BR0212101A - 7-aza [2.2.1] biciclo-heptanos substituìdos com heteroarila para o tratamento de doenças - Google Patents

7-aza [2.2.1] biciclo-heptanos substituìdos com heteroarila para o tratamento de doenças

Info

Publication number
BR0212101A
BR0212101A BR0212101-8A BR0212101A BR0212101A BR 0212101 A BR0212101 A BR 0212101A BR 0212101 A BR0212101 A BR 0212101A BR 0212101 A BR0212101 A BR 0212101A
Authority
BR
Brazil
Prior art keywords
aza
disease
treatment
bicycloheptanes
heteroaryl substituted
Prior art date
Application number
BR0212101-8A
Other languages
English (en)
Inventor
Donn G Wishka
Jason K Myers
Bruce N Rogers
Eric Jon Jacobsen
David W Piotrowski
Jeffrey W Corbett
Alice L Bodnar
Vincent E Groppi Jr
Original Assignee
Pharmacia & Up John Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Up John Company filed Critical Pharmacia & Up John Company
Publication of BR0212101A publication Critical patent/BR0212101A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

"7-AZA [2.2.1] BICICLO-HEPTANOS SUBSTITUìDOS COM HETEROARILA PARA O TRATAMENTO DE DOENçAS". A invenção proporciona compostos da Fórmula I: Fórmula I em que R~ 1~, R~ 2~, R~ 4~, R~ 6~, X, e W são aqui definidos. Estes compostos podem estar na forma de sais ou composições, podem estar em forma enanciomérica pura ou misturas racêmicas, e são úteis em produtos farmacêuticos utilizados para tratar doenças nas quais se sabe que <244>7 está envolvido.
BR0212101-8A 2001-08-24 2002-08-14 7-aza [2.2.1] biciclo-heptanos substituìdos com heteroarila para o tratamento de doenças BR0212101A (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US31485101P 2001-08-24 2001-08-24
US31477301P 2001-08-24 2001-08-24
US31477201P 2001-08-24 2001-08-24
US31476801P 2001-08-24 2001-08-24
US38871202P 2002-06-14 2002-06-14
PCT/US2002/021326 WO2003018585A1 (en) 2001-08-24 2002-08-14 Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease

Publications (1)

Publication Number Publication Date
BR0212101A true BR0212101A (pt) 2004-08-24

Family

ID=27540993

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212101-8A BR0212101A (pt) 2001-08-24 2002-08-14 7-aza [2.2.1] biciclo-heptanos substituìdos com heteroarila para o tratamento de doenças

Country Status (6)

Country Link
US (1) US6562816B2 (pt)
EP (1) EP1419161A1 (pt)
JP (1) JP2005504058A (pt)
BR (1) BR0212101A (pt)
CA (1) CA2458375A1 (pt)
WO (1) WO2003018585A1 (pt)

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KR101928505B1 (ko) * 2011-01-28 2018-12-12 에스케이바이오팜 주식회사 피리돈 유도체 및 이를 포함하는 약학적 조성물
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Also Published As

Publication number Publication date
JP2005504058A (ja) 2005-02-10
CA2458375A1 (en) 2003-03-06
EP1419161A1 (en) 2004-05-19
US6562816B2 (en) 2003-05-13
WO2003018585A1 (en) 2003-03-06
US20030069290A1 (en) 2003-04-10

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.