification of esomeprazole |
KR101001646B1 (ko) * | 2008-12-12 | 2010-12-17 | 한미약품 주식회사 | (r)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체 |
WO2011004387A2 (en) | 2009-06-18 | 2011-01-13 | Matrix Laboratories Ltd | Process for the preparation of dexlansoprazole polymorphic forms |
EP2499125B1 (en) | 2009-11-12 | 2016-01-27 | Hetero Research Foundation | Process for the resolution of omeprazole |
WO2011092665A1 (en) | 2010-01-29 | 2011-08-04 | Ranbaxy Laboratories Limited | Process for the preparation of crystalline forms of dexlansoprazole |
CA2956699C (en) | 2014-07-30 | 2020-09-29 | Aetas Pharma Co., Ltd. | Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same |
EP3064495B1 (en) | 2015-03-06 | 2016-12-14 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Improved process for the preparation of optically pure esomeprazole |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
AU4640985A (en) * | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
EP0434999B1 (en) * | 1989-11-29 | 1994-08-17 | Toa Eiyo Ltd. | Cycloheptenopyridine derivatives, process for preparation thereof and antiulcer agents containing the same |
DE4035455A1 (de) * | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
IS4232A (is) * | 1993-12-06 | 1995-06-07 | Astra Aktiebolag | Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun |
HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
-
1996
- 1996-05-21 HR HRPCT/SE95/00817A patent/HRP960232A2/hr not_active Application Discontinuation
- 1996-06-19 SA SA96170103A patent/SA96170103B1/ar unknown
- 1996-06-19 RS YUP-376/96A patent/RS49826B/sr unknown
- 1996-06-19 ZA ZA965205A patent/ZA965205B/xx unknown
- 1996-06-22 TW TW085107517A patent/TW444010B/zh not_active IP Right Cessation
- 1996-06-26 JP JP50506397A patent/JP4195507B2/ja not_active Expired - Lifetime
- 1996-06-26 EP EP96922339A patent/EP0836601B1/en not_active Expired - Lifetime
- 1996-06-26 AU AU63240/96A patent/AU698638B2/en not_active Expired
- 1996-06-26 HU HU9901717A patent/HUP9901717A3/hu not_active Application Discontinuation
- 1996-06-26 TR TR97/01754T patent/TR199701754T1/xx unknown
- 1996-06-26 ES ES96922339T patent/ES2318850T3/es not_active Expired - Lifetime
- 1996-06-26 KR KR1019970709953A patent/KR100451078B1/ko not_active IP Right Cessation
- 1996-06-26 DK DK96922339T patent/DK0836601T3/da active
- 1996-06-26 NZ NZ311842A patent/NZ311842A/xx not_active IP Right Cessation
- 1996-06-26 RU RU98101727A patent/RU2144031C1/ru not_active IP Right Cessation
- 1996-06-26 US US08/676,215 patent/US5929244A/en not_active Expired - Lifetime
- 1996-06-26 CA CA002226184A patent/CA2226184C/en not_active Expired - Lifetime
- 1996-06-26 IL IL12281196A patent/IL122811A/xx not_active IP Right Cessation
- 1996-06-26 DE DE69637788T patent/DE69637788D1/de not_active Expired - Lifetime
- 1996-06-26 SI SI9630766T patent/SI0836601T1/sl unknown
- 1996-06-26 BR BR9609450A patent/BR9609450A/pt not_active Application Discontinuation
- 1996-06-26 AT AT96922339T patent/ATE418549T1/de active
- 1996-06-26 UA UA97126300A patent/UA49838C2/uk unknown
- 1996-06-26 CZ CZ19974211A patent/CZ295430B6/cs not_active IP Right Cessation
- 1996-06-26 WO PCT/SE1996/000841 patent/WO1997002261A1/en active IP Right Grant
- 1996-06-26 DZ DZ960101A patent/DZ2057A1/fr active
- 1996-06-26 PT PT96922339T patent/PT836601E/pt unknown
- 1996-06-26 CN CN96196465A patent/CN1098261C/zh not_active Expired - Lifetime
- 1996-06-26 PL PL96324394A patent/PL186702B1/pl not_active IP Right Cessation
- 1996-06-26 EP EP04024339A patent/EP1498416A1/en not_active Withdrawn
- 1996-06-26 SK SK1793-97A patent/SK284780B6/sk not_active IP Right Cessation
- 1996-06-26 EE EE9700368A patent/EE03444B1/xx not_active IP Right Cessation
- 1996-06-28 MA MA24295A patent/MA23921A1/fr unknown
- 1996-07-02 TN TNPCT/SE1995/000817A patent/TNSN96090A1/fr unknown
- 1996-07-03 MY MYPI96002734A patent/MY114018A/en unknown
-
1997
- 1997-01-21 IS IS4638A patent/IS2666B/is unknown
- 1997-12-22 NO NO19976030A patent/NO313008B1/no not_active IP Right Cessation
-
1998
- 1998-09-26 HK HK98110996.6A patent/HK1010193A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
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MM1K | Lapsed by not paying the annual fees |