SU1424723A3 - Фильтр дл удалени эритроцитов из крови на основе искусственных волокон и способ удалени эритроцитов из крови - Google Patents

Фильтр дл удалени эритроцитов из крови на основе искусственных волокон и способ удалени эритроцитов из крови Download PDF

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SU1424723A3
SU1424723A3 SU813315700A SU3315700A SU1424723A3 SU 1424723 A3 SU1424723 A3 SU 1424723A3 SU 813315700 A SU813315700 A SU 813315700A SU 3315700 A SU3315700 A SU 3315700A SU 1424723 A3 SU1424723 A3 SU 1424723A3
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red blood
blood
blood cells
filter
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Фогель Петер
Браун Ханс-Петер
Бергер Дитер
Вернер ВОЛЬФГАНГ
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Берингер Маннхайм Гмбх (Фирма)
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/20—Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2003—Glass or glassy material
    • B01D39/2017—Glass or glassy material the material being filamentary or fibrous
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

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Abstract

Изобретение относитс  к медицинской химии,, касаетс  фильтра и способа дл  удалени  эритроцитов из крови. Цель изобретени  - повышение степени удалени  эритроцитов. Дл  этого используют фильтр следующим образом. Крове нанос т на верхнюю сторону сло  1 искусственных волокон, фиксированную сеткой 5. Эритроциты и лейкоциты отдел ютс  в слое от плазмы, проход щей через слой 4 и попадающей в реакционный слой 2 или сборник. Сбор плазмы прекращают по достижении максимально вытекающего объема 50% от адсорбционного сло , после чего посредством незакрепленной части 4а сетки отдел ют слой искусственных волокон вместе с сеткой 5. Реакционный слой готов дл  дальнейшей работы с ним. В качестве искусственных волокон примен ют стекл н1«ое волокно диаметром 0,2-2,5 мкм при плотности упаковки 0,1-0,5 г/см . 2 с.п. ф-лы, 1 ил. О)

Description

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Изобретение относитс  к медицине, а именно к области медицинской химии и касаетс  фильтра и способа дл  удалени  эритроцитов из крови.
Целью изобретени   вл етс  повышение степени удалени  эритроцитов,
На чертеже изображен фильтр дл  осуществлени  способа удалени  эритроцитов из крови..
Слой 1 искусственных волокон, в качестве которых применено стекл нно волокно со средним диаметром 0,2- 2,5 мкм и плотностью упаковки 0,1- 0,5 г/см , размещен поверх реакцион- ного сло  2, расположенного на жесткой основе 3, и отделен от сло  2 тонким формоустойчивым и проницаемым дл  жидкости слоем 4, представл ющим собой сетку из тканых или сваленых пластмассовых нитей. Незакрепленна  часть этой сетки 4а предназначена дл  удалени  слоев 1 и 4 после отделени  эритроцитов и лейкоцитов из крови. Слой 1 фиксируетс  также свер ху сеткой 3.
Реакционный слой 2 может быть выполнен в виде обладающего всасывающей способностью носител  или пористой полимерной пленки. Основа 3 може быть выполнена из более толстой полимерной пленки, жесткого картона, стекла и т.п.
Фильтр работает следующим образом
Кровь нанос т на верхнюю сторону сло  1, фиксированную сеткой 5. Эритроциты , а также лейкоциты отдел ютс  в слое 1 от плазмы, котора  проходит
через слой 4 и попадает в реакционный слой 2 или сборник. Сбор плазмы прекращают после достижени  максимального вытекающего объема 50% от адсорбционного сло , после чего посредством незакрепленной части сетки 4а отдел ют слой 1 вместе с сеткой 5 Реакционный слой 2 готов к дальнейшей работе с ним.
Фильтр дл  удалени  эритроцитов из крови, характеризующийс  вьщ1еука- занными диаметром стекл нного волокна и плотностью упаковки его, позвол ет повысить степень отделени  эритроцитов от плазмы и практически исключить прохождение эритроцитов через фильтрующий слой.

Claims (2)

1.Фильтр дл  удалени  эритроцитов из крови на основе искусственных волокон, отличающийс  тем что, с целью поввшени  степени удалени  эритроцитов, в качестве искусственных волокон примен ют стекл нное волокно со средним диаметром 0,2- 2,5 мкм и плотностью упаковки 0,1- 0,5 г/см .
2.Способ удалени  эритроцитов из крови путем ее пропускани  через слой искусственных волокон, отличающийс  тем, что, с целью повышени  степени удалени  эритроцитов , пропускание прекращают после достижени  максимального вытекающего объема 50% от адсорбционного сло .
Составитель О.Кабанов Редактор А.Долинич Техред М.Ходанич Корректор С.Шекмар
Заказ 4700/58
Тираж 655
ВНИИПИ Государственного комитета СССР
по делам изобретений и открытий 113035, Москва, Ж-35, Раушска  наб., д. 4/5
Подписное
SU813315700A 1980-08-05 1981-08-04 Фильтр дл удалени эритроцитов из крови на основе искусственных волокон и способ удалени эритроцитов из крови SU1424723A3 (ru)

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Application Number Priority Date Filing Date Title
DE3029579A DE3029579C2 (de) 1980-08-05 1980-08-05 Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut

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SU1424723A3 true SU1424723A3 (ru) 1988-09-15

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US (1) US4477575A (ru)
EP (1) EP0045476B1 (ru)
JP (2) JPH0664054B2 (ru)
AT (1) ATE16218T1 (ru)
AU (1) AU525394B2 (ru)
CA (1) CA1177374A (ru)
CS (1) CS235005B2 (ru)
DD (1) DD201388A5 (ru)
DE (2) DE3029579C2 (ru)
DK (1) DK155636C (ru)
ES (1) ES504542A0 (ru)
FI (1) FI71999C (ru)
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IE (1) IE51623B1 (ru)
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CA1177374A (en) 1984-11-06
IL63492A (en) 1984-04-30
DE3029579A1 (de) 1982-02-18
AU525394B2 (en) 1982-11-04
ES8205558A1 (es) 1982-08-16
DK345381A (da) 1982-02-06
IE51623B1 (en) 1987-01-21
DD201388A5 (de) 1983-07-20
DK155636B (da) 1989-05-01
JPS5753661A (en) 1982-03-30
AU7364481A (en) 1982-02-11
JPH0854387A (ja) 1996-02-27
CS235005B2 (en) 1985-04-16
ZA815337B (en) 1982-08-25
EP0045476A1 (de) 1982-02-10
PL141490B1 (en) 1987-07-31
IE811779L (en) 1982-02-05
DE3172720D1 (en) 1985-11-28
ATE16218T1 (de) 1985-11-15
US4477575B1 (ru) 1992-04-21
ES504542A0 (es) 1982-08-16
FI71999B (fi) 1986-11-28
FI71999C (fi) 1987-03-09
JPH0664054B2 (ja) 1994-08-22
DE3029579C2 (de) 1985-12-12
DK155636C (da) 1989-09-25
EP0045476B1 (de) 1985-10-23
JP2680799B2 (ja) 1997-11-19
HU186398B (en) 1985-07-29
PL232469A1 (ru) 1982-04-26
US4477575A (en) 1984-10-16
FI812419L (fi) 1982-02-06
IL63492A0 (en) 1981-11-30

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