HUT66971A - 4-amino-naphthyridine derivatives pharmaceutical compositions containing the same and process for the production of thereof - Google Patents

4-amino-naphthyridine derivatives pharmaceutical compositions containing the same and process for the production of thereof

Info

Publication number
HUT66971A
HUT66971A HU9401877A HU9401877A HUT66971A HU T66971 A HUT66971 A HU T66971A HU 9401877 A HU9401877 A HU 9401877A HU 9401877 A HU9401877 A HU 9401877A HU T66971 A HUT66971 A HU T66971A
Authority
HU
Hungary
Prior art keywords
alkyl
represents hydrogen
halo
alkoxy
pct
Prior art date
Application number
HU9401877A
Other languages
English (en)
Other versions
HU9401877D0 (en
Inventor
Bernard John Armitage
Ian Michael Hunneyball
John Gareth Bowen
Malcolm John Crossley
Bruce William Leslie
Thomas Kerr Miller
Michael Spowage
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of HU9401877D0 publication Critical patent/HU9401877D0/hu
Publication of HUT66971A publication Critical patent/HUT66971A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
HU9401877A 1991-12-23 1992-12-12 4-amino-naphthyridine derivatives pharmaceutical compositions containing the same and process for the production of thereof HUT66971A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919127252A GB9127252D0 (en) 1991-12-23 1991-12-23 Therapeutic agents
CN93109454A CN1096784A (zh) 1991-12-23 1993-06-22 含取代4(5)-氨基-1,8-二氨杂萘的治疗剂

Publications (2)

Publication Number Publication Date
HU9401877D0 HU9401877D0 (en) 1994-09-28
HUT66971A true HUT66971A (en) 1995-01-30

Family

ID=36822317

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9401877A HUT66971A (en) 1991-12-23 1992-12-12 4-amino-naphthyridine derivatives pharmaceutical compositions containing the same and process for the production of thereof

Country Status (22)

Country Link
US (1) US5464781A (hu)
EP (1) EP0618916B1 (hu)
JP (1) JP2527917B2 (hu)
CN (1) CN1096784A (hu)
AT (1) ATE171452T1 (hu)
AU (1) AU656832B2 (hu)
BG (1) BG98813A (hu)
CA (1) CA2125858A1 (hu)
CZ (1) CZ153594A3 (hu)
DE (1) DE69227125T2 (hu)
FI (1) FI943019A0 (hu)
GB (1) GB9127252D0 (hu)
HR (1) HRP921455A2 (hu)
HU (1) HUT66971A (hu)
IL (1) IL104169A0 (hu)
IN (1) IN174405B (hu)
MX (1) MX9207494A (hu)
NO (1) NO942376L (hu)
NZ (1) NZ246156A (hu)
SI (1) SI9200408A (hu)
SK (1) SK75094A3 (hu)
WO (1) WO1993013097A1 (hu)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9312891D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
GB9318931D0 (en) * 1993-09-14 1993-10-27 Boots Co Plc Therapeutic agents
GB9420168D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
AR004010A1 (es) 1995-10-11 1998-09-30 Glaxo Group Ltd Compuestos heterociclicos
JP2001500890A (ja) * 1996-09-25 2001-01-23 ゼネカ リミテッド Ｖｅｇｆのような成長因子の作用を阻害するキノリン誘導体
RS49779B (sr) 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
US6166069A (en) * 1998-05-12 2000-12-26 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
DE60037020T2 (de) 1999-07-09 2008-08-21 Glaxo Group Ltd., Greenford Anilinochinazoline als protein-tyrosin-kinasehemmer
US6933299B1 (en) 1999-07-09 2005-08-23 Smithkline Beecham Corporation Anilinoquinazolines as protein tyrosine kinase inhibitors
AU779695B2 (en) 2000-04-07 2005-02-10 Astrazeneca Ab Quinazoline compounds
US6534656B2 (en) * 2001-05-31 2003-03-18 North Carolina State University Short synthesis of pyridine-based pharmaceutical intermediates
JP2003329989A (ja) * 2002-03-06 2003-11-19 Nippon Telegr & Teleph Corp <Ntt> 光送信装置
GB0230018D0 (en) 2002-12-23 2003-01-29 Syngenta Ltd Fungicides
WO2006074147A2 (en) 2005-01-03 2006-07-13 Myriad Genetics, Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
WO2005003100A2 (en) 2003-07-03 2005-01-13 Myriad Genetics, Inc. 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
BRPI0418102A (pt) 2003-12-23 2007-04-27 Pfizer derivados de quinolina
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
WO2007081517A2 (en) 2005-12-21 2007-07-19 Abbott Laboratories Anti-viral compounds
TWI392676B (zh) * 2005-12-21 2013-04-11 Abbott Lab 抗病毒化合物、其製備方法及用途
EP2345652A1 (en) 2005-12-21 2011-07-20 Abbott Laboratories Antiviral compounds
RU2467007C2 (ru) * 2005-12-21 2012-11-20 Эбботт Лэборетриз Производные [1,8]нафтиридина, полезные в качестве ингибиторов репликации вируса hcv
KR20080080395A (ko) * 2005-12-21 2008-09-03 아보트 러보러터리즈 항바이러스 화합물
US8236950B2 (en) 2006-12-20 2012-08-07 Abbott Laboratories Anti-viral compounds
CN102083831B (zh) * 2008-07-03 2014-09-03 默克专利有限公司 用作aurora激酶抑制剂的萘啶酮
ES2432070T3 (es) 2009-02-24 2013-11-29 Respiratorius Ab Diazaheteroarilos broncodilatadores novedosos
WO2011063398A1 (en) * 2009-11-23 2011-05-26 Cylene Pharamaceuticals, Inc. Polymorphs and salts of a kinase inhibitor
SG10201507846YA (en) 2010-04-02 2015-10-29 Senomyx Inc Sweet flavor modifier

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466965A (en) * 1982-07-26 1984-08-21 American Hospital Supply Corporation Phthalazine compounds, compositions and use
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
WO1986006718A1 (en) * 1985-05-17 1986-11-20 The Australian National University Antimalarial compounds
JPS6368568A (ja) * 1986-09-10 1988-03-28 Otsuka Pharmaceut Factory Inc ｐ−アミノフエノ−ル誘導体
DE3644825A1 (de) * 1986-12-31 1988-07-14 Basf Ag Substituierte 1,8-naphthyridin-derivate und diese enthaltende fungizide
EP0362299A1 (en) * 1987-07-22 1990-04-11 Schering Corporation Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US4978661A (en) * 1988-09-29 1990-12-18 Innocenzo Caruso Use of 6-halo-4-quinolone compounds and pharmaceutical compositions thereof for the preparation of a medicament for the therapeutical application in rheumatoid arthritis
GR900100380A (el) * 1989-05-20 1991-10-10 Fisons Plc Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives
JP2988739B2 (ja) * 1990-04-16 1999-12-13 協和醗酵工業株式会社 １，８−ナフチリジン−２−オン誘導体
JP3157077B2 (ja) * 1994-02-16 2001-04-16 内山工業株式会社 ベアリングシール

Also Published As

Publication number Publication date
CZ153594A3 (en) 1995-02-15
US5464781A (en) 1995-11-07
NO942376L (no) 1994-06-22
DE69227125D1 (de) 1998-10-29
FI943019A (fi) 1994-06-22
GB9127252D0 (en) 1992-02-19
JPH07502280A (ja) 1995-03-09
ATE171452T1 (de) 1998-10-15
SI9200408A (en) 1993-09-30
DE69227125T2 (de) 1999-02-18
EP0618916B1 (en) 1998-09-23
MX9207494A (es) 1993-07-01
WO1993013097A1 (en) 1993-07-08
AU656832B2 (en) 1995-02-16
JP2527917B2 (ja) 1996-08-28
CN1096784A (zh) 1994-12-28
FI943019A0 (fi) 1994-06-22
HU9401877D0 (en) 1994-09-28
HRP921455A2 (en) 1994-12-31
IL104169A0 (en) 1993-05-13
NO942376D0 (hu) 1994-06-22
BG98813A (bg) 1995-05-31
SK75094A3 (en) 1995-04-12
NZ246156A (en) 1996-01-26
AU3158793A (en) 1993-07-28
IN174405B (hu) 1994-11-26
CA2125858A1 (en) 1993-07-08
EP0618916A1 (en) 1994-10-12

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Legal Events

Date Code Title Description
DFA9 Temporary protection cancelled due to abandonment