DK196886D0 - Fremstilling af polysaccharider - Google Patents

Fremstilling af polysaccharider

Info

Publication number
DK196886D0
DK196886D0 DK196886A DK196886A DK196886D0 DK 196886 D0 DK196886 D0 DK 196886D0 DK 196886 A DK196886 A DK 196886A DK 196886 A DK196886 A DK 196886A DK 196886 D0 DK196886 D0 DK 196886D0
Authority
DK
Denmark
Prior art keywords
heparin
lmw
molecular weight
depolymerization
polydispersity
Prior art date
Application number
DK196886A
Other languages
English (en)
Inventor
Joergen Ilum Nielsen
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK196886A priority Critical patent/DK196886D0/da
Publication of DK196886D0 publication Critical patent/DK196886D0/da
Priority to ES87303835T priority patent/ES2052559T3/es
Priority to AT87303835T priority patent/ATE84801T1/de
Priority to US07/043,960 priority patent/US5106734A/en
Priority to NO871784A priority patent/NO167577C/no
Priority to EP87303835A priority patent/EP0244235B1/en
Priority to FI871909A priority patent/FI89943C/fi
Priority to DE8787303835T priority patent/DE3783644T2/de
Priority to DK217087A priority patent/DK162108C/da
Priority to JP62104845A priority patent/JPS62283102A/ja
Priority to AU72253/87A priority patent/AU585709B2/en
Priority to CA000536095A priority patent/CA1334080C/en
Priority to IE115287A priority patent/IE60409B1/en
Priority to GR930400176T priority patent/GR3006929T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK196886A 1986-04-30 1986-04-30 Fremstilling af polysaccharider DK196886D0 (da)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DK196886A DK196886D0 (da) 1986-04-30 1986-04-30 Fremstilling af polysaccharider
DK217087A DK162108C (da) 1986-04-30 1987-04-29 Fremgangsmaade til fremstilling af lmw-heparin
FI871909A FI89943C (fi) 1986-04-30 1987-04-29 Foerfarande foer framstaellning av heparin med laog molekylvikt
AT87303835T ATE84801T1 (de) 1986-04-30 1987-04-29 Verfahren zur herstellung von heparin mit niedrigem molekulargewicht.
US07/043,960 US5106734A (en) 1986-04-30 1987-04-29 Process of using light absorption to control enzymatic depolymerization of heparin to produce low molecular weight heparin
NO871784A NO167577C (no) 1986-04-30 1987-04-29 Fremgangsmaate for fremstilling av lmv-heparin ved enzymatisk depolymerisering.
EP87303835A EP0244235B1 (en) 1986-04-30 1987-04-29 Process for the preparation of lmw-heparin
ES87303835T ES2052559T3 (es) 1986-04-30 1987-04-29 Procedimiento para preparar heparina de bajo peso molecular.
DE8787303835T DE3783644T2 (de) 1986-04-30 1987-04-29 Verfahren zur herstellung von heparin mit niedrigem molekulargewicht.
JP62104845A JPS62283102A (ja) 1986-04-30 1987-04-30 Ｌｍｗ−ヘパリンの調製方法
AU72253/87A AU585709B2 (en) 1986-04-30 1987-04-30 Process for the preparation of LMW-heparin
CA000536095A CA1334080C (en) 1986-04-30 1987-04-30 Process for the preparation of lmw-heparin
IE115287A IE60409B1 (en) 1986-04-30 1987-05-11 Process for the preparation of lmw-heparin
GR930400176T GR3006929T3 (da) 1986-04-30 1993-01-28

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK196886A DK196886D0 (da) 1986-04-30 1986-04-30 Fremstilling af polysaccharider

Publications (1)

Publication Number Publication Date
DK196886D0 true DK196886D0 (da) 1986-04-30

Family

ID=8109192

Family Applications (1)

Application Number Title Priority Date Filing Date
DK196886A DK196886D0 (da) 1986-04-30 1986-04-30 Fremstilling af polysaccharider

Country Status (12)

Country Link
EP (1) EP0244235B1 (da)
JP (1) JPS62283102A (da)
AT (1) ATE84801T1 (da)
AU (1) AU585709B2 (da)
CA (1) CA1334080C (da)
DE (1) DE3783644T2 (da)
DK (1) DK196886D0 (da)
ES (1) ES2052559T3 (da)
FI (1) FI89943C (da)
GR (1) GR3006929T3 (da)
IE (1) IE60409B1 (da)
NO (1) NO167577C (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK196986D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider
FR2663639B1 (fr) * 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
USRE38743E1 (en) 1990-06-26 2005-06-14 Aventis Pharma S.A. Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
FR2675806B1 (fr) * 1991-04-23 1994-06-10 Rhone Poulenc Rorer Sa Polysaccharides sulfates, procede de preparation, composition pharmaceutique et utilisation.
US5707973A (en) * 1991-04-23 1998-01-13 Rhone-Poulenc Rorer S.A. Sulfated polysaccharids for treatment or prevention of thromboses
US5744457A (en) * 1995-03-31 1998-04-28 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US6001820A (en) * 1995-03-31 1999-12-14 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5763427A (en) * 1995-03-31 1998-06-09 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5767269A (en) * 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
IL129877A (en) * 1996-11-27 2004-08-31 Aventis Pharm Prod Inc A pharmaceutical preparation containing a component having an Xa antagonist activity and an antifouling agent
EP0986581A1 (en) * 1997-06-06 2000-03-22 Hamilton Civic Hospitals Research Development, Inc. Modified low molecular weight heparin that inhibits clot associated coagulation factors
EP1192187A1 (en) * 1999-06-30 2002-04-03 Hamilton Civic Hospitals Research Development, Inc. Heparin compositions that inhibit clot associated coagulation factors
JP4828795B2 (ja) 2002-03-11 2011-11-30 モメンタ ファーマシューティカルズ インコーポレイテッド 硫酸化多糖類の分析
EP1582531A1 (en) * 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
RU2295538C2 (ru) * 2005-03-01 2007-03-20 Гематологический научный центр РАМН Способ получения гепаринов с низкой молекулярной массой
ATE552004T1 (de) 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
RU2377993C2 (ru) * 2007-11-08 2010-01-10 Государственное учреждение гематологический научный центр Российской академии медицинских наук (ГУ ГНЦ РАМН) Способ получения низкомолекулярного гепарина
US8435795B2 (en) 2010-01-19 2013-05-07 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
CN102690862B (zh) * 2012-06-08 2015-01-28 上海太阳生物技术有限公司 抗凝血酶ⅲ(at-ⅲ)测定试剂盒(发色底物法)
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
EP3997238A1 (en) 2019-07-09 2022-05-18 Optimvia, LLC Methods for synthesizing anticoagulant polysaccharides
CN111763702A (zh) * 2020-07-13 2020-10-13 福州大学 一种制备硫酸乙酰肝素寡糖的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351938A (en) * 1980-05-19 1982-09-28 Riker Laboratories, Inc. Anticoagulant substance
US4396762A (en) * 1981-08-24 1983-08-02 Massachusetts Institute Of Technology Heparinase derived anticoagulants
DE3244214A1 (de) * 1982-11-30 1984-05-30 B. Braun Melsungen Ag, 3508 Melsungen Verfahren zur reinigung und fraktionierung von heparin
DK196986D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider

Also Published As

Publication number Publication date
DE3783644T2 (de) 1993-05-13
FI89943C (fi) 1993-12-10
IE871152L (en) 1987-10-30
NO167577C (no) 1991-11-20
JPH0542918B2 (da) 1993-06-30
EP0244235A2 (en) 1987-11-04
JPS62283102A (ja) 1987-12-09
NO871784D0 (no) 1987-04-29
GR3006929T3 (da) 1993-06-30
EP0244235A3 (en) 1988-09-28
AU7225387A (en) 1987-11-05
EP0244235B1 (en) 1993-01-20
FI89943B (fi) 1993-08-31
FI871909A0 (fi) 1987-04-29
IE60409B1 (en) 1994-07-13
NO871784L (no) 1987-11-02
ATE84801T1 (de) 1993-02-15
ES2052559T3 (es) 1994-07-16
FI871909L (fi) 1987-10-31
NO167577B (no) 1991-08-12
AU585709B2 (en) 1989-06-22
CA1334080C (en) 1995-01-24
DE3783644D1 (de) 1993-03-04

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