ATE552004T1 - Oral verabreichbare heparinderivate - Google Patents

Oral verabreichbare heparinderivate

Info

Publication number
ATE552004T1
ATE552004T1 AT05111534T AT05111534T ATE552004T1 AT E552004 T1 ATE552004 T1 AT E552004T1 AT 05111534 T AT05111534 T AT 05111534T AT 05111534 T AT05111534 T AT 05111534T AT E552004 T1 ATE552004 T1 AT E552004T1
Authority
AT
Austria
Prior art keywords
oral
heparine
derivatives
sulfation
acetylated
Prior art date
Application number
AT05111534T
Other languages
English (en)
Inventor
Giangiacomo Torri
Annamaria Naggi
Original Assignee
Istituto G Ronzoni
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto G Ronzoni filed Critical Istituto G Ronzoni
Application granted granted Critical
Publication of ATE552004T1 publication Critical patent/ATE552004T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT05111534T 2005-11-30 2005-11-30 Oral verabreichbare heparinderivate ATE552004T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05111534A EP1792621B1 (de) 2005-11-30 2005-11-30 Oral verabreichbare Heparinderivate

Publications (1)

Publication Number Publication Date
ATE552004T1 true ATE552004T1 (de) 2012-04-15

Family

ID=36010899

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05111534T ATE552004T1 (de) 2005-11-30 2005-11-30 Oral verabreichbare heparinderivate

Country Status (2)

Country Link
EP (1) EP1792621B1 (de)
AT (1) ATE552004T1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111257278A (zh) * 2018-11-30 2020-06-09 烟台东诚药业集团股份有限公司 一种近红外在线检测碱性降解肝素苄基酯降解程度的方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3766167A (en) 1971-03-26 1973-10-16 Research Corp Orally active anticoagulant
FR2478646A2 (fr) 1980-03-20 1981-09-25 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
DE2851333A1 (de) 1978-11-28 1980-06-12 Bosch Gmbh Robert Pruefschaltung fuer die ausloesevorrichtung einer den schutz der insassen eines fahrzeugs waehrend eines unfalles dienenden sicherheitseinrichtung
CA1136620A (en) 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity
US4826827A (en) 1979-10-05 1989-05-02 Choay S.A. Short chained oligosaccharides having biological properties, a process for making the same and the use thereof as drugs
FR2482611B1 (fr) 1980-05-14 1986-03-07 Pharmindustrie Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
FR2503714B1 (fr) 1981-04-10 1986-11-21 Choay Sa Procede d'obtention de mucopolysaccharides biologiquement actifs, de purete elevee, par depolymerisation de l'heparine
FR2504928A1 (fr) 1981-04-29 1982-11-05 Choay Sa Oligosaccharides a chaines courtes possedant des proprietes biologiques, leur preparation et leurs applications en tant que medicaments
US4396762A (en) 1981-08-24 1983-08-02 Massachusetts Institute Of Technology Heparinase derived anticoagulants
US4533549A (en) 1983-01-04 1985-08-06 Lasker Sigmund E Antithrombotic agent
IT1195497B (it) 1983-03-08 1988-10-19 Opocrin Spa Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina
FR2584728B1 (fr) 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
DK196886D0 (da) 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider
DK196986D0 (da) 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider
FR2614026B1 (fr) 1987-04-16 1992-04-17 Sanofi Sa Heparines de bas poids moleculaire, a structure reguliere, leur preparation et leurs applications biologiques
IT1234508B (it) 1988-06-10 1992-05-19 Alfa Wassermann Spa Derivati eparinici e procedimento per la loro preparazione
US4981955A (en) 1988-06-28 1991-01-01 Lopez Lorenzo L Depolymerization method of heparin
IT1230582B (it) 1988-10-21 1991-10-28 Opocrin S P A Lab Farmabiologi Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica
IT1234826B (it) 1989-01-30 1992-05-29 Alfa Wassermann Spa Derivati eparinici e procedimento per la loro preparazione
PT93847A (pt) 1989-04-24 1990-11-20 Harvard College Processo para a preparacao de oligossacaridos de baixo peso molecular derivados de heparina ou de sulfato de heparano despolimerizados e de composicoes farmaceuticas que os contem
DE4121115B9 (de) 1990-06-26 2005-09-29 Aventis Pharma S.A. Gemische sulfatierter Polysaccharide mit der Grundstruktur der das Heparin bildenden Polysaccharide und mit niedrigem Molekulargewicht, deren Herstellungsverfahren und Verwendung
FR2663639B1 (fr) 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
IT1244373B (it) 1991-01-18 1994-07-08 Sclavo Spa Composizioni farmaceutiche per uso orale contenenti eparina a basso peso molecolare, loro preparazione ed uso
FR2704861B1 (fr) 1993-05-07 1995-07-28 Sanofi Elf Fractions d'héparine purifiées, procédé d'obtention et compositions pharmaceutiques les contenant.
WO2000048589A1 (en) 1999-02-22 2000-08-24 Emisphere Holdings, Inc. Solid oral dosage form containing heparin or a heparinoid in combination with a carrier
WO2001034114A1 (en) 1999-11-12 2001-05-17 Emisphere Technologies, Inc. Liquid heparin formulation
ITMI20012599A1 (it) * 2001-12-11 2003-06-11 Cosmo Spa Composizioni farmaceutiche per la somministrazione orale di eparina osuoi derivati, utili per la terapia di malattie infiammatorie dell'int
EP1344781A1 (de) 2002-03-12 2003-09-17 Laboratori Derivati Organici S.P.A. Verfahren zur Depolymerisierung von Glykosaminoglykanen und so hergestellte Produkte
ITMI20021372A1 (it) 2002-06-21 2003-12-22 Derivati Organici Lab Processo per la depolimerizzazione fisica dei glicosamminogliacani e prodotti da esso ottenuti
EP1475391A1 (de) 2003-05-09 2004-11-10 Laboratori Derivati Organici S.P.A. Verfahren zur physikalischen Depolymerisation von Glykosaminoglykanen und dadurch erhaltene Produkte

Also Published As

Publication number Publication date
EP1792621A1 (de) 2007-06-06
EP1792621B1 (de) 2012-04-04

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