DK0733207T3 - Fremgangsmåder til diagnose af allergi og screening af anti-allergi-terapeutika - Google Patents
Fremgangsmåder til diagnose af allergi og screening af anti-allergi-terapeutikaInfo
- Publication number
- DK0733207T3 DK0733207T3 DK95905357.0T DK95905357T DK0733207T3 DK 0733207 T3 DK0733207 T3 DK 0733207T3 DK 95905357 T DK95905357 T DK 95905357T DK 0733207 T3 DK0733207 T3 DK 0733207T3
- Authority
- DK
- Denmark
- Prior art keywords
- patient serum
- allergen
- pct
- host cells
- allergy
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16543693A | 1993-12-10 | 1993-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0733207T3 true DK0733207T3 (da) | 1998-04-20 |
Family
ID=22598886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95905357.0T DK0733207T3 (da) | 1993-12-10 | 1994-12-09 | Fremgangsmåder til diagnose af allergi og screening af anti-allergi-terapeutika |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5714338A (de) |
| EP (1) | EP0733207B1 (de) |
| JP (1) | JP3507852B2 (de) |
| AT (1) | ATE157455T1 (de) |
| CA (1) | CA2176811C (de) |
| DE (1) | DE69405251T2 (de) |
| DK (1) | DK0733207T3 (de) |
| ES (1) | ES2108566T3 (de) |
| GR (1) | GR3025089T3 (de) |
| WO (1) | WO1995016203A2 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9526599D0 (en) * | 1995-12-28 | 1996-02-28 | Sandoz Ltd | Elisa test system |
| DE19643427C1 (de) * | 1996-10-22 | 1998-02-12 | Bundesrep Deutschland | Verfahren zur Bestimmung von Allergenen in der Luft |
| US6165799A (en) * | 1996-12-10 | 2000-12-26 | Heska Corporation | Detection of anti-Fc.sub.ε R autoantibodies in asthmatics |
| US7122636B1 (en) * | 1997-02-21 | 2006-10-17 | Genentech, Inc. | Antibody fragment-polymer conjugates and uses of same |
| US6060326A (en) * | 1997-04-07 | 2000-05-09 | Heska Corporation | Method to detect canine IgE and kit therefor |
| FR2765341A1 (fr) * | 1997-06-25 | 1998-12-31 | Alain Funes | Methode pour l'analyse de l'activation des basophiles humains par mesure de l'expression membranaire du marqueur cd63 |
| AU1727500A (en) * | 1998-11-17 | 2000-06-05 | Tanox, Inc. | Bispecific molecules cross-linking itim and itam for therapy |
| AU2001234419A1 (en) * | 2000-01-14 | 2001-07-24 | Tanox, Inc. | Administering ige antagonists during pregnancy to ameliorate allergic diseases in the offspring |
| US6889145B1 (en) | 2000-03-15 | 2005-05-03 | Northwestern University | Three-dimensional model of a Fc region of an IgE antibody and uses thereof |
| EP1195606A1 (de) * | 2000-10-03 | 2002-04-10 | VBC-Genomics Forschungsges.m.b.H. | Allergen-Assay auf Basis von Mikroanordnungen |
| DE10110838C2 (de) * | 2001-03-06 | 2003-04-03 | Mlu Halle Wittenberg | Verfahren zur Diagnostik von Allergien, Pseudoallergien und Intoleranzen |
| FR2831186B1 (fr) * | 2001-10-22 | 2004-06-18 | Aventis Pharma Sa | Production d'heparine a partir de cultures de mastocytes |
| ATE417858T1 (de) | 2002-02-05 | 2009-01-15 | Genentech Inc | Proteinaufreinigung |
| JP4319979B2 (ja) | 2002-04-26 | 2009-08-26 | ジェネンテック・インコーポレーテッド | タンパク質の非アフィニティ精製 |
| WO2005016968A2 (en) | 2003-07-28 | 2005-02-24 | Genentech, Inc. | Reducing protein a leaching during protein a affinity chromatography |
| US7613619B1 (en) * | 2004-03-30 | 2009-11-03 | Harter Michael R | Method for identifying allergens and other influencing agents that may cause a reaction |
| BRPI0515589A (pt) * | 2004-09-02 | 2008-07-29 | Genentech Inc | polipeptìdeos ou anticorpos de ligação de antìgeno isolado, anticorpo isolado, método para regular de forma negativa a atividade de fc(gama)riib, métodos de tratamento, anticorpos biespecìficos isolados, métodos de inibição de uma resposta imune, de supressão na liberação de histamina, de ativação de fc(gama)riib, de inibição da expressão do receptor fc(épsilon)ri, composição e kit |
| US7655229B2 (en) * | 2004-09-02 | 2010-02-02 | Chan Andrew C | Anti-FC-gamma RIIB receptor antibody and uses therefor |
| US7662926B2 (en) * | 2004-09-02 | 2010-02-16 | Genentech, Inc. | Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| ATE505728T1 (de) * | 2005-03-16 | 2011-04-15 | Nutricia Nv | Verfahren zur bestimmung einer allergischen reaktion |
| EP1913393A4 (de) * | 2005-06-16 | 2010-03-03 | Univ California | Paralleler allergietest auf immunbasis im grossmassstab und vorrichtung zur fluoreszenzanregung mit evaneszenzfeld |
| US20080011058A1 (en) * | 2006-03-20 | 2008-01-17 | The Regents Of The University Of California | Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels |
| FR2902799B1 (fr) | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
| AU2007327150B2 (en) * | 2006-12-01 | 2012-07-12 | Statens Serum Institut | Screening method using sample adsorption on filter paper |
| US8569464B2 (en) * | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
| US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
| US8163886B2 (en) * | 2006-12-21 | 2012-04-24 | Emd Millipore Corporation | Purification of proteins |
| AU2008209404B2 (en) | 2007-01-22 | 2012-08-16 | Genentech, Inc. | Polyelectrolyte precipitation and purification of antibodies |
| US8191403B2 (en) * | 2007-03-27 | 2012-06-05 | Richmond Chemical Corporation | Petroleum viscosity measurement and communication system and method |
| AU2008275229B2 (en) | 2007-07-09 | 2014-11-06 | Genentech, Inc. | Prevention of disulfide bond reduction during recombinant production of polypeptides |
| CA2703279C (en) | 2007-10-30 | 2014-04-22 | Genentech, Inc. | Antibody purification by cation exchange chromatography |
| WO2009151514A1 (en) * | 2008-06-11 | 2009-12-17 | Millipore Corporation | Stirred tank bioreactor |
| DK2848625T3 (da) | 2008-08-14 | 2019-10-07 | Genentech Inc | Fremgangsmåder til fjernelse af en kontaminant under anvendelse af ion bytningsmembrankromatografi med forskydning af naturligt forekommende proteiner |
| EP2684570A1 (de) | 2008-09-10 | 2014-01-15 | F. Hoffmann-La Roche AG | Zusammensetzungen und Verfahren zur Prävention des oxidativen Abbaus von Proteinen |
| WO2010074953A1 (en) | 2008-12-16 | 2010-07-01 | Millipore Corporation | Stirred tank reactor and method |
| US20110020327A1 (en) * | 2008-12-16 | 2011-01-27 | Millipore Corporation | Purification of proteins |
| ES2547712T3 (es) | 2009-02-27 | 2015-10-08 | Genentech, Inc. | Métodos y composiciones para el marcado de proteínas |
| US10184937B2 (en) * | 2009-03-31 | 2019-01-22 | United Arab Emirates University | Minimally invasive assessment of IgE mediated allergy |
| DE102009030845A1 (de) * | 2009-06-26 | 2010-12-30 | Siemens Aktiengesellschaft | Verfahren und Kit zur Diagnose oder Prognose einer Kontrastmittelallergie |
| RU2639288C2 (ru) | 2009-08-11 | 2017-12-20 | Дженентек, Инк. | Получение белков в культуральных средах без глутамина |
| EP3736338A1 (de) | 2009-09-01 | 2020-11-11 | F. Hoffmann-La Roche AG | Verbesserte proteinreinigung durch eine modifizierte protein-a-elution |
| KR20180000342A (ko) | 2010-03-22 | 2018-01-02 | 제넨테크, 인크. | 단백질-함유 제제의 안정화에 유용한 조성물 및 방법 |
| BR112012027828A2 (pt) | 2010-05-03 | 2016-08-09 | Genentech Inc | composição de matéria, artigo de fabricação e método de redução da viscosidade de uma formulação contendo proteína e de preparação de uma formulação aquosa contendo proteína |
| US8691918B2 (en) | 2010-05-17 | 2014-04-08 | Emd Millipore Corporation | Stimulus responsive polymers for the purification of biomolecules |
| PL2576580T3 (pl) | 2010-05-28 | 2017-03-31 | F.Hoffmann-La Roche Ag | Zmniejszenie poziomu mleczanu i zwiększenie wytwarzania polipeptydu przez obniżenie poziomu ekspresji dehydrogenazy mleczanowej i kinazy dehydrogenazy pirogronianowej |
| SI3586826T1 (sl) | 2010-06-24 | 2021-09-30 | F. Hoffmann-La Roche Ag | Sestavki in postopki za stabilizacijo formulacij, ki vsebujejo beljakovine |
| CN104474546A (zh) | 2010-08-13 | 2015-04-01 | 弗·哈夫曼-拉罗切有限公司 | 用于疾病治疗的针对IL-1β和IL-18的抗体 |
| WO2012030512A1 (en) | 2010-09-03 | 2012-03-08 | Percivia Llc. | Flow-through protein purification process |
| EP2732021B1 (de) | 2011-07-08 | 2020-05-27 | EMD Millipore Corporation | Verbesserte tiefenfilter für biotechnologische einwegverfahren |
| MY172426A (en) | 2011-12-22 | 2019-11-25 | Genentech Inc | Ion exchange membrane chromatography |
| AU2013240280A1 (en) | 2012-03-27 | 2014-10-16 | Genentech, Inc. | Improved harvest operations for recombinant proteins |
| EP2849723B1 (de) | 2012-05-18 | 2018-05-02 | Genentech, Inc. | Hochkonzentrierte monoklonale antikörperformulierungen |
| EP2934602B1 (de) | 2012-12-19 | 2019-02-27 | Genentech, Inc. | Verfahren und zusammensetzungen zur radiohalogen proteinmarkierung |
| ES2825574T3 (es) | 2014-07-09 | 2021-05-17 | Hoffmann La Roche | Ajuste del pH para mejorar la recuperación por descongelación de bancos de células |
| MX2018011834A (es) | 2016-03-29 | 2019-03-06 | Geltor Inc | Expresión de proteínas en bacterias gram negativas en la que la relación del volumen periplasmático con respecto al volumen citoplasmático está entre 0.5:1 y 10:1. |
| CA3044686A1 (en) | 2016-12-22 | 2018-06-28 | Genentech, Inc. | Methods and formulations for reducing reconstitution time of lyophilized polypeptides |
| US11180541B2 (en) | 2017-09-28 | 2021-11-23 | Geltor, Inc. | Recombinant collagen and elastin molecules and uses thereof |
| AU2019299358A1 (en) | 2018-07-03 | 2021-02-18 | Bristol-Myers Squibb Company | Methods of producing recombinant proteins |
| MA53859A (fr) | 2018-10-10 | 2022-01-19 | Boehringer Ingelheim Int | Procédé de transfert de gaz de membrane dans une culture de bioréacteur à haute densité |
| CN113660953A (zh) | 2019-04-01 | 2021-11-16 | 豪夫迈·罗氏有限公司 | 用于稳定含蛋白质制剂的组合物和方法 |
| SG11202111349QA (en) | 2019-04-12 | 2021-11-29 | Geltor Inc | Recombinant elastin and production thereof |
| KR20220039777A (ko) | 2019-08-01 | 2022-03-29 | 브리스톨-마이어스 스큅 컴퍼니 | 유가식 세포 배양에서 단백질 생산성을 개선시키는 방법 |
| EP4217383A1 (de) | 2020-09-22 | 2023-08-02 | Bristol-Myers Squibb Company | Verfahren zur herstellung therapeutischer proteine |
| CN113495139A (zh) * | 2021-07-07 | 2021-10-12 | 上海清芮科技有限公司 | 一种宠物特应性体质的检测方法 |
| WO2023015234A1 (en) | 2021-08-05 | 2023-02-09 | Bristol-Myers Squibb Company | Cell culture methods for producing therapeutic proteins |
| WO2023049687A1 (en) | 2021-09-21 | 2023-03-30 | Bristol-Myers Squibb Company | Methods of controlling the level of dissolved oxygen (do) in a solution comprising a recombinant protein in a storage container |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4559310A (en) * | 1983-05-20 | 1985-12-17 | Dana Farber Cancer Institute | Assay methods and systems utilizing mast cell clones |
| US4946788A (en) * | 1985-06-11 | 1990-08-07 | Ciba-Geigy Corporation | Purified immunoglobulin-related factor, novel monoclonal antibodies, hybridoma cell lines, processes and applications |
| EP0248211B1 (de) * | 1986-04-30 | 1992-03-11 | Junji Yodoi | Protein und Verfahren zu dessen Herstellung |
| US5180805A (en) * | 1986-07-02 | 1993-01-19 | Research Corporation Limited | Polypeptide competitor for immunoglobulin E |
| GB8727045D0 (en) * | 1987-11-19 | 1987-12-23 | Research Corp Ltd | Immunoglobulin e competitor |
| US4962035A (en) * | 1987-12-01 | 1990-10-09 | President And Fellows Of Harvard College | DNA encoding IgE receptor alpha-subunit or fragment thereof |
| JPH03127997A (ja) * | 1989-10-11 | 1991-05-31 | Kuraray Co Ltd | ヒト１ｇＥ結合因子に特異的なモノクローン抗体、それを産生するハイブリドーマおよびその用途 |
| CA2059842A1 (en) * | 1991-02-11 | 1992-08-12 | Richard A. Chizzonite | Ige-receptor-antibodies |
| WO1993011437A1 (en) * | 1991-12-05 | 1993-06-10 | Board Of Regents Of The University Of Nebraska | Allergen specific immunoglobulin-e producer test for diagnosing allergies |
| GB9224956D0 (en) * | 1992-11-28 | 1993-01-20 | Euro Dpc Ltd | Improvements relating to allergen testing & apparatus |
-
1994
- 1994-12-09 CA CA002176811A patent/CA2176811C/en not_active Expired - Lifetime
- 1994-12-09 AT AT95905357T patent/ATE157455T1/de active
- 1994-12-09 US US08/393,014 patent/US5714338A/en not_active Expired - Lifetime
- 1994-12-09 JP JP51638795A patent/JP3507852B2/ja not_active Expired - Lifetime
- 1994-12-09 DE DE69405251T patent/DE69405251T2/de not_active Expired - Lifetime
- 1994-12-09 ES ES95905357T patent/ES2108566T3/es not_active Expired - Lifetime
- 1994-12-09 EP EP95905357A patent/EP0733207B1/de not_active Expired - Lifetime
- 1994-12-09 DK DK95905357.0T patent/DK0733207T3/da active
- 1994-12-09 WO PCT/US1994/014282 patent/WO1995016203A2/en active IP Right Grant
-
1997
- 1997-10-20 GR GR970402730T patent/GR3025089T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2108566T3 (es) | 1997-12-16 |
| DE69405251D1 (de) | 1997-10-02 |
| JP3507852B2 (ja) | 2004-03-15 |
| GR3025089T3 (en) | 1998-01-30 |
| JPH09506435A (ja) | 1997-06-24 |
| ATE157455T1 (de) | 1997-09-15 |
| WO1995016203A3 (en) | 1995-06-29 |
| EP0733207B1 (de) | 1997-08-27 |
| CA2176811A1 (en) | 1995-06-15 |
| DE69405251T2 (de) | 1998-02-05 |
| US5714338A (en) | 1998-02-03 |
| EP0733207A1 (de) | 1996-09-25 |
| CA2176811C (en) | 2008-01-29 |
| WO1995016203A2 (en) | 1995-06-15 |
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