SK281577B6 - Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze - Google Patents

Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze Download PDF

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Publication number
SK281577B6
SK281577B6 SK1287-95A SK128795A SK281577B6 SK 281577 B6 SK281577 B6 SK 281577B6 SK 128795 A SK128795 A SK 128795A SK 281577 B6 SK281577 B6 SK 281577B6
Authority
SK
Slovakia
Prior art keywords
alkyl
pyran
tetrahydro
phenyl
mmol
Prior art date
Application number
SK1287-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK128795A3 (en
Inventor
Rodney William Stevens
Mano Takashi
Nakao Kazunari
Okumura Yoshiyuki
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of SK128795A3 publication Critical patent/SK128795A3/sk
Publication of SK281577B6 publication Critical patent/SK281577B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK1287-95A 1994-10-18 1994-10-18 Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze SK281577B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9401747 1994-10-18

Publications (2)

Publication Number Publication Date
SK128795A3 SK128795A3 (en) 1996-07-03
SK281577B6 true SK281577B6 (sk) 2001-05-10

Family

ID=14098722

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1287-95A SK281577B6 (sk) 1994-10-18 1994-10-18 Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze

Country Status (31)

Country Link
EP (1) EP0787127B1 (cs)
JP (1) JP3032579B2 (cs)
CN (1) CN1093536C (cs)
AT (1) ATE198474T1 (cs)
AU (1) AU681520B2 (cs)
BG (1) BG61768B1 (cs)
CA (1) CA2202057C (cs)
CO (1) CO4480026A1 (cs)
CZ (1) CZ287350B6 (cs)
DE (1) DE69519804T2 (cs)
DK (1) DK0787127T3 (cs)
ES (1) ES2153033T3 (cs)
FI (1) FI971632A0 (cs)
GR (1) GR3035471T3 (cs)
HU (1) HU221543B (cs)
IL (1) IL115581A (cs)
LV (1) LV11468B (cs)
MY (1) MY114680A (cs)
NO (1) NO314629B1 (cs)
NZ (1) NZ285163A (cs)
PE (1) PE49196A1 (cs)
PL (1) PL180104B1 (cs)
RU (1) RU2136666C1 (cs)
SI (1) SI9500392A (cs)
SK (1) SK281577B6 (cs)
TR (1) TR199501274A2 (cs)
TW (1) TW411339B (cs)
UA (1) UA45312C2 (cs)
WO (1) WO1996011911A1 (cs)
YU (1) YU65995A (cs)
ZA (1) ZA958748B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239285B1 (en) 1998-02-06 2001-05-29 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
US6194585B1 (en) * 1998-12-22 2001-02-27 Pfizer Inc. Process for preparing 5-lipoxygenase inhibitors
US6346624B1 (en) * 1999-08-31 2002-02-12 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
US6344563B1 (en) * 1999-08-31 2002-02-05 Timothy Norris Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
SG87145A1 (en) * 1999-08-31 2002-03-19 Pfizer Prod Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
CN1321112C (zh) 2000-03-24 2007-06-13 欧洲凯尔特股份有限公司 作为钠通道阻滞剂的芳基取代的吡唑、三唑和四唑化合物
DE60234822D1 (de) * 2001-04-20 2010-02-04 Novozymes As Lipoxygenase-varianten und ihre verwendung
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
CA2667566C (en) * 2006-11-27 2012-01-03 Pfizer Products Inc. Pyrazole analogs
AU2008331199A1 (en) * 2007-11-26 2009-06-04 Pfizer Inc. Pyrazole derivatives as 5-LO inhibitors
IN2014MN01839A (cs) * 2012-02-28 2015-07-03 Piramal Entpr Ltd
PT3762368T (pt) 2018-03-08 2022-05-06 Incyte Corp Compostos de aminopirazina diol como inibidores de pi3k-y
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0462830B1 (en) * 1990-06-21 1995-10-18 Zeneca Limited Cyclic ether derivatives
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
EP0505122A1 (en) * 1991-03-21 1992-09-23 Zeneca Limited Alpha, alpha-dialkylbenzyl derivatives
EP0540165A1 (en) * 1991-10-03 1993-05-05 Zeneca Limited Alkanoic acid derivatives
CN1050840C (zh) * 1993-06-14 2000-03-29 美国辉瑞有限公司 咪唑脂氧合酶抑制剂

Also Published As

Publication number Publication date
SI9500392A (en) 1996-08-31
SK128795A3 (en) 1996-07-03
LV11468B (en) 1996-12-20
DE69519804T2 (de) 2001-04-19
LV11468A (lv) 1996-08-20
PL319727A1 (en) 1997-08-18
ES2153033T3 (es) 2001-02-16
EP0787127B1 (en) 2001-01-03
NO971773D0 (no) 1997-04-17
ZA958748B (en) 1997-04-17
PE49196A1 (es) 1996-11-21
UA45312C2 (uk) 2002-04-15
WO1996011911A1 (en) 1996-04-25
TW411339B (en) 2000-11-11
BG100070A (bg) 1996-05-31
NO314629B1 (no) 2003-04-22
NO971773L (no) 1997-06-17
JP3032579B2 (ja) 2000-04-17
NZ285163A (en) 1998-08-26
IL115581A0 (en) 1996-01-19
AU2417495A (en) 1996-05-06
AU681520B2 (en) 1997-08-28
DK0787127T3 (da) 2001-02-05
HUT77363A (hu) 1998-03-30
RU2136666C1 (ru) 1999-09-10
CN1093536C (zh) 2002-10-30
FI971632A (fi) 1997-04-17
HU221543B (hu) 2002-11-28
GR3035471T3 (en) 2001-05-31
CA2202057C (en) 2001-10-09
CZ117797A3 (cs) 1998-06-17
CO4480026A1 (es) 1997-07-09
JPH11507322A (ja) 1999-06-29
MY114680A (en) 2002-12-31
DE69519804D1 (de) 2001-02-08
ATE198474T1 (de) 2001-01-15
PL180104B1 (pl) 2000-12-29
EP0787127A1 (en) 1997-08-06
CZ287350B6 (en) 2000-10-11
FI971632A0 (fi) 1997-04-17
CA2202057A1 (en) 1996-04-25
YU65995A (sh) 1999-06-15
CN1169722A (zh) 1998-01-07
TR199501274A2 (tr) 1996-06-21
BG61768B1 (bg) 1998-05-29
IL115581A (en) 1999-10-28

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