SE9101957D0 - Blandningar av polysackarider med laag molekylvikt samt framstaellning och anvaendning av desamma - Google Patents

Blandningar av polysackarider med laag molekylvikt samt framstaellning och anvaendning av desamma

Info

Publication number
SE9101957D0
SE9101957D0 SE9101957A SE9101957A SE9101957D0 SE 9101957 D0 SE9101957 D0 SE 9101957D0 SE 9101957 A SE9101957 A SE 9101957A SE 9101957 A SE9101957 A SE 9101957A SE 9101957 D0 SE9101957 D0 SE 9101957D0
Authority
SE
Sweden
Prior art keywords
molecular weight
mixtures
preparation
application
low molecular
Prior art date
Application number
SE9101957A
Other languages
English (en)
Other versions
SE506267C2 (sv
SE9101957L (sv
Inventor
R Debrie
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9398013&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE9101957(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of SE9101957D0 publication Critical patent/SE9101957D0/sv
Publication of SE9101957L publication Critical patent/SE9101957L/sv
Publication of SE506267C2 publication Critical patent/SE506267C2/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE9101957A 1990-06-26 1991-06-25 Blandningar av polysackarider med låg molekylvikt samt framställning och användning av desamma SE506267C2 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9008013A FR2663639B1 (fr) 1990-06-26 1990-06-26 Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.

Publications (3)

Publication Number Publication Date
SE9101957D0 true SE9101957D0 (sv) 1991-06-25
SE9101957L SE9101957L (sv) 1991-12-27
SE506267C2 SE506267C2 (sv) 1997-11-24

Family

ID=9398013

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9101957A SE506267C2 (sv) 1990-06-26 1991-06-25 Blandningar av polysackarider med låg molekylvikt samt framställning och användning av desamma

Country Status (26)

Country Link
US (1) US5389618A (sv)
JP (1) JP3287363B2 (sv)
KR (1) KR0185586B1 (sv)
AT (1) AT398976B (sv)
AU (1) AU643531B2 (sv)
BE (1) BE1006827A3 (sv)
CA (1) CA2045433C (sv)
CH (1) CH682236A5 (sv)
DK (1) DK176524B1 (sv)
ES (1) ES2036922B9 (sv)
FI (1) FI104490B (sv)
FR (1) FR2663639B1 (sv)
GB (1) GB2245898B (sv)
GR (1) GR1000763B (sv)
HU (1) HU210925B (sv)
IE (1) IE66341B1 (sv)
IL (1) IL98604A (sv)
IT (1) IT1248557B (sv)
LU (1) LU87957A1 (sv)
MX (1) MX25829A (sv)
NL (1) NL194947C (sv)
NO (1) NO304991B1 (sv)
NZ (1) NZ238691A (sv)
PT (1) PT98102B (sv)
SE (1) SE506267C2 (sv)
ZA (1) ZA914869B (sv)

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US5849721A (en) * 1992-02-07 1998-12-15 Rhone-Poulenc Rorer S.A. Sulfated polysaccharides obtained from heparin, preparation process, pharmaceutical composition and use thereof
FR2687158B1 (fr) * 1992-02-07 1995-06-30 Rhone Poulenc Rorer Sa Polysaccharides sulfates, procede de preparation, composition pharmaceutique et utilisation.
CN1115182A (zh) * 1993-09-30 1996-01-17 生化学工业株式会社 抗血栓剂
US6597996B1 (en) 1999-04-23 2003-07-22 Massachusetts Institute Of Technology Method for indentifying or characterizing properties of polymeric units
CN1371391A (zh) * 1999-06-30 2002-09-25 汉密尔顿市医院研究发展有限公司 抑制凝血相关凝血因子的肝素成分
JP4897991B2 (ja) * 1999-07-23 2012-03-14 ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ 超低分子量ヘパリン組成物
AU1594801A (en) * 1999-11-12 2001-06-06 Emisphere Technologies, Inc. Liquid heparin formulation
US6608042B2 (en) 2000-03-28 2003-08-19 Aventis Pharma, S.A. Pharmaceutical compositions containing oligosaccharides, the novel oligosaccharides and preparation thereof
US6969705B2 (en) * 2000-07-21 2005-11-29 Aventis Pharma S.A. Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
AU2001291549A1 (en) * 2000-09-08 2002-03-22 Hamilton Civic Hospitals Research Development Inc. Antithrombotic compositions
WO2002047696A1 (de) 2000-12-16 2002-06-20 Aventis Pharma Deutschland Gmbh Verwendung von niedermolekularen heparin zur behandlung von osteoarthrose
DE10141106A1 (de) * 2001-08-22 2003-03-13 Aventis Pharma Gmbh Verwendung von Heparinoid-Derivaten zur Behandlung und Diagnose von mit Heparinoiden behandelbaren Erkrankungen
JP2005505537A (ja) * 2001-08-28 2005-02-24 レオ・ファーマ・アクティーゼルスカブ 低分子量ヘパリンと低分子量デルマタン硫酸とを含む抗血栓組成物
US7084118B2 (en) 2002-02-22 2006-08-01 Genentech, Inc. Combination treatment with t-PA variant and low molecular weight heparin
EP1518120A4 (en) 2002-03-11 2008-08-13 Momenta Pharmaceuticals Inc ANALYSIS OF SULFATE POLYSACCHARIDES
US20030236221A1 (en) * 2002-06-20 2003-12-25 Chemi Spa Process for the preparation of esters of heparin
ES2282368T3 (es) * 2002-06-20 2007-10-16 Chemi S.P.A. Procedimiento para la preparacion de esteres de heparina.
US20040265943A1 (en) * 2002-09-23 2004-12-30 Aventis Pharma S.A. Method for quantitatively determining specific groups constituting heparins or low molecular weight heparins
FR2844808B1 (fr) * 2002-09-23 2005-02-25 Aventis Pharma Sa Methode de determination de groupements specifiques constituant les heparines ou les heparines de bas poids moleculaire
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
EP1587408A4 (en) * 2002-12-20 2007-09-05 Momenta Pharmaceuticals Inc GLYCAN MARKER FOR DIAGNOSIS AND MONITORING OF DISEASES
JP2006526592A (ja) * 2003-06-05 2006-11-24 センテリオン 血管由来の欠損に関連する高コレステロール血症または糖尿病の治療のための、線維芽細胞成長因子をコードするプラスミド
US7956046B2 (en) 2003-07-24 2011-06-07 Aventis Pharma S.A. Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
ITMI20031679A1 (it) * 2003-08-29 2005-02-28 Opocrin Spa Processo per la produzione di eparine a basso peso
US20050186679A1 (en) * 2004-02-24 2005-08-25 Christian Viskov Method for determining specific groups constituting heparins or low molecular weight heparins
EP1582531A1 (en) 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
US20050261241A1 (en) * 2004-05-19 2005-11-24 Celsus Biopharmaceuticals, Inc. Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
GB0509433D0 (en) * 2005-05-09 2005-06-15 Uni For Milj Og Biovitenskap Method
ATE552004T1 (de) 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
US20070154546A1 (en) * 2005-12-30 2007-07-05 Zhang Jack Y Sustained release pharmaceutical compositions
CN100436483C (zh) * 2006-05-24 2008-11-26 杭州九源基因工程有限公司 一种依诺肝素钠的纯化生产方法
JP2009538386A (ja) 2006-05-25 2009-11-05 モメンタ ファーマシューティカルズ インコーポレイテッド 低分子量ヘパリン組成物およびその使用
US8101733B1 (en) 2006-06-27 2012-01-24 Momenta Pharmaceuticals, Inc. Methods of evaluating mixtures of polysaccharides
US7968082B1 (en) 2007-01-26 2011-06-28 Momenta Pharmaceuticals, Inc. Evaluating mixtures of low molecular weight heparins by NMR
US7790466B1 (en) 2007-01-26 2010-09-07 Momenta Pharmaceuticals, Inc. Evaluating mixtures of low molecular weight heparins by chain profiles or chain mapping
FR2912409B1 (fr) * 2007-02-14 2012-08-24 Sanofi Aventis Heparines de bas poids moleculaire comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine leur procede de preparation,leur utilisation
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
WO2009141821A1 (en) * 2008-05-20 2009-11-26 Crystal Clear Partnership Separation of polysaccharides by charge density gradient
EP2233145A1 (en) 2009-03-19 2010-09-29 Sanofi-Aventis A dose of AVE5026 for the treatment of venous thromboembolism in patients with severe renal impairment
ES2817779T3 (es) * 2010-01-19 2021-04-08 Momenta Pharmaceuticals Inc Evaluación de preparaciones de heparina
US9012229B2 (en) 2011-01-28 2015-04-21 Hangzhou Jiuyuan Gene Engineering Co., Ltd. Capillary electrophoresis method for fine structural analysis of enoxaparin sodium
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
AR085961A1 (es) 2011-04-11 2013-11-06 Sanofi Sa Polisacaridos que poseen dos sitios de union a la antitrombina iii, metodo para prepararlos y composiciones farmaceuticas que los contienen
CN102603925B (zh) * 2012-03-21 2013-12-11 东营天东制药有限公司 一种由粗品肝素钠直接生产依诺肝素钠的方法
CN102603926B (zh) * 2012-03-27 2014-04-30 烟台东诚生化股份有限公司 一种高效价肝素钠制备新工艺
CN102633908A (zh) * 2012-05-02 2012-08-15 雷晓刚 一种高品质超低分子量肝素的制备方法
RU2512768C1 (ru) * 2012-12-18 2014-04-10 Федеральное бюджетное учреждение "Государственный институт кровезаменителей и медицинских препаратов (ФБУ "ГИКиМП") Способ получения низкомолекулярного гепарина
CN103145868B (zh) * 2013-01-07 2015-09-16 中国科学院昆明植物研究所 一种低分子量糖胺聚糖衍生物及其药物组合物和其制备方法与应用
CN103175925B (zh) * 2013-03-20 2014-12-03 山东辰中生物制药有限公司 依诺肝素钠生产过程中肝素苄基酯的酯化率的检测方法
CN103214591B (zh) * 2013-04-12 2015-11-04 中国科学院昆明植物研究所 一种含末端2,5-脱水塔罗糖或其衍生物的低分子量糖胺聚糖衍生物
GB2515315A (en) * 2013-06-19 2014-12-24 Dilafor Ab New Processes
GB2542064B (en) * 2015-01-20 2020-11-18 Univ California Unit aerosol doses for anticoagulation
CN109666086B (zh) * 2018-11-05 2020-12-22 上海宝维医药技术有限公司 一种高纯度肝素季铵盐的制备方法及其应用
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
CN114616340A (zh) 2019-07-09 2022-06-10 奥普蒂姆维亚有限公司 合成抗凝血多糖的方法

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Also Published As

Publication number Publication date
NZ238691A (en) 1992-07-28
GR910100270A (en) 1992-08-25
ES2036922B1 (es) 1994-03-01
HU210925B (en) 1995-09-28
FI104490B (sv) 2000-02-15
KR920000792A (ko) 1992-01-29
AT398976B (de) 1995-02-27
NO912485L (no) 1991-12-27
IE912216A1 (en) 1992-01-01
GR1000763B (el) 1992-12-30
CA2045433C (fr) 2002-07-30
ITMI911757A0 (it) 1991-06-26
GB2245898A (en) 1992-01-15
GB9113589D0 (en) 1991-08-14
HUT57796A (en) 1991-12-30
SE506267C2 (sv) 1997-11-24
FI913101A0 (fi) 1991-06-25
NL9101049A (nl) 1992-01-16
AU643531B2 (en) 1993-11-18
JPH04226101A (ja) 1992-08-14
ZA914869B (en) 1992-04-29
AU7928891A (en) 1992-01-02
DK124391D0 (da) 1991-06-25
CH682236A5 (sv) 1993-08-13
PT98102A (pt) 1992-03-31
NO912485D0 (no) 1991-06-25
DK176524B1 (da) 2008-07-14
IL98604A0 (en) 1992-07-15
GB2245898B (en) 1993-10-06
MX25829A (es) 1993-10-01
US5389618A (en) 1995-02-14
PT98102B (pt) 1998-11-30
FR2663639B1 (fr) 1994-03-18
KR0185586B1 (ko) 1999-04-01
DK124391A (da) 1991-12-27
ITMI911757A1 (it) 1992-12-26
ES2036922B9 (es) 2012-07-30
LU87957A1 (fr) 1993-01-15
NL194947B (nl) 2003-04-01
NL194947C (nl) 2003-08-04
ATA128191A (de) 1994-07-15
IE66341B1 (en) 1995-12-27
SE9101957L (sv) 1991-12-27
FR2663639A1 (fr) 1991-12-27
JP3287363B2 (ja) 2002-06-04
IL98604A (en) 1998-08-15
BE1006827A3 (fr) 1995-01-03
ES2036922A1 (es) 1993-06-01
IT1248557B (it) 1995-01-19
CA2045433A1 (fr) 1991-12-27
NO304991B1 (no) 1999-03-15
FI913101A (fi) 1991-12-27

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