SG156641A1 - Compounds for nonsense suppression, and methods for their use - Google Patents
Compounds for nonsense suppression, and methods for their useInfo
- Publication number
- SG156641A1 SG156641A1 SG200906829-7A SG2009068297A SG156641A1 SG 156641 A1 SG156641 A1 SG 156641A1 SG 2009068297 A SG2009068297 A SG 2009068297A SG 156641 A1 SG156641 A1 SG 156641A1
- Authority
- SG
- Singapore
- Prior art keywords
- compounds
- methods
- compositions
- present
- nonsense suppression
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000001629 suppression Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 108020004485 Nonsense Codon Proteins 0.000 abstract 2
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 230000037434 nonsense mutation Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002028 premature Effects 0.000 abstract 1
Classifications
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- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- 2014-04-28 US US14/263,478 patent/US9273076B2/en not_active Expired - Lifetime
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2015
- 2015-06-08 US US14/733,615 patent/US20150274674A1/en not_active Abandoned
-
2016
- 2016-04-15 US US15/130,318 patent/US20160229818A1/en not_active Abandoned
-
2017
- 2017-03-31 US US15/475,240 patent/US20170204073A1/en not_active Abandoned
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