DK0799233T3 - Diclavulansyresalte med diaminoethere og fremgangsmåde til fremstilling deraf - Google Patents

Diclavulansyresalte med diaminoethere og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0799233T3
DK0799233T3 DK95941809T DK95941809T DK0799233T3 DK 0799233 T3 DK0799233 T3 DK 0799233T3 DK 95941809 T DK95941809 T DK 95941809T DK 95941809 T DK95941809 T DK 95941809T DK 0799233 T3 DK0799233 T3 DK 0799233T3
Authority
DK
Denmark
Prior art keywords
diclavulanic
preparation
acid salts
diamino
ethers
Prior art date
Application number
DK95941809T
Other languages
Danish (da)
English (en)
Inventor
George Leo Callewaert
Original Assignee
Spurcourt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spurcourt Ltd filed Critical Spurcourt Ltd
Application granted granted Critical
Publication of DK0799233T3 publication Critical patent/DK0799233T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
DK95941809T 1994-12-24 1995-12-22 Diclavulansyresalte med diaminoethere og fremgangsmåde til fremstilling deraf DK0799233T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426261.5A GB9426261D0 (en) 1994-12-24 1994-12-24 Clavulanic acid salts
PCT/GB1995/003039 WO1996020199A2 (en) 1994-12-24 1995-12-22 Diclavulanate salt with a diamino ether and process of preparation

Publications (1)

Publication Number Publication Date
DK0799233T3 true DK0799233T3 (da) 1999-10-18

Family

ID=10766624

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95941809T DK0799233T3 (da) 1994-12-24 1995-12-22 Diclavulansyresalte med diaminoethere og fremgangsmåde til fremstilling deraf

Country Status (40)

Country Link
US (1) US5786351A (de)
EP (1) EP0799233B1 (de)
JP (1) JPH10511386A (de)
KR (1) KR100416946B1 (de)
CN (1) CN1081640C (de)
AP (1) AP670A (de)
AR (1) AR004165A1 (de)
AT (1) ATE178606T1 (de)
AU (1) AU702968B2 (de)
BG (1) BG62971B1 (de)
BR (1) BR9510250A (de)
CA (1) CA2208520C (de)
CZ (1) CZ289287B6 (de)
DE (1) DE69508962T2 (de)
DK (1) DK0799233T3 (de)
EE (1) EE9700139A (de)
ES (1) ES2132756T3 (de)
FI (1) FI972464A (de)
GB (1) GB9426261D0 (de)
GE (1) GEP20002212B (de)
GR (1) GR3030629T3 (de)
HU (1) HUT77090A (de)
IL (1) IL116498A (de)
IS (1) IS4501A (de)
MD (1) MD1738F2 (de)
MY (1) MY114213A (de)
NO (1) NO313200B1 (de)
NZ (1) NZ297857A (de)
OA (1) OA10861A (de)
PL (1) PL182364B1 (de)
RO (1) RO118429B1 (de)
RU (1) RU2152948C1 (de)
SE (1) SE520665C2 (de)
SI (2) SI0799233T1 (de)
SK (1) SK282663B6 (de)
TJ (1) TJ269B (de)
TR (1) TR199501675A2 (de)
TW (1) TW401409B (de)
WO (1) WO1996020199A2 (de)
ZA (1) ZA9510880B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
CN1238776A (zh) * 1996-11-11 1999-12-15 吉斯特-布罗卡迪斯有限公司 制备棒酸盐和酯的方法
AT404728B (de) * 1996-11-27 1999-02-25 Biochemie Gmbh Verfahren zur herstellung von clavulansäure-aminsalzen
ES2225524T5 (es) 2000-05-13 2009-03-01 Smithkline Beecham Plc Procedimiento para la purificacion de una sal de acido clavulanico.
US8461327B2 (en) 2008-04-02 2013-06-11 Dsm Sinochem Pharmaceuticals Netherlands B.V. Diamine salts of carboxylic acids

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144242A (en) * 1975-02-07 1979-03-13 Glaxo Laboratories Limited Process for the purification of clavulanic acid
GB1578739A (en) * 1976-07-23 1980-11-05 Beecham Group Ltd Amine salts of clavulanic acid methods for their preparation and compositions containing them
US4255332A (en) * 1977-09-01 1981-03-10 Beecham Group Limited Process for the preparation of potassium clavulanate from lithium clavulanate
US4454069A (en) * 1979-08-24 1984-06-12 Beecham Group Limited Clavulanic acid salts and their preparation from the tertiary butyl amine salt
EP0026044B1 (de) 1979-08-24 1983-06-08 Beecham Group Plc Aminsalz der Clavulansäure, seine Herstellung und Verwendung
US5288861A (en) 1987-01-29 1994-02-22 Beecham Group Plc Potassium clavulanate in rosette form
GR1000035B (el) 1987-01-29 1990-03-12 Beecham Group Plc Κλαβουλανικο καλιο.
ES2010143A6 (es) * 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT400033B (de) 1992-03-10 1995-09-25 Biochemie Gmbh Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
RO112113B1 (ro) 1993-03-26 1997-05-30 Gist Brocades Nv Saruri diaminice ale acidului clavulanic si procedeu pentru prepararea acestora
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts

Also Published As

Publication number Publication date
GR3030629T3 (en) 1999-10-29
IS4501A (is) 1997-06-09
TJ269B (en) 2000-08-07
ATE178606T1 (de) 1999-04-15
AP9701013A0 (en) 1997-07-31
KR100416946B1 (ko) 2004-05-10
IL116498A0 (en) 1996-03-31
HUT77090A (hu) 1998-03-02
MD1738F2 (ro) 2001-09-30
TR199501675A2 (tr) 1997-07-21
DE69508962T2 (de) 1999-08-12
SE9702306D0 (sv) 1997-06-17
AU4311096A (en) 1996-07-19
IL116498A (en) 2000-07-26
AR004165A1 (es) 1998-11-04
GB9426261D0 (en) 1995-02-22
CA2208520C (en) 2003-10-07
CZ192097A3 (cs) 1998-08-12
JPH10511386A (ja) 1998-11-04
NO972946L (no) 1997-06-23
EP0799233A2 (de) 1997-10-08
RO118429B1 (ro) 2003-05-30
PL182364B1 (pl) 2001-12-31
EP0799233B1 (de) 1999-04-07
WO1996020199A2 (en) 1996-07-04
BG62971B1 (bg) 2000-12-29
WO1996020199A3 (en) 1996-09-12
NZ297857A (en) 1997-11-24
NO972946D0 (no) 1997-06-23
SK282663B6 (sk) 2002-11-06
BR9510250A (pt) 1997-11-04
ES2132756T3 (es) 1999-08-16
DE69508962D1 (de) 1999-05-12
CZ289287B6 (cs) 2001-12-12
EE9700139A (et) 1997-12-15
CA2208520A1 (en) 1996-07-04
CN1081640C (zh) 2002-03-27
FI972464A0 (fi) 1997-06-10
NO313200B1 (no) 2002-08-26
MX9704693A (es) 1998-06-30
PL321092A1 (en) 1997-11-24
MY114213A (en) 2002-08-30
SE9702306L (sv) 1997-08-25
SK77697A3 (en) 1998-01-14
ZA9510880B (en) 1996-08-07
OA10861A (en) 2003-02-17
FI972464A (fi) 1997-08-21
MD970230A (en) 1999-05-31
CN1171111A (zh) 1998-01-21
RU2152948C1 (ru) 2000-07-20
AU702968B2 (en) 1999-03-11
BG101671A (en) 1998-09-30
AP670A (en) 1998-09-04
SI9520145A (sl) 1998-02-28
GEP20002212B (en) 2000-08-25
SI0799233T1 (en) 1999-08-31
SE520665C2 (sv) 2003-08-05
US5786351A (en) 1998-07-28
TW401409B (en) 2000-08-11

Similar Documents

Publication Publication Date Title
EE03399B1 (et) Teraapias kasutatavad spiro-asabitsüklilised ühendid ja nende valmistamise protsess
FI111263B (fi) Uudet erytromysiinijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä sekä menetelmässä käytettävät välituoteamiinit
NO963015L (no) Tetracykliske derivater, fremgangsmåte for fremstilling og anvendelse
NO976072L (no) Propiofenonderivater og fremgangsmÕte for fremstilling derav
IS3720A7 (is) Afleiður dialkoxy-pyridinyl-benzimidazole, aðferðvið lögun þeirra og lyfjafræðileg notkun
TR199501616A2 (tr) Gelistirilmis emici özelliklere sahip sitosan tuzlari ve onlarin hazirlanmasi icin islem.
NO972475D0 (no) Ny antitrombotisk formulering, fremgangsmåte for dens fremstilling og anvendelse derav
IT8448266A0 (it) Apparecchio e procedimento per il posizionamento, in particolare l'allineamento delle estremita' di calze
DK26784A (da) Aminosyrederivater, deres fremstilling og anvendelse
NO962545D0 (no) Krystallinske N-acetyl-neuraminsyrederivater og fremgangsmåter for fremstilling derav
NO983954D0 (no) Triazintiolderivat med perfluorgruppe, fremgangsmåte for fremstilling og anvendelse av dette
AR243849A1 (es) Aparato y procedimiento para fabricar acido peroxomonosulfurico
IS1877B (is) Aðferð til framleiðslu á N-metýl-3-(1-metýl-4-píperidinýl)-1H-indól-5- etansúlfonamíð og lífeðlisfræðilega viðunandi söltum þess og lausnum þeirra
DK0799233T3 (da) Diclavulansyresalte med diaminoethere og fremgangsmåde til fremstilling deraf
IL105100A0 (en) Glutamic acid derivatives and process for their preparation
ZA908724B (en) Substituted amino acid amide derivatives,their preparation and use
IS3725A7 (is) Amínósýruafleiður og aðferð til framleiðslu þeirra
NO20006542D0 (no) N-fenyl-N'-fenylpropylpiperazinderivater og fremgangsmåte for fremstilling derav
DK0492667T3 (da) 1,4-Benzothiazin-2-eddikesyrederivater, fremgangsmåder til fremstilling deraf og anvendelse deraf
HU912979D0 (en) New amino acid derivatives and method for producing them
DK165729C (da) Sulpiridpraeparat paa oralt indgivelig galenisk form og fremgangsmaade til fremstilling deraf
GB9409395D0 (en) Sialic acid derivatives and process for their preparation
ZA917518B (en) Substituted amino acid derivatives their preparation and use
IL129330A (en) Phenoxy-phenylsulfonic acid derivatives and process for their preparation
GB9104501D0 (en) 5-phenyl-1h-pyrazol-4-propionic acid derivatives,their preparation and their use