DE69405251D1 - Methoden zur diagnose von allergie und prüfung anti-allergischer therapeutika - Google Patents

Methoden zur diagnose von allergie und prüfung anti-allergischer therapeutika

Info

Publication number
DE69405251D1
DE69405251D1 DE69405251T DE69405251T DE69405251D1 DE 69405251 D1 DE69405251 D1 DE 69405251D1 DE 69405251 T DE69405251 T DE 69405251T DE 69405251 T DE69405251 T DE 69405251T DE 69405251 D1 DE69405251 D1 DE 69405251D1
Authority
DE
Germany
Prior art keywords
patient serum
allergen
pct
host cells
ige
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69405251T
Other languages
English (en)
Other versions
DE69405251T2 (de
Inventor
Wai Fei David Tai
John Lowe
Paula Jardieu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DE69405251D1 publication Critical patent/DE69405251D1/de
Application granted granted Critical
Publication of DE69405251T2 publication Critical patent/DE69405251T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
DE69405251T 1993-12-10 1994-12-09 Methoden zur diagnose von allergie und prüfung anti-allergischer therapeutika Expired - Lifetime DE69405251T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16543693A 1993-12-10 1993-12-10
PCT/US1994/014282 WO1995016203A2 (en) 1993-12-10 1994-12-09 Methods for diagnosis of allergy and screening of anti-allergy therapeutics

Publications (2)

Publication Number Publication Date
DE69405251D1 true DE69405251D1 (de) 1997-10-02
DE69405251T2 DE69405251T2 (de) 1998-02-05

Family

ID=22598886

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69405251T Expired - Lifetime DE69405251T2 (de) 1993-12-10 1994-12-09 Methoden zur diagnose von allergie und prüfung anti-allergischer therapeutika

Country Status (10)

Country Link
US (1) US5714338A (de)
EP (1) EP0733207B1 (de)
JP (1) JP3507852B2 (de)
AT (1) ATE157455T1 (de)
CA (1) CA2176811C (de)
DE (1) DE69405251T2 (de)
DK (1) DK0733207T3 (de)
ES (1) ES2108566T3 (de)
GR (1) GR3025089T3 (de)
WO (1) WO1995016203A2 (de)

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US6889145B1 (en) 2000-03-15 2005-05-03 Northwestern University Three-dimensional model of a Fc region of an IgE antibody and uses thereof
EP1195606A1 (de) * 2000-10-03 2002-04-10 VBC-Genomics Forschungsges.m.b.H. Allergen-Assay auf Basis von Mikroanordnungen
DE10110838C2 (de) * 2001-03-06 2003-04-03 Mlu Halle Wittenberg Verfahren zur Diagnostik von Allergien, Pseudoallergien und Intoleranzen
FR2831186B1 (fr) * 2001-10-22 2004-06-18 Aventis Pharma Sa Production d'heparine a partir de cultures de mastocytes
US6870034B2 (en) 2002-02-05 2005-03-22 Genentech, Inc. Protein purification
JP4319979B2 (ja) 2002-04-26 2009-08-26 ジェネンテック・インコーポレーテッド タンパク質の非アフィニティ精製
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US7613619B1 (en) * 2004-03-30 2009-11-03 Harter Michael R Method for identifying allergens and other influencing agents that may cause a reaction
US7655229B2 (en) * 2004-09-02 2010-02-02 Chan Andrew C Anti-FC-gamma RIIB receptor antibody and uses therefor
WO2006028956A2 (en) * 2004-09-02 2006-03-16 Genentech, Inc. Anti-fc-gamma riib receptor antibody and uses therefor
US7662926B2 (en) * 2004-09-02 2010-02-16 Genentech, Inc. Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
ATE505728T1 (de) * 2005-03-16 2011-04-15 Nutricia Nv Verfahren zur bestimmung einer allergischen reaktion
US20070117217A1 (en) * 2005-06-16 2007-05-24 The Regents Of The University Of California Large scale parallel immuno-based allergy test and device for evanescent field excitation of fluorescence
US20080011058A1 (en) * 2006-03-20 2008-01-17 The Regents Of The University Of California Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
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US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
WO2008079280A1 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
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WO2008091740A2 (en) 2007-01-22 2008-07-31 Genentech, Inc. Polyelectrolyte precipitation and purification of antibodies
US8191403B2 (en) * 2007-03-27 2012-06-05 Richmond Chemical Corporation Petroleum viscosity measurement and communication system and method
EP2188302B1 (de) 2007-07-09 2017-11-01 Genentech, Inc. Verhinderung der reduktion der disulfidbindung während der rekombinanten herstellung von polypeptiden
EP2840090B1 (de) 2007-10-30 2018-02-21 Genentech, Inc. Antikörperaufreinigung durch Kationen-Austausch-Chromatographie
US8999702B2 (en) * 2008-06-11 2015-04-07 Emd Millipore Corporation Stirred tank bioreactor
AU2008360625C1 (en) 2008-08-14 2017-01-19 Genentech, Inc. Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography
EP2684570A1 (de) 2008-09-10 2014-01-15 F. Hoffmann-La Roche AG Zusammensetzungen und Verfahren zur Prävention des oxidativen Abbaus von Proteinen
US20110020327A1 (en) * 2008-12-16 2011-01-27 Millipore Corporation Purification of proteins
SG171446A1 (en) 2008-12-16 2011-07-28 Millipore Corp Stirred tank reactor and method
SG173812A1 (en) 2009-02-27 2011-09-29 Genentech Inc Methods and compositions for protein labelling
US10184937B2 (en) * 2009-03-31 2019-01-22 United Arab Emirates University Minimally invasive assessment of IgE mediated allergy
DE102009030845A1 (de) * 2009-06-26 2010-12-30 Siemens Aktiengesellschaft Verfahren und Kit zur Diagnose oder Prognose einer Kontrastmittelallergie
CN104059955A (zh) 2009-08-11 2014-09-24 弗·哈夫曼-拉罗切有限公司 在无谷氨酰胺的细胞培养基中的蛋白质生产
RU2571929C2 (ru) 2009-09-01 2015-12-27 Дженентек, Инк. Улучшенная очистка белка посредством модифицированного элюирования белка а
KR102218495B1 (ko) 2010-03-22 2021-02-19 제넨테크, 인크. 단백질-함유 제제의 안정화에 유용한 조성물 및 방법
BR112012027828A2 (pt) 2010-05-03 2016-08-09 Genentech Inc composição de matéria, artigo de fabricação e método de redução da viscosidade de uma formulação contendo proteína e de preparação de uma formulação aquosa contendo proteína
SG10201804385YA (en) 2010-05-17 2018-06-28 Emd Millipore Corp Stimulus responsive polymers for the purification of biomolecules
HUE030820T2 (en) 2010-05-28 2017-06-28 Hoffmann La Roche Decreasing Lactate Levels and Enhancing Polypeptide Production by Control of Lactate Dehydrogenase and Pyruvate Dehydrogenase Kinase Expression
WO2011163458A2 (en) 2010-06-24 2011-12-29 Genentech, Inc. Compositions and methods for stabilizing protein-containing formulations
CN103154032A (zh) 2010-08-13 2013-06-12 弗·哈夫曼-拉罗切有限公司 用于疾病治疗的针对IL-1β和IL-18的抗体
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ES2809211T3 (es) 2011-07-08 2021-03-03 Emd Millipore Corp Filtros de profundidad mejorados para procesos biotecnológicos desechables
BR112014015101A8 (pt) 2011-12-22 2021-06-08 Genentech Inc métodos para intensificar eficiência de etapas de cromatografia a jusante para purificação de anticorpos
CN104350156B (zh) 2012-03-27 2019-04-02 弗·哈夫曼-拉罗切有限公司 用于重组蛋白质的改进的收获操作
RU2711089C2 (ru) 2012-05-18 2020-01-15 Дженентек, Инк. Высококонцентрированные составы моноклональных антител
EP2934602B1 (de) 2012-12-19 2019-02-27 Genentech, Inc. Verfahren und zusammensetzungen zur radiohalogen proteinmarkierung
KR102355306B1 (ko) 2014-07-09 2022-01-24 제넨테크, 인크. 세포 은행의 해동 회수를 개선하는 ph 조정
AU2017242031B2 (en) 2016-03-29 2023-07-27 Geltor, Inc. Expression of proteins in gram-negative bacteria wherein the ratio of periplasmic volume to cytoplasmic volume is between 0.5:1 and 10:1
KR102579836B1 (ko) 2016-12-22 2023-09-15 제넨테크, 인크. 동결건조된 폴리펩타이드의 재구성 시간을 감소시키기 위한 방법 및 제제
US11180541B2 (en) 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
EA202092904A1 (ru) 2018-07-03 2021-04-22 Бристол-Маерс Сквибб Компани Способы получения рекомбинантных белков
US20210380923A1 (en) 2018-10-10 2021-12-09 Boehringer Ingelheim International Gmbh Method for membrane gas transfer in high density bioreactor culture
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EP3953380A4 (de) 2019-04-12 2023-01-25 Geltor, Inc. Rekombinantes elastin und herstellung davon
JP2022543781A (ja) 2019-08-01 2022-10-14 ブリストル－マイヤーズ スクイブ カンパニー フェッドバッチ細胞培養におけるタンパク質産生性の改良方法
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Also Published As

Publication number Publication date
WO1995016203A3 (en) 1995-06-29
EP0733207B1 (de) 1997-08-27
CA2176811C (en) 2008-01-29
EP0733207A1 (de) 1996-09-25
JPH09506435A (ja) 1997-06-24
DK0733207T3 (da) 1998-04-20
ES2108566T3 (es) 1997-12-16
JP3507852B2 (ja) 2004-03-15
US5714338A (en) 1998-02-03
CA2176811A1 (en) 1995-06-15
GR3025089T3 (en) 1998-01-30
WO1995016203A2 (en) 1995-06-15
DE69405251T2 (de) 1998-02-05
ATE157455T1 (de) 1997-09-15

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