SK282663B6 - Diklavulanát diaminoéteru, spôsob jeho prípravy a farmaceutická kompozícia ho obsahujúca - Google Patents

Diklavulanát diaminoéteru, spôsob jeho prípravy a farmaceutická kompozícia ho obsahujúca Download PDF

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Publication number
SK282663B6
SK282663B6 SK776-97A SK77697A SK282663B6 SK 282663 B6 SK282663 B6 SK 282663B6 SK 77697 A SK77697 A SK 77697A SK 282663 B6 SK282663 B6 SK 282663B6
Authority
SK
Slovakia
Prior art keywords
salt
clavulanic acid
diaminoether
diclavulanate
ether
Prior art date
Application number
SK776-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK77697A3 (en
Inventor
George Leo Callewaert
Original Assignee
Spurcourt Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spurcourt Limited filed Critical Spurcourt Limited
Publication of SK77697A3 publication Critical patent/SK77697A3/sk
Publication of SK282663B6 publication Critical patent/SK282663B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
SK776-97A 1994-12-24 1995-12-22 Diklavulanát diaminoéteru, spôsob jeho prípravy a farmaceutická kompozícia ho obsahujúca SK282663B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426261.5A GB9426261D0 (en) 1994-12-24 1994-12-24 Clavulanic acid salts
PCT/GB1995/003039 WO1996020199A2 (en) 1994-12-24 1995-12-22 Diclavulanate salt with a diamino ether and process of preparation

Publications (2)

Publication Number Publication Date
SK77697A3 SK77697A3 (en) 1998-01-14
SK282663B6 true SK282663B6 (sk) 2002-11-06

Family

ID=10766624

Family Applications (1)

Application Number Title Priority Date Filing Date
SK776-97A SK282663B6 (sk) 1994-12-24 1995-12-22 Diklavulanát diaminoéteru, spôsob jeho prípravy a farmaceutická kompozícia ho obsahujúca

Country Status (40)

Country Link
US (1) US5786351A (de)
EP (1) EP0799233B1 (de)
JP (1) JPH10511386A (de)
KR (1) KR100416946B1 (de)
CN (1) CN1081640C (de)
AP (1) AP670A (de)
AR (1) AR004165A1 (de)
AT (1) ATE178606T1 (de)
AU (1) AU702968B2 (de)
BG (1) BG62971B1 (de)
BR (1) BR9510250A (de)
CA (1) CA2208520C (de)
CZ (1) CZ289287B6 (de)
DE (1) DE69508962T2 (de)
DK (1) DK0799233T3 (de)
EE (1) EE9700139A (de)
ES (1) ES2132756T3 (de)
FI (1) FI972464A (de)
GB (1) GB9426261D0 (de)
GE (1) GEP20002212B (de)
GR (1) GR3030629T3 (de)
HU (1) HUT77090A (de)
IL (1) IL116498A (de)
IS (1) IS4501A (de)
MD (1) MD1738F2 (de)
MY (1) MY114213A (de)
NO (1) NO313200B1 (de)
NZ (1) NZ297857A (de)
OA (1) OA10861A (de)
PL (1) PL182364B1 (de)
RO (1) RO118429B1 (de)
RU (1) RU2152948C1 (de)
SE (1) SE520665C2 (de)
SI (2) SI0799233T1 (de)
SK (1) SK282663B6 (de)
TJ (1) TJ269B (de)
TR (1) TR199501675A2 (de)
TW (1) TW401409B (de)
WO (1) WO1996020199A2 (de)
ZA (1) ZA9510880B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
PL333247A1 (en) * 1996-11-11 1999-11-22 Gist Brocades Bv Method of manufacturing of salts and esters of clavulan acid
AT404728B (de) * 1996-11-27 1999-02-25 Biochemie Gmbh Verfahren zur herstellung von clavulansäure-aminsalzen
WO2001087891A1 (en) 2000-05-13 2001-11-22 Smithkline Beecham P.L.C. Process for the purification of a salt of clavulanic acid
WO2009121869A1 (en) * 2008-04-02 2009-10-08 Dsm Ip Assets B.V. Diamine salts of carboxylic acids

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144242A (en) * 1975-02-07 1979-03-13 Glaxo Laboratories Limited Process for the purification of clavulanic acid
GB1578739A (en) * 1976-07-23 1980-11-05 Beecham Group Ltd Amine salts of clavulanic acid methods for their preparation and compositions containing them
US4255332A (en) * 1977-09-01 1981-03-10 Beecham Group Limited Process for the preparation of potassium clavulanate from lithium clavulanate
US4454069A (en) * 1979-08-24 1984-06-12 Beecham Group Limited Clavulanic acid salts and their preparation from the tertiary butyl amine salt
EP0026044B1 (de) 1979-08-24 1983-06-08 Beecham Group Plc Aminsalz der Clavulansäure, seine Herstellung und Verwendung
US5288861A (en) 1987-01-29 1994-02-22 Beecham Group Plc Potassium clavulanate in rosette form
NZ223316A (en) 1987-01-29 1989-10-27 Beecham Group Plc Crystalline potassium clavulanate and pharmaceutical compositions
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT400033B (de) * 1992-03-10 1995-09-25 Biochemie Gmbh Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
PL306371A1 (en) * 1993-03-26 1995-03-20 Gist Brocades Nv Diamine salts of clavulanic acid
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts

Also Published As

Publication number Publication date
CN1171111A (zh) 1998-01-21
CA2208520A1 (en) 1996-07-04
AP670A (en) 1998-09-04
SK77697A3 (en) 1998-01-14
EP0799233B1 (de) 1999-04-07
PL182364B1 (pl) 2001-12-31
KR100416946B1 (ko) 2004-05-10
IS4501A (is) 1997-06-09
NO972946L (no) 1997-06-23
HUT77090A (hu) 1998-03-02
GEP20002212B (en) 2000-08-25
DK0799233T3 (da) 1999-10-18
MD970230A (en) 1999-05-31
IL116498A (en) 2000-07-26
SE9702306D0 (sv) 1997-06-17
US5786351A (en) 1998-07-28
GB9426261D0 (en) 1995-02-22
TR199501675A2 (tr) 1997-07-21
WO1996020199A3 (en) 1996-09-12
EE9700139A (et) 1997-12-15
SI9520145A (sl) 1998-02-28
SI0799233T1 (en) 1999-08-31
RO118429B1 (ro) 2003-05-30
OA10861A (en) 2003-02-17
AU702968B2 (en) 1999-03-11
DE69508962D1 (de) 1999-05-12
EP0799233A2 (de) 1997-10-08
DE69508962T2 (de) 1999-08-12
JPH10511386A (ja) 1998-11-04
CN1081640C (zh) 2002-03-27
AU4311096A (en) 1996-07-19
ZA9510880B (en) 1996-08-07
RU2152948C1 (ru) 2000-07-20
CA2208520C (en) 2003-10-07
NZ297857A (en) 1997-11-24
CZ289287B6 (cs) 2001-12-12
IL116498A0 (en) 1996-03-31
CZ192097A3 (cs) 1998-08-12
MD1738F2 (ro) 2001-09-30
NO972946D0 (no) 1997-06-23
SE520665C2 (sv) 2003-08-05
SE9702306L (sv) 1997-08-25
MX9704693A (es) 1998-06-30
AR004165A1 (es) 1998-11-04
ATE178606T1 (de) 1999-04-15
TJ269B (en) 2000-08-07
FI972464A0 (fi) 1997-06-10
AP9701013A0 (en) 1997-07-31
GR3030629T3 (en) 1999-10-29
ES2132756T3 (es) 1999-08-16
TW401409B (en) 2000-08-11
PL321092A1 (en) 1997-11-24
NO313200B1 (no) 2002-08-26
MY114213A (en) 2002-08-30
WO1996020199A2 (en) 1996-07-04
BR9510250A (pt) 1997-11-04
FI972464A (fi) 1997-08-21
BG62971B1 (bg) 2000-12-29
BG101671A (en) 1998-09-30

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