ES2108566T3 - Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos. - Google Patents

Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos.

Info

Publication number
ES2108566T3
ES2108566T3 ES95905357T ES95905357T ES2108566T3 ES 2108566 T3 ES2108566 T3 ES 2108566T3 ES 95905357 T ES95905357 T ES 95905357T ES 95905357 T ES95905357 T ES 95905357T ES 2108566 T3 ES2108566 T3 ES 2108566T3
Authority
ES
Spain
Prior art keywords
patient serum
allergen
pct
host cells
ige
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95905357T
Other languages
English (en)
Inventor
Wai Fei David Tai
John Lowe
Paula Jardieu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2108566T3 publication Critical patent/ES2108566T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins

Abstract

SE PROPORCIONAN TAMBIEN METODOS PARA DIAGNOSTICO DE UNA ENFERMEDAD ALERGICA EN UN PACIENTE. SE PROPORCIONAN TAMBIEN METODOS DE INVESTIGACION DE PRODUCTOS TERAPEUTICOS ANTI-ALERGICOS Y ANTAGONISTAS IGE.
ES95905357T 1993-12-10 1994-12-09 Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos. Expired - Lifetime ES2108566T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16543693A 1993-12-10 1993-12-10

Publications (1)

Publication Number Publication Date
ES2108566T3 true ES2108566T3 (es) 1997-12-16

Family

ID=22598886

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95905357T Expired - Lifetime ES2108566T3 (es) 1993-12-10 1994-12-09 Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos.

Country Status (10)

Country Link
US (1) US5714338A (es)
EP (1) EP0733207B1 (es)
JP (1) JP3507852B2 (es)
AT (1) ATE157455T1 (es)
CA (1) CA2176811C (es)
DE (1) DE69405251T2 (es)
DK (1) DK0733207T3 (es)
ES (1) ES2108566T3 (es)
GR (1) GR3025089T3 (es)
WO (1) WO1995016203A2 (es)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9526599D0 (en) * 1995-12-28 1996-02-28 Sandoz Ltd Elisa test system
DE19643427C1 (de) * 1996-10-22 1998-02-12 Bundesrep Deutschland Verfahren zur Bestimmung von Allergenen in der Luft
US6165799A (en) * 1996-12-10 2000-12-26 Heska Corporation Detection of anti-Fc.sub.ε R autoantibodies in asthmatics
US7122636B1 (en) * 1997-02-21 2006-10-17 Genentech, Inc. Antibody fragment-polymer conjugates and uses of same
US6060326A (en) * 1997-04-07 2000-05-09 Heska Corporation Method to detect canine IgE and kit therefor
FR2765341A1 (fr) * 1997-06-25 1998-12-31 Alain Funes Methode pour l'analyse de l'activation des basophiles humains par mesure de l'expression membranaire du marqueur cd63
WO2000029431A1 (en) * 1998-11-17 2000-05-25 Tanox, Inc. Bispecific molecules cross-linking itim and itam for therapy
WO2001051076A1 (en) * 2000-01-14 2001-07-19 Tanox, Inc. ADMINISTERING IgE ANTAGONISTS DURING PREGNANCY TO AMELIORATE ALLERGIC DISEASES IN THE OFFSPRING
US6889145B1 (en) 2000-03-15 2005-05-03 Northwestern University Three-dimensional model of a Fc region of an IgE antibody and uses thereof
EP1195606A1 (en) * 2000-10-03 2002-04-10 VBC-Genomics Forschungsges.m.b.H. Allergen-microarray assay
DE10110838C2 (de) * 2001-03-06 2003-04-03 Mlu Halle Wittenberg Verfahren zur Diagnostik von Allergien, Pseudoallergien und Intoleranzen
FR2831186B1 (fr) * 2001-10-22 2004-06-18 Aventis Pharma Sa Production d'heparine a partir de cultures de mastocytes
WO2003066662A2 (en) 2002-02-05 2003-08-14 Genentech, Inc. Protein purification
US7323553B2 (en) 2002-04-26 2008-01-29 Genentech, Inc. Non-affinity purification of proteins
EP3095793B1 (en) 2003-07-28 2020-03-25 Genentech, Inc. Reducing protein a leaching during protein a affinity chromatography
US7613619B1 (en) * 2004-03-30 2009-11-03 Harter Michael R Method for identifying allergens and other influencing agents that may cause a reaction
US7662926B2 (en) * 2004-09-02 2010-02-16 Genentech, Inc. Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
US7655229B2 (en) * 2004-09-02 2010-02-02 Chan Andrew C Anti-FC-gamma RIIB receptor antibody and uses therefor
AU2005282720B2 (en) * 2004-09-02 2011-08-04 Genentech, Inc. Anti-FC-gamma RIIB receptor antibody and uses therefor
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
DK1861705T3 (da) * 2005-03-16 2011-05-23 Nutricia Nv Fremgangsmåde til at bestemme allergisk respons
EP1913393A4 (en) * 2005-06-16 2010-03-03 Univ California PARALLEL ALLERGIESTEST IMMUNA BASEBALL AND DEVICE FOR FLUORESCENT EXCITING WITH EVANESCENCE FIELD
US20080011058A1 (en) * 2006-03-20 2008-01-17 The Regents Of The University Of California Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
AU2007327150B2 (en) * 2006-12-01 2012-07-12 Statens Serum Institut Screening method using sample adsorption on filter paper
US8163886B2 (en) * 2006-12-21 2012-04-24 Emd Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
ES2426158T3 (es) 2007-01-22 2013-10-21 Genentech, Inc. Precipitación con polielectrolito y purificación de anticuerpos
US8191403B2 (en) * 2007-03-27 2012-06-05 Richmond Chemical Corporation Petroleum viscosity measurement and communication system and method
JP5687057B2 (ja) 2007-07-09 2015-03-18 ジェネンテック， インコーポレイテッド ポリペプチドの組換え生産中におけるジスルフィド結合還元の防止
KR20140015166A (ko) 2007-10-30 2014-02-06 제넨테크, 인크. 양이온 교환 크로마토그래피에 의한 항체 정제
WO2009151514A1 (en) * 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
ES2749190T3 (es) 2008-08-14 2020-03-19 Genentech Inc Métodos para eliminar un contaminante usando cromatografía de membrana de intercambio iónico de desplazamiento de proteínas indígenas
MX2011002372A (es) 2008-09-10 2011-04-04 Genentech Inc Composiciones y metodos para la prevencion de la degradacion oxidativa de proteinas.
EP2370561B1 (en) 2008-12-16 2019-08-07 EMD Millipore Corporation Stirred tank reactor and method
US20110020327A1 (en) * 2008-12-16 2011-01-27 Millipore Corporation Purification of proteins
SG173812A1 (en) 2009-02-27 2011-09-29 Genentech Inc Methods and compositions for protein labelling
US10184937B2 (en) * 2009-03-31 2019-01-22 United Arab Emirates University Minimally invasive assessment of IgE mediated allergy
DE102009030845A1 (de) * 2009-06-26 2010-12-30 Siemens Aktiengesellschaft Verfahren und Kit zur Diagnose oder Prognose einer Kontrastmittelallergie
KR101822205B1 (ko) 2009-08-11 2018-01-25 제넨테크, 인크. 글루타민-비함유 세포 배양 배지에서의 단백질의 생성
ES2787234T3 (es) 2009-09-01 2020-10-15 Hoffmann La Roche Purificación de proteínas potenciada a través de una elución de proteína A modificada
MX354867B (es) 2010-03-22 2018-03-23 Genentech Inc Star Composiciones y métodos útiles para estabilizar formulaciones que contienen proteína.
JP2013525484A (ja) 2010-05-03 2013-06-20 ジェネンテック， インコーポレイテッド タンパク質含有製剤の粘度を低減させるために有用な組成物及び方法
ES2754210T3 (es) 2010-05-17 2020-04-16 Emd Millipore Corp Polímeros sensibles a estímulos para la purificación de biomoléculas
KR20190067277A (ko) 2010-05-28 2019-06-14 제넨테크, 인크. 락테이트 데히드로게나제 및 피루베이트 데히드로게나제 키나제의 발현의 하향조절에 의한 락테이트 수준의 감소 및 폴리펩티드 생산의 증가
CA2802756C (en) 2010-06-24 2021-05-04 Genentech, Inc. Compositions and methods for stabilizing protein-containing formulations
EP2603525A1 (en) 2010-08-13 2013-06-19 F.Hoffmann-La Roche Ag Antibodies to il-1beta and il-18, for treatment of disease
WO2012030512A1 (en) 2010-09-03 2012-03-08 Percivia Llc. Flow-through protein purification process
WO2013009491A2 (en) 2011-07-08 2013-01-17 Nripen Singh Improved depth filters for disposable biotechnological processes
AU2012355356B2 (en) 2011-12-22 2017-10-12 Genentech, Inc. Ion exchange membrane chromatography
SG10202007206WA (en) 2012-03-27 2020-08-28 Genentech Inc Improved harvest operations for recombinant proteins
EP3427721A1 (en) 2012-05-18 2019-01-16 Genentech, Inc. High-concentration monoclonal antibody formulations
EP2934602B1 (en) 2012-12-19 2019-02-27 Genentech, Inc. Methods and compositions for radiohalogen protein labeling
SG11201700097WA (en) 2014-07-09 2017-02-27 Genentech Inc Ph adjustment to improve thaw recovery of cell banks
EP3436610A1 (en) 2016-03-29 2019-02-06 Geltor, Inc. Expression of proteins in gram-negative bacteria wherein the ratio of periplasmic volume to cytoplasmic volume is between 0.5:1 and 10:1
MX2019007433A (es) 2016-12-22 2019-08-16 Genentech Inc Metodos y formulaciones para reducir el tiempo de reconstitucion de los polipeptidos liofilizados.
US11180541B2 (en) 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
BR112020025623A2 (pt) 2018-07-03 2021-03-23 Bristol-Myers Squibb Company métodos de produção de proteínas recombinantes
EP3864127A1 (en) 2018-10-10 2021-08-18 Boehringer Ingelheim International GmbH Method for membrane gas transfer in high density bioreactor culture
TW202102266A (zh) 2019-04-01 2021-01-16 美商建南德克公司 用於穩定含有蛋白質之配方之組合物及方法
JP2022526434A (ja) 2019-04-12 2022-05-24 ジェルター， インコーポレイテッド 組換えエラスチンおよびその産生
JP2022543781A (ja) 2019-08-01 2022-10-14 ブリストル－マイヤーズ スクイブ カンパニー フェッドバッチ細胞培養におけるタンパク質産生性の改良方法
KR20230073270A (ko) 2020-09-22 2023-05-25 브리스톨-마이어스 스큅 컴퍼니 치료 단백질의 생산 방법
CN113495139A (zh) * 2021-07-07 2021-10-12 上海清芮科技有限公司 一种宠物特应性体质的检测方法
WO2023015234A1 (en) 2021-08-05 2023-02-09 Bristol-Myers Squibb Company Cell culture methods for producing therapeutic proteins
WO2023049687A1 (en) 2021-09-21 2023-03-30 Bristol-Myers Squibb Company Methods of controlling the level of dissolved oxygen (do) in a solution comprising a recombinant protein in a storage container

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559310A (en) * 1983-05-20 1985-12-17 Dana Farber Cancer Institute Assay methods and systems utilizing mast cell clones
US4946788A (en) * 1985-06-11 1990-08-07 Ciba-Geigy Corporation Purified immunoglobulin-related factor, novel monoclonal antibodies, hybridoma cell lines, processes and applications
EP0248211B1 (en) * 1986-04-30 1992-03-11 Junji Yodoi Novel protein and a method for production thereof
US5180805A (en) * 1986-07-02 1993-01-19 Research Corporation Limited Polypeptide competitor for immunoglobulin E
GB8727045D0 (en) * 1987-11-19 1987-12-23 Research Corp Ltd Immunoglobulin e competitor
US4962035A (en) * 1987-12-01 1990-10-09 President And Fellows Of Harvard College DNA encoding IgE receptor alpha-subunit or fragment thereof
JPH03127997A (ja) * 1989-10-11 1991-05-31 Kuraray Co Ltd ヒト１ｇＥ結合因子に特異的なモノクローン抗体、それを産生するハイブリドーマおよびその用途
CA2059842A1 (en) * 1991-02-11 1992-08-12 Richard A. Chizzonite Ige-receptor-antibodies
WO1993011437A1 (en) * 1991-12-05 1993-06-10 Board Of Regents Of The University Of Nebraska Allergen specific immunoglobulin-e producer test for diagnosing allergies
GB9224956D0 (en) * 1992-11-28 1993-01-20 Euro Dpc Ltd Improvements relating to allergen testing & apparatus

Also Published As

Publication number Publication date
DE69405251D1 (de) 1997-10-02
ATE157455T1 (de) 1997-09-15
EP0733207B1 (en) 1997-08-27
CA2176811C (en) 2008-01-29
WO1995016203A2 (en) 1995-06-15
GR3025089T3 (en) 1998-01-30
CA2176811A1 (en) 1995-06-15
JP3507852B2 (ja) 2004-03-15
EP0733207A1 (en) 1996-09-25
DE69405251T2 (de) 1998-02-05
DK0733207T3 (da) 1998-04-20
WO1995016203A3 (en) 1995-06-29
JPH09506435A (ja) 1997-06-24
US5714338A (en) 1998-02-03

Similar Documents

Publication Publication Date Title
ES2108566T3 (es) Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos.
Nelson et al. Evaluation of devices for skin prick testing
Beeler et al. CD69 upregulation on T cells as an in vitro marker for delayed‐type drug hypersensitivity
Popple et al. The lymphocyte transformation test in allergic contact dermatitis: new opportunities
Moore et al. Smartphone-based measurement of executive function in older adults with and without HIV
Fourie et al. Vascular function and cardiovascular risk in a HIV infected and HIV free cohort of African ancestry: Baseline profile, rationale and methods of the longitudinal EndoAfrica-NWU study
Al-Shammari et al. Quality of life in vitiligo patients in central Saudi Arabia
Choquet-Kastylevsky et al. Drug allergy diagnosis in humans: possibilities and pitfalls
Lushington et al. Are counseling students stressed? A cross-cultural comparison of burnout in Australian, Singaporean and Hong Kong counseling students
Hogrefe Biomarkers and assessment of vaccine responses
Smits et al. Evaluating the response of patients undergoing both allergy skin testing and in vitro allergy testing with the ImmunoCAP Technology System
Fitzpatrick et al. Health care needs of Indochinese refugee teenagers
YOSHIMURA et al. Diagnosis of drug allergy by the lymphocyte stimulation test with the MTT [3-(4, 5-dimethyl thiazol-2-yl)-2, 5-diphenyl tetrazolium bromide] assay
Yarube et al. Impaired cognition and normal cardiometabolic parameters in patients with type 2 diabetes in Kano, Nigeria
Chirumbolo CD164 and other recently discovered activation markers as promising tools for allergy diagnosis: what’s new?
SE9501782D0 (sv) Method of predicting the therapeutic response of a drug against a malignant tumour
Grobusch et al. Sensitivity of P. vivax rapid antigen detection tests and possible implications for self-diagnostic use
Dvorak et al. Diamine oxidase-gold ultrastructural localization of histamine in human skin biopsies containing mast cells stimulated to degranulate in vivo by exposure to recombinant human stem cell factor
Barnes Keeping the AIDS Virus Out of Blood Supply: More accurate blood tests are needed, according to an NIH consensus panel
Zevon et al. Stress and coping relationships in the medical environment: A natural experiment
Goldberg et al. A Novel System to Diagnose Cutaneous Adverse Drug Reactions Employing the Cellscan—Comparison with Histamine Releasing Test and Inf-γ Releasing Test
John et al. Nerve Conduction Study in Children with Insulin Dependent Diabetes Mellitus
Braver The attachment dimension in schizophrenia.
Kuczynski The holistic health care of couples undergoing IVF/ET.
Matarazzo et al. APA and AIDS: The evolution of a scientific and professional initiative in the public interest.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 733207

Country of ref document: ES