LV11468A - 5-Lipoksigenazes inhibitors - Google Patents

5-Lipoksigenazes inhibitors

Info

Publication number
LV11468A
LV11468A LV950313A LV950313A LV11468A LV 11468 A LV11468 A LV 11468A LV 950313 A LV950313 A LV 950313A LV 950313 A LV950313 A LV 950313A LV 11468 A LV11468 A LV 11468A
Authority
LV
Latvia
Prior art keywords
alkyl
halo
cyano
alkylene
hydroxy
Prior art date
Application number
LV950313A
Other languages
English (en)
Other versions
LV11468B (en
Inventor
Rodney W Stevens
Takashi Mano
Kazunari Nakao
Yoshiyuki Okumura
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of LV11468A publication Critical patent/LV11468A/lv
Publication of LV11468B publication Critical patent/LV11468B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
LVP-95-313A 1994-10-18 1995-10-17 5-lipoxygenase inhibitors LV11468B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9401747 1994-10-18

Publications (2)

Publication Number Publication Date
LV11468A true LV11468A (lv) 1996-08-20
LV11468B LV11468B (en) 1996-12-20

Family

ID=14098722

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-95-313A LV11468B (en) 1994-10-18 1995-10-17 5-lipoxygenase inhibitors

Country Status (31)

Country Link
EP (1) EP0787127B1 (lv)
JP (1) JP3032579B2 (lv)
CN (1) CN1093536C (lv)
AT (1) ATE198474T1 (lv)
AU (1) AU681520B2 (lv)
BG (1) BG61768B1 (lv)
CA (1) CA2202057C (lv)
CO (1) CO4480026A1 (lv)
CZ (1) CZ287350B6 (lv)
DE (1) DE69519804T2 (lv)
DK (1) DK0787127T3 (lv)
ES (1) ES2153033T3 (lv)
FI (1) FI971632A (lv)
GR (1) GR3035471T3 (lv)
HU (1) HU221543B (lv)
IL (1) IL115581A (lv)
LV (1) LV11468B (lv)
MY (1) MY114680A (lv)
NO (1) NO314629B1 (lv)
NZ (1) NZ285163A (lv)
PE (1) PE49196A1 (lv)
PL (1) PL180104B1 (lv)
RU (1) RU2136666C1 (lv)
SI (1) SI9500392A (lv)
SK (1) SK281577B6 (lv)
TR (1) TR199501274A2 (lv)
TW (1) TW411339B (lv)
UA (1) UA45312C2 (lv)
WO (1) WO1996011911A1 (lv)
YU (1) YU65995A (lv)
ZA (1) ZA958748B (lv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239285B1 (en) 1998-02-06 2001-05-29 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
US6194585B1 (en) * 1998-12-22 2001-02-27 Pfizer Inc. Process for preparing 5-lipoxygenase inhibitors
US6346624B1 (en) * 1999-08-31 2002-02-12 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
SG87145A1 (en) * 1999-08-31 2002-03-19 Pfizer Prod Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
US6344563B1 (en) * 1999-08-31 2002-02-05 Timothy Norris Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
PL214230B1 (pl) * 2000-03-24 2013-07-31 Euro Celtique Sa Podstawione arylem pirazole i triazole, kompozycja farmaceutyczna je zawierajaca oraz ich zastosowanie
DK1383874T3 (da) * 2001-04-20 2010-05-03 Novozymes As Varianter af lipogygenase og deres anvendelse
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
NZ576376A (en) * 2006-11-27 2011-02-25 Pfizer Prod Inc Pyrazole analogs
EP2225229A1 (en) * 2007-11-26 2010-09-08 Pfizer Inc. Pyrazole derivatives as 5-lo inhibitors
WO2013128378A1 (en) * 2012-02-28 2013-09-06 Piramal Enterprises Limited Phenyl alkanoic acid derivatives as gpr agonists
IL277071B1 (en) 2018-03-08 2024-03-01 Incyte Corp Aminopyrizine diol compounds as PI3K–y inhibitors
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0462830B1 (en) * 1990-06-21 1995-10-18 Zeneca Limited Cyclic ether derivatives
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
EP0505122A1 (en) * 1991-03-21 1992-09-23 Zeneca Limited Alpha, alpha-dialkylbenzyl derivatives
EP0540165A1 (en) * 1991-10-03 1993-05-05 Zeneca Limited Alkanoic acid derivatives
KR100190728B1 (ko) * 1993-06-14 1999-06-01 디. 제이. 우드, 스피겔 알렌 제이 이미다졸 리폭시게나제 저해제

Also Published As

Publication number Publication date
CN1169722A (zh) 1998-01-07
MY114680A (en) 2002-12-31
FI971632A0 (fi) 1997-04-17
SK128795A3 (en) 1996-07-03
EP0787127B1 (en) 2001-01-03
CZ287350B6 (en) 2000-10-11
LV11468B (en) 1996-12-20
DE69519804D1 (de) 2001-02-08
HU221543B (hu) 2002-11-28
CA2202057A1 (en) 1996-04-25
CO4480026A1 (es) 1997-07-09
FI971632A (fi) 1997-04-17
GR3035471T3 (en) 2001-05-31
TR199501274A2 (tr) 1996-06-21
HUT77363A (hu) 1998-03-30
ATE198474T1 (de) 2001-01-15
AU2417495A (en) 1996-05-06
CA2202057C (en) 2001-10-09
NO971773D0 (no) 1997-04-17
DE69519804T2 (de) 2001-04-19
NO314629B1 (no) 2003-04-22
IL115581A (en) 1999-10-28
YU65995A (sh) 1999-06-15
SK281577B6 (sk) 2001-05-10
PE49196A1 (es) 1996-11-21
SI9500392A (en) 1996-08-31
JP3032579B2 (ja) 2000-04-17
ZA958748B (en) 1997-04-17
TW411339B (en) 2000-11-11
BG61768B1 (bg) 1998-05-29
NO971773L (no) 1997-06-17
IL115581A0 (en) 1996-01-19
BG100070A (bg) 1996-05-31
NZ285163A (en) 1998-08-26
AU681520B2 (en) 1997-08-28
PL319727A1 (en) 1997-08-18
DK0787127T3 (da) 2001-02-05
UA45312C2 (uk) 2002-04-15
CZ117797A3 (cs) 1998-06-17
CN1093536C (zh) 2002-10-30
EP0787127A1 (en) 1997-08-06
ES2153033T3 (es) 2001-02-16
PL180104B1 (pl) 2000-12-29
RU2136666C1 (ru) 1999-09-10
WO1996011911A1 (en) 1996-04-25
JPH11507322A (ja) 1999-06-29

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