ZA965205B - Process for optical purification of compounds - Google Patents

Process for optical purification of compounds

Info

Publication number
ZA965205B
ZA965205B ZA965205A ZA965205A ZA965205B ZA 965205 B ZA965205 B ZA 965205B ZA 965205 A ZA965205 A ZA 965205A ZA 965205 A ZA965205 A ZA 965205A ZA 965205 B ZA965205 B ZA 965205B
Authority
ZA
South Africa
Prior art keywords
compounds
optical purification
purification
optical
sulphinyl
Prior art date
Application number
ZA965205A
Other languages
English (en)
Inventor
Sverker Von Unge
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20397468&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA965205(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA965205B publication Critical patent/ZA965205B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA965205A 1995-07-03 1996-06-19 Process for optical purification of compounds ZA965205B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9500817 1995-07-03

Publications (1)

Publication Number Publication Date
ZA965205B true ZA965205B (en) 1997-01-03

Family

ID=20397468

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA965205A ZA965205B (en) 1995-07-03 1996-06-19 Process for optical purification of compounds

Country Status (37)

Country Link
US (1) US5929244A (fr)
EP (2) EP1498416A1 (fr)
JP (1) JP4195507B2 (fr)
KR (1) KR100451078B1 (fr)
CN (1) CN1098261C (fr)
AT (1) ATE418549T1 (fr)
AU (1) AU698638B2 (fr)
BR (1) BR9609450A (fr)
CA (1) CA2226184C (fr)
CZ (1) CZ295430B6 (fr)
DE (1) DE69637788D1 (fr)
DK (1) DK0836601T3 (fr)
DZ (1) DZ2057A1 (fr)
EE (1) EE03444B1 (fr)
ES (1) ES2318850T3 (fr)
HK (1) HK1010193A1 (fr)
HR (1) HRP960232A2 (fr)
HU (1) HUP9901717A3 (fr)
IL (1) IL122811A (fr)
IS (1) IS2666B (fr)
MA (1) MA23921A1 (fr)
MY (1) MY114018A (fr)
NO (1) NO313008B1 (fr)
NZ (1) NZ311842A (fr)
PL (1) PL186702B1 (fr)
PT (1) PT836601E (fr)
RS (1) RS49826B (fr)
RU (1) RU2144031C1 (fr)
SA (1) SA96170103B1 (fr)
SI (1) SI0836601T1 (fr)
SK (1) SK284780B6 (fr)
TN (1) TNSN96090A1 (fr)
TR (1) TR199701754T1 (fr)
TW (1) TW444010B (fr)
UA (1) UA49838C2 (fr)
WO (1) WO1997002261A1 (fr)
ZA (1) ZA965205B (fr)

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HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
WO1998054172A1 (fr) * 1997-05-30 1998-12-03 Dr. Reddy's Research Foundation Nouveaux benzimidazoles utilises comme agents antiulcereux, leur procede de preparation et compositions pharmaceutiques les contenant
EP1056456A4 (fr) * 1998-01-30 2006-10-25 Sepracor Inc Compositions et procedes d'utilisation du r-lansoprazole
SE9900274D0 (sv) 1999-01-28 1999-01-28 Astra Ab New compound
TWI289557B (en) 1999-06-17 2007-11-11 Takeda Chemical Industries Ltd A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
WO2001002389A1 (fr) * 1999-06-30 2001-01-11 Takeda Chemical Industries, Ltd. Cristaux de composes benzimidazole
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
KR101035534B1 (ko) 2000-05-15 2011-05-23 다케다 야쿠힌 고교 가부시키가이샤 결정의 제조방법
CA2417311C (fr) 2000-08-04 2012-07-10 Takeda Chemical Industries, Ltd. Sels cristallins de metal alcalin et de lansoprazole et methode de production et utilisation connexes
KR100887912B1 (ko) 2000-12-01 2009-03-12 다케다 야쿠힌 고교 가부시키가이샤 (ｒ)- 또는 (ｓ)-란소프라졸의 결정화 방법
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0104295D0 (sv) * 2001-12-18 2001-12-18 Astrazeneca Ab New process
CA2472103A1 (fr) * 2002-01-25 2003-08-07 Santarus, Inc. Administration par voie muqueuse d'inhibiteurs de la pompe a protons
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US8697094B2 (en) 2002-10-16 2014-04-15 Takeda Pharmaceutical Company Limited Stable solid preparations
DE10254167A1 (de) 2002-11-20 2004-06-09 Icon Genetics Ag Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen
BRPI0310118B1 (pt) 2002-12-06 2015-10-20 Altana Pharma Ag processo para a preparação de inibidores de bomba de próton (ppi) opticamente puro possuindo uma estrutura de sulfinila
DK1575941T3 (da) 2002-12-06 2012-07-09 Nycomed Gmbh Fremgangsmåde til fremstilling af (S)-pantoprazol
EP1603537A4 (fr) * 2003-02-20 2009-11-04 Santarus Inc Liberation immediate d'un complexe antacide d'omeprazole presentant une nouvelle formulation pour une elimination rapide et prolongee d'acide gastrique
EP1606279A1 (fr) * 2003-02-28 2005-12-21 Ranbaxy Laboratories, Ltd. Polymorphes de s-omeprazole
AU2004257864A1 (en) * 2003-07-18 2005-01-27 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
FR2863609A1 (fr) * 2003-12-15 2005-06-17 Isochem Sa Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
JP5563735B2 (ja) 2004-06-16 2014-07-30 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド Ｐｐｉ多回剤形
EP1801110A1 (fr) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Sel d'arginine d'ésoméprazole
US7553857B2 (en) 2005-12-23 2009-06-30 Lek Pharmaceuticals D.D. S-omeprazole magnesium
US7786309B2 (en) * 2006-06-09 2010-08-31 Apotex Pharmachem Inc. Process for the preparation of esomeprazole and salts thereof
FR2909380B1 (fr) * 2006-12-04 2009-02-20 Sidem Pharma Sa Sa Conglomerats de sels de potassium de tenatoprazole
EP1947099A1 (fr) 2007-01-18 2008-07-23 LEK Pharmaceuticals D.D. Procédé pour l'élimination de solvant des sels d'oméprazole
EA016297B1 (ru) * 2007-06-15 2012-03-30 Эмкьюр Фармасьютикалз Лимитед Способ сульфоксидирования биологически активных соединений
CN101323609B (zh) * 2007-06-15 2013-05-01 成都福瑞生物工程有限公司 不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法
FR2920428B1 (fr) * 2007-08-29 2012-06-15 Univ Rouen Procede de dedoublement de sels de l'omeprazole
EP2262790B1 (fr) 2008-03-10 2017-06-07 Takeda Pharmaceutical Company Limited Cristal de composé de benzimidazole
WO2010058409A2 (fr) 2008-11-18 2010-05-27 Hetero Research Foundation Purification optique d'esoméprazole
KR101001646B1 (ko) * 2008-12-12 2010-12-17 한미약품 주식회사 (ｒ)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체
WO2011004387A2 (fr) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Procédé de préparation de formes polymorphes du dexlansoprazole
US8748619B2 (en) 2009-11-12 2014-06-10 Hetero Research Foundation Process for the resolution of omeprazole
US20130197232A1 (en) 2010-01-29 2013-08-01 Ranbaxy Laboratories Limited Process for the preparation of crystalline forms of dexlansoprazole
CA2956699C (fr) * 2014-07-30 2020-09-29 Aetas Pharma Co., Ltd. Isomere optique de derive de 1,4-benzothiazepine-1-oxyde, et composition pharmaceutique preparee a l'aide de celui-ci
EP3064495B1 (fr) * 2015-03-06 2016-12-14 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Procédé amélioré pour la préparation de l'esomeprazole optiquement pure

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU4640985A (en) * 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
ATE110069T1 (de) * 1989-11-29 1994-09-15 Toa Eiyo Ltd Cycloheptenopyridinderivate, verfahren zu ihrer herstellung und diese enthaltende antiulkusmitteln.
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
IS4232A (is) * 1993-12-06 1995-06-07 Astra Aktiebolag Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds

Also Published As

Publication number Publication date
PL324394A1 (en) 1998-05-25
TNSN96090A1 (fr) 2005-03-15
NZ311842A (en) 1998-12-23
CN1098261C (zh) 2003-01-08
CZ421197A3 (cs) 1998-06-17
EE9700368A (et) 1998-06-15
KR100451078B1 (ko) 2004-11-16
SK179397A3 (en) 1998-09-09
CZ295430B6 (cs) 2005-08-17
EP1498416A1 (fr) 2005-01-19
RU2144031C1 (ru) 2000-01-10
MA23921A1 (fr) 1996-12-31
JP4195507B2 (ja) 2008-12-10
TR199701754T1 (xx) 1998-04-21
RS49826B (sr) 2008-08-07
DE69637788D1 (de) 2009-02-05
CA2226184C (fr) 2008-08-05
MX9800160A (es) 1998-03-31
IS2666B (is) 2010-08-15
ES2318850T3 (es) 2009-05-01
WO1997002261A1 (fr) 1997-01-23
DK0836601T3 (da) 2009-03-16
IS4638A (is) 1997-12-22
HRP960232A2 (en) 1998-02-28
IL122811A0 (en) 1998-08-16
UA49838C2 (uk) 2002-10-15
EE03444B1 (et) 2001-06-15
YU37696A (sh) 1999-03-04
HUP9901717A3 (en) 2002-03-28
NO976030L (no) 1998-02-09
CA2226184A1 (fr) 1997-01-23
EP0836601A1 (fr) 1998-04-22
PL186702B1 (pl) 2004-02-27
SA96170103B1 (ar) 2006-07-30
PT836601E (pt) 2009-02-17
HK1010193A1 (en) 1999-06-17
NO313008B1 (no) 2002-07-29
CN1193971A (zh) 1998-09-23
KR19990028631A (ko) 1999-04-15
HUP9901717A2 (hu) 2000-04-28
DZ2057A1 (fr) 2002-10-20
JPH11508590A (ja) 1999-07-27
IL122811A (en) 2000-11-21
SI0836601T1 (sl) 2009-04-30
US5929244A (en) 1999-07-27
SK284780B6 (sk) 2005-11-03
EP0836601B1 (fr) 2008-12-24
AU698638B2 (en) 1998-11-05
NO976030D0 (no) 1997-12-22
TW444010B (en) 2001-07-01
ATE418549T1 (de) 2009-01-15
MY114018A (en) 2002-07-31
BR9609450A (pt) 1999-03-02
AU6324096A (en) 1997-02-05

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