SG11201406112TA - Improved harvest operations for recombinant proteins - Google Patents

Improved harvest operations for recombinant proteins

Info

Publication number
SG11201406112TA
SG11201406112TA SG11201406112TA SG11201406112TA SG11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA SG 11201406112T A SG11201406112T A SG 11201406112TA
Authority
SG
Singapore
Prior art keywords
recombinant proteins
harvest operations
improved harvest
improved
operations
Prior art date
Application number
SG11201406112TA
Other languages
English (en)
Inventor
Michael W Laird
John Richard St
Jane V Gunson
Kim Kaleas
Deepa Nadarajah
Rachel Adams
Bradley R Snedecor
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG11201406112TA publication Critical patent/SG11201406112TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/42Means for regulation, monitoring, measurement or control, e.g. flow regulation of agitation speed
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201406112TA 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins SG11201406112TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261616297P 2012-03-27 2012-03-27
PCT/US2013/031383 WO2013148249A1 (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Publications (1)

Publication Number Publication Date
SG11201406112TA true SG11201406112TA (en) 2014-10-30

Family

ID=48040433

Family Applications (4)

Application Number Title Priority Date Filing Date
SG10201508420VA SG10201508420VA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG10201912877SA SG10201912877SA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG10202007206WA SG10202007206WA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG11201406112TA SG11201406112TA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Family Applications Before (3)

Application Number Title Priority Date Filing Date
SG10201508420VA SG10201508420VA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG10201912877SA SG10201912877SA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
SG10202007206WA SG10202007206WA (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Country Status (20)

Country Link
US (9) US20140080180A1 (enExample)
EP (1) EP2831261B1 (enExample)
JP (4) JP6225162B2 (enExample)
KR (2) KR102096678B1 (enExample)
CN (2) CN104350156B (enExample)
AR (2) AR090340A1 (enExample)
AU (3) AU2013240280A1 (enExample)
BR (1) BR112014023176B1 (enExample)
CA (2) CA2866753C (enExample)
ES (1) ES2654424T3 (enExample)
HR (1) HRP20171966T1 (enExample)
IL (1) IL234377B (enExample)
MX (3) MX365947B (enExample)
MY (1) MY171729A (enExample)
PL (1) PL2831261T3 (enExample)
RU (2) RU2636353C2 (enExample)
SG (4) SG10201508420VA (enExample)
SI (1) SI2831261T1 (enExample)
WO (1) WO2013148249A1 (enExample)
ZA (1) ZA201406434B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201037B1 (en) 1986-01-28 2001-03-13 Ophthalmic Research Group International, Inc. Plastic lens composition and method for the production thereof
CA3026589A1 (en) 2016-06-10 2017-12-14 Lonza Ltd Method for stabilizing proteins
US10828375B2 (en) * 2016-11-07 2020-11-10 Seattle Genetics, Inc. Distribution of engineered-cysteine caps
CN120943884A (zh) * 2018-03-27 2025-11-14 百时美施贵宝公司 使用紫外线信号实时监测滴度
CN117110492A (zh) * 2019-01-16 2023-11-24 瑞泽恩制药公司 鉴别蛋白质中的游离巯基的方法
CN109725088B (zh) * 2019-03-16 2021-05-18 丁立平 一种测定豆芽中2-萘甲酸及其衍生物的气相色谱-质谱联用法
CN110305903B (zh) * 2019-07-31 2021-10-01 江苏璟泽生物医药有限公司 重组人促卵泡激素及其制备方法
CN113155776A (zh) * 2021-04-29 2021-07-23 华东交通大学 一种柑桔最佳采收期预测方法
FR3146146A1 (fr) 2023-02-24 2024-08-30 Bgene Genetics Production d’acide 1-4-dihydroxy-2-naphtoïque par Escherichia coli

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2036891B (en) 1978-12-05 1983-05-05 Windsor Smith C Change speed gear
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5672347A (en) 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
EP0247091B1 (en) 1985-11-01 1993-09-29 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
EP0420937B1 (en) 1988-06-21 1994-11-09 Genentech, Inc. Therapeutic compositions for the treatment of myocardial infarction
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
EP1260521B1 (en) 1991-08-14 2007-11-21 Genentech Inc. Immunoglobulin variants for specific Fc epsilon receptors
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
US5288931A (en) 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
CA2140280A1 (en) 1992-08-17 1994-03-03 Avi J. Ashkenazi Bispecific immunoadhesins
ATE161192T1 (de) 1992-08-21 1998-01-15 Genentech Inc Verfahren zur behandlung einer durch lfa-1 vermittelten störung
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
ES2108566T3 (es) 1993-12-10 1997-12-16 Genentech Inc Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos.
ATE164079T1 (de) 1994-01-18 1998-04-15 Genentech Inc Verfahren zur behandlung von parasitären infektionen unter verwendung von ige-antagonisten
US5707622A (en) 1994-03-03 1998-01-13 Genentech, Inc. Methods for treating ulcerative colitis
US5639635A (en) 1994-11-03 1997-06-17 Genentech, Inc. Process for bacterial production of polypeptides
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
WO1996040210A1 (en) 1995-06-07 1996-12-19 Imclone Systems Incorporated Antibody and antibody fragments for inhibiting the growth of tumors
EP1297847A3 (en) 1996-01-23 2003-05-07 Genentech, Inc. Anti-CD18 antibodies in stroke
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
ATE267257T1 (de) 1996-11-27 2004-06-15 Genentech Inc Humanisierte anti-koerper gegen cd11a
ES2273415T3 (es) 1997-04-07 2007-05-01 Genentech, Inc. Anticuerpos anti-vegf.
ATE516354T1 (de) 1997-05-15 2011-07-15 Genentech Inc Apo-2-rezeptor
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
CA2387108A1 (en) 1999-10-29 2001-06-07 Genentech, Inc. Anti-prostate stem cell antigen (psca) antibody compositions and methods of use
US6946271B2 (en) * 2000-09-20 2005-09-20 Degussa Ag Nucleotide sequences which code for the menE gene
US6979556B2 (en) 2000-12-14 2005-12-27 Genentech, Inc. Separate-cistron contructs for secretion of aglycosylated antibodies from prokaryotes
AR042485A1 (es) 2002-12-16 2005-06-22 Genentech Inc Anticuerpo humanizado que se une al cd20 humano
US8277860B2 (en) * 2003-03-26 2012-10-02 Meiji Co., Ltd. Method of stabilizing 1,4-dihydroxy-2-naphthoic acid
EP1656452B1 (en) * 2003-08-13 2007-02-14 Sandoz AG Expression vectors, transformed host cells and fermentation process for the production of recombinant polypeptides
US7998732B2 (en) * 2004-02-04 2011-08-16 Merck Sharp & Dohme Corp. Process for large scale production of plasmid DNA by E. coli fermentation
US7361764B2 (en) * 2004-07-27 2008-04-22 Sgx Pharmaceuticals, Inc. Pyrrolo-pyridine kinase modulators
CN101115832A (zh) * 2004-11-26 2008-01-30 协和发酵工业株式会社 工业上有用的微生物
MX2008014150A (es) * 2006-05-05 2009-02-04 Gangagen Inc Actividades antimicrobianas derivadas de fago.
JP5305615B2 (ja) * 2006-06-05 2013-10-02 株式会社Adeka メナキノンの新規生合成経路に関与するタンパク質の遺伝子群を利用したメナキノンの製造方法
KR101520105B1 (ko) * 2006-07-14 2015-05-21 제넨테크, 인크. 재조합 단백질의 리폴딩
HUE046992T2 (hu) * 2007-07-09 2020-04-28 Genentech Inc Diszulfidkötés redukciójának megelõzése polipeptidek rekombináns elõállítása során
CN101665798B (zh) * 2008-09-06 2012-11-21 浙江我武生物科技股份有限公司 一种制备重组人血清白蛋白与干扰素α融合蛋白的方法
CN101503470A (zh) * 2008-09-27 2009-08-12 上海交通大学 rhDSL重组蛋白及其制备方法
JP2010088387A (ja) * 2008-10-10 2010-04-22 Waseda Univ 放線菌内で目的タンパク質を誘導発現可能なプロモーター

Also Published As

Publication number Publication date
EP2831261A1 (en) 2015-02-04
US20140080180A1 (en) 2014-03-20
PL2831261T3 (pl) 2018-04-30
US20250137027A1 (en) 2025-05-01
CN109880867A (zh) 2019-06-14
SG10202007206WA (en) 2020-08-28
MY171729A (en) 2019-10-25
IL234377B (en) 2021-01-31
ZA201406434B (en) 2017-08-30
JP6225162B2 (ja) 2017-11-01
CN104350156B (zh) 2019-04-02
RU2017139267A (ru) 2019-02-12
SG10201912877SA (en) 2020-02-27
JP2019141049A (ja) 2019-08-29
HRP20171966T1 (hr) 2018-02-09
AU2017202484A1 (en) 2017-05-04
MX365947B (es) 2019-06-19
ES2654424T3 (es) 2018-02-13
JP2015512259A (ja) 2015-04-27
JP2018046825A (ja) 2018-03-29
WO2013148249A1 (en) 2013-10-03
KR102096678B1 (ko) 2020-04-02
AR090340A1 (es) 2014-11-05
JP2020202849A (ja) 2020-12-24
AR116615A2 (es) 2021-05-26
CA2866753A1 (en) 2013-10-03
US9765379B2 (en) 2017-09-19
MX2018007677A (es) 2020-11-12
US20180291411A1 (en) 2018-10-11
BR112014023176B1 (pt) 2021-09-28
KR20140148392A (ko) 2014-12-31
US20230069966A1 (en) 2023-03-09
HK1207120A1 (en) 2016-01-22
US20160130624A1 (en) 2016-05-12
RU2636353C2 (ru) 2017-11-22
MX2019007032A (es) 2019-08-16
CN104350156A (zh) 2015-02-11
BR112014023176A2 (pt) 2017-06-20
US20240158825A1 (en) 2024-05-16
MX2014011558A (es) 2014-11-14
SI2831261T1 (en) 2018-01-31
AU2019226192A1 (en) 2019-09-26
RU2014137554A (ru) 2016-05-20
CA2866753C (en) 2020-09-22
US20210171997A1 (en) 2021-06-10
US20200199639A1 (en) 2020-06-25
KR20200037425A (ko) 2020-04-08
AU2013240280A1 (en) 2014-10-16
US20150225760A1 (en) 2015-08-13
AU2017202484B2 (en) 2019-06-13
CA3086730A1 (en) 2013-10-03
EP2831261B1 (en) 2017-10-18
SG10201508420VA (en) 2015-11-27

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