SI1928820T1 - Postopek za pripravo ester oksazolidin spojin in njihova pretvorba v florfenikol - Google Patents

Postopek za pripravo ester oksazolidin spojin in njihova pretvorba v florfenikol

Info

Publication number
SI1928820T1
SI1928820T1 SI200631769T SI200631769T SI1928820T1 SI 1928820 T1 SI1928820 T1 SI 1928820T1 SI 200631769 T SI200631769 T SI 200631769T SI 200631769 T SI200631769 T SI 200631769T SI 1928820 T1 SI1928820 T1 SI 1928820T1
Authority
SI
Slovenia
Prior art keywords
florfenicol
conversion
oxazolidine compounds
preparing ester
ester oxazolidine
Prior art date
Application number
SI200631769T
Other languages
English (en)
Inventor
James C. Towson
Original Assignee
Intervet International Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet International Bv filed Critical Intervet International Bv
Publication of SI1928820T1 publication Critical patent/SI1928820T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI200631769T 2005-09-07 2006-08-31 Postopek za pripravo ester oksazolidin spojin in njihova pretvorba v florfenikol SI1928820T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71468505P 2005-09-07 2005-09-07
PCT/US2006/034370 WO2007030405A2 (en) 2005-09-07 2006-08-31 A process for preparing ester oxazolidine compounds and their conversion to florfenicol
EP06824884.8A EP1928820B1 (en) 2005-09-07 2006-08-31 A process for preparing ester oxazolidine compounds and their conversion to florfenicol

Publications (1)

Publication Number Publication Date
SI1928820T1 true SI1928820T1 (sl) 2014-08-29

Family

ID=37684114

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631769T SI1928820T1 (sl) 2005-09-07 2006-08-31 Postopek za pripravo ester oksazolidin spojin in njihova pretvorba v florfenikol

Country Status (19)

Country Link
US (3) US20070055067A1 (sl)
EP (3) EP1934190A2 (sl)
JP (3) JP2009507074A (sl)
KR (3) KR20080049040A (sl)
CN (3) CN101300227B (sl)
AU (3) AU2006287697A1 (sl)
BR (3) BRPI0615565A2 (sl)
CA (3) CA2621971A1 (sl)
EC (3) ECSP088268A (sl)
ES (1) ES2459205T3 (sl)
IL (3) IL189830A0 (sl)
MX (3) MX2008003186A (sl)
NO (3) NO20081685L (sl)
RU (3) RU2008112952A (sl)
SI (1) SI1928820T1 (sl)
TW (3) TW200800924A (sl)
UA (1) UA93212C2 (sl)
WO (3) WO2007030385A2 (sl)
ZA (3) ZA200802048B (sl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050386A1 (es) 2003-05-29 2005-06-23 Schering Plough Ltd Composiciones farmaceuticas de florfenicol
EP1785414A1 (en) * 2005-11-09 2007-05-16 KRKA, tovarna zdravil, d.d., Novo mesto Process for the synthesis of intermediates of chloramphenicol or its analogues
CA2672795A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
CA2693922A1 (en) * 2007-07-25 2009-01-29 Intervet International B.V. Process for preparing oxazolidine-and oxazolidinone-aminodiols
PE20091171A1 (es) * 2007-12-14 2009-08-03 Schering Plough Ltd Proceso para recuperar florfenicol y analogos de florfenicol
JP2011529895A (ja) * 2008-07-30 2011-12-15 インターベツト・インターナシヨナル・ベー・ベー フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法
CN101941927B (zh) * 2010-09-28 2012-10-03 湖北美天生物科技有限公司 氟苯尼考中间体(1r,2r)-2-氨基-1–(4-(甲砜基)苯基)-1,3-丙二醇的合成方法
AU2012251438A1 (en) 2011-05-02 2013-11-14 Pfizer Inc. Novel cephalosporins useful as antibacterial agents
CN103254103A (zh) * 2013-06-05 2013-08-21 南通金利油脂工业有限公司 氟化剂在制备氟苯尼考工艺中的应用
CN103965085B (zh) * 2014-04-17 2016-02-24 上海恒晟药业有限公司 一种取代1,2-氨基醇药物的制备方法
CN106278964B (zh) * 2016-07-31 2018-01-16 浙江润康药业有限公司 氟苯尼考的制备方法
CN111500652B (zh) * 2019-01-30 2024-03-26 苏州引航生物科技有限公司 一种制备氟苯尼考的方法
CN110302163A (zh) * 2019-07-23 2019-10-08 东莞正大康地饲料有限公司 一种氟苯尼考可溶性粉及其制备方法
CN110773207A (zh) * 2019-09-25 2020-02-11 陈红菊 一种在室温且无光条件下可完全分解甲醛的冷触媒材料及其制备方法
CN111423391A (zh) * 2020-03-18 2020-07-17 浙江康牧药业有限公司 一种氟苯尼考中间体的制备方法
CN113402475A (zh) * 2021-06-07 2021-09-17 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002637A (en) * 1973-07-09 1977-01-11 Rohm And Haas Company Oxazolidine, oxazolidine-containing condensation and addition polymers and methods of producing them
EP0677511A3 (en) * 1983-06-02 1996-07-24 Zambon Spa Intermediates for the production of 1-phenyl-1-hydroxy-2-amino-3-fluoropropane derivatives.
IT1237798B (it) * 1989-10-20 1993-06-17 Zambon Spa Processo per l'inversione stereochimica di (2s,3s)-2-ammino-3-fenil-1 ,3-propandioli nei corrispondenti enantiomeri (2r,3r).
WO1994004523A1 (en) * 1992-08-21 1994-03-03 Japan Tobacco Inc. Dioxacycloalkane compound with renin-inhibiting activity
US5663361A (en) * 1996-08-19 1997-09-02 Schering Corporation Process for preparing intermediates to florfenicol
JP2001240571A (ja) * 2000-03-01 2001-09-04 Udagawa Reiko フッ素アルコールの製造方法
TW200406372A (en) 2002-03-08 2004-05-01 Schering Plough Ltd Novel florfenicol-type antibiotics
US7126005B2 (en) * 2003-10-06 2006-10-24 Aurobindo Pharma Limited Process for preparing florfenicol

Also Published As

Publication number Publication date
UA93212C2 (ru) 2011-01-25
NO20081686L (no) 2008-06-05
EP1934190A2 (en) 2008-06-25
JP2009507074A (ja) 2009-02-19
NO20081684L (no) 2008-06-05
MX2008003186A (es) 2008-03-18
BRPI0615565A2 (pt) 2011-05-24
EP1934189A2 (en) 2008-06-25
US20070055067A1 (en) 2007-03-08
ECSP088266A (es) 2008-04-28
RU2008112946A (ru) 2009-10-20
CN101300238A (zh) 2008-11-05
BRPI0615767A2 (pt) 2011-05-24
WO2007030385A2 (en) 2007-03-15
KR20080049040A (ko) 2008-06-03
EP1928820A2 (en) 2008-06-11
ZA200802047B (en) 2008-12-31
TW200800924A (en) 2008-01-01
ECSP088268A (es) 2008-04-28
US20070055080A1 (en) 2007-03-08
WO2007030385A3 (en) 2007-05-24
JP2009507075A (ja) 2009-02-19
AU2006287697A1 (en) 2007-03-15
JP2009507842A (ja) 2009-02-26
TW200804254A (en) 2008-01-16
NO20081685L (no) 2008-06-05
JP5113754B2 (ja) 2013-01-09
CN101300227B (zh) 2013-07-03
ZA200802048B (en) 2008-11-26
US20070055066A1 (en) 2007-03-08
BRPI0615764A2 (pt) 2011-05-24
IL189828A0 (en) 2008-11-03
KR20080049039A (ko) 2008-06-03
RU2008112952A (ru) 2009-10-20
KR20080041699A (ko) 2008-05-13
AU2006287716A1 (en) 2007-03-15
AU2006287696A1 (en) 2007-03-15
KR101408596B1 (ko) 2014-06-17
ECSP088267A (es) 2008-04-28
IL189829A0 (en) 2008-11-03
CN101300227A (zh) 2008-11-05
RU2008112950A (ru) 2009-10-20
MX2008003188A (es) 2008-03-18
WO2007030386A2 (en) 2007-03-15
US7786329B2 (en) 2010-08-31
IL189830A0 (en) 2008-11-03
MX2008003187A (es) 2008-03-18
WO2007030405A2 (en) 2007-03-15
TWI331139B (en) 2010-10-01
CA2621987A1 (en) 2007-03-15
ES2459205T3 (es) 2014-05-08
TW200804253A (en) 2008-01-16
CA2621961A1 (en) 2007-03-15
WO2007030386A3 (en) 2007-05-24
WO2007030405A3 (en) 2007-05-18
CA2621971A1 (en) 2007-03-15
ZA200802046B (en) 2008-12-31
EP1928820B1 (en) 2014-01-29
CN101300237A (zh) 2008-11-05

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