SI2424895T1 - Ingredients and procedures for increasing muscle growth - Google Patents
Ingredients and procedures for increasing muscle growth Download PDFInfo
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- SI2424895T1 SI2424895T1 SI201031603T SI201031603T SI2424895T1 SI 2424895 T1 SI2424895 T1 SI 2424895T1 SI 201031603 T SI201031603 T SI 201031603T SI 201031603 T SI201031603 T SI 201031603T SI 2424895 T1 SI2424895 T1 SI 2424895T1
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- 238000000034 method Methods 0.000 title claims 2
- 230000037257 muscle growth Effects 0.000 title claims 2
- 239000000203 mixture Substances 0.000 title 1
- 208000021642 Muscular disease Diseases 0.000 claims abstract 5
- 101100437153 Rattus norvegicus Acvr2b gene Proteins 0.000 claims abstract 5
- 201000000585 muscular atrophy Diseases 0.000 claims abstract 2
- 102000004169 proteins and genes Human genes 0.000 claims 16
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 claims 6
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 claims 6
- 108090001117 Insulin-Like Growth Factor II Proteins 0.000 claims 6
- 102000048143 Insulin-Like Growth Factor II Human genes 0.000 claims 6
- 239000000556 agonist Substances 0.000 claims 6
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- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
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- 206010028289 Muscle atrophy Diseases 0.000 abstract 1
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Classifications
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
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- Mycology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17300409P | 2009-04-27 | 2009-04-27 | |
| US30613710P | 2010-02-19 | 2010-02-19 | |
| PCT/EP2010/055458 WO2010125003A1 (en) | 2009-04-27 | 2010-04-23 | Compositions and methods for increasing muscle growth |
| EP10714332.3A EP2424895B1 (en) | 2009-04-27 | 2010-04-23 | Compositions and methods for increasing muscle growth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2424895T1 true SI2424895T1 (en) | 2018-01-31 |
Family
ID=42306628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201031603T SI2424895T1 (en) | 2009-04-27 | 2010-04-23 | Ingredients and procedures for increasing muscle growth |
Country Status (41)
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2561048T3 (es) * | 2004-07-23 | 2016-02-24 | Acceleron Pharma Inc. | Polipéptidos del receptor ActRII |
| EP1855694B1 (en) | 2005-02-09 | 2020-12-02 | Sarepta Therapeutics, Inc. | Antisense composition for treating muscle atrophy |
| US8128933B2 (en) * | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| EP3269381B1 (en) | 2005-11-23 | 2020-10-07 | Acceleron Pharma, Inc. | Activin-actriia antagonists in use for promoting bone growth |
| US20100028332A1 (en) * | 2006-12-18 | 2010-02-04 | Acceleron Pharma Inc. | Antagonists of actriib and uses for increasing red blood cell levels |
| US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
| CN103920139B (zh) | 2007-02-01 | 2018-02-02 | 阿塞勒隆制药公司 | 活化素‑actriia拮抗剂及在治疗或预防乳腺癌中的用途 |
| TW201907946A (zh) | 2007-02-02 | 2019-03-01 | 美商艾瑟勒朗法瑪公司 | 衍生自ＡｃｔＲＩＩＢ的變體與其用途 |
| CA2677605C (en) * | 2007-02-09 | 2016-01-19 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for promoting bone growth in cancer patients |
| TWI454479B (zh) | 2007-03-06 | 2014-10-01 | Amgen Inc | 變異之活動素受體多肽及其用途 |
| CN101861161B (zh) | 2007-09-18 | 2017-04-19 | 阿塞勒隆制药公司 | 活化素‑actriia拮抗剂和减少或抑制fsh分泌的用途 |
| US20100015144A1 (en) * | 2008-06-26 | 2010-01-21 | Acceleron Pharma Inc. | Methods for dosing an activin-actriia antagonist and monitoring of treated patients |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| PT3494986T (pt) | 2008-08-14 | 2020-07-14 | Acceleron Pharma Inc | Armadilhas para gdf |
| MY159483A (en) | 2008-11-26 | 2017-01-13 | Amgen Inc | Variants of activin iib receptor polypeptides and uses thereof |
| US8138142B2 (en) | 2009-01-13 | 2012-03-20 | Acceleron Pharma Inc. | Methods for increasing adiponectin in a patient in need thereof |
| EA201650137A1 (ru) * | 2009-04-27 | 2017-09-29 | Новартис Аг | Композиции и способы для усиления мышечного роста |
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