SE9600683D0 - Azabicyclic esters of carbamic acids useful in therapy - Google Patents
Azabicyclic esters of carbamic acids useful in therapyInfo
- Publication number
- SE9600683D0 SE9600683D0 SE9600683A SE9600683A SE9600683D0 SE 9600683 D0 SE9600683 D0 SE 9600683D0 SE 9600683 A SE9600683 A SE 9600683A SE 9600683 A SE9600683 A SE 9600683A SE 9600683 D0 SE9600683 D0 SE 9600683D0
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- halogen
- hydrogen
- therapy
- och3
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 150000001715 carbamic acids Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 5
- 150000002367 halogens Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- -1 -OR5 Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (29)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9600683A SE9600683D0 (sv) | 1996-02-23 | 1996-02-23 | Azabicyclic esters of carbamic acids useful in therapy |
| ZA9701082A ZA971082B (en) | 1996-02-23 | 1997-02-10 | Azabicyclic esters of carbamic acids useful in therapy. |
| ARP970100618A AR005876A1 (es) | 1996-02-23 | 1997-02-17 | Esteres azabiciclicos de acidos carbamicos utiles en terapia, composicion farmaceutica que incluye a dichos esteres, uso de dichos esteres, metodos parael tratamiento o profilaxis de varios desordenes, enfermedades y adicciones, procedimiento para la preparacion de dichos esteres, intermediarios utilizados |
| IDP970487A ID15969A (id) | 1996-02-23 | 1997-02-20 | Ester azabisiklik asam karbamat yang berguna dalam terapi. |
| EE9800250A EE9800250A (et) | 1996-02-23 | 1997-02-21 | Teraapias kasutatavad karbaamhapete asabitsüklilised estrid |
| PCT/SE1997/000294 WO1997030998A1 (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| CZ19982659A CZ289110B6 (cs) | 1996-02-23 | 1997-02-21 | Azabicyklické estery pro léčení poruch psychotických nebo naruąení intelektu |
| HK99102514.5A HK1017357B (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| SK1027-98A SK102798A3 (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| DE69713295T DE69713295T2 (de) | 1996-02-23 | 1997-02-21 | Azabicyclishe carbaniumsaureester zur therapeutsichen verwendung |
| TR1998/01642T TR199801642T2 (xx) | 1996-02-23 | 1997-02-21 | Tedavide faydal� olan karbamik asitlerin azabisiklik esterleri. |
| RU98117804A RU2172739C2 (ru) | 1996-02-23 | 1997-02-21 | Азабициклические сложные эфиры карбаминовых кислот, способы их получения, фармацевтическая композиция и промежуточные соединения |
| NZ331145A NZ331145A (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in treating disorders involving reduced cholinergic function |
| PL97328614A PL328614A1 (en) | 1996-02-23 | 1997-02-21 | Azabicyclic carbaminic esters useful in therapy |
| BR9707616A BR9707616A (pt) | 1996-02-23 | 1997-02-21 | Composto composiç o farmacéutica utilização de um composto e processo para a preparação de um composto para o tratamento ou profilaxia de distúrbios de deficiéncia intelectual ou profilaxia da doença de parkinson doença de huntington síndrome de tourette esclerose amiotrófica lateral ou distúrbios neurodegenerativos |
| EP97905544A EP0885221B1 (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| HU9901273A HUP9901273A3 (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| US08/836,143 US5998429A (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| AU22387/97A AU706944B2 (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| IL12562097A IL125620A (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of cereal phenylic and pyridylic acids, their preparations and medicinal preparations containing them |
| CN97192461A CN1063749C (zh) | 1996-02-23 | 1997-02-21 | 用于治疗的氨基甲酸的氮杂双环酯 |
| CA002246051A CA2246051A1 (en) | 1996-02-23 | 1997-02-21 | Azabicyclic esters of carbamic acids useful in therapy |
| AT97905544T ATE219081T1 (de) | 1996-02-23 | 1997-02-21 | Azabicyclishe carbaniumsaureester zur therapeutsichen verwendung |
| KR1019980706579A KR19990087184A (ko) | 1996-02-23 | 1997-02-21 | 치료에 유용한 카르밤산의 아자비시클릭 에스테르 |
| JP9530075A JP2000505452A (ja) | 1996-02-23 | 1997-02-21 | 治療に有用なカルバミン酸のアザビシクロエステル |
| NO983711A NO983711L (no) | 1996-02-23 | 1998-08-13 | Azabicykliske estere av karbaminsyrer som er nyttige i terapi |
| IS4830A IS4830A (is) | 1996-02-23 | 1998-08-20 | Asabísýklískir esterar af karbamiksýrum sem eru gagnlegir við læknismeðferð |
| US09/276,689 US6054464A (en) | 1996-02-23 | 1999-03-26 | Azabicyclic esters of carbamic acids useful in therapy |
| IL13758500A IL137585A0 (en) | 1996-02-23 | 2000-07-30 | Azabicyclic esters of phenyl and pyridyl carbamic adics, their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9600683A SE9600683D0 (sv) | 1996-02-23 | 1996-02-23 | Azabicyclic esters of carbamic acids useful in therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9600683D0 true SE9600683D0 (sv) | 1996-02-23 |
Family
ID=20401517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9600683A SE9600683D0 (sv) | 1996-02-23 | 1996-02-23 | Azabicyclic esters of carbamic acids useful in therapy |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US5998429A (cs) |
| EP (1) | EP0885221B1 (cs) |
| JP (1) | JP2000505452A (cs) |
| KR (1) | KR19990087184A (cs) |
| CN (1) | CN1063749C (cs) |
| AR (1) | AR005876A1 (cs) |
| AT (1) | ATE219081T1 (cs) |
| AU (1) | AU706944B2 (cs) |
| BR (1) | BR9707616A (cs) |
| CA (1) | CA2246051A1 (cs) |
| CZ (1) | CZ289110B6 (cs) |
| DE (1) | DE69713295T2 (cs) |
| EE (1) | EE9800250A (cs) |
| HU (1) | HUP9901273A3 (cs) |
| ID (1) | ID15969A (cs) |
| IL (2) | IL125620A (cs) |
| IS (1) | IS4830A (cs) |
| NO (1) | NO983711L (cs) |
| NZ (1) | NZ331145A (cs) |
| PL (1) | PL328614A1 (cs) |
| RU (1) | RU2172739C2 (cs) |
| SE (1) | SE9600683D0 (cs) |
| SK (1) | SK102798A3 (cs) |
| TR (1) | TR199801642T2 (cs) |
| WO (1) | WO1997030998A1 (cs) |
| ZA (1) | ZA971082B (cs) |
Families Citing this family (129)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5977144A (en) * | 1992-08-31 | 1999-11-02 | University Of Florida | Methods of use and compositions for benzylidene- and cinnamylidene-anabaseines |
| US7214686B2 (en) | 1997-06-30 | 2007-05-08 | Targacept, Inc. | Pharmaceutical compositions and methods for effecting dopamine release |
| US6632823B1 (en) * | 1997-12-22 | 2003-10-14 | Merck & Co., Inc. | Substituted pyridine compounds useful as modulators of acetylcholine receptors |
| US6277870B1 (en) * | 1998-05-04 | 2001-08-21 | Astra Ab | Use |
| FR2804430B1 (fr) * | 2000-01-28 | 2002-03-22 | Sanofi Synthelabo | Derives de 4-heteroaryl-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique |
| GB0010955D0 (en) | 2000-05-05 | 2000-06-28 | Novartis Ag | Organic compounds |
| US8914114B2 (en) | 2000-05-23 | 2014-12-16 | The Feinstein Institute For Medical Research | Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation |
| US6492385B2 (en) | 2000-08-18 | 2002-12-10 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
| US6492386B2 (en) * | 2000-08-18 | 2002-12-10 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
| JP2004506735A (ja) | 2000-08-18 | 2004-03-04 | ファルマシア・アンド・アップジョン・カンパニー | 疾患治療用キヌクリジン置換アリール化合物 |
| WO2002016357A2 (en) * | 2000-08-18 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
| AU2001282875A1 (en) | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
| AU2001284646A1 (en) | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
| AU2001282910A1 (en) * | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic) acetylcholine receptor ligands |
| PE20021019A1 (es) | 2001-04-19 | 2002-11-13 | Upjohn Co | Grupos azabiciclicos sustituidos |
| AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
| AR036041A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen |
| BR0212101A (pt) | 2001-08-24 | 2004-08-24 | Pharmacia & Up John Company | 7-aza [2.2.1] biciclo-heptanos substituìdos com heteroarila para o tratamento de doenças |
| MXPA04000779A (es) * | 2001-08-24 | 2004-04-20 | Pharmacia & Up John Company | 7-aza[2.2.1]bicicloheptanos sustituidos con arilo para el tratamiento de enfermedades. |
| EP1425286B1 (en) * | 2001-09-12 | 2007-02-28 | Pharmacia & Upjohn Company LLC | Substituted 7-aza-[2.2.1]bicycloheptanes for the treatment of diseases |
| ATE551340T1 (de) * | 2001-10-02 | 2012-04-15 | Pharmacia & Upjohn Co Llc | Azabicyclisch- substituierte annelierte heteroaryl-verbinungen für die behandlung von krankheiten |
| US6849620B2 (en) | 2001-10-26 | 2005-02-01 | Pfizer Inc | N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease |
| EP1442041A1 (en) | 2001-11-08 | 2004-08-04 | PHARMACIA & UPJOHN COMPANY | Azabicyclic-substituted-heteroaryl compounds for the treatment of disease |
| MXPA04004373A (es) * | 2001-11-09 | 2004-08-11 | Upjohn Co | Compuestos heterociclicos condensados con fenilo azabiciclo para el tratamiento de enfermedades. |
| WO2003051302A2 (en) | 2001-12-14 | 2003-06-26 | Targacept, Inc. | Methods and compositions for treatment of central nervous system disorders |
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| BR0307714A (pt) | 2002-02-15 | 2005-02-09 | Upjohn Co | Benzoilamidas substituìdas com azabiciclo e tioamidas para tratamento de distúrbios relacionados ao cns |
| BR0307782A (pt) * | 2002-02-19 | 2005-01-04 | Upjohn Co | Compostos azabiciclo para o tratamento de doença |
| MXPA04008038A (es) * | 2002-02-19 | 2004-11-26 | Upjohn Co | Carboxamidas heteroaromaticas biciclicas condensadas con puente de n para el tratamiento de enfermedades. |
| US7001900B2 (en) * | 2002-02-20 | 2006-02-21 | Pfizer Inc. | Azabicyclic compounds for the treatment of disease |
| DE10211415A1 (de) * | 2002-03-15 | 2003-09-25 | Bayer Ag | Bicyclische N-Biarylamide |
| DE10211416A1 (de) * | 2002-03-15 | 2003-09-25 | Bayer Ag | Essig- und Propionsäureamide |
| AU2003253686A1 (en) | 2002-08-01 | 2004-02-23 | Pharmacia & Upjohn Company Llc | 1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity |
| WO2004019943A1 (en) | 2002-08-30 | 2004-03-11 | Memory Pharmaceuticals Corporation | Anabaseine derivatives useful in the treatment of neurodegenerative diseases |
| GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
| HRP20050266A2 (en) | 2002-09-25 | 2005-10-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, and benzoisothiazoles, and uses thereof |
| AU2003269401A1 (en) * | 2002-11-01 | 2004-05-25 | Pharmacia & Upjohn Company Llc | Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases |
| US7238715B2 (en) * | 2002-12-06 | 2007-07-03 | The Feinstein Institute For Medical Research | Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists |
| WO2004052365A2 (en) | 2002-12-06 | 2004-06-24 | North Shore-Long Island Jewish Research Institute | Inhibition of inflamation using alpha 7 receptor-binding cholinergic agonists |
| CA2519265A1 (en) * | 2003-03-28 | 2004-10-07 | Pharmacia & Upjohn Company Llc | Positive allosteric modulators of the nicotinic acetylcholine receptor |
| GB0310867D0 (en) | 2003-05-12 | 2003-06-18 | Novartis Ag | Organic compounds |
| DE10334724A1 (de) * | 2003-07-30 | 2005-02-24 | Bayer Healthcare Ag | N-Biarylamide |
| ATE451368T1 (de) | 2003-10-15 | 2009-12-15 | Targacept Inc | Azabicyclische verbindungen zur linderung von schmerzen und zur behandlung von erkrankungen des zentralen nervensystems |
| FR2861076B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
| AU2004309367B2 (en) | 2003-12-22 | 2010-04-01 | Memory Pharmaceuticals Corporation | Indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof |
| US20050137217A1 (en) * | 2003-12-22 | 2005-06-23 | Jianguo Ji | Spirocyclic quinuclidinic ether derivatives |
| FR2865208B1 (fr) * | 2004-01-16 | 2009-01-16 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo[3.2.1]octanecarboxmique, leur preparation et leur application en therapeutique |
| EP2336128A1 (en) | 2004-03-25 | 2011-06-22 | Memory Pharmaceuticals Corporation | Benzoisothiazoles and preparation and uses thereof |
| US10912712B2 (en) | 2004-03-25 | 2021-02-09 | The Feinstein Institutes For Medical Research | Treatment of bleeding by non-invasive stimulation |
| ATE487716T1 (de) | 2004-04-22 | 2010-11-15 | Memory Pharm Corp | Indole, 1h-indazole, 1,2-benzisoxazole, 1,2- benzoisothiazole, deren herstellung und verwendungen |
| JP2007538011A (ja) | 2004-05-07 | 2007-12-27 | メモリー・ファーマシューティカルズ・コーポレイション | 1h−インダゾール、ベンゾチアゾール、1,2−ベンゾイソキサゾール、1,2−ベンゾイソチアゾール、およびクロモン、ならびにそれらの調製および使用 |
| PE20060437A1 (es) | 2004-06-18 | 2006-06-08 | Novartis Ag | COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR |
| GB0415746D0 (en) | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
| GB0424564D0 (en) * | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
| ES2342675T3 (es) | 2004-12-22 | 2010-07-12 | Memory Pharmaceuticals Corporation | Ligandos del receptor alfa-7 nicotinico contra enfermedades relacionadas con el snc. |
| US11207518B2 (en) | 2004-12-27 | 2021-12-28 | The Feinstein Institutes For Medical Research | Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU482990A1 (ru) * | 1973-09-03 | 1978-04-15 | Предприятие П/Я Г-4059 | Способ получени 1,4-диазабицикло(2,2,2)-октана |
| DE8817121U1 (de) * | 1988-11-22 | 1993-02-04 | Boehringer Ingelheim Kg, 55218 Ingelheim | Neue Quinuclidine |
| JP3169188B2 (ja) * | 1991-01-31 | 2001-05-21 | 杏林製薬株式会社 | カルバミン酸誘導体及びその製造方法 |
| US5530018A (en) * | 1994-02-04 | 1996-06-25 | G. D. Searle & Co. | Meso-azanoradamantanes |
| US5468875A (en) * | 1994-12-22 | 1995-11-21 | American Home Products Corporation | 1-azabicycloheptane derivatives |
-
1996
- 1996-02-23 SE SE9600683A patent/SE9600683D0/xx unknown
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1997
- 1997-02-10 ZA ZA9701082A patent/ZA971082B/xx unknown
- 1997-02-17 AR ARP970100618A patent/AR005876A1/es not_active Application Discontinuation
- 1997-02-20 ID IDP970487A patent/ID15969A/id unknown
- 1997-02-21 NZ NZ331145A patent/NZ331145A/en unknown
- 1997-02-21 TR TR1998/01642T patent/TR199801642T2/xx unknown
- 1997-02-21 KR KR1019980706579A patent/KR19990087184A/ko not_active Withdrawn
- 1997-02-21 IL IL12562097A patent/IL125620A/en not_active IP Right Cessation
- 1997-02-21 SK SK1027-98A patent/SK102798A3/sk unknown
- 1997-02-21 PL PL97328614A patent/PL328614A1/xx unknown
- 1997-02-21 EP EP97905544A patent/EP0885221B1/en not_active Expired - Lifetime
- 1997-02-21 WO PCT/SE1997/000294 patent/WO1997030998A1/en not_active Ceased
- 1997-02-21 EE EE9800250A patent/EE9800250A/xx unknown
- 1997-02-21 CZ CZ19982659A patent/CZ289110B6/cs not_active IP Right Cessation
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- 1997-02-21 RU RU98117804A patent/RU2172739C2/ru active
- 1997-02-21 AT AT97905544T patent/ATE219081T1/de active
- 1997-02-21 DE DE69713295T patent/DE69713295T2/de not_active Expired - Fee Related
- 1997-02-21 CA CA002246051A patent/CA2246051A1/en not_active Abandoned
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