SK75094A3 - Naphthyridine derivatives - Google Patents
Naphthyridine derivatives Download PDFInfo
- Publication number
- SK75094A3 SK75094A3 SK750-94A SK75094A SK75094A3 SK 75094 A3 SK75094 A3 SK 75094A3 SK 75094 A SK75094 A SK 75094A SK 75094 A3 SK75094 A3 SK 75094A3
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- formula
- alkyl
- carbon atoms
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919127252A GB9127252D0 (en) | 1991-12-23 | 1991-12-23 | Therapeutic agents |
| PCT/EP1992/002901 WO1993013097A1 (en) | 1991-12-23 | 1992-12-12 | Anti-rheumatic naphthyridine derivatives |
| CN93109454A CN1096784A (zh) | 1991-12-23 | 1993-06-22 | 含取代4(5)-氨基-1,8-二氨杂萘的治疗剂 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK75094A3 true SK75094A3 (en) | 1995-04-12 |
Family
ID=36822317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK750-94A SK75094A3 (en) | 1991-12-23 | 1992-12-12 | Naphthyridine derivatives |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5464781A (hu) |
| EP (1) | EP0618916B1 (hu) |
| JP (1) | JP2527917B2 (hu) |
| CN (1) | CN1096784A (hu) |
| AT (1) | ATE171452T1 (hu) |
| AU (1) | AU656832B2 (hu) |
| BG (1) | BG98813A (hu) |
| CA (1) | CA2125858A1 (hu) |
| CZ (1) | CZ153594A3 (hu) |
| DE (1) | DE69227125T2 (hu) |
| FI (1) | FI943019A (hu) |
| GB (1) | GB9127252D0 (hu) |
| HR (1) | HRP921455A2 (hu) |
| HU (1) | HUT66971A (hu) |
| IL (1) | IL104169A0 (hu) |
| IN (1) | IN174405B (hu) |
| MX (1) | MX9207494A (hu) |
| NO (1) | NO942376L (hu) |
| NZ (1) | NZ246156A (hu) |
| SI (1) | SI9200408A (hu) |
| SK (1) | SK75094A3 (hu) |
| WO (1) | WO1993013097A1 (hu) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9312891D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| GB9318931D0 (en) * | 1993-09-14 | 1993-10-27 | Boots Co Plc | Therapeutic agents |
| GB9420168D0 (en) * | 1994-10-06 | 1994-11-23 | Boots Co Plc | Therapeutic agents |
| AR004010A1 (es) | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| US6809097B1 (en) * | 1996-09-25 | 2004-10-26 | Zeneca Limited | Quinoline derivatives inhibiting the effect of growth factors such as VEGF |
| RS49779B (sr) | 1998-01-12 | 2008-06-05 | Glaxo Group Limited, | Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze |
| US6166069A (en) * | 1998-05-12 | 2000-12-26 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6933299B1 (en) | 1999-07-09 | 2005-08-23 | Smithkline Beecham Corporation | Anilinoquinazolines as protein tyrosine kinase inhibitors |
| EP1192151B1 (en) | 1999-07-09 | 2007-11-07 | Glaxo Group Limited | Anilinoquinazolines as protein tyrosine kinase inhibitors |
| BR0109828A (pt) | 2000-04-07 | 2002-12-17 | Astrazeneca Ab | Composto, processo para a prepapação do mesmo ou de um sal deste, composição farmacêutica, uso do composto ou de um sal deste farmaceuticamente aceitável, e, método para a produção de um efeito antiangiogênico e/ou redutor da permeabilidade vascular em um animal de sangue quente em necessidade de tal tratamento |
| US6534656B2 (en) * | 2001-05-31 | 2003-03-18 | North Carolina State University | Short synthesis of pyridine-based pharmaceutical intermediates |
| JP2003329989A (ja) * | 2002-03-06 | 2003-11-19 | Nippon Telegr & Teleph Corp <Ntt> | 光送信装置 |
| GB0230018D0 (en) | 2002-12-23 | 2003-01-29 | Syngenta Ltd | Fungicides |
| US7618975B2 (en) | 2003-07-03 | 2009-11-17 | Myriad Pharmaceuticals, Inc. | 4-arylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| US8309562B2 (en) * | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
| UA82577C2 (en) | 2003-12-23 | 2008-04-25 | Пфайзер Инк. | Quinoline derivatives |
| US8258145B2 (en) * | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
| CA2592900A1 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
| ES2395386T3 (es) * | 2005-12-21 | 2013-02-12 | Abbott Laboratories | Compuestos antivirales |
| TW200738707A (en) * | 2005-12-21 | 2007-10-16 | Abbott Lab | Anti-viral compounds |
| AU2006330924B2 (en) * | 2005-12-21 | 2012-03-15 | Abbvie Inc. | Anti-viral compounds |
| DE602006015861D1 (de) * | 2005-12-21 | 2010-09-09 | Abbott Lab | Antivirale verbindungen |
| EP2345652A1 (en) | 2005-12-21 | 2011-07-20 | Abbott Laboratories | Antiviral compounds |
| TWI399380B (zh) | 2006-12-20 | 2013-06-21 | Abbott Lab | 抗病毒化合物 |
| US20110269758A1 (en) * | 2008-07-03 | 2011-11-03 | Merck Patent Gmbh | Naphthyridinones as protein kinase inhibitors |
| US8415333B2 (en) | 2009-02-24 | 2013-04-09 | Respiratorious Ab | Bronchodilating diazaheteroaryls |
| US8853235B2 (en) * | 2009-11-23 | 2014-10-07 | Senhwa Biosciences, Inc. | Polymorphs and salts of a kinase inhibitor |
| MY175079A (en) | 2010-04-02 | 2020-06-04 | Firmenich Incorporated | Sweet flavor modifier |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4466965A (en) * | 1982-07-26 | 1984-08-21 | American Hospital Supply Corporation | Phthalazine compounds, compositions and use |
| NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
| EP0222839A4 (en) * | 1985-05-17 | 1988-11-09 | Univ Australian | ANTI-MALARIA COMPOUNDS. |
| JPS6368568A (ja) * | 1986-09-10 | 1988-03-28 | Otsuka Pharmaceut Factory Inc | ｐ−アミノフエノ−ル誘導体 |
| DE3644825A1 (de) * | 1986-12-31 | 1988-07-14 | Basf Ag | Substituierte 1,8-naphthyridin-derivate und diese enthaltende fungizide |
| JPH07116187B2 (ja) * | 1987-07-22 | 1995-12-13 | シェリング・コーポレーション | 二環式化合物、それらを薬剤として使用すること、それらの製法、およびそれらの製造に有用な中間体 |
| GB8804443D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
| US4978661A (en) * | 1988-09-29 | 1990-12-18 | Innocenzo Caruso | Use of 6-halo-4-quinolone compounds and pharmaceutical compositions thereof for the preparation of a medicament for the therapeutical application in rheumatoid arthritis |
| GR900100380A (el) * | 1989-05-20 | 1991-10-10 | Fisons Plc | Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης. |
| AU634561B2 (en) * | 1989-07-27 | 1993-02-25 | Eli Lilly And Company | Naphthyridine derivatives |
| JP2988739B2 (ja) * | 1990-04-16 | 1999-12-13 | 協和醗酵工業株式会社 | １，８−ナフチリジン−２−オン誘導体 |
| JP3157077B2 (ja) * | 1994-02-16 | 2001-04-16 | 内山工業株式会社 | ベアリングシール |
-
1991
- 1991-12-23 GB GB919127252A patent/GB9127252D0/en active Pending
-
1992
- 1992-10-12 US US08/244,369 patent/US5464781A/en not_active Expired - Lifetime
- 1992-12-12 CZ CZ941535A patent/CZ153594A3/cs unknown
- 1992-12-12 SK SK750-94A patent/SK75094A3/sk unknown
- 1992-12-12 HU HU9401877A patent/HUT66971A/hu unknown
- 1992-12-12 DE DE69227125T patent/DE69227125T2/de not_active Expired - Fee Related
- 1992-12-12 AU AU31587/93A patent/AU656832B2/en not_active Ceased
- 1992-12-12 EP EP93900052A patent/EP0618916B1/en not_active Expired - Lifetime
- 1992-12-12 JP JP5511397A patent/JP2527917B2/ja not_active Expired - Fee Related
- 1992-12-12 CA CA002125858A patent/CA2125858A1/en not_active Abandoned
- 1992-12-12 AT AT93900052T patent/ATE171452T1/de not_active IP Right Cessation
- 1992-12-12 WO PCT/EP1992/002901 patent/WO1993013097A1/en active IP Right Grant
- 1992-12-12 NZ NZ246156A patent/NZ246156A/en unknown
- 1992-12-17 IN IN758MA1992 patent/IN174405B/en unknown
- 1992-12-18 IL IL104169A patent/IL104169A0/xx unknown
- 1992-12-22 HR HR921455A patent/HRP921455A2/hr not_active Application Discontinuation
- 1992-12-22 SI SI19929200408A patent/SI9200408A/sl unknown
- 1992-12-22 MX MX9207494A patent/MX9207494A/es unknown
-
1993
- 1993-06-22 CN CN93109454A patent/CN1096784A/zh active Pending
-
1994
- 1994-05-31 BG BG98813A patent/BG98813A/bg unknown
- 1994-06-22 FI FI943019A patent/FI943019A/fi not_active Application Discontinuation
- 1994-06-22 NO NO942376A patent/NO942376L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU3158793A (en) | 1993-07-28 |
| AU656832B2 (en) | 1995-02-16 |
| IL104169A0 (en) | 1993-05-13 |
| DE69227125T2 (de) | 1999-02-18 |
| BG98813A (bg) | 1995-05-31 |
| JP2527917B2 (ja) | 1996-08-28 |
| CZ153594A3 (en) | 1995-02-15 |
| SI9200408A (en) | 1993-09-30 |
| GB9127252D0 (en) | 1992-02-19 |
| CN1096784A (zh) | 1994-12-28 |
| CA2125858A1 (en) | 1993-07-08 |
| JPH07502280A (ja) | 1995-03-09 |
| EP0618916A1 (en) | 1994-10-12 |
| IN174405B (hu) | 1994-11-26 |
| HUT66971A (en) | 1995-01-30 |
| NO942376D0 (hu) | 1994-06-22 |
| HU9401877D0 (en) | 1994-09-28 |
| WO1993013097A1 (en) | 1993-07-08 |
| HRP921455A2 (en) | 1994-12-31 |
| DE69227125D1 (de) | 1998-10-29 |
| FI943019A0 (fi) | 1994-06-22 |
| FI943019A (fi) | 1994-06-22 |
| NO942376L (no) | 1994-06-22 |
| ATE171452T1 (de) | 1998-10-15 |
| NZ246156A (en) | 1996-01-26 |
| EP0618916B1 (en) | 1998-09-23 |
| US5464781A (en) | 1995-11-07 |
| MX9207494A (es) | 1993-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SK75094A3 (en) | Naphthyridine derivatives | |
| US5780482A (en) | Condensed 4-aminopyridines with antirheumatic activity | |
| US4753951A (en) | Condensed imidazopyridine derivatives useful as psychotropic agents | |
| UA74850C2 (en) | Amide derivatives as nmda receptor antagonists | |
| WO1999028320A1 (fr) | Derives de 2-aryl-8-oxodihydropurine, procede de production de ces derives, compositions medicales contenant ces derives, et intermediaires de ces derives | |
| HUT77348A (hu) | Tienopiridin- és tienopirimidinszármazékok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények | |
| CZ374692A3 (en) | Proteolytic enzymes inhibitors based on saccharin derivatives | |
| SK280822B6 (sk) | Imidazopyridíny, spôsob ich prípravy, farmaceutické prostriedky s ich obsahom a ich použitie | |
| HU198047B (en) | Process for production of new condensated derivatives of pirrol and medical preparatives containing these compounds as active substances | |
| JP4227197B2 (ja) | １Ｈ―ピリド［３，４―ｂ］インドール―４―カルボキサミド誘導体、その製造および治療上の適用 | |
| WO1998009960A1 (fr) | Derives de pyrimidine 2,4-bisubstitues, procede pour leur production et compositions medicales les contenant | |
| JP4248245B2 (ja) | ６−フェニルベンゾナフチリジン | |
| US4778801A (en) | Isoindolinone derivatives, production and use thereof | |
| JPS6377856A (ja) | 新規なフェニル、ピロリジン―２―イル置換５員複素環化合物およびその製造方法並びにこの化合物を有効成分とする抗精神病医薬組成物 | |
| NZ203217A (en) | Pyridobenzodiazepinone derivatives and pharmaceutical compositions | |
| US5102890A (en) | Pyrrole derivatives, their preparation and pharmaceutical compositions which contain them | |
| JPS6229585A (ja) | エーテル化若しくはエステル化しうるジヒドロキシ基により位置２で置換された４―ｏｈキノリンカルボン酸の新規の誘導体、その製造方法、及び医薬としてのその使用 | |
| CZ23799A3 (cs) | Farmaceutický přípravek obsahující 5HT2C antagonistu a D2 antagonistu | |
| JPS61205275A (ja) | 新規の８‐チオテトラヒドロキノリン誘導体及びそれらの塩 | |
| JPH08225531A (ja) | キノリンまたはキナゾリン誘導体を含んでなる医薬およびそれに用いる新規誘導体 | |
| WO1995007909A1 (en) | Alkyl-1-alkyl-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxylates as anti-rheumatic agents | |
| JPH11279157A (ja) | バルビツール酸誘導体およびそれらからなる骨・軟骨疾患予防・治療薬 | |
| JPS60100570A (ja) | 新規フラボン誘導体 | |
| SI9300584A (en) | Therapeutic agents for treatment of obesity and affective disorders and processes for their preparation | |
| JPH10503782A (ja) | 新規な５Ｈ−チアゾロ［３，２−ａ］ピリミジン−５−オン誘導体 |