SI0799233T1 - Diclavulanic acid salts with diamino ethers and process for their preparation - Google Patents

Diclavulanic acid salts with diamino ethers and process for their preparation

Info

Publication number
SI0799233T1
SI0799233T1 SI9530245T SI9530245T SI0799233T1 SI 0799233 T1 SI0799233 T1 SI 0799233T1 SI 9530245 T SI9530245 T SI 9530245T SI 9530245 T SI9530245 T SI 9530245T SI 0799233 T1 SI0799233 T1 SI 0799233T1
Authority
SI
Slovenia
Prior art keywords
diclavulanic
preparation
acid salts
diamino
ethers
Prior art date
Application number
SI9530245T
Other languages
English (en)
Slovenian (sl)
Inventor
George Leo Callewaert
Original Assignee
Spurcourt Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spurcourt Limited filed Critical Spurcourt Limited
Publication of SI0799233T1 publication Critical patent/SI0799233T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
SI9530245T 1994-12-24 1995-12-22 Diclavulanic acid salts with diamino ethers and process for their preparation SI0799233T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9426261.5A GB9426261D0 (en) 1994-12-24 1994-12-24 Clavulanic acid salts
PCT/GB1995/003039 WO1996020199A2 (en) 1994-12-24 1995-12-22 Diclavulanate salt with a diamino ether and process of preparation
EP95941809A EP0799233B1 (en) 1994-12-24 1995-12-22 Diclavulanic acid salts with diamino ethers and process for their preparation

Publications (1)

Publication Number Publication Date
SI0799233T1 true SI0799233T1 (en) 1999-08-31

Family

ID=10766624

Family Applications (2)

Application Number Title Priority Date Filing Date
SI9520145A SI9520145A (sl) 1994-12-24 1995-12-22 Diklavulanatne soli z diamino etrom in postopek priprave
SI9530245T SI0799233T1 (en) 1994-12-24 1995-12-22 Diclavulanic acid salts with diamino ethers and process for their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI9520145A SI9520145A (sl) 1994-12-24 1995-12-22 Diklavulanatne soli z diamino etrom in postopek priprave

Country Status (40)

Country Link
US (1) US5786351A (xx)
EP (1) EP0799233B1 (xx)
JP (1) JPH10511386A (xx)
KR (1) KR100416946B1 (xx)
CN (1) CN1081640C (xx)
AP (1) AP670A (xx)
AR (1) AR004165A1 (xx)
AT (1) ATE178606T1 (xx)
AU (1) AU702968B2 (xx)
BG (1) BG62971B1 (xx)
BR (1) BR9510250A (xx)
CA (1) CA2208520C (xx)
CZ (1) CZ289287B6 (xx)
DE (1) DE69508962T2 (xx)
DK (1) DK0799233T3 (xx)
EE (1) EE9700139A (xx)
ES (1) ES2132756T3 (xx)
FI (1) FI972464A (xx)
GB (1) GB9426261D0 (xx)
GE (1) GEP20002212B (xx)
GR (1) GR3030629T3 (xx)
HU (1) HUT77090A (xx)
IL (1) IL116498A (xx)
IS (1) IS4501A (xx)
MD (1) MD1738F2 (xx)
MY (1) MY114213A (xx)
NO (1) NO313200B1 (xx)
NZ (1) NZ297857A (xx)
OA (1) OA10861A (xx)
PL (1) PL182364B1 (xx)
RO (1) RO118429B1 (xx)
RU (1) RU2152948C1 (xx)
SE (1) SE520665C2 (xx)
SI (2) SI9520145A (xx)
SK (1) SK282663B6 (xx)
TJ (1) TJ269B (xx)
TR (1) TR199501675A2 (xx)
TW (1) TW401409B (xx)
WO (1) WO1996020199A2 (xx)
ZA (1) ZA9510880B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9400107A (en) 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500134B (sl) 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
EP0937084A1 (en) * 1996-11-11 1999-08-25 Gist-Brocades B.V. Process for the preparation of salts and esters of clavulanic acid
AT404728B (de) * 1996-11-27 1999-02-25 Biochemie Gmbh Verfahren zur herstellung von clavulansäure-aminsalzen
EP1284978B2 (en) 2000-05-13 2008-09-10 Smithkline Beecham Plc Process for the purification of a salt of clavulanic acid
US8461327B2 (en) * 2008-04-02 2013-06-11 Dsm Sinochem Pharmaceuticals Netherlands B.V. Diamine salts of carboxylic acids

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144242A (en) * 1975-02-07 1979-03-13 Glaxo Laboratories Limited Process for the purification of clavulanic acid
GB1578739A (en) * 1976-07-23 1980-11-05 Beecham Group Ltd Amine salts of clavulanic acid methods for their preparation and compositions containing them
US4255332A (en) * 1977-09-01 1981-03-10 Beecham Group Limited Process for the preparation of potassium clavulanate from lithium clavulanate
US4454069A (en) * 1979-08-24 1984-06-12 Beecham Group Limited Clavulanic acid salts and their preparation from the tertiary butyl amine salt
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
EP0277008B1 (en) 1987-01-29 1995-06-14 Beecham Group Plc Process for crystallization of potassium clavulanate
US5288861A (en) 1987-01-29 1994-02-22 Beecham Group Plc Potassium clavulanate in rosette form
ES2010143A6 (es) 1989-03-01 1989-10-16 Pharma Mar S A Pharmar Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT400033B (de) * 1992-03-10 1995-09-25 Biochemie Gmbh Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
SK279918B6 (sk) 1993-03-26 1999-05-07 Gist-Brocades N.V. Soli kyseliny klavulánovej s diamínmi, spôsob ich
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts

Also Published As

Publication number Publication date
MD970230A (en) 1999-05-31
ES2132756T3 (es) 1999-08-16
SI9520145A (sl) 1998-02-28
MD1738F2 (ro) 2001-09-30
SE9702306D0 (sv) 1997-06-17
NO972946D0 (no) 1997-06-23
NZ297857A (en) 1997-11-24
NO972946L (no) 1997-06-23
AU702968B2 (en) 1999-03-11
KR100416946B1 (ko) 2004-05-10
DE69508962T2 (de) 1999-08-12
WO1996020199A3 (en) 1996-09-12
EE9700139A (et) 1997-12-15
GEP20002212B (en) 2000-08-25
IL116498A0 (en) 1996-03-31
BG101671A (en) 1998-09-30
DE69508962D1 (de) 1999-05-12
EP0799233A2 (en) 1997-10-08
NO313200B1 (no) 2002-08-26
ATE178606T1 (de) 1999-04-15
TW401409B (en) 2000-08-11
MY114213A (en) 2002-08-30
FI972464A0 (fi) 1997-06-10
IS4501A (is) 1997-06-09
AR004165A1 (es) 1998-11-04
WO1996020199A2 (en) 1996-07-04
MX9704693A (es) 1998-06-30
RU2152948C1 (ru) 2000-07-20
AU4311096A (en) 1996-07-19
GR3030629T3 (en) 1999-10-29
CZ289287B6 (cs) 2001-12-12
SE520665C2 (sv) 2003-08-05
CZ192097A3 (cs) 1998-08-12
JPH10511386A (ja) 1998-11-04
SK77697A3 (en) 1998-01-14
SE9702306L (sv) 1997-08-25
BG62971B1 (bg) 2000-12-29
ZA9510880B (en) 1996-08-07
PL321092A1 (en) 1997-11-24
US5786351A (en) 1998-07-28
HUT77090A (hu) 1998-03-02
CN1171111A (zh) 1998-01-21
RO118429B1 (ro) 2003-05-30
AP9701013A0 (en) 1997-07-31
CA2208520C (en) 2003-10-07
TJ269B (en) 2000-08-07
TR199501675A2 (tr) 1997-07-21
DK0799233T3 (da) 1999-10-18
OA10861A (en) 2003-02-17
FI972464A (fi) 1997-08-21
BR9510250A (pt) 1997-11-04
SK282663B6 (sk) 2002-11-06
EP0799233B1 (en) 1999-04-07
CN1081640C (zh) 2002-03-27
CA2208520A1 (en) 1996-07-04
AP670A (en) 1998-09-04
PL182364B1 (pl) 2001-12-31
IL116498A (en) 2000-07-26
GB9426261D0 (en) 1995-02-22

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